EKS-ANC-00222

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00222

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	427.3	1.9E-128	24	284	261

Status

Unreviewed

Ensembl Protein

ENSACAP00000007073

UniProt Accession

G1KGA4;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPKAPK3

Gene Synonyms/Alias

MAPKAPK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000007166	ENSACAP00000007073	ENSACAT00000007225

Organism

Anolis carolinensis

Functional Description

Protein Length

364

Protein Sequence
(FASTA)

PGLGGAPDRC REIKKHAVTD DYKISKRVLG LGINGRVLEC FHKVTGRKCA LKLLYDSPKA 60

RQEVDHHWRA SGCPHIVHIL DVYENIHHGK RCLLIIMECM EGGELFSRIQ ERGDQAFTEK 120

EASEIMRDIG TAIQYLHGMN IAHRDVKPEN LLYTSKEKDA VLKLTDFGFA KETTIQNALQ 180

TPCYTPYYVA PEVLGPEKYD KSCDMWSLGV IMYILLCGFP PFYSNTGQAI SPGMKRRIRM 240

GQYGFPNPEW SEVSDEAKQL IRQLLKTDPT ERMTISQFMN HPWINQSMVV PPTPLHTARV 300

LQEDKDHWDE VKEEMTSALA TMRVDYDQVK IKDLKTSNNR LLNKRRKKQK QGGSSSASPG 360

CNNQ 364

Nucleotide Sequence
(FASTA)

CCGGGGTTAG GTGGGGCCCC CGATCGATGT CGGGAGATAA AGAAACATGC TGTTACAGAT 60

GACTACAAAA TCTCCAAGCG AGTCCTGGGC CTTGGCATTA ATGGCAGAGT ATTGGAGTGC 120

TTCCACAAAG TAACAGGGAG GAAATGTGCT TTAAAGCTCT TGTATGATAG CCCAAAAGCA 180

CGACAAGAAG TGGATCATCA TTGGCGGGCT TCTGGCTGTC CCCACATCGT CCACATCCTG 240

GATGTTTATG AAAATATACA TCATGGGAAG AGATGCCTCC TAATCATCAT GGAATGCATG 300

GAGGGAGGGG AGCTGTTCAG CAGAATCCAG GAGCGAGGAG ACCAAGCATT TACAGAAAAA 360

GAGGCCTCTG AAATAATGAG GGACATTGGA ACAGCCATCC AGTATTTACA TGGAATGAAT 420

ATAGCCCATA GAGATGTCAA GCCAGAAAAT CTGCTTTATA CATCTAAAGA GAAGGATGCA 480

GTGCTCAAGC TCACAGACTT TGGGTTTGCC AAAGAGACAA CAATACAGAA TGCCCTGCAA 540

ACACCATGTT ACACTCCATA CTATGTAGCC CCAGAAGTCC TTGGTCCAGA GAAGTATGAC 600

AAGTCCTGTG ATATGTGGTC TCTTGGTGTC ATCATGTACA TTCTCTTGTG TGGGTTCCCT 660

CCATTCTACT CCAATACTGG CCAAGCCATT TCTCCAGGAA TGAAGAGGAG AATTCGGATG 720

GGGCAGTATG GATTTCCAAA CCCTGAATGG TCAGAGGTGT CTGATGAAGC TAAGCAGCTA 780

ATTCGCCAGT TGCTGAAGAC GGATCCAACA GAGAGAATGA CAATTTCTCA ATTTATGAAT 840

CACCCTTGGA TTAATCAGTC CATGGTGGTG CCCCCGACCC CTCTTCACAC GGCCCGTGTC 900

CTACAGGAGG ATAAAGATCA CTGGGATGAA GTGAAGGAGG AAATGACAAG TGCCTTGGCA 960

ACCATGAGAG TGGACTACGA CCAAGTAAAA ATTAAGGATT TGAAAACCTC TAACAACCGT 1020

CTCCTCAACA AACGGCGCAA GAAGCAAAAA CAAGGAGGCT CTTCTTCGGC ATCTCCTGGT 1080

TGTAACAACC AA 1092

Domain Profile

S: 2     lteevlGeGisgkvlecvkkktgekyalkilkdrkkvrrevelhvqasghknivelidvf  61

         +++ vlG Gi+g+vlec++k tg+k+alk+l+d++k+r+ev++h++asg+++iv+++dv+

Q: 24    ISKRVLGLGINGRVLECFHKVTGRKCALKLLYDSPKARQEVDHHWRASGCPHIVHILDVY  83

         7899********************************************************

S: 62    ensfedekrlllvlekleGGellsriqer..kaftekeasevvkdiasalkflhskniah  119

         en+++++++ll+++e++eGGel+sriqer  +aftekease+++di++a+++lh +niah

Q: 84    ENIHHGKRCLLIIMECMEGGELFSRIQERgdQAFTEKEASEIMRDIGTAIQYLHGMNIAH  143

         ******************************9*****************************

S: 120   rDlkpenlLyeskeknapvklcDfglaketeeeeelktpcltaeyvaPevleaekeeall  179

         rD+kpenlLy+skek+a++kl+Dfg+aket+ +++l+tpc+t++yvaPevl++ek

Q: 144   RDVKPENLLYTSKEKDAVLKLTDFGFAKETTIQNALQTPCYTPYYVAPEVLGPEK-----  198

         *******************************************************.....

S: 180   ydksCDlWslGvilyillcGypPfyskkgraiskklkeriqegkyefPeeeWsevseeak  239

         ydksCD+WslGvi+yillcG+pPfys++g+ais+++k+ri++g+y fP++eWsevs+eak

Q: 199   YDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRMGQYGFPNPEWSEVSDEAK  258

         ************************************************************

S: 240   dlirklLkrdpkerltieevlnhpwv  265

         +lir+lLk+dp+er+ti++++nhpw+

Q: 259   QLIRQLLKTDPTERMTISQFMNHPWI  284

         *************************8

Domain Sequence
(FASTA)

ISKRVLGLGI NGRVLECFHK VTGRKCALKL LYDSPKARQE VDHHWRASGC PHIVHILDVY 60

ENIHHGKRCL LIIMECMEGG ELFSRIQERG DQAFTEKEAS EIMRDIGTAI QYLHGMNIAH 120

RDVKPENLLY TSKEKDAVLK LTDFGFAKET TIQNALQTPC YTPYYVAPEV LGPEKYDKSC 180

DMWSLGVIMY ILLCGFPPFY SNTGQAISPG MKRRIRMGQY GFPNPEWSEV SDEAKQLIRQ 240

LLKTDPTERM TISQFMNHPW I 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0044351	; P:macropinocytosis
GO:0018105	; P:peptidyl-serine phosphorylation
GO:0006950	; P:response to stress
GO:0002224	; P:toll-like receptor signaling pathway

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013