EPS-ANC-00020

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ANC-00020

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	93.3	1.1E-26	44	135	92

Status

Unreviewed

Ensembl Protein

ENSACAP00000008203

UniProt Accession

H9GDT8;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP12

Gene Synonyms/Alias

DUSP12;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000008356	ENSACAP00000008203	ENSACAT00000008379

Organism

Anolis carolinensis

Functional Description

Protein Length

308

Protein Sequence
(FASTA)

VEVLPGLYLG PAGRGKAAER PPGITALLSV DSEPPGEVGL EDVLHLEALD QPGCDLLSRL 60

DQAAAFIDRI RAKEGAILVQ CHAGVSRSVA VVTAYLMKAN NLPFEEAYTF IRAIKPDAKM 120

NEGFEWQLKL YEKMGCEVDV TSAVYKQYNL QSLTERYSES QDLPKEIFAI DPNNIEQATN 180

CELTYKCRKC RRLLFQSSNI LPHDEGTGLA AFAHKRFSEP APFHCNSRPG CTSYFIEPLQ 240

WMEPMLLGVI EGQLLCPKCT SKLGSFHWHG EQCSCGRWVT PAFQIHKSRV DEAKGLPAGA 300

LLSARKQS 308

Nucleotide Sequence
(FASTA)

GTGGAGGTCC TTCCAGGGCT GTACCTGGGC CCTGCGGGGC GTGGGAAGGC GGCGGAGAGG 60

CCTCCGGGGA TCACGGCCCT CTTGTCTGTG GACTCGGAGC CCCCCGGGGA AGTGGGGCTG 120

GAGGACGTGC TGCATTTGGA GGCCCTCGAC CAGCCCGGCT GCGACCTGCT GAGCCGCTTG 180

GACCAGGCCG CCGCCTTCAT CGACAGAATC CGCGCGAAGG AGGGCGCCAT TCTGGTCCAA 240

TGTCATGCTG GAGTCAGTCG AAGTGTGGCT GTTGTGACTG CCTATTTAAT GAAGGCCAAT 300

AATCTCCCCT TTGAAGAAGC CTACACCTTT ATTAGGGCCA TCAAACCTGA TGCAAAAATG 360

AATGAAGGCT TTGAGTGGCA ACTGAAACTC TATGAAAAAA TGGGGTGTGA GGTTGATGTA 420

ACCAGTGCTG TTTACAAACA GTATAATTTG CAGAGCCTTA CGGAAAGATA CTCTGAATCA 480

CAGGACCTTC CAAAAGAAAT TTTTGCAATT GATCCAAACA ACATTGAGCA GGCGACAAAT 540

TGTGAACTTA CTTACAAATG TCGGAAGTGC CGGCGTCTCC TCTTTCAAAG CTCAAACATC 600

CTACCTCATG ATGAAGGCAC AGGACTGGCA GCTTTTGCTC ACAAAAGGTT TTCAGAGCCT 660

GCCCCTTTTC ACTGTAACAG CAGACCCGGT TGTACTTCTT ACTTCATTGA ACCTCTACAA 720

TGGATGGAGC CAATGCTTTT AGGAGTGATT GAAGGACAGC TTCTGTGCCC AAAGTGTACA 780

TCCAAGTTAG GGTCCTTTCA CTGGCACGGT GAGCAGTGTT CATGTGGCCG TTGGGTGACC 840

CCTGCCTTCC AGATTCACAA GAGCCGTGTC GATGAAGCAA AAGGACTTCC AGCTGGTGCT 900

CTGCTCAGTG CGAGAAAGCA AAGTTAG 927

Domain Profile

S: 56    knipvdDsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkvegls  115

         +++++ D++  dll+ +d+aa+fid+++ k+g++lv C+aGvsRS+++v+aYLmk ++l

Q: 44    LHLEALDQPGCDLLSRLDQAAAFIDRIRAKEGAILVQCHAGVSRSVAVVTAYLMKANNLP  103

         567899******************************************************

S: 116   lsdAieavkrkrpsiepnegfleQLlelekkl  147

         +++A++ +++ +p +++negf +QL ++ek++

Q: 104   FEEAYTFIRAIKPDAKMNEGFEWQLKLYEKMG  135

         ******************************97

Domain Sequence
(FASTA)

LHLEALDQPG CDLLSRLDQA AAFIDRIRAK EGAILVQCHA GVSRSVAVVT AYLMKANNLP 60

FEEAYTFIRA IKPDAKMNEG FEWQLKLYEK MG 92

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR016278	; DUSP12.
IPR000387	; Tyr/Dual-specificity_Pase.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

Created Date

20-Feb-2013