EKS-ANC-00240

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00240

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	317.4	5.3E-95	3	237	235

Status

Unreviewed

Ensembl Protein

ENSACAP00000006688

UniProt Accession

G1KFT1;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKAA2

Gene Synonyms/Alias

PRKAA2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000006771	ENSACAP00000006688	ENSACAT00000006834

Organism

Anolis carolinensis

Functional Description

Protein Length

519

Protein Sequence
(FASTA)

VGEHQLTGHK VAVKILNRQK IRSLDVVGKI KREIQNLKLF RHPHIIKLYQ VISTPTDFFM 60

VMEYVSGGEL FDYICKHGRV EETEARRLFQ QILSAVDYCH RHMVVHRDLK PENVLLDAHM 120

NAKIADFGLS NMMSDGEFLR TSCGSPNYAA PEVISGRLYA GPEVDIWSCG VILYALLCGT 180

LPFDDDHVPT LFKKIRGGVF YIPEYLNRSV ATLLMHMLQV DPLKRATIKD MREHEWFKQD 240

LPNYLFPEDP SYDANVIDDD AVREVCEKFE CTESEVMASL YSGDPQDQLA VAYHLIIDNR 300

RIMNQASEFY LASSPPSGSF MDDSMHIPPG VKPHPERMPP LVADSPKAKC PLDALNTTKP 360

KPLTVKKAKW HLGIRSQSKP YDIMAEVYRA MKQLEFEWKV VNAYHLRVRR KNPVTGNFVK 420

MSLQLYQVDN RSYLLDFKSI DDDVMEQRSG SSTPQRSCSA ARLHRPRLSF DSASADYQPL 480

SGSLSGSFTG SMPSVTPRLG SHTMDFFEMC ASLIMALAR 519

Nucleotide Sequence
(FASTA)

GTTGGTGAAC ATCAGCTCAC AGGACATAAA GTAGCAGTCA AAATTTTGAA TAGGCAAAAA 60

ATCCGCAGTT TGGATGTGGT TGGAAAGATC AAACGAGAAA TTCAAAACTT AAAGCTTTTC 120

CGGCACCCCC ATATTATCAA ACTGTACCAG GTCATCAGCA CGCCAACGGA TTTTTTCATG 180

GTAATGGAAT ATGTGTCCGG TGGGGAATTA TTTGATTACA TCTGTAAACA CGGACGGGTG 240

GAAGAGACTG AAGCCAGACG TCTTTTCCAG CAAATTCTGT CAGCTGTAGA TTACTGTCAT 300

CGGCACATGG TGGTTCATAG AGATTTGAAA CCAGAGAATG TGCTGTTGGA TGCACACATG 360

AATGCCAAGA TAGCTGATTT TGGGTTGTCC AACATGATGT CTGATGGTGA ATTTCTCCGA 420

ACCAGCTGTG GCTCACCCAA CTATGCAGCA CCAGAAGTCA TCTCTGGAAG GTTGTATGCT 480

GGTCCAGAGG TTGATATTTG GAGCTGTGGC GTTATTCTTT ATGCTCTTCT CTGTGGGACT 540

CTTCCTTTTG ATGACGACCA TGTCCCAACA CTCTTTAAAA AAATCCGTGG AGGTGTCTTC 600

TACATTCCTG AATACCTTAA CCGCTCAGTT GCTACTCTAC TGATGCATAT GTTGCAGGTT 660

GACCCACTCA AAAGAGCAAC CATAAAGGAT ATGCGAGAAC ATGAGTGGTT CAAGCAGGAT 720

CTGCCCAATT ACTTGTTTCC TGAAGACCCT TCCTATGATG CCAATGTCAT TGATGATGAT 780

GCTGTGCGGG AGGTTTGTGA GAAATTTGAA TGCACTGAAT CAGAGGTGAT GGCAAGCCTA 840

TACAGTGGAG ATCCTCAAGA TCAACTTGCA GTTGCTTATC ACCTTATTAT TGACAATCGG 900

AGAATCATGA ACCAAGCCAG TGAATTCTAC CTCGCTTCCA GCCCTCCTTC TGGCTCTTTT 960

ATGGATGACT CTATGCACAT CCCTCCAGGG GTAAAACCTC ACCCAGAGCG GATGCCTCCA 1020

TTGGTAGCAG ATAGTCCCAA AGCAAAATGT CCCCTCGATG CACTGAATAC CACTAAGCCA 1080

AAACCATTGA CTGTGAAAAA GGCCAAGTGG CATTTAGGGA TACGGAGTCA AAGCAAGCCT 1140

TATGATATCA TGGCTGAAGT CTACCGTGCT ATGAAACAAC TGGAGTTTGA ATGGAAGGTG 1200

GTGAATGCTT ATCATCTTAG AGTTCGTAGA AAAAATCCAG TGACGGGGAA TTTCGTAAAA 1260

ATGAGTTTGC AGCTGTATCA GGTTGACAAT CGTAGCTATC TACTGGACTT TAAAAGTATT 1320

GATGATGATG TCATGGAACA AAGATCAGGC TCTTCCACTC CTCAGCGCTC ATGCTCTGCA 1380

GCTCGACTGC ACAGACCAAG ACTGAGTTTT GATTCTGCCT CTGCTGATTA CCAACCACTT 1440

TCGGGGTCTC TCAGTGGCTC CTTCACAGGT AGCATGCCCT CTGTTACACC TCGCCTTGGC 1500

AGCCATACCA TGGATTTCTT TGAAATGTGT GCTAGTCTCA TCATGGCTCT TGCACGCTGA 1560

Domain Profile

S: 19    khketkekvavKiikkkkl.seeslekikrEieilkklkhpniikllevietkkklylvl  77

         +h++t++kvavKi++++k+ s + + kikrEi+ lk ++hp+iikl++vi+t +++++v+

Q: 3     EHQLTGHKVAVKILNRQKIrSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVM  62

         799***************96667788**********************************

S: 78    eyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgivHrDlKpeNllldkkeni  137

         ey+sggeLfdyi ++gr++e+ear+lf+q++sav+Y+h++ +vHrDlKpeN+lld+++n

Q: 63    EYVSGGELFDYICKHGRVEETEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNA  122

         ************************************************************

S: 138   kiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvDvWslGvvLyalvtgklP  197

         kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+vD+Ws+Gv+Lyal++g+lP

Q: 123   KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLP  182

         ************************************************************

S: 198   fdeenlkellekilkgkleipkklskelesLlrklLvvdpekRatieeilkhewl  252

         fd++++ +l++ki  g + ip++l++++++Ll ++L+vdp kRati+++++hew+

Q: 183   FDDDHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDMREHEWF  237

         ******************************************************7

Domain Sequence
(FASTA)

EHQLTGHKVA VKILNRQKIR SLDVVGKIKR EIQNLKLFRH PHIIKLYQVI STPTDFFMVM 60

EYVSGGELFD YICKHGRVEE TEARRLFQQI LSAVDYCHRH MVVHRDLKPE NVLLDAHMNA 120

KIADFGLSNM MSDGEFLRTS CGSPNYAAPE VISGRLYAGP EVDIWSCGVI LYALLCGTLP 180

FDDDHVPTLF KKIRGGVFYI PEYLNRSVAT LLMHMLQVDP LKRATIKDMR EHEWF 235

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0004679	; F:AMP-activated protein kinase activity
GO:0005524	; F:ATP binding
GO:0003682	; F:chromatin binding
GO:0035174	; F:histone serine kinase activity
GO:0042149	; P:cellular response to glucose starvation
GO:0042593	; P:glucose homeostasis
GO:0008610	; P:lipid biosynthetic process
GO:0043066	; P:negative regulation of apoptotic process
GO:0032007	; P:negative regulation of TOR signaling cascade
GO:0010508	; P:positive regulation of autophagy
GO:0042752	; P:regulation of circadian rhythm

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013