EKS-ANC-00234

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00234

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	336.1	1.1E-100	1	227	227

Status

Unreviewed

Ensembl Protein

ENSACAP00000001525

UniProt Accession

H9G5C1;

Protein Name

Protein Synonyms/Alias

Gene Name

SIK3

Gene Synonyms/Alias

SIK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000001502	ENSACAP00000001525	ENSACAT00000001561

Organism

Anolis carolinensis

Functional Description

Protein Length

1295

Protein Sequence
(FASTA)

QVAIKIIDKT QLDEENLKKI FREVQIMKML CHPHIIRLYQ VMETERMIYL VTEYASGGEI 60

FDHLVAHGRM AEKEARKKFK QIVAAVHFCH CRNIVHRDLK AENLLLDANL NIKIADFGFS 120

NKFTPGQLLK TWCGSPPYAA PELFEGKEYD GPKVDIWSLG VVLYVLVCGA LPFDGSTLQN 180

LRARVLSGKF RIPFFMSTEC EHLIRHMLVL EPSRRLSMEQ ICKHKWMKLG EADAEFDTLI 240

AECQHLKIER QMEPLNEEVL LAMAEMGLDK EHTLQSLSTD AYDHYSAIYS LLCDRQKRHK 300

NLRIPTQPGL PRALAFSAAA IASIQAEQGG NTVSISVPQV QLINPENQIV ETDGTMNLDS 360

DEGEEPSPEA LVRYLSMRRH TVGVADPRTE VMEDLQKLLP PGFPRVAPQA PFLQVAPNMN 420

MAANMLPMQH LQPSGQLEYK EQSLLQPPTL QLLNGMGPLG RRASDGGANI QLHAQQLLKR 480

PRGPSPLVTM TPAVPAVTPV DEEGSDGEPD QEAVQRYLAN RSKRHTLAMT NPTAEIPPDL 540

QRQLGQQPFR SRAPHMAPDQ HRYIYKDSNT LHLPTERFSP VRRFSDGAAS IQAFKAQLEK 600

MGNHSSIKQL QQECEQLRKM YGGHMDERTL EKTQQQHILY QQEQHHQILQ QQIQDCVCPP 660

QPSPPLQAPG ENQPALLTHQ LQRLRIQPSS PPPNHPSNHL FRQPDSSPPP TASSVHQSHG 720

AASPSLFQGM PSHGAIFQPS GSCSPPPGLA LSCLGPGQPA VAMQMQESGD MMGGLPVGPS 780

ANQLQMHHHR ASLMASLSYG PRPLSKQLSA DGTETTTHRL KLNKYPSSGY DQVHTHPHLF 840

PEQPRAPPGP YGPSTAVGFS PSQAMKVPQM EPFPAFTQSA QPLPPQQQHY ASALQQALLS 900

PTPPDYSRHQ QVPHFLQGLL SPRHSLTGHG DLRLPQAEVA QILKRRQQQQ QQQEFQELIR 960

HMSHGEGGHH AVSSVAQKLS ERHSLSLPYQ NTDSYHPHHG HHPQHHHTSP QHLLKVRAHD 1020

GLQAQGGAAH AYAPSPALLH SESMEEEEEE PEEEQEEAVA VDCACQGDRD AFLGSKTKAG 1080

RHHHHHHPHH HHHHEPQLLL SVGGPGDLEA FYGTAKHEAE MGHPYRAQPM AAAAFSRNEA 1140

PCRDSMVSGC MERHSSPRQV EMADAEGLGA YSARAIPGPH HRARPLQRHH TIQSSEDAYV 1200

QLDTLPGMSL MAGKVLSSAR MADAVLSQSS LMGSQPLHDG ERADGEEHLE GEEHLALGDS 1260

SQHLNASCYP STCITDVLLS YKHPEVPFSM EQAGV 1295

Nucleotide Sequence
(FASTA)

CAGGTGGCCA TAAAGATCAT CGACAAAACC CAGCTGGATG AGGAGAACCT CAAGAAGATC 60

TTCAGGGAAG TTCAGATCAT GAAGATGCTC TGCCACCCCC ACATCATCCG GCTGTATCAG 120

GTTATGGAGA CGGAGCGGAT GATTTATCTG GTGACGGAAT ATGCCAGCGG AGGGGAAATA 180

TTTGATCACT TGGTGGCCCA CGGGCGCATG GCCGAAAAGG AGGCACGGAA GAAGTTCAAG 240

CAGATTGTGG CCGCCGTGCA CTTCTGCCAC TGCCGCAACA TTGTCCACAG GGACCTCAAG 300

GCCGAGAACC TGCTCCTGGA TGCCAACCTG AACATCAAAA TCGCAGATTT TGGATTCAGT 360

AATAAATTCA CTCCGGGGCA GCTGCTGAAG ACTTGGTGTG GGAGCCCGCC GTACGCGGCT 420

CCAGAGCTTT TTGAGGGGAA GGAGTATGAC GGGCCAAAGG TGGACATCTG GAGCCTTGGC 480

GTGGTGCTCT ACGTGCTGGT CTGTGGGGCG TTGCCCTTTG ACGGGAGCAC GCTGCAGAAC 540

CTGCGGGCGA GGGTCCTGAG CGGGAAGTTC CGCATTCCGT TCTTCATGTC CACAGAGTGC 600

GAGCACTTGA TCCGCCACAT GTTGGTGCTG GAGCCCAGCC GGCGGCTCTC CATGGAGCAG 660

ATCTGCAAGC ACAAGTGGAT GAAGCTCGGG GAGGCGGACG CGGAGTTCGA CACGTTAATA 720

GCCGAGTGCC AGCACCTGAA GATCGAGCGG CAGATGGAGC CCCTGAACGA GGAGGTGCTG 780

CTGGCCATGG CCGAGATGGG GCTGGACAAG GAGCACACCT TGCAGTCGCT GAGCACGGAT 840

GCCTACGATC ACTACAGTGC CATCTACAGC CTGCTCTGCG ACCGACAGAA GAGGCATAAG 900

AACCTGCGGA TTCCCACGCA GCCTGGCCTG CCCAGGGCCT TGGCCTTCTC CGCAGCAGCC 960

ATCGCCAGCA TCCAGGCAGA GCAAGGAGGC AACACGGTGA GCATCAGTGT TCCTCAGGTG 1020

CAGCTCATCA ACCCGGAGAA CCAGATTGTG GAGACGGACG GGACCATGAA CCTGGACTCC 1080

GACGAAGGGG AAGAGCCCTC TCCCGAAGCC CTGGTCCGCT ACCTCTCCAT GCGCAGGCAC 1140

ACGGTGGGAG TGGCCGATCC TCGCACGGAG GTGATGGAGG ATCTCCAGAA ACTGCTGCCG 1200

CCGGGCTTCC CCCGCGTTGC GCCTCAGGCC CCCTTCCTGC AGGTGGCGCC AAACATGAAC 1260

ATGGCCGCCA ACATGCTGCC CATGCAGCAC CTCCAGCCCT CTGGCCAGTT GGAGTACAAG 1320

GAGCAGTCGT TGCTGCAGCC CCCAACTCTG CAGCTGCTGA ACGGGATGGG GCCCCTGGGG 1380

CGGAGGGCCT CGGACGGAGG GGCCAACATC CAGCTGCACG CCCAGCAGCT CCTCAAGCGG 1440

CCCCGGGGCC CTTCCCCACT GGTTACCATG ACACCAGCCG TGCCCGCCGT GACCCCAGTG 1500

GACGAGGAGG GCTCCGACGG AGAGCCGGAC CAGGAGGCCG TGCAGAGATA CTTGGCCAAT 1560

AGGTCCAAAA GGCACACCCT GGCAATGACC AACCCCACCG CGGAAATCCC GCCCGACTTG 1620

CAGAGGCAGC TAGGACAGCA GCCCTTCCGC TCCCGGGCTC CGCACATGGC ACCCGACCAG 1680

CACCGCTACA TCTACAAGGA CTCCAACACC TTGCACCTGC CCACCGAGCG CTTCTCCCCA 1740

GTCCGCCGCT TCTCCGACGG AGCCGCCAGC ATCCAGGCGT TTAAGGCCCA GCTGGAGAAG 1800

ATGGGCAACC ACAGCAGCAT CAAGCAGCTC CAGCAGGAGT GCGAGCAGCT CCGGAAGATG 1860

TACGGGGGAC ACATGGACGA GCGCACGCTG GAGAAGACGC AGCAGCAGCA CATCTTGTAC 1920

CAGCAGGAGC AGCACCACCA GATCCTCCAG CAGCAGATCC AGGACTGTGT CTGCCCCCCA 1980

CAGCCCTCTC CGCCCCTCCA AGCGCCCGGG GAGAACCAGC CCGCTCTGCT CACCCACCAG 2040

CTCCAGAGGT TGCGGATCCA GCCCTCCAGC CCTCCTCCCA ACCATCCCAG CAACCATCTC 2100

TTCAGGCAGC CCGACAGCAG CCCCCCTCCC ACCGCCAGCA GCGTCCACCA GAGCCATGGT 2160

GCTGCCTCCC CGTCTCTGTT CCAAGGGATG CCTTCTCACG GTGCCATCTT CCAGCCCTCG 2220

GGCAGCTGCT CCCCCCCGCC GGGCCTGGCC CTCTCTTGCC TGGGGCCGGG CCAGCCGGCG 2280

GTGGCCATGC AGATGCAGGA GAGCGGGGAC ATGATGGGCG GCCTGCCCGT CGGCCCCAGT 2340

GCCAACCAGC TGCAGATGCA CCACCACCGG GCCAGCCTCA TGGCCTCCCT CTCCTACGGG 2400

CCCAGGCCGC TCTCCAAGCA GCTCAGCGCC GACGGCACGG AGACGACCAC GCACAGATTA 2460

AAATTAAACA AGTATCCGTC CTCCGGCTAC GACCAGGTGC ACACGCATCC CCACCTCTTT 2520

CCGGAGCAGC CCCGGGCCCC TCCCGGCCCC TACGGCCCGT CCACAGCTGT GGGCTTCTCC 2580

CCCTCGCAGG CCATGAAAGT ACCGCAGATG GAGCCGTTCC CCGCCTTCAC CCAGAGCGCC 2640

CAGCCGCTCC CTCCACAGCA GCAGCACTAC GCCTCCGCCT TGCAGCAGGC CCTGCTCTCC 2700

CCGACGCCGC CGGACTACAG CCGGCACCAG CAAGTCCCAC ACTTCCTGCA GGGCCTGCTC 2760

TCTCCCCGAC ACTCGCTCAC GGGCCACGGG GACCTGCGGC TGCCCCAGGC AGAGGTGGCC 2820

CAGATCCTCA AGCGGCGGCA GCAGCAGCAG CAGCAGCAGG AGTTCCAGGA GCTGATCCGG 2880

CACATGAGCC ACGGGGAGGG CGGGCACCAC GCCGTGTCCA GCGTGGCCCA GAAACTGTCG 2940

GAGCGCCACT CCCTCTCCTT GCCTTACCAG AACACGGACT CGTACCACCC GCACCACGGC 3000

CACCACCCCC AGCACCACCA CACCAGCCCC CAGCACCTCC TGAAAGTGCG GGCGCACGAC 3060

GGCCTCCAGG CGCAGGGGGG GGCGGCCCAT GCGTACGCCC CCTCGCCCGC CCTGCTCCAC 3120

TCGGAAAGCA TGGAAGAGGA GGAGGAGGAG CCGGAGGAGG AGCAGGAGGA GGCCGTGGCG 3180

GTGGACTGCG CCTGCCAGGG GGACAGGGAC GCCTTTCTGG GCAGCAAGAC CAAAGCGGGC 3240

CGCCACCACC ACCACCACCA TCCCCACCAC CACCACCACC ACGAGCCCCA GCTGCTCCTG 3300

AGTGTGGGTG GCCCGGGGGA CCTGGAGGCC TTTTATGGGA CCGCTAAGCA CGAGGCGGAA 3360

ATGGGCCACC CTTACCGGGC CCAGCCCATG GCGGCAGCCG CCTTCAGCCG GAACGAGGCT 3420

CCCTGCCGAG ACTCCATGGT GTCCGGCTGC ATGGAGCGGC ACTCCTCGCC CCGGCAGGTG 3480

GAGATGGCCG ACGCAGAGGG GCTGGGGGCT TATTCGGCCA GGGCCATCCC CGGACCGCAC 3540

CACAGAGCCC GGCCTCTGCA GAGACACCAC ACCATCCAGA GCAGCGAGGA CGCCTACGTG 3600

CAACTGGACA CCCTGCCGGG CATGAGCCTC ATGGCGGGGA AGGTGCTCAG CTCCGCCCGC 3660

ATGGCCGACG CCGTGCTCAG CCAGTCCTCC CTGATGGGCA GCCAGCCGCT CCACGACGGG 3720

GAGAGGGCAG ACGGCGAGGA ACATTTGGAA GGAGAGGAGC ACCTGGCCCT GGGGGACAGC 3780

AGCCAGCACC TGAACGCCTC TTGCTACCCC TCCACCTGCA TCACGGACGT CCTGCTGAGC 3840

TACAAGCACC CGGAGGTGCC CTTCAGCATG GAGCAAGCCG GGGTCTAG 3888

Domain Profile

S: 26    kvavKiikkkklseeslekikrEieilkklkhpniikllevietkkklylvleyasggeL  85

         +va+Kii+k++l+ee+l+ki+rE++i+k+l hp+ii+l++v+et++++ylv+eyasgge+

Q: 1     QVAIKIIDKTQLDEENLKKIFREVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEI  60

         69**********************************************************

S: 86    fdyieekgrlkekearklfkqlvsavkYlhskgivHrDlKpeNllldkkenikiaDFGla  145

         fd+++++gr+ ekeark fkq+v+av+++h ++ivHrDlK+eNllld++ nikiaDFG++

Q: 61    FDHLVAHGRMAEKEARKKFKQIVAAVHFCHCRNIVHRDLKAENLLLDANLNIKIADFGFS  120

         ************************************************************

S: 146   nlfkegklletfcGsppYaaPellkgkkYegpkvDvWslGvvLyalvtgklPfdeenlke  205

         n+f++g+ll+t+cGsppYaaPel++gk+Y+gpkvD+WslGvvLy+lv+g+lPfd+++l++

Q: 121   NKFTPGQLLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQN  180

         ************************************************************

S: 206   llekilkgkleipkklskelesLlrklLvvdpekRatieeilkhewl  252

         l++++l+gk++ip+ +s+e+e+L+r++Lv +p++R+++e+i kh+w+

Q: 181   LRARVLSGKFRIPFFMSTECEHLIRHMLVLEPSRRLSMEQICKHKWM  227

         **********************************************8

Domain Sequence
(FASTA)

QVAIKIIDKT QLDEENLKKI FREVQIMKML CHPHIIRLYQ VMETERMIYL VTEYASGGEI 60

FDHLVAHGRM AEKEARKKFK QIVAAVHFCH CRNIVHRDLK AENLLLDANL NIKIADFGFS 120

NKFTPGQLLK TWCGSPPYAA PELFEGKEYD GPKVDIWSLG VVLYVLVCGA LPFDGSTLQN 180

LRARVLSGKF RIPFFMSTEC EHLIRHMLVL EPSRRLSMEQ ICKHKWM 227

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR015940	; UBA/transl_elong_EF1B_N_euk.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50030	; UBA; 1.

Prints

Created Date

20-Feb-2013