EKS-ANC-00273

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00273

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	381.0	3.3E-114	210	508	299

Status

Unreviewed

Ensembl Protein

ENSACAP00000004815

UniProt Accession

H9G9P4;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR2

Gene Synonyms/Alias

BMPR2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000004885	ENSACAP00000004815	ENSACAT00000004923

Organism

Anolis carolinensis

Functional Description

Protein Length

1045

Protein Sequence
(FASTA)

ITCTLNWAWN VIGSQWSCLN RGVDVSLLAA QSEETTCAFR DVYQNDHGIS ENRISQENGT 60

ILCMKGSTCY GLWEKTREGE IHLVKQGCWS HIGDPQECHS EECIVTTTPS LVQNGTYRFC 120

CCSTNLCNVN FTENFPPPDP IDATSPPSPH KFRRSETIVI VLASVSVLAV LVVALFFGYR 180

MFVGDRKQGL HSMDMMEAAA SEPSLDLDNL KLLELIGRGR YGAVYKGSLD ERPVAVKVFS 240

FTNRQNFINE RNIYRIPLME HDNIAHFIVG DERFTADGRM EYLLVMEYYA NGSLCRYLSL 300

HTSDWVSSCR LAHSITRGLA YLHTELPRGD CYKPAISHRD LNSRNVLVKN DGTCVISDFG 360

LSMKLTGNRL VRPGEEDNAA ISEVGTIRYM APEVLEGAVN LRDCESALKQ VDMYALGLIY 420

WEIFMRCTDL FPGESVPEFQ TAFQTEVGNH PTFEDMQVLV SREKQRPKFP EAWKENSLAV 480

RSLKETIEDC WDQDAEARLT AQCAEERMAE LMMIWERNRS VSPTVNPMST AMQNERNLSH 540

HRRVPKIRPY QDYSSSSYIE DSIHHNDSIV KNISSELSLS STPLTLGEKN RNSINYERQQ 600

AQARIPSPET SVTSLSTNTT TTNTTGLTPS TGMTTISEMP HSGDISVSAG NGVGPTPGCL 660

QLTEEDLETN KLDPKEVDKN LKESSDENLM EHSLKQFSGP DPLSSTSSSL LYPLIKLAVE 720

ATGQPDFTQT GNGQACLIPD VQPAQVYPLP KQQNLPKRPT TLPLNTKNST KEPRLKFGGK 780

HKSNLKQVET GVAKMNTVSA AEPHVVTVTT NEVAGRSHTI NSHAVPTQYV NGTVPSSQST 840

SSGVHRAQEM LQNQFSGEDS RLNINSSPDE HEPLLRREQQ VSHDEGVLER LVDRRERSLD 900

NGRTNANNNN NSSSNSCPGQ GVCTLVNMRT APNSEQTRTK RAQRPNSLDL SATNILDSCS 960

MQLSESSLDS KPGSGEKIKK RVKTPYSLKR WRPSTWVIST EPLDCEVNNN GGDRVVSSKS 1020

SIAVYLVDGG TATTMVSKDA GVDCL 1045

Nucleotide Sequence
(FASTA)

ATAACCTGCA CCTTAAATTG GGCCTGGAAT GTAATCGGCA GCCAGTGGAG CTGCTTGAAC 60

AGGGGGGTTG ACGTCTCCCT TTTAGCTGCC CAAAGCGAAG AGACAACATG TGCTTTTCGG 120

GATGTTTACC AAAATGACCA TGGGATTAGT GAAAATCGAA TTTCTCAGGA GAATGGTACA 180

ATCTTGTGCA TGAAAGGCAG CACCTGCTAT GGTCTTTGGG AGAAAACGCG AGAAGGAGAA 240

ATACATCTTG TGAAACAAGG ATGTTGGTCT CATATAGGAG ATCCCCAAGA GTGCCATTCT 300

GAGGAATGCA TAGTAACAAC AACACCTTCC TTGGTTCAGA ATGGGACATA CCGCTTCTGC 360

TGCTGCAGTA CCAACCTATG CAATGTCAAC TTCACAGAGA ACTTTCCACC CCCAGATCCG 420

ATAGATGCAA CATCACCACC CTCCCCACAT AAATTTAGAA GATCAGAAAC AATTGTCATC 480

GTTCTGGCAT CAGTGTCAGT ACTGGCTGTT TTGGTGGTTG CTCTTTTCTT TGGATACAGG 540

ATGTTTGTAG GGGATCGTAA ACAAGGTCTG CACAGTATGG ATATGATGGA AGCAGCAGCA 600

TCAGAACCCT CGCTAGACCT GGATAATTTG AAGCTGCTGG AGCTGATTGG TCGAGGGCGA 660

TATGGAGCAG TCTACAAAGG TTCCTTAGAT GAGCGTCCAG TGGCTGTAAA AGTGTTTTCT 720

TTCACTAATC GTCAAAATTT TATCAATGAG AGAAATATAT ACAGAATACC ACTAATGGAA 780

CATGACAACA TTGCCCACTT CATTGTTGGA GATGAGAGAT TCACTGCAGA TGGACGGATG 840

GAGTATTTAT TAGTGATGGA ATATTATGCC AATGGGTCCT TGTGCAGATA TTTGAGTCTT 900

CATACTAGCG ACTGGGTGAG CTCCTGTCGG TTAGCACACT CTATAACTCG AGGCTTGGCA 960

TATCTTCATA CAGAGTTGCC ACGAGGAGAT TGCTATAAAC CTGCCATCTC CCATCGTGAT 1020

CTGAACAGTC GCAATGTATT GGTGAAGAAT GATGGGACAT GTGTCATCAG TGATTTTGGT 1080

CTCTCCATGA AGCTAACAGG AAATAGACTT GTTCGTCCAG GGGAGGAGGA CAATGCTGCC 1140

ATTAGTGAGG TTGGTACAAT CCGTTATATG GCTCCTGAAG TGTTGGAAGG AGCAGTGAAC 1200

TTGAGAGACT GTGAATCAGC TCTGAAGCAA GTAGATATGT ATGCACTAGG TCTAATCTAC 1260

TGGGAGATTT TTATGAGATG CACAGACTTG TTCCCAGGAG AATCAGTGCC AGAGTTCCAG 1320

ACAGCTTTCC AAACAGAAGT TGGAAACCAC CCTACTTTTG AAGATATGCA AGTCCTTGTT 1380

TCAAGGGAAA AGCAAAGACC AAAATTCCCA GAGGCCTGGA AAGAGAACAG CTTGGCTGTG 1440

AGATCGCTGA AAGAGACAAT AGAAGACTGT TGGGATCAGG ACGCTGAAGC TCGACTGACT 1500

GCCCAGTGTG CAGAAGAAAG GATGGCTGAA CTTATGATGA TTTGGGAGAG GAATAGATCT 1560

GTTAGCCCGA CAGTTAACCC TATGTCTACA GCTATGCAAA ATGAGCGAAA CTTGTCACAC 1620

CATAGGCGTG TGCCAAAGAT CAGACCATAT CAAGATTATT CTTCTTCATC TTACATTGAG 1680

GACTCAATTC ACCACAATGA TAGCATAGTG AAGAACATTT CCTCTGAACT TTCTTTGTCA 1740

AGCACACCAC TGACACTTGG GGAGAAGAAC AGAAACTCAA TTAACTATGA GCGGCAGCAA 1800

GCACAAGCCC GTATTCCTAG TCCCGAGACA AGTGTCACAA GTTTGTCCAC CAACACAACC 1860

ACCACCAACA CAACAGGCCT CACTCCAAGC ACTGGCATGA CCACCATATC CGAAATGCCC 1920

CACTCAGGTG ACATAAGCGT CAGTGCAGGA AATGGTGTTG GGCCGACCCC TGGTTGTCTA 1980

CAGCTGACAG AGGAGGACTT GGAGACCAAT AAATTGGATC CAAAGGAAGT GGATAAGAAC 2040

CTGAAAGAAA GCTCTGATGA GAACCTGATG GAGCATTCCC TTAAGCAGTT CAGTGGCCCA 2100

GATCCACTCA GCAGCACCAG CTCCAGCTTG CTCTATCCAT TGATAAAGCT TGCAGTAGAA 2160

GCAACAGGGC AACCAGACTT CACACAAACT GGAAATGGTC AAGCCTGCCT AATTCCAGAT 2220

GTTCAGCCTG CTCAGGTGTA TCCTCTTCCC AAGCAACAGA ATCTCCCAAA GAGGCCTACC 2280

ACCCTACCCT TAAACACCAA AAACTCCACA AAGGAGCCTC GGCTGAAATT CGGAGGGAAG 2340

CACAAATCAA ACTTGAAGCA AGTAGAAACA GGAGTTGCCA AGATGAACAC TGTCAGTGCT 2400

GCAGAACCTC ATGTGGTAAC AGTGACCACA AATGAAGTGG CAGGAAGAAG TCATACCATT 2460

AACTCTCATG CTGTGCCAAC CCAGTATGTC AATGGTACAG TGCCATCTAG CCAATCAACC 2520

AGCTCAGGAG TACACAGGGC CCAGGAAATG CTGCAGAACC AATTCAGTGG AGAGGACAGC 2580

CGTCTGAATA TCAACTCAAG CCCTGATGAG CATGAGCCCT TATTAAGGCG GGAGCAGCAA 2640

GTGAGCCATG ATGAGGGTGT TCTGGAACGT CTGGTTGATC GGAGAGAGCG CTCGCTGGAT 2700

AATGGCCGAA CAAATGCCAA CAACAACAAC AATAGCAGCA GCAACTCATG TCCAGGACAA 2760

GGTGTCTGTA CTCTCGTCAA TATGAGAACA GCACCAAATT CTGAACAGAC CCGTACTAAA 2820

AGAGCACAGA GGCCTAACTC CCTGGATTTA TCAGCCACAA ATATTTTAGA CAGCTGTAGC 2880

ATGCAGTTGA GCGAGTCATC CCTTGATAGC AAACCGGGCT CAGGAGAAAA GATCAAAAAA 2940

CGTGTGAAAA CACCTTATTC TCTTAAGCGG TGGCGTCCTT CCACATGGGT CATCTCCACA 3000

GAACCACTGG ACTGTGAAGT CAACAACAAT GGTGGTGATA GGGTGGTTAG TTCTAAGTCC 3060

AGCATAGCTG TTTACCTTGT AGATGGAGGT ACTGCCACAA CTATGGTGTC TAAGGATGCA 3120

GGAGTGGACT GTCTGTGA 3138

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         lkllelig+Gryg+V+k++l+++ vAvK+fs ++++++ +E++iy+ +l++h+ni +fi+

Q: 210   LKLLELIGRGRYGAVYKGSLDERPVAVKVFSFTNRQNFINERNIYRIPLMEHDNIAHFIV  269

         6899********************************************************

S: 61    adk.keedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgt  119

          d+  ++d ++e+llv+ey+ +gsL+ yL+ +t+d+ +++rla+s+++Gla+LH+e++

Q: 270   GDErFTADGRMEYLLVMEYYANGSLCRYLSLHTSDWVSSCRLAHSITRGLAYLHTELPRG  329

         **98999*************************************************9765

S: 120   kgkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekee....ldlaansqvGtkR  175

          + +Kpai+HRDl+s+N+lvk+d+tc+i+D+GL++kl+ ++ +    +d+aa+s+vGt R

Q: 330   -DCYKPAISHRDLNSRNVLVKNDGTCVISDFGLSMKLTGNRLVrpgeEDNAAISEVGTIR  388

         .479*********************************9999877787999**********

S: 176   YmaPEvleealnlkdfe.afkraDvYslgLvlWEvasRcee..vdeeveeyklpfeevvg  232

         YmaPEvle+a+nl+d+e a+k++D+Y+lgL++WE+++Rc++  ++e+v+e++ +f+++vg

Q: 389   YMAPEVLEGAVNLRDCEsALKQVDMYALGLIYWEIFMRCTDlfPGESVPEFQTAFQTEVG  448

         *****************99*****************************************

S: 233   sdPsleemkevvvekklrPkipeawkkke.alkelsklleecWdadpeaRltalrvkkrl  291

         ++P++e+m+ +v ++k+rPk+peawk+++ a+++l++++e+cWd+d+eaRlta++ ++r+

Q: 449   NHPTFEDMQVLVSREKQRPKFPEAWKENSlAVRSLKETIEDCWDQDAEARLTAQCAEERM  508

         ***************************9999*************************9987

Domain Sequence
(FASTA)

LKLLELIGRG RYGAVYKGSL DERPVAVKVF SFTNRQNFIN ERNIYRIPLM EHDNIAHFIV 60

GDERFTADGR MEYLLVMEYY ANGSLCRYLS LHTSDWVSSC RLAHSITRGL AYLHTELPRG 120

DCYKPAISHR DLNSRNVLVK NDGTCVISDF GLSMKLTGNR LVRPGEEDNA AISEVGTIRY 180

MAPEVLEGAV NLRDCESALK QVDMYALGLI YWEIFMRCTD LFPGESVPEF QTAFQTEVGN 240

HPTFEDMQVL VSREKQRPKF PEAWKENSLA VRSLKETIED CWDQDAEARL TAQCAEERM 299

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR015770	; BMPRII.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013