EPS-ANC-00038

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ANC-00038

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	85.7	3.8E-24	55	333	279

Status

Unreviewed

Ensembl Protein

ENSACAP00000007513

UniProt Accession

G1KGX0;

Protein Name

Protein Synonyms/Alias

Gene Name

TAB1

Gene Synonyms/Alias

TAB1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000007616	ENSACAP00000007513	ENSACAT00000007673

Organism

Anolis carolinensis

Functional Description

Protein Length

501

Protein Sequence
(FASTA)

MAAARRSLLQ SEQLSSWTDD LPLCQLSGVG SAPNRSYAAD GKGTEIHPLE DNWLKFRSEN 60

NCYLYGVFNG YDGNRITNFV GERLSAELLL GQLNADHDDA DVRRILLQAF DVVERSFLES 120

IDDALAEKAS LQSQLPEGVP HHQLPSQYQK ILERLKAVEK EISGGAMAIV AVILNNKLYI 180

ANVGTNRALL CKSTVDGLQV TQLNMDHTTE NEDELFRFSQ LGLDAAKLKQ VGTICGQEST 240

RRIGDYKVKY GYSDIELLSA AKSKPVIAEP EIHRGQPLDG VTGFLVLMSE GLYKALEAAH 300

GPGQANQEIA AMIATEFAKQ TSLDAVAQAV VDRVKRIHCD TYASGGERSK FCSRHEDMTL 360

LVRNFGYPLG EMSQPTLTPT QGGRVYPVSV PYSSAQSTSK TSVTLSLVMP SQGQMVNGAH 420

SSSTLDEATP TLTNQSPTVT LQSTNTHTQS SSSSSDGGLF RSRPSHSLQP DEDGRVEPYV 480

DFAEFYRLWN MDHSEQGALA V 501

Nucleotide Sequence
(FASTA)

ATGGCGGCCG CGAGGAGGAG TCTACTGCAG AGTGAGCAGC TGTCAAGTTG GACAGATGAC 60

TTGCCTCTTT GTCAACTCTC GGGTGTGGGT TCAGCTCCTA ATCGTTCCTA TGCTGCAGAT 120

GGAAAGGGGA CAGAAATCCA CCCCTTAGAG GATAATTGGT TGAAATTCAG AAGCGAAAAC 180

AACTGCTACC TCTATGGAGT CTTCAATGGT TATGATGGCA ACCGGATTAC TAATTTTGTG 240

GGAGAAAGGC TGTCTGCAGA GCTCCTGTTG GGCCAGCTGA ATGCAGATCA TGATGATGCT 300

GACGTGCGTA GAATTCTACT GCAGGCTTTT GACGTGGTGG AACGGAGCTT CTTAGAGTCA 360

ATTGATGATG CTTTGGCAGA GAAGGCCAGC CTGCAATCCC AGTTGCCAGA GGGAGTCCCC 420

CATCATCAGC TTCCCTCTCA GTATCAGAAA ATCTTAGAGC GGTTGAAGGC TGTAGAAAAA 480

GAAATCTCTG GAGGAGCCAT GGCTATTGTG GCAGTCATTT TGAACAACAA ACTCTATATC 540

GCCAATGTAG GAACGAACCG TGCCCTCTTG TGCAAATCTA CCGTAGATGG ACTGCAAGTG 600

ACACAGCTCA ATATGGATCA CACCACAGAG AATGAAGATG AGCTGTTTCG CTTTTCTCAA 660

TTGGGCTTGG ATGCAGCGAA ATTGAAGCAA GTGGGCACCA TATGTGGGCA GGAAAGTACC 720

CGGCGTATCG GGGATTATAA GGTTAAATAT GGCTACAGTG ACATTGAACT TCTAAGTGCT 780

GCAAAATCCA AGCCAGTCAT AGCAGAGCCT GAAATCCACC GAGGCCAACC ACTGGATGGA 840

GTCACAGGCT TTCTTGTTCT GATGTCGGAA GGACTCTACA AAGCACTGGA AGCAGCTCAT 900

GGGCCAGGGC AAGCCAATCA GGAGATTGCG GCCATGATTG CCACAGAATT TGCTAAACAA 960

ACTTCACTGG ATGCTGTGGC TCAAGCAGTT GTGGATCGAG TCAAGCGCAT TCACTGTGAT 1020

ACATATGCCA GTGGTGGTGA ACGGTCCAAG TTCTGTTCTC GGCACGAGGA CATGACTCTG 1080

CTGGTGAGGA ATTTTGGGTA CCCGCTGGGT GAGATGAGCC AGCCCACTCT CACCCCAACG 1140

CAAGGTGGTC GTGTTTATCC TGTATCGGTG CCATACTCCA GTGCCCAAAG TACAAGCAAG 1200

ACCAGCGTAA CACTATCCCT TGTCATGCCT TCCCAAGGTC AAATGGTCAA TGGTGCTCAT 1260

AGCAGCTCCA CGTTGGATGA AGCTACACCC ACCCTCACTA ATCAAAGCCC AACAGTGACC 1320

CTCCAGTCTA CCAATACTCA CACTCAGAGC AGCAGCTCAA GCTCAGATGG GGGCCTCTTC 1380

CGCTCCCGTC CCTCTCATTC TCTCCAGCCA GATGAAGATG GGCGGGTTGA GCCTTATGTG 1440

GACTTTGCAG AATTCTACCG CCTCTGGAAC ATGGACCACA GTGAGCAAGG GGCACTGGCT 1500

GTGTAA 1506

Domain Profile

S: 27    kspekkdrlaffgvyDGhggsevakfcseklheilaeelesseseerkvkkalakaFlst  86

         k +++++  +++gv++G  g+++++f+ e+l+  l     + + ++++v+++l +aF  +

Q: 55    KFRSENN-CYLYGVFNGYDGNRITNFVGERLSAELLLGQLNADHDDADVRRILLQAFDVV  113

         4445555.69*********************9766655555999****************

S: 87    deel...................................kvleeksldidk...sGstav  108

         ++ +                                   + l+++ +   k    G+ a

Q: 114   ERSFlesiddalaekaslqsqlpegvphhqlpsqyqkilERLKAV-E---KeisGGAMAI  169

         ********************************9998444333333.3...235599****

S: 109   valikdsklyvanvGdSravLcrng.k...avelssdHkpsredEleRieeag.gsvilk  163

         va+i ++kly+anvG  ra+Lc++  +   + +l  dH++++edEl R ++ g +   lk

Q: 170   VAVILNNKLYIANVGTNRALLCKSTvDglqVTQLNMDHTTENEDELFRFSQLGlDAAKLK  229

         **********************97634666999999*****************8777777

S: 164   dgaRvlGvLavsRalGdlylk..............pyvtpePevtshr.ltsedefliLa  208

         +   ++G+ + +R +Gd+++k              + v++ePe++  + l+  + fl+L

Q: 230   QVGTICGQ-ESTRRIGDYKVKygysdiellsaaksKPVIAEPEIHRGQpLDGVTGFLVLM  288

         64499995.99***********************999*******99761566666*****

S: 209   sDGlwdvvs........neeavslvrdvlekkeaeqeaakkLvkl  245

         s Gl++ ++        n+e+ +++     k+++++++a+ +v++

Q: 289   SEGLYKALEaahgpgqaNQEIAAMIATEFAKQTSLDAVAQAVVDR  333

         ******986333333335666666655555677777777777766

Domain Sequence
(FASTA)

KFRSENNCYL YGVFNGYDGN RITNFVGERL SAELLLGQLN ADHDDADVRR ILLQAFDVVE 60

RSFLESIDDA LAEKASLQSQ LPEGVPHHQL PSQYQKILER LKAVEKEISG GAMAIVAVIL 120

NNKLYIANVG TNRALLCKST VDGLQVTQLN MDHTTENEDE LFRFSQLGLD AAKLKQVGTI 180

CGQESTRRIG DYKVKYGYSD IELLSAAKSK PVIAEPEIHR GQPLDGVTGF LVLMSEGLYK 240

ALEAAHGPGQ ANQEIAAMIA TEFAKQTSLD AVAQAVVDR 279

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0003824	; F:catalytic activity
GO:0019209	; F:kinase activator activity
GO:0000185	; P:activation of MAPKKK activity
GO:0008152	; P:metabolic process
GO:0007179	; P:transforming growth factor beta receptor signaling pathway

KEGG

InterPros

IPR001932	; PP2C-like.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00332

; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013