EKS-ANC-00135

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00135

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/CDC7	500.7	1.4E-150	24	532	509

Status

Unreviewed

Ensembl Protein

ENSACAP00000001488

UniProt Accession

G1K9L3;

Protein Name

Protein Synonyms/Alias

Gene Name

CDC7

Gene Synonyms/Alias

CDC7;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000001503	ENSACAP00000001488	ENSACAT00000001524

Organism

Anolis carolinensis

Functional Description

Protein Length

537

Protein Sequence
(FASTA)

NFSLGASTDI EKLYEAVPQL GNLFKIKGKI GEGTFSSVYL AVAQGRGNQE EKVALKHLIP 60

TSHPVRIAAE LQCLIVAGGQ DNVMGVKCCF RKNDHVVIVM PYLEHESFLD ILNSLSFEEV 120

RDYMFNLLKA LKRIHHFGIV HRDVKPSNFL YNQQLKQYAL VDFGLAQGTP ETKIELLKVI 180

QSEAPQGSCT YTKPQITLGS QVSVTSTAPR HSTHQSATKT ANKRPCSASQ TQIKEGHKMQ 240

EGQECFAHQR SVFGERNFNV RSPAFQDRST VKLVKQPKVT DIPSRKLSAK KKATSTLNNG 300

LAKKAASSCP ANLTCDCYAK DRVCSICLSR RQQVAPRAGT PGFRAPEVLI KCPHQSTAID 360

IWSAGIIFLS LLSDRYPFYK AGDDLTALAQ IMTIRGSRET IQAARTFGKS ILCSKEIVAQ 420

DLRKLCERLR GNSTSFDNST GDVQIKPQES ALPAEISNAF EASLQGPQKH IHYQKQHHHG 480

GDGRDVRITE KGADPKGWDN VPDEAYDLLD KLLDLNPATR ITAKDALLHP FFRNMKQ 537

Nucleotide Sequence
(FASTA)

AATTTCTCAC TAGGAGCAAG CACAGATATT GAAAAACTTT ATGAAGCAGT ACCGCAGCTT 60

GGAAATCTGT TCAAAATTAA AGGAAAAATT GGTGAAGGTA CCTTTAGTTC TGTTTATTTA 120

GCTGTAGCCC AAGGGCGAGG AAACCAAGAA GAAAAAGTGG CTTTGAAACA CTTGATTCCC 180

ACCAGTCATC CTGTACGAAT TGCTGCTGAA CTTCAGTGTC TTATAGTAGC AGGGGGCCAG 240

GATAATGTTA TGGGAGTTAA GTGTTGTTTT AGAAAAAATG ATCACGTGGT TATTGTTATG 300

CCATATCTGG AACACGAATC CTTTTTGGAC ATCTTGAACT CGCTCTCCTT TGAAGAAGTA 360

AGAGATTATA TGTTTAATCT CCTTAAAGCT TTGAAGCGTA TTCATCACTT TGGTATTGTT 420

CATCGTGATG TCAAGCCCAG TAACTTTCTA TACAACCAGC AACTGAAACA ATATGCCTTG 480

GTCGACTTTG GCTTGGCCCA AGGAACTCCG GAGACCAAAA TAGAACTTCT CAAAGTTATC 540

CAATCTGAAG CCCCTCAGGG AAGTTGCACG TATACTAAGC CTCAAATAAC TTTGGGAAGC 600

CAGGTGTCTG TCACTTCCAC GGCACCTAGA CACTCAACTC ATCAGTCAGC TACAAAAACT 660

GCCAATAAAA GACCTTGTTC TGCTTCACAA ACCCAGATTA AAGAAGGACA CAAAATGCAG 720

GAGGGGCAAG AGTGCTTTGC TCATCAGCGC TCTGTCTTTG GAGAGAGGAA TTTCAATGTC 780

CGAAGTCCTG CATTTCAGGA CCGTTCCACA GTTAAACTTG TAAAACAGCC CAAAGTGACA 840

GATATTCCAT CTAGAAAACT GTCAGCAAAG AAGAAGGCAA CTTCAACTCT GAATAACGGG 900

TTAGCCAAGA AAGCTGCCAG CAGTTGTCCA GCGAACTTGA CCTGCGACTG TTATGCAAAA 960

GATAGAGTCT GCAGTATTTG TCTTTCGAGG CGTCAGCAAG TTGCTCCAAG GGCTGGTACA 1020

CCTGGATTCA GAGCACCAGA GGTATTAATC AAGTGTCCTC ACCAGTCTAC AGCAATTGAC 1080

ATATGGTCTG CAGGAATAAT ATTTCTTTCT CTGCTGAGTG ATCGGTATCC ATTTTACAAA 1140

GCGGGCGATG ATTTAACAGC TCTGGCACAG ATTATGACTA TTCGTGGATC CAGGGAAACA 1200

ATTCAAGCTG CTAGGACATT TGGTAAATCA ATCCTGTGTA GCAAAGAAAT CGTGGCTCAG 1260

GATTTACGAA AACTCTGTGA GAGGCTGAGA GGGAACAGTA CCAGCTTTGA CAACTCGACA 1320

GGAGATGTTC AGATCAAACC TCAGGAATCT GCTTTGCCAG CGGAAATCAG CAATGCTTTT 1380

GAGGCTTCAC TCCAGGGTCC CCAAAAGCAC ATACATTACC AGAAGCAGCA TCATCATGGA 1440

GGCGATGGTA GAGATGTGAG GATTACTGAA AAAGGAGCTG ATCCAAAAGG ATGGGACAAC 1500

GTTCCCGACG AGGCCTATGA TCTTCTTGAT AAACTGCTTG ACTTAAATCC TGCTACAAGA 1560

ATCACTGCCA AGGATGCTTT ACTACATCCC TTTTTCAGAA ATATGAAGCA ATAA 1614

Domain Profile

S: 1     fkikdkiGeGtfssvylataqleegleekialkhliptshPeriaaeLelltvlgGqenv  60

         fkik kiGeGtfssvyla aq + ++eek+alkhliptshP riaaeL++l v+gGq+nv

Q: 24    FKIKGKIGEGTFSSVYLAVAQGRGNQEEKVALKHLIPTSHPVRIAAELQCLIVAGGQDNV  83

         9***********************************************************

S: 61    vglkecfrkndsvvivlpylehesfldllrslsfqevreYlrnLlvalkrvhkfgivhrD  120

         +g+k+cfrknd+vviv+pylehesfld+l+slsf+evr+Y++nLl+alkr+h+fgivhrD

Q: 84    MGVKCCFRKNDHVVIVMPYLEHESFLDILNSLSFEEVRDYMFNLLKALKRIHHFGIVHRD  143

         ************************************************************

S: 121   vkpsnfLynrrlkkfaLvDfGLaq..............seaqkeecsrn..........l  156

         vkpsnfLyn++lk++aLvDfGLaq              sea + +c+ +

Q: 144   VKPSNFLYNQQLKQYALVDFGLAQgtpetkiellkviqSEAPQGSCTYTkpqitlgsqvS  203

         **************************************9999999998866665555443

S: 157   lsaavekevd..................................................  166

         +++      +

Q: 204   VTS------Taprhsthqsatktankrpcsasqtqikeghkmqegqecfahqrsvfgern  257

         333......24444558888888999999999999999**********************

S: 167   ........................................................tcdc  170

                                                                 tcdc

Q: 258   fnvrspafqdrstvklvkqpkvtdipsrklsakkkatstlnnglakkaasscpanlTCDC  317

         ************************************************************

S: 171   ygtdkvcsvclsrrqqvanraGtpGfraPevLlkipdqttaiDiwsaGvilLsllsgryP  230

         y+ d+vcs+clsrrqqva+raGtpGfraPevL+k+p+q+taiDiwsaG+i+Lslls ryP

Q: 318   YAKDRVCSICLSRRQQVAPRAGTPGFRAPEVLIKCPHQSTAIDIWSAGIIFLSLLSDRYP  377

         ************************************************************

S: 231   ffkasddlealaeivtilGsreiikaakafgksvllskevp...................  271

         f+ka ddl+ala+i+ti+Gsre+i+aa++fgks+l+ske+

Q: 378   FYKAGDDLTALAQIMTIRGSRETIQAARTFGKSILCSKEIVaqdlrklcerlrgnstsfd  437

         ****************************************999****************9

S: 272   .......................................................dsdsy  276

Q: 438   nstgdvqikpqesalpaeisnafeaslqgpqkhihyqkqhhhggdgrdvritekgA----  493

         99999999999999999999999999999998888877777777666666655551....

S: 277   e.......PdeaydlldkllelnPakritaeealkhpff  308

                 Pdeaydlldkll+lnPa rita++al+hpff

Q: 494   DpkgwdnvPDEAYDLLDKLLDLNPATRITAKDALLHPFF  532

         04555667******************************8

Domain Sequence
(FASTA)

FKIKGKIGEG TFSSVYLAVA QGRGNQEEKV ALKHLIPTSH PVRIAAELQC LIVAGGQDNV 60

MGVKCCFRKN DHVVIVMPYL EHESFLDILN SLSFEEVRDY MFNLLKALKR IHHFGIVHRD 120

VKPSNFLYNQ QLKQYALVDF GLAQGTPETK IELLKVIQSE APQGSCTYTK PQITLGSQVS 180

VTSTAPRHST HQSATKTANK RPCSASQTQI KEGHKMQEGQ ECFAHQRSVF GERNFNVRSP 240

AFQDRSTVKL VKQPKVTDIP SRKLSAKKKA TSTLNNGLAK KAASSCPANL TCDCYAKDRV 300

CSICLSRRQQ VAPRAGTPGF RAPEVLIKCP HQSTAIDIWS AGIIFLSLLS DRYPFYKAGD 360

DLTALAQIMT IRGSRETIQA ARTFGKSILC SKEIVAQDLR KLCERLRGNS TSFDNSTGDV 420

QIKPQESALP AEISNAFEAS LQGPQKHIHY QKQHHHGGDG RDVRITEKGA DPKGWDNVPD 480

EAYDLLDKLL DLNPATRITA KDALLHPFF 509

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0008284	; P:positive regulation of cell proliferation
GO:0033261	; P:regulation of S phase

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 2.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013