EKS-ANC-00071

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00071

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/GSK	442.4	6.4E-133	25	308	284

Status

Unreviewed

Ensembl Protein

ENSACAP00000003180

UniProt Accession

H9G7A2;

Protein Name

Protein Synonyms/Alias

Gene Name

GSK3A

Gene Synonyms/Alias

GSK3A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000003202	ENSACAP00000003180	ENSACAT00000003261

Organism

Anolis carolinensis

Functional Description

Protein Length

366

Protein Sequence
(FASTA)

DSGKVTTVVA TPGQGPDRPQ EVSYSDIKVI GNGSFGVVYQ ARLADSGELV AIKKVLQDKR 60

FKNRELQIMR KLDHCNIVRL RYFFYSSGEK KDEVYLNLVL DFVPETVYRV ARHFTKAKQT 120

IPVIYVKVYM YQLFRSLAYI HSQGVCHRDI KPQNLLVDPD TAVLKLCDFG SAKQLVRGEP 180

NVSYICSRYY RAPELIFGAT DYTSNIDIWS AGCVLAELLL GQPIFPGDSG VDQLVEIIKV 240

LGTPTREQIR EMNPNYTEFK FPQIKAHPWI KVFKPRTPLE AISLCSRLLE YTPATRLSPL 300

EACANSFFDE LREPNARLPN GRELPPLFNF SPVELSIQPG LNSNLIPPHI RSQATSVGTG 360

SGSTTA 366

Nucleotide Sequence
(FASTA)

GACAGTGGGA AGGTGACCAC GGTGGTCGCC ACGCCAGGCC AAGGGCCGGA CCGCCCGCAG 60

GAGGTCTCCT ACTCGGACAT CAAGGTCATC GGCAACGGCT CCTTCGGGGT GGTGTACCAG 120

GCCCGCCTGG CCGACTCGGG GGAGCTGGTG GCCATCAAGA AGGTGCTGCA GGACAAGCGC 180

TTTAAGAACC GGGAGCTGCA GATCATGCGG AAGCTGGACC ACTGCAACAT TGTGCGCTTG 240

CGGTATTTCT TCTACTCCAG TGGGGAAAAG AAGGATGAGG TTTACCTCAA TTTAGTCCTG 300

GACTTTGTGC CAGAGACCGT GTACCGCGTG GCCCGGCACT TCACCAAAGC CAAGCAGACC 360

ATCCCTGTCA TCTACGTGAA GGTGTACATG TACCAGCTAT TCCGCAGCCT CGCTTACATC 420

CATTCTCAAG GTGTCTGTCA TCGGGACATC AAACCCCAGA ACCTCCTGGT GGACCCCGAC 480

ACGGCCGTAC TGAAGCTTTG TGACTTCGGC AGCGCAAAGC AGCTGGTGCG GGGAGAGCCC 540

AACGTCTCCT ACATCTGCTC CCGCTACTAC CGGGCCCCTG AGCTCATCTT TGGAGCCACC 600

GATTACACCT CCAACATCGA TATCTGGTCG GCCGGCTGTG TCCTGGCAGA ACTGCTCCTG 660

GGCCAGCCTA TATTTCCTGG TGACAGTGGT GTGGACCAGC TAGTGGAGAT CATCAAGGTG 720

CTGGGGACGC CGACGCGAGA ACAGATCCGA GAGATGAACC CCAACTACAC AGAGTTCAAG 780

TTCCCCCAGA TCAAAGCACA CCCCTGGATC AAGGTGTTCA AACCCCGCAC GCCGCTGGAG 840

GCCATTTCGC TGTGCAGCCG GCTGCTGGAG TACACACCGG CCACCCGCCT CTCCCCACTG 900

GAGGCCTGCG CCAACAGCTT CTTTGATGAG CTGCGAGAGC CCAACGCCCG GCTACCCAAC 960

GGCCGCGAGC TGCCCCCACT CTTCAACTTC AGCCCTGTGG AGCTGTCCAT CCAGCCAGGC 1020

CTGAATTCTA ACCTCATTCC GCCACACATC CGGTCCCAGG CCACTTCTGT GGGAACAGGG 1080

TCTGGTTCCA CAACCGCA 1098

Domain Profile

S: 2     eelkligsGsFgnVyqavlseesekevaiKkvlqdkklknlEleilrklkHknivrLlyf  61

         +++k+ig+GsFg+Vyqa+l+++ e  vaiKkvlqdk++kn+El+i+rkl+H+nivrL+yf

Q: 25    SDIKVIGNGSFGVVYQARLADSGEL-VAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYF  83

         6899*********************.**********************************

S: 62    fsksaekkdkvylnlvleylPetlakvlrelkdkkkkldvlevklytyQlfrglaylhsl  121

         f++s ekkd+vylnlvl+++Pet+++v+r+++++k++++v++vk+y+yQlfr+lay+hs+

Q: 84    FYSSGEKKDEVYLNLVLDFVPETVYRVARHFTKAKQTIPVIYVKVYMYQLFRSLAYIHSQ  143

         ************************************************************

S: 122   eivHrDiKPqNllvdeetgvlKlcDfGsakrleknepnvsYivsRyYRaPELllgakeyt  181

         +++HrDiKPqNllvd++t+vlKlcDfGsak+l+++epnvsYi+sRyYRaPEL++ga++yt

Q: 144   GVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYT  203

         ************************************************************

S: 182   tkiDvWsagcvlaEllkgkvlfkgksakdqlelivkvlGtptkedikemnvkykekkfkk  241

         ++iD+WsagcvlaEll+g+++f+g+s++dql++i+kvlGtpt+e+i+emn++y+e+kf++

Q: 204   SNIDIWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQ  263

         ************************************************************

S: 242   ikkvslakvlkkkedkeavdllkkilkyepkkRlsalellahpff  286

         ik++++ kv+k +++ ea+ l++++l+y+p++Rls+le++a++ff

Q: 264   IKAHPWIKVFKPRTPLEAISLCSRLLEYTPATRLSPLEACANSFF  308

         ********************************************9

Domain Sequence
(FASTA)

SDIKVIGNGS FGVVYQARLA DSGELVAIKK VLQDKRFKNR ELQIMRKLDH CNIVRLRYFF 60

YSSGEKKDEV YLNLVLDFVP ETVYRVARHF TKAKQTIPVI YVKVYMYQLF RSLAYIHSQG 120

VCHRDIKPQN LLVDPDTAVL KLCDFGSAKQ LVRGEPNVSY ICSRYYRAPE LIFGATDYTS 180

NIDIWSAGCV LAELLLGQPI FPGDSGVDQL VEIIKVLGTP TREQIREMNP NYTEFKFPQI 240

KAHPWIKVFK PRTPLEAISL CSRLLEYTPA TRLSPLEACA NSFF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013