EKS-ANC-00303

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00303

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	349.2	1.3E-104	208	456	249

Status

Unreviewed

Ensembl Protein

ENSACAP00000001988

UniProt Accession

H9G5W4;

Protein Name

Protein Synonyms/Alias

Gene Name

PAK1

Gene Synonyms/Alias

PAK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000001968	ENSACAP00000001988	ENSACAT00000002036

Organism

Anolis carolinensis

Functional Description

Protein Length

458

Protein Sequence
(FASTA)

KANKKKEKER PEISLPSDFE HTIHVGFDAV TGEFTGMPEQ WARLLQTSNI TKLEQKKNPQ 60

AVLDVLEFYN SKKTSNSQKY MSFTDKSIED YNSSNTVNVK AVSETPAVPP VSEDEDDEDE 120

ATPPPVIAPR PEHTKSIYTR SVIEPLPPAP TRDVATSPLP SPTENNTTPP DTLTRNVEKQ 180

KKKPKMTDEE ILEKLRGIVS VGDPKKKYTS FEKIGQGASG TVYTAMDVAT GQEVAIKQMN 240

LQQQPKKELI INEILVMREN KNPNIVNYLD SYLVGDELWV VMEYLAGGSL TDVVTETCMD 300

EGQIAAVCRE CLQALEFLHS NQVIHRDIKS DNILLGMDGS VKLTDFGFCA QITPEQSKRS 360

TMVGTPYWMA PEVVTRKAYG PKVDIWSLGI MAIEMIEGEP PYLNENPLRA LYLIATNGTP 420

ELQNPEKLSP IFRDFLNRCL EMDVEKRGSA NELLQVRL 458

Nucleotide Sequence
(FASTA)

AAAGCCAATA AAAAGAAGGA GAAAGAACGA CCCGAGATCT CCCTGCCTTC AGACTTTGAG 60

CACACCATTC ACGTTGGATT TGATGCTGTC ACTGGTGAAT TTACGGGCAT GCCAGAGCAA 120

TGGGCCCGCT TGCTGCAAAC CTCCAATATC ACCAAACTGG AACAGAAGAA GAACCCCCAA 180

GCCGTACTTG ACGTTCTTGA ATTCTACAAC TCCAAGAAGA CCTCCAACAG CCAGAAATAC 240

ATGAGCTTCA CTGATAAATC CATCGAAGAT TATAATTCCT CCAACACAGT GAATGTGAAG 300

GCGGTGTCCG AGACTCCAGC TGTTCCCCCC GTTTCGGAAG ACGAGGATGA TGAAGATGAG 360

GCCACTCCAC CCCCAGTCAT TGCCCCCCGG CCAGAGCACA CCAAGTCGAT ATATACCCGG 420

TCAGTGATCG AGCCCCTTCC ACCAGCTCCG ACCCGAGACG TGGCCACCTC TCCGCTTCCC 480

TCTCCGACAG AGAACAACAC GACCCCCCCG GATACGCTGA CGAGGAACGT GGAGAAACAG 540

AAGAAGAAGC CCAAAATGAC CGACGAGGAG ATCTTGGAAA AATTGAGAGG CATCGTAAGT 600

GTAGGTGATC CCAAGAAGAA ATATACCAGT TTTGAGAAGA TTGGACAAGG TGCTTCAGGG 660

ACCGTTTATA CAGCCATGGA TGTAGCTACA GGACAAGAGG TTGCTATCAA ACAGATGAAC 720

CTGCAGCAGC AGCCCAAGAA AGAGCTGATC ATTAATGAAA TTCTGGTCAT GAGGGAAAAC 780

AAGAACCCCA ACATCGTCAA CTATTTGGAC AGTTACCTGG TGGGGGATGA GCTGTGGGTC 840

GTCATGGAGT ATTTGGCGGG AGGCTCGTTG ACAGACGTCG TGACGGAGAC CTGCATGGAC 900

GAAGGACAGA TCGCCGCTGT GTGTCGAGAG TGTCTTCAAG CTTTGGAATT CCTCCACTCC 960

AACCAGGTTA TCCACCGGGA CATTAAAAGC GACAATATCC TTCTAGGGAT GGATGGCTCA 1020

GTCAAGCTAA CTGATTTCGG CTTCTGTGCT CAGATCACTC CAGAGCAGAG CAAGCGCAGC 1080

ACCATGGTGG GGACACCGTA TTGGATGGCT CCCGAGGTGG TGACAAGAAA GGCTTATGGG 1140

CCCAAGGTGG ACATCTGGTC GCTGGGGATC ATGGCCATTG AAATGATTGA GGGGGAGCCT 1200

CCGTATCTCA ACGAGAATCC CTTGAGGGCT TTGTATCTCA TTGCCACCAA TGGCACGCCT 1260

GAGCTGCAGA ACCCGGAGAA GCTTTCGCCC ATATTTAGAG ACTTTCTCAA TCGCTGCCTT 1320

GAGATGGATG TGGAGAAGAG GGGGTCTGCT AACGAACTCC TCCAGGTAAG GCTG 1374

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkklkhpnive  60

         y+ +e+ig+Ga+g+vy+a ++ tg+ vaik++nl++q+k+e++++ei v+++ k+pniv+

Q: 208   YTSFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVN  267

         7889********************************************************

S: 61    ylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkvi  120

         yl+s+l+ +elw+vmeylagGsl+d+v+   ++ ++E qia+++re+l+aLe+lHs++vi

Q: 268   YLDSYLVGDELWVVMEYLAGGSLTDVVT---ETCMDEGQIAAVCRECLQALEFLHSNQVI  324

         ****************************...9****************************

S: 121   HrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYdek  180

         Hrdik++niLl ++g+VkL+dfg++aq++ +++kr+t+vgtpywmAPEv++  +k Y  k

Q: 325   HRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT--RKAYGPK  382

         ***************************************************..9******

S: 181   aDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclqk  240

         +DiwslGI+aie++egepP+ +++pl+al++i++n +p+l++++k+s+ f++f+++cl+

Q: 383   VDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRCLEM  442

         ************************************************************

S: 241   npekRpsasellkh  254

         ++ekR sa+ell+

Q: 443   DVEKRGSANELLQV  456

         ***********985

Domain Sequence
(FASTA)

YTSFEKIGQG ASGTVYTAMD VATGQEVAIK QMNLQQQPKK ELIINEILVM RENKNPNIVN 60

YLDSYLVGDE LWVVMEYLAG GSLTDVVTET CMDEGQIAAV CRECLQALEF LHSNQVIHRD 120

IKSDNILLGM DGSVKLTDFG FCAQITPEQS KRSTMVGTPY WMAPEVVTRK AYGPKVDIWS 180

LGIMAIEMIE GEPPYLNENP LRALYLIATN GTPELQNPEK LSPIFRDFLN RCLEMDVEKR 240

GSANELLQV 249

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Tursiops truncatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000095	; PAK_box_Rho-bd.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00786	; PBD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00285	; PBD; 1.
SM00220	; S_TKc; 1.

Prosites

PS50108	; CRIB; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013