EKS-ANC-00477

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00477

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TBCK	387.8	1.6E-116	19	271	253

Status

Unreviewed

Ensembl Protein

ENSACAP00000008246

UniProt Accession

H9GDV1;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100567414

Gene Synonyms/Alias

LOC100567414;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000008343	ENSACAP00000008246	ENSACAT00000008423

Organism

Anolis carolinensis

Functional Description

Protein Length

891

Protein Sequence
(FASTA)

MFPLKDAELG AFTFFASALP NDVCGSNGLP LTPNSIKILG RFQILKTITH PRLCQYVDIS 60

RGKHERLVVV AEHCGRSLED LLRDRKPVSS FKVSCIAFEV LQGLKYMNKH GIVHRALAPR 120

NILLDQEGHI KLAKFGLYHM TAYGADVDFP IGYPSYLAPE VIAQGIIKRS EHTQSEKPSG 180

PKSDVWSLGI ILFELCIGRK LFQSLDVAEK LELILNLGCV DDILTVLAEE HGCLDIIKEV 240

SENVLTLLRK CLTFYPSKRP TPDKLLNDPI FSEISSLYPT FHKPASLFSP TLRCANLTLP 300

EDISQLFEEE NSDYLAERSI EEVYYLWCLA GGDLEKELVN KEIIRSKPPI CTLPIFVLED 360

GESFGQGRDR SFLLDDTTVT LSLCQLRNRL KDVAGEAFYP LLEDDQSNVP HSNSSNELSA 420

AANLPLIIRE RDTEYQLNRI VLFDRLLKAY PYKKNQIWKE ARVDIPPLMR GLTWAALLGV 480

EGDIQAKYDA IDKDTPIPTD RQIEVDIPRC HQYDELLSSP EGHAKFRRVL KAWVVSHPDL 540

VYWQGLDSLC APFLYLNFNN EALAYACMCA FIPKYLYNFF LKDNSHVIQE YLTVFSQMIA 600

FHDPELSNHL NEIGFIPDLY AIPWFLTMFT HVFPLHKIFH LWDTLLLGNS SFPFCIGVAI 660

LQQLRDRLLS NGFNECILLF SDLPEIDIER CVRESINLFC WTPKSATYRQ FAQHPKQTSE 720

ATCTRSLMSC FSSDYQDAPR SDLSRDSIKL NDLKSEVSPR ISAEDLIDLC DLSGPSHFKT 780

PTKKTKSSKP KLLIVDIRNS EDFNRGHISG SINIPFGSAF TAEGELIQCP ATSMLQSFKG 840

RVVVIVGHVA KNAASFAAHL VKIKYPRVCI LDGGINKIKP TGLLTVPSPQ I 891

Nucleotide Sequence
(FASTA)

ATGTTTCCAT TAAAAGATGC AGAACTCGGA GCTTTCACCT TCTTTGCTTC AGCTCTTCCC 60

AATGATGTTT GTGGGAGCAA TGGCCTTCCT TTGACACCAA ACTCCATAAA GATCCTGGGG 120

CGCTTTCAGA TTCTGAAGAC AATTACGCAC CCAAGACTGT GCCAGTATGT GGACATTTCT 180

CGAGGAAAAC ATGAGAGGCT AGTGGTTGTT GCTGAACACT GTGGAAGAAG CCTGGAAGAC 240

TTGCTTCGAG ACAGGAAACC AGTGAGCTCT TTTAAGGTGT CATGTATTGC CTTTGAAGTA 300

TTGCAAGGCT TGAAATATAT GAACAAGCAT GGAATCGTCC ACCGAGCTCT TGCACCTCGA 360

AACATCCTCC TGGATCAAGA GGGACACATT AAATTGGCTA AATTTGGTCT TTATCACATG 420

ACAGCTTATG GTGCTGATGT TGATTTTCCT ATAGGATATC CCTCATATTT GGCACCAGAA 480

GTAATTGCGC AAGGCATTAT CAAACGTAGT GAACATACAC AAAGTGAAAA GCCCTCAGGG 540

CCTAAATCTG ATGTGTGGTC CCTTGGTATT ATATTGTTTG AGCTTTGTAT AGGCAGAAAA 600

CTATTCCAGA GTTTGGATGT AGCTGAAAAG CTCGAACTTA TACTTAACCT TGGTTGTGTG 660

GATGATATTC TAACAGTACT AGCTGAGGAA CATGGATGTT TGGACATTAT TAAGGAGGTT 720

TCTGAAAATG TTTTAACTCT GCTGAGAAAG TGTCTCACAT TCTACCCTTC AAAGAGGCCT 780

ACACCTGACA AACTGCTGAA TGATCCCATT TTCAGTGAAA TATCATCATT ATACCCAACC 840

TTCCACAAAC CTGCCAGCCT TTTCTCACCC ACTCTAAGAT GTGCCAACTT AACTCTTCCT 900

GAGGATATTA GTCAACTGTT TGAAGAGGAA AACTCTGATT ACCTAGCAGA AAGGTCAATT 960

GAAGAAGTTT ATTATCTCTG GTGCTTGGCT GGAGGGGACT TGGAAAAAGA GCTTGTCAAC 1020

AAGGAAATCA TTCGTTCAAA GCCACCCATC TGTACCCTTC CCATTTTTGT GTTGGAGGAT 1080

GGAGAGAGCT TTGGACAGGG GCGAGATAGA AGCTTCCTTT TGGATGACAC AACGGTCACA 1140

CTCTCTCTGT GCCAGCTGAG AAATAGGCTG AAAGATGTTG CTGGGGAAGC CTTTTATCCC 1200

TTGCTTGAAG ATGACCAGTC AAATGTACCC CATTCAAATA GCAGCAATGA ATTATCTGCT 1260

GCTGCTAATC TTCCTCTTAT TATCCGGGAG CGGGACACAG AATATCAGCT AAACAGAATT 1320

GTCCTGTTTG ACAGACTGCT AAAGGCCTAT CCATATAAAA AAAATCAGAT TTGGAAAGAA 1380

GCCAGAGTTG ACATTCCTCC ACTGATGAGG GGTTTAACTT GGGCAGCCTT ACTTGGAGTT 1440

GAGGGTGACA TTCAAGCAAA ATATGATGCC ATTGATAAGG ACACTCCAAT TCCTACAGAC 1500

AGACAAATTG AAGTTGACAT TCCTCGCTGC CATCAGTATG ATGAGTTGCT GTCATCCCCT 1560

GAAGGTCATG CAAAATTTAG ACGGGTGTTG AAAGCATGGG TCGTTTCCCA TCCTGATCTT 1620

GTATATTGGC AAGGTCTTGA CTCTCTTTGT GCACCTTTCT TATATTTAAA TTTCAACAAT 1680

GAAGCTCTGG CCTATGCCTG TATGTGTGCT TTTATTCCTA AATACCTGTA TAATTTCTTT 1740

CTAAAAGACA ATTCACATGT GATTCAAGAA TACCTGACAG TGTTCTCTCA GATGATTGCA 1800

TTCCATGACC CTGAGCTGAG TAACCATCTC AATGAAATTG GCTTCATTCC AGATCTGTAT 1860

GCTATTCCTT GGTTTCTGAC AATGTTTACA CATGTCTTTC CTTTGCACAA AATTTTTCAT 1920

CTGTGGGATA CATTGCTACT TGGGAATTCT TCCTTCCCAT TCTGTATTGG AGTGGCTATT 1980

CTTCAGCAGC TGAGAGACCG ACTTCTCTCT AATGGGTTCA ACGAATGCAT TTTGCTCTTT 2040

TCTGATTTGC CAGAAATTGA CATAGAACGT TGTGTCCGTG AATCAATCAA TCTTTTCTGT 2100

TGGACCCCTA AAAGTGCTAC TTACAGACAG TTTGCACAGC ATCCTAAGCA AACCAGTGAG 2160

GCAACCTGTA CAAGAAGCTT AATGTCCTGT TTCTCATCGG ACTATCAAGA TGCACCAAGA 2220

AGTGACCTGT CTAGGGATTC CATCAAGCTG AATGATCTGA AGTCAGAAGT GTCACCAAGG 2280

ATCTCAGCTG AAGATTTGAT TGACCTATGT GACCTGTCAG GACCCAGCCA CTTCAAGACC 2340

CCAACCAAGA AAACAAAATC CAGCAAGCCA AAGTTGCTTA TTGTTGACAT CCGTAACAGT 2400

GAGGATTTTA ATCGAGGGCA TATATCGGGC AGCATCAATA TCCCATTTGG ATCAGCATTC 2460

ACTGCTGAAG GAGAGCTCAT CCAGTGTCCG GCTACTTCTA TGCTTCAGAG TTTTAAAGGG 2520

AGAGTAGTGG TGATTGTTGG ACACGTAGCA AAGAATGCCG CATCGTTTGC AGCTCATCTA 2580

GTGAAAATCA AATATCCAAG GGTCTGCATT TTGGATGGAG GCATAAACAA AATCAAGCCA 2640

ACTGGTCTGC TGACAGTTCC TTCTCCACAA ATA 2673

Domain Profile

S: 2     laqdkdGsnGlplasnakkilGrfqiLkelqhdrLcqYldisrgkhervivvaehlelsL  61

         l++d++GsnGlpl++n++kilGrfqiLk+++h+rLcqY+disrgkher++vvaeh+++sL

Q: 19    LPNDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCGRSL  78

         799*********************************************************

S: 62    eDllkerkpvseslvlriayevlsgldylnkhnivhralepksilldrkgqkvkLakyGL  121

         eDll++rkpvs  +v +ia+evl+gl+y+nkh+ivhral p++illd++g+ +kLak+GL

Q: 79    EDLLRDRKPVSSFKVSCIAFEVLQGLKYMNKHGIVHRALAPRNILLDQEGH-IKLAKFGL  137

         ***************************************************.********

S: 122   yhltayGkdvdfpigygsylaPerilqd.......edkllaatvksDvWsLglillelil  174

         yh+tayG+dvdfpigy+sylaPe+i+q+        ++  ++++ksDvWsLg+il+el++

Q: 138   YHMTAYGADVDFPIGYPSYLAPEVIAQGiikrsehTQSEKPSGPKSDVWSLGIILFELCI  197

         ********************************999788889*******************

S: 175   gikLfaeldlserlkillklstvdetliklaeekkcldiikklderleallkkCLtllps  234

         g+kLf++ld++e+l+++l+l++vd+ l +laee++cldiik++ e++  ll+kCLt++ps

Q: 198   GRKLFQSLDVAEKLELILNLGCVDDILTVLAEEHGCLDIIKEVSENVLTLLRKCLTFYPS  257

         ************************************************************

S: 235   kRpspdellkekvf  248

         kRp+pd+ll++++f

Q: 258   KRPTPDKLLNDPIF  271

         ***********997

Domain Sequence
(FASTA)

LPNDVCGSNG LPLTPNSIKI LGRFQILKTI THPRLCQYVD ISRGKHERLV VVAEHCGRSL 60

EDLLRDRKPV SSFKVSCIAF EVLQGLKYMN KHGIVHRALA PRNILLDQEG HIKLAKFGLY 120

HMTAYGADVD FPIGYPSYLA PEVIAQGIIK RSEHTQSEKP SGPKSDVWSL GIILFELCIG 180

RKLFQSLDVA EKLELILNLG CVDDILTVLA EEHGCLDIIK EVSENVLTLL RKCLTFYPSK 240

RPTPDKLLND PIF 253

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0005097	; F:Rab GTPase activator activity
GO:0032851	; P:positive regulation of Rab GTPase activity

KEGG

acs:100567414

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR000195	; Rab-GTPase-TBC_dom.
IPR001763	; Rhodanese-like_dom.

Pfam

PF00069	; Pkinase; 1.
PF00566	; RabGAP-TBC; 1.
PF00581	; Rhodanese; 1.

SMARTs

SM00450	; RHOD; 1.
SM00164	; TBC; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS50206	; RHODANESE_3; 1.
PS50086	; TBC_RABGAP; 1.

Prints

Created Date

20-Feb-2013