EKS-ANC-00200

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00200

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	526.6	1.1E-158	4	287	284

Status

Unreviewed

Ensembl Protein

ENSACAP00000001774

UniProt Accession

H9G5N0;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL1

Gene Synonyms/Alias

CDKL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000001810	ENSACAP00000001774	ENSACAT00000001817

Organism

Anolis carolinensis

Functional Description

Protein Length

358

Protein Sequence
(FASTA)

MEKYEKISKI GEGSYGVVFK CRNRDTGQVV AIKKFLESED DPVIKKIALR EIRMLKQLKH 60

PNLVNLLEVF RRKRKLHLVF EYCDHTVLHE LDKNPRGVPE HLVKSITWQT LQAVNFCHKH 120

NCIHRDVKPE NILITKHFVI KLCDFGFARI LTGPSDYYTD YVATRWYRSP ELLVGDTQYG 180

PPVDVWAIGC VFAELLSGIP LWPGKSDVDQ LYLIRRTLGD LIPRHQQVFS TNQFFSGVRI 240

PDPESMEPLE MKFPSISYSA LGLMKGCLHM DPAERLTCEQ LLQHSYFDGI RDVELGRERS 300

MTRKPSRPTR KHIPGICLGN KQSLQYLPQL TSSNILPALD NKKYYCGMRK LNYRFPNI 358

Nucleotide Sequence
(FASTA)

ATGGAGAAGT ACGAAAAGAT CAGCAAGATC GGGGAGGGCT CCTACGGGGT GGTCTTCAAG 60

TGCCGGAACA GGGACACCGG GCAGGTCGTG GCCATCAAGA AGTTCCTGGA GTCGGAAGAC 120

GACCCCGTCA TTAAGAAGAT CGCCCTCCGA GAGATACGCA TGCTCAAGCA ACTGAAGCAT 180

CCCAACCTGG TCAACCTCTT GGAGGTCTTC CGTCGGAAGA GGAAGCTGCA CCTGGTCTTT 240

GAATATTGCG ACCACACTGT GCTGCACGAG CTGGACAAGA ACCCACGGGG GGTCCCAGAG 300

CATTTGGTGA AGAGCATAAC GTGGCAGACT CTCCAGGCGG TCAACTTTTG CCATAAACAC 360

AATTGCATAC ACAGAGATGT GAAGCCGGAA AACATCCTCA TCACAAAGCA TTTCGTCATT 420

AAACTCTGTG ACTTTGGATT CGCTCGCATC TTAACTGGAC CCAGCGATTA CTACACGGAT 480

TATGTGGCAA CTCGTTGGTA CCGTTCTCCC GAACTGCTTG TGGGGGACAC CCAGTACGGG 540

CCTCCCGTGG ACGTCTGGGC CATTGGCTGC GTCTTCGCTG AGCTGCTGTC CGGCATCCCG 600

TTGTGGCCGG GGAAATCCGA CGTGGACCAG CTCTACCTGA TCCGGAGGAC TTTGGGGGAC 660

CTCATTCCCA GGCACCAGCA GGTCTTCAGC ACCAACCAGT TCTTCAGTGG GGTCAGAATC 720

CCGGATCCAG AGAGCATGGA GCCTCTGGAA ATGAAATTCC CATCCATTTC TTATTCCGCC 780

CTCGGACTCA TGAAGGGCTG CCTTCACATG GATCCGGCTG AGCGGCTGAC CTGTGAGCAG 840

CTCCTGCAAC ATTCCTATTT TGATGGCATC CGTGACGTGG AGCTGGGGAG GGAGCGGTCC 900

ATGACACGGA AGCCCAGCCG GCCGACCCGG AAGCACATCC CTGGGATCTG TTTGGGGAAT 960

AAACAAAGCT TGCAGTACCT TCCCCAGTTA ACCAGCAGCA ACATCTTGCC TGCTTTGGAC 1020

AACAAGAAGT ACTACTGCGG GATGAGAAAA CTGAACTACC GTTTCCCTAA CATCTAA 1077

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yek++k+GeGsyGvv+kcrn+dtgq+vaikkflesedd+++kkialrei++lkqlkh+nl

Q: 4     YEKISKIGEGSYGVVFKCRNRDTGQVVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllevfrrk+kl+lvfey+d+tvl+el+++p+Gv+e+lvk+i++q+l+a++fchk+n+i

Q: 64    VNLLEVFRRKRKLHLVFEYCDHTVLHELDKNPRGVPEHLVKSITWQTLQAVNFCHKHNCI  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k+ v+klcdfGfar+l++p+d+ytdyvatrwyr+pellvgdt+yG++v

Q: 124   HRDVKPENILITKHFVIKLCDFGFARILTGPSDYYTDYVATRWYRSPELLVGDTQYGPPV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGc++aell+G pl+pgksdvdqly+ir+tlG+liprhq++fs+n++f+Gv++p++

Q: 184   DVWAIGCVFAELLSGIPLWPGKSDVDQLYLIRRTLGDLIPRHQQVFSTNQFFSGVRIPDP  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         e++e+le k+p++++++l l+k+cl++dpaerl+ce+ll+h+yf

Q: 244   ESMEPLEMKFPSISYSALGLMKGCLHMDPAERLTCEQLLQHSYF  287

         *******************************************9

Domain Sequence
(FASTA)

YEKISKIGEG SYGVVFKCRN RDTGQVVAIK KFLESEDDPV IKKIALREIR MLKQLKHPNL 60

VNLLEVFRRK RKLHLVFEYC DHTVLHELDK NPRGVPEHLV KSITWQTLQA VNFCHKHNCI 120

HRDVKPENIL ITKHFVIKLC DFGFARILTG PSDYYTDYVA TRWYRSPELL VGDTQYGPPV 180

DVWAIGCVFA ELLSGIPLWP GKSDVDQLYL IRRTLGDLIP RHQQVFSTNQ FFSGVRIPDP 240

ESMEPLEMKF PSISYSALGL MKGCLHMDPA ERLTCEQLLQ HSYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013