EKS-ANC-00422

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00422

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	314.3	6.5E-94	4	254	251

Status

Unreviewed

Ensembl Protein

ENSACAP00000002909

UniProt Accession

G1KBE4;

Protein Name

Protein Synonyms/Alias

Gene Name

STK36

Gene Synonyms/Alias

STK36;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000002906	ENSACAP00000002909	ENSACAT00000002983
ENSACAG00000002906	ENSACAP00000019826	ENSACAT00000027919

Organism

Anolis carolinensis

Functional Description

Protein Length

1328

Protein Sequence
(FASTA)

MEQYHVLEMI GEGSFGRVYK GRRKYTTKIV ALKFIPKVGR SQKELKNLQR EIEIMRGLHH 60

PNIVQMLDSF ETDKEVVVVT DYAEGELFQI LEDDGNLPEE QVQIIASQLV SALYYLHSHR 120

ILHRDMKPQN ILLGKGGVIK LCDFGFARAM SIHTMVLTSI KGTPLYMSPE LVEEKPYDHT 180

ADLWSVGCIL YELYVGTPPF YTNSIFQLVS LIIKDPVKWP KNMSLHFKSF LQGLLMKNPH 240

ERLSWPELLY HPFIAGKVTV IDDTVDQGIV NPFTSKLPPD LQALKEQQAH SLTPPSGQSK 300

ILRKARQKMA QEARRKEMGK PKASLKGEVS KESETYSRKA CLAQTDSSRQ HQKLPGMEEH 360

LALGEKETEW EQKEPSSKLH LSSIFSMDRE NWITQDYERE FQEMKPESCR IKTRGRRSID 420

TVDLETEEMD SDEEWQHFID ATNSTHVHLS APLSLLGDPA FVQRIRVRLK DSGQQVLEGM 480

LEGASHLRPA LHVISNLLGT CCDSDLLCSF CNDIGLPQFL MQLVESILKS FNIKQQPWHI 540

TLLTDLMAVM TVFFASDFNR EKDGKKQSLQ AFQSSANHFL TLLPALLAQP TDQEGRLREQ 600

SLVCFTHLCQ SMDNACPSIS IPFYTSLLEN HCPLLDTLCH GVSCEQIIQE VPPKEARSKQ 660

HWNELMGAAF AKALAASCVI PGRHTVCQKA KKKISQYIAE KLTEKENRLL ASLILAVNHP 720

ASSLHGLKVL YACGHVSQTL CHHLATPEML NSLICHLQGK VFIHSYVQTA EASLRLFSLL 780

MLQLQFLPSQ SDIVLNETMK LFNSGATASV LSAAALLLTY FIQHGAAVKL RWEEALTAIA 840

TAFTESAEPC LPPPMGVGFY DGLLILLLHV LSEQGDVAMV REFAASELWG IVWHLFAMVL 900

HMTTQEPMLE GETSGAGQHA PEPDWDLISP QGTPFFLSLT LFVFTCEPHQ CLLQMAQPNG 960

LIMAVLNKLL DPDFLECLAQ MQLHEDGDLE LVTTTVLQVC QVFCFAFAMD MDPEILEQIL 1020

TNMKGSEIPA QLLQVCIHHL PCTKTELPLS LLCRLVLSDE EIIEQVVGAA TSQDAIDFLS 1080

SIFLSDQVHL LADLLTLLTH IARASPSHLP FLEKLLSGST SQALSHLLGH SECLVRARTC 1140

SLVGNLLRHG QEFPHILQGQ VGLLKSLLER LSDEDRHVRR SASFAVGNAA YQAGPFMQDL 1200

RKAVPCVVRL LGDPQAKTRC NAASALGNLG WQSVELGDSL IQNKAPNILL DVACHDSQPA 1260

VQKAALIALR SMSHQPRIRQ VLVSLRACEK LEALTLDQFQ NSAYSHPWPS STQHCKKLIQ 1320

LLQPSQSA 1328

Nucleotide Sequence
(FASTA)

ATGGAACAAT ATCATGTGTT GGAGATGATT GGAGAAGGCT CTTTTGGAAG GGTATATAAG 60

GGACGTCGCA AATACACCAC AAAGATTGTG GCTTTGAAGT TTATCCCCAA AGTGGGTCGG 120

TCACAGAAAG AGCTGAAGAA TTTGCAGCGA GAAATTGAGA TAATGAGGGG CCTTCATCAT 180

CCCAATATTG TCCAGATGCT TGACAGTTTT GAGACTGATA AAGAGGTGGT GGTAGTGACA 240

GATTATGCTG AAGGGGAACT CTTTCAGATC CTTGAAGATG ATGGGAACTT GCCTGAGGAG 300

CAGGTTCAGA TTATTGCCTC TCAGTTGGTG TCAGCACTCT ATTACCTACA CTCCCATCGG 360

ATCCTCCACC GTGACATGAA ACCTCAAAAC ATCTTACTGG GAAAAGGAGG TGTAATCAAA 420

CTCTGTGACT TTGGGTTTGC CCGTGCAATG AGTATTCACA CCATGGTACT GACATCTATC 480

AAAGGAACAC CACTATATAT GTCCCCCGAG TTAGTAGAGG AGAAGCCATA TGACCACACA 540

GCTGACTTGT GGTCAGTGGG ATGCATCCTG TATGAATTGT ATGTGGGGAC TCCCCCCTTC 600

TACACTAACA GCATCTTCCA GTTGGTCAGC CTGATCATCA AGGATCCTGT CAAGTGGCCA 660

AAAAATATGA GCCTGCACTT CAAGAGCTTT TTGCAAGGTC TGCTGATGAA AAACCCTCAT 720

GAACGTCTGT CCTGGCCAGA GCTGCTCTAT CATCCCTTCA TTGCTGGGAA AGTCACTGTG 780

ATTGATGACA CAGTAGATCA AGGCATAGTG AACCCCTTCA CCAGCAAATT GCCCCCTGAT 840

TTGCAGGCCT TGAAGGAGCA GCAGGCACAT TCACTTACCC CTCCAAGTGG GCAGTCTAAA 900

ATCTTGAGGA AGGCACGGCA GAAGATGGCC CAGGAAGCGC GGCGAAAGGA GATGGGGAAA 960

CCCAAGGCTT CACTTAAGGG AGAAGTTTCC AAAGAGAGTG AAACCTACTC ACGTAAGGCT 1020

TGCCTTGCTC AGACAGATAG TAGCAGACAG CATCAAAAAC TTCCTGGCAT GGAAGAGCAC 1080

CTTGCTTTAG GAGAAAAGGA AACAGAATGG GAGCAAAAAG AACCATCCTC CAAGCTACAC 1140

CTCTCCTCCA TCTTCTCCAT GGACAGAGAG AACTGGATCA CACAGGATTA TGAACGTGAA 1200

TTCCAAGAAA TGAAGCCTGA AAGTTGCAGA ATAAAGACCC GAGGCAGACG CAGCATTGAT 1260

ACTGTTGATC TGGAAACTGA GGAGATGGAT AGTGATGAAG AATGGCAACA CTTCATAGAT 1320

GCCACAAATT CTACACATGT GCACCTCAGT GCCCCACTGA GCCTTCTGGG AGATCCTGCA 1380

TTTGTTCAGC GGATCAGGGT CCGGCTCAAG GATTCTGGTC AACAGGTCCT GGAGGGAATG 1440

CTAGAGGGAG CATCCCATCT TCGTCCTGCT CTTCATGTCA TCAGTAACTT GTTAGGAACT 1500

TGCTGTGACT CTGACCTGCT CTGCTCCTTC TGCAATGACA TAGGACTGCC CCAGTTTCTC 1560

ATGCAACTAG TGGAGAGCAT CCTGAAGAGC TTCAACATCA AACAGCAGCC CTGGCACATC 1620

ACTCTACTGA CTGACTTAAT GGCTGTGATG ACCGTTTTCT TTGCCAGTGA TTTCAACCGA 1680

GAGAAAGATG GAAAAAAGCA AAGTTTGCAG GCATTCCAGA GCTCTGCTAA TCACTTCCTC 1740

ACTCTGTTAC CAGCATTGCT GGCTCAGCCC ACAGATCAAG AGGGCAGGCT GCGGGAACAA 1800

AGCCTTGTGT GCTTCACTCA TTTGTGTCAG AGTATGGATA ATGCCTGCCC TTCCATCTCC 1860

ATCCCCTTCT ATACCAGCTT GCTTGAGAAC CATTGCCCTC TGCTGGACAC ACTCTGCCAT 1920

GGTGTCAGTT GTGAGCAAAT CATCCAGGAA GTGCCCCCCA AAGAAGCAAG GTCAAAGCAG 1980

CACTGGAATG AGCTCATGGG AGCTGCCTTT GCAAAAGCCC TGGCTGCATC TTGTGTCATC 2040

CCTGGAAGGC ACACCGTTTG TCAAAAGGCA AAAAAGAAGA TCTCCCAGTA CATAGCTGAG 2100

AAGCTCACTG AGAAAGAGAA CCGGCTGTTG GCAAGCTTAA TCTTAGCAGT TAATCATCCA 2160

GCCTCTTCTT TGCATGGCCT AAAGGTCCTG TATGCCTGTG GCCATGTCAG TCAGACTCTC 2220

TGCCATCATT TAGCAACACC TGAAATGCTA AACTCCCTGA TTTGTCACCT TCAAGGCAAG 2280

GTATTCATTC ATTCATATGT GCAGACTGCT GAAGCCTCAT TGAGACTCTT CTCCTTGCTG 2340

ATGCTTCAGC TCCAGTTTCT CCCATCACAA TCTGATATTG TGCTGAATGA GACTATGAAG 2400

CTTTTCAACT CTGGAGCAAC TGCCTCTGTT TTAAGTGCTG CCGCATTGCT ACTTACATAT 2460

TTCATTCAGC ATGGCGCTGC TGTGAAGCTC AGGTGGGAGG AAGCCTTGAC AGCTATAGCT 2520

ACTGCATTCA CAGAATCTGC GGAGCCCTGC CTGCCACCTC CTATGGGAGT TGGCTTCTAC 2580

GATGGCCTGC TGATCTTACT ACTGCATGTG TTAAGTGAGC AGGGGGATGT AGCAATGGTG 2640

CGGGAATTTG CTGCTTCGGA GCTCTGGGGC ATCGTGTGGC ATCTTTTTGC TATGGTGCTC 2700

CACATGACCA CTCAAGAGCC AATGCTAGAA GGAGAGACTT CTGGAGCTGG CCAACATGCA 2760

CCAGAGCCAG ACTGGGACCT CATTTCACCT CAAGGAACCC CGTTCTTCCT CAGCTTAACA 2820

CTCTTTGTCT TCACATGTGA GCCCCACCAG TGTCTTCTCC AGATGGCCCA GCCCAATGGG 2880

CTTATCATGG CAGTTTTGAA CAAGCTGCTG GACCCAGATT TCCTAGAGTG CTTGGCCCAA 2940

ATGCAGTTGC ACGAGGATGG TGATTTAGAG TTAGTGACAA CTACTGTGCT CCAAGTCTGC 3000

CAAGTCTTTT GTTTCGCATT TGCTATGGAT ATGGACCCTG AAATTTTAGA ACAAATTCTG 3060

ACTAATATGA AGGGCTCTGA AATCCCTGCC CAGTTGTTAC AGGTTTGCAT TCACCATCTT 3120

CCTTGTACGA AAACTGAGCT GCCATTGAGT CTGCTCTGCC GCTTGGTGCT GAGTGATGAG 3180

GAGATCATTG AGCAGGTGGT GGGAGCAGCC ACCTCACAAG ATGCCATTGA TTTCTTGTCA 3240

TCTATTTTCC TATCAGACCA AGTACACCTA CTTGCAGACT TGCTCACCCT CCTCACACAT 3300

ATAGCCCGGG CCAGTCCATC TCACCTGCCT TTTCTAGAGA AACTTCTCTC TGGCTCCACC 3360

TCCCAGGCAC TGAGCCATCT TCTGGGCCAT TCGGAGTGCC TGGTCCGTGC CAGAACCTGC 3420

AGCCTTGTGG GCAATCTTCT GCGCCATGGA CAGGAATTTC CTCACATTCT ACAGGGTCAG 3480

GTTGGGCTGC TGAAATCTCT GCTGGAACGA CTTTCAGATG AAGATAGACA TGTGCGTCGC 3540

TCTGCCAGTT TTGCTGTTGG CAATGCAGCC TACCAAGCTG GCCCTTTTAT GCAGGACCTC 3600

AGAAAAGCAG TGCCTTGTGT AGTTCGGCTC CTGGGTGATC CTCAAGCAAA GACCCGTTGC 3660

AATGCGGCTT CAGCGCTGGG TAACCTGGGT TGGCAGTCGG TGGAACTGGG GGATTCACTG 3720

ATACAGAATA AAGCACCCAA TATTCTGCTG GATGTTGCCT GCCATGATTC CCAGCCAGCT 3780

GTACAAAAGG CTGCCCTAAT TGCTCTCCGC TCCATGAGCC ATCAGCCCAG GATTCGCCAG 3840

GTGCTGGTAT CACTCAGGGC ATGTGAGAAG TTGGAAGCAC TTACCCTTGA CCAGTTTCAG 3900

AATAGTGCCT ATAGCCACCC TTGGCCTTCA TCAACACAGC ACTGCAAAAA ATTGATCCAA 3960

CTTCTGCAAC CGTCCCAAAG TGCTTGA 3987

Domain Profile

S: 1     ysleeeiGkGsfavvykgrlrkktsqvvAikvvekkkl.kkslenlekeikilkelkhen  59

         y++ e+iG+Gsf+ vykgr rk t++ vA+k++ k ++ +k+l+nl++ei+i++ l+h+n

Q: 4     YHVLEMIGEGSFGRVYKGR-RKYTTKIVALKFIPKVGRsQKELKNLQREIEIMRGLHHPN  62

         8999***************.******************9*********************

S: 60    ivalldveetskevylvmeycaggdLakllkqkkeLsedtvreflqqlasalkaLhskki  119

         iv++ld++et+kev++v++y++ g+L ++l+++++L+e++v+ +++ql+sal++Lhs++i

Q: 63    IVQMLDSFETDKEVVVVTDYAE-GELFQILEDDGNLPEEQVQIIASQLVSALYYLHSHRI  121

         **********************.*************************************

S: 120   vhrDlkPqniLlsyadakkelkkvtlkladFglarvlkeesma.atlkGsplYmaPEvvk  178

         +hrD+kPqniLl         k + +kl+dFg+ar+++ ++m  +++kG+plYm+PE+v+

Q: 122   LHRDMKPQNILLG--------KGGVIKLCDFGFARAMSIHTMVlTSIKGTPLYMSPELVE  173

         *************........89*******************99****************

S: 179   eqqydakaDlWSiGtilyellvGkpPfaaesiseLvekiekndvleppipkeisselkdl  238

         e+ yd++aDlWS+G+ilyel vG+pPf+++si++Lv+ i k++v   ++pk++s ++k++

Q: 174   EKPYDHTADLWSVGCILYELYVGTPPFYTNSIFQLVSLIIKDPV---KWPKNMSLHFKSF  230

         ********************************************...*************

S: 239   lqsLLqrdpkkRisfeelfahpfl  262

         lq+LL ++p++R+s+ el+ hpf+

Q: 231   LQGLLMKNPHERLSWPELLYHPFI  254

         **********************96

Domain Sequence
(FASTA)

YHVLEMIGEG SFGRVYKGRR KYTTKIVALK FIPKVGRSQK ELKNLQREIE IMRGLHHPNI 60

VQMLDSFETD KEVVVVTDYA EGELFQILED DGNLPEEQVQ IIASQLVSAL YYLHSHRILH 120

RDMKPQNILL GKGGVIKLCD FGFARAMSIH TMVLTSIKGT PLYMSPELVE EKPYDHTADL 180

WSVGCILYEL YVGTPPFYTN SIFQLVSLII KDPVKWPKNM SLHFKSFLQG LLMKNPHERL 240

SWPELLYHPF I 251

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013