EKS-ANC-00270

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00270

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	421.5	1.5E-126	174	461	288

Status

Unreviewed

Ensembl Protein

ENSACAP00000003417

UniProt Accession

H9G7M4;

Protein Name

Protein Synonyms/Alias

Gene Name

ACVR2A

Gene Synonyms/Alias

ACVR2A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000003484	ENSACAP00000003417	ENSACAT00000003501

Organism

Anolis carolinensis

Functional Description

Protein Length

495

Protein Sequence
(FASTA)

GAILGRSETQ ECIFYNANWE NDRTNRSGIE SCYGDKDKRR HCFATWKNIS GSIEIVKKGC 60

WLDDINCYDR AECIERKDSP EVFFCCCEGN MCNEHFFYSP EMEVTQPTSN PVPPKQPLFS 120

TLLYSLVPIM GIAVIILFSF WMYRHHKLAY PPVLVPTQDP GPPPPSPLMG LKPLQLLEVK 180

ARGRFGCVWK AQLLNEYVAV KIFPIQDKQS WQNEYEVYSL PGMKHENILQ FIGAEKRGTN 240

IDVDLWLITA FHEKGSLTDF LKANVVSWNE LCHIAETMAR GLAYLHEDIP GLKDGHKPAI 300

SHRDIKSKNV LLKNNLTACI ADFGLALKFE AGKSAGDTHG QVGTRRYMAP EVLEGAINFQ 360

RDAFLRIDMY AMGLVLWELA SRCTASDGPV DEYMLPFEEE VGQHPSLEDM QEVVVHKKKR 420

PVLRECWQKH AGMAMLCETI EECWDHDAEA RLSAGCVEER IIQMQRLTNI ITTEDIVTVV 480

TMVTNVDFPP KESSL 495

Nucleotide Sequence
(FASTA)

GGTGCCATTC TAGGCAGATC AGAGACACAG GAGTGCATCT TCTACAACGC TAATTGGGAA 60

AATGATAGAA CAAATCGCAG TGGCATTGAA TCGTGTTATG GTGATAAAGA TAAAAGACGA 120

CATTGCTTTG CAACGTGGAA GAATATTTCT GGATCTATTG AAATTGTGAA AAAGGGTTGC 180

TGGCTGGATG ATATTAACTG TTATGACAGA GCTGAATGCA TAGAAAGGAA AGACAGCCCT 240

GAAGTATTTT TCTGCTGCTG TGAAGGCAAC ATGTGCAATG AACATTTTTT CTACTCTCCA 300

GAGATGGAGG TCACACAGCC TACTTCCAAT CCTGTTCCAC CTAAACAACC CTTGTTCAGT 360

ACTTTACTTT ATTCTCTTGT GCCTATAATG GGAATTGCAG TTATCATACT GTTTTCATTT 420

TGGATGTACC GACACCATAA ATTGGCATAT CCTCCAGTAC TTGTACCAAC CCAGGATCCT 480

GGACCACCTC CTCCATCACC TCTGATGGGC CTCAAGCCAC TGCAGTTACT TGAGGTCAAA 540

GCCAGGGGGA GATTTGGCTG TGTCTGGAAA GCTCAGTTGT TAAATGAATA TGTGGCTGTG 600

AAAATATTCC CCATCCAGGA CAAACAATCA TGGCAAAATG AATATGAGGT ATATAGTTTG 660

CCTGGAATGA AGCATGAAAA TATTCTACAG TTTATTGGTG CTGAGAAACG AGGAACCAAC 720

ATTGATGTTG ATTTGTGGCT GATAACAGCA TTTCATGAAA AGGGGTCACT TACTGATTTT 780

CTGAAAGCTA ATGTAGTCTC ATGGAATGAA CTCTGTCACA TCGCTGAAAC TATGGCTAGG 840

GGTTTGGCTT ACCTTCATGA AGATATCCCT GGTCTGAAAG ATGGACATAA ACCAGCTATA 900

TCCCACAGGG ACATTAAAAG CAAGAATGTA TTGCTGAAAA ATAATCTTAC GGCTTGTATT 960

GCTGACTTTG GCCTTGCTTT AAAATTTGAG GCTGGGAAGT CAGCAGGCGA TACACATGGT 1020

CAGGTTGGCA CCCGAAGATA CATGGCTCCC GAAGTGTTAG AAGGTGCTAT CAACTTCCAA 1080

AGGGATGCAT TTTTGAGAAT AGATATGTAT GCCATGGGAC TAGTCTTGTG GGAACTGGCA 1140

TCACGATGTA CTGCATCAGA TGGGCCAGTG GATGAATATA TGTTACCTTT TGAGGAAGAA 1200

GTGGGCCAGC ATCCTTCTCT TGAAGATATG CAGGAAGTTG TTGTACATAA AAAGAAGAGG 1260

CCTGTCTTGA GGGAGTGTTG GCAGAAACAT GCTGGAATGG CAATGCTCTG TGAAACAATA 1320

GAAGAGTGTT GGGATCATGA TGCAGAAGCT CGATTGTCAG CAGGCTGTGT AGAGGAACGC 1380

ATTATTCAGA TGCAAAGACT CACAAACATT ATAACAACAG AGGACATTGT GACAGTGGTC 1440

ACGATGGTGA CAAATGTGGA CTTCCCTCCC AAAGAATCCA GTCTATGA 1488

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         l+lle+ ++Gr+g+Vwka+l +e+vAvKif+ +d++sw++E e+y+++ ++henilqfi+

Q: 174   LQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIG  233

         6899********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         a+k+ ++  ++l+l+t++hekgsL+d+Lk+++++++el+++a+++a+Gla+LHe+i+g k

Q: 234   AEKRGTNIDVDLWLITAFHEKGSLTDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLK  293

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         + +Kpai+HRD+kskN+l+k++lt+ciaD+GLalk+e+ k++ d  ++ qvGt+RYmaPE

Q: 294   DGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGD--THGQVGTRRYMAPE  351

         *****************************************888..79************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vle+a+n+++ +af r+D+Y++gLvlWE+asRc+++d+ v+ey+lpfee+vg++Psle+m

Q: 352   VLEGAINFQR-DAFLRIDMYAMGLVLWELASRCTASDGPVDEYMLPFEEEVGQHPSLEDM  410

         *********9.9************************************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         +evvv+kk+rP ++e w+k++ +++l++++eecWd+d+eaRl+a +v++r+

Q: 411   QEVVVHKKKRPVLRECWQKHAGMAMLCETIEECWDHDAEARLSAGCVEERI  461

         ************************************************985

Domain Sequence
(FASTA)

LQLLEVKARG RFGCVWKAQL LNEYVAVKIF PIQDKQSWQN EYEVYSLPGM KHENILQFIG 60

AEKRGTNIDV DLWLITAFHE KGSLTDFLKA NVVSWNELCH IAETMARGLA YLHEDIPGLK 120

DGHKPAISHR DIKSKNVLLK NNLTACIADF GLALKFEAGK SAGDTHGQVG TRRYMAPEVL 180

EGAINFQRDA FLRIDMYAMG LVLWELASRC TASDGPVDEY MLPFEEEVGQ HPSLEDMQEV 240

VVHKKKRPVL RECWQKHAGM AMLCETIEEC WDHDAEARLS AGCVEERI 288

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0017002	; F:activin-activated receptor activity
GO:0005524	; F:ATP binding
GO:0004702	; F:receptor signaling protein serine/threonine kinase activity
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0023014	; P:signal transduction by phosphorylation

KEGG

InterPros

IPR000333	; Activin_II/TGFBeta-II_recpt.
IPR015768	; Activin_II_recpt.
IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00653

; ACTIVIN2R.

Created Date

20-Feb-2013