EKS-ANC-00201

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00201

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	496.1	2.1E-149	4	287	284

Status

Unreviewed

Ensembl Protein

ENSACAP00000008492

UniProt Accession

G1KI16;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL2

Gene Synonyms/Alias

CDKL2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000008598	ENSACAP00000008492	ENSACAT00000008674

Organism

Anolis carolinensis

Functional Description

Protein Length

566

Protein Sequence
(FASTA)

MEKYEILGLV GEGSYGMVMK CRNKENGRVV AIKKFLESED DKMVKKIAMR EIKLLKQLRH 60

ENLVNLLEVC KKKKRWYLVF EFVDHTVLDD LEMFPNGLDY NRVRKYLFQI IKGIGFCHSH 120

NIIHRDIKPE NILVSYSGII KLCDFGFART LAAPGEAYTD YVATRWYRAP ELLVGDIKYG 180

KAVDVWAIGC LVTEMLTGEP LFPGDSDIDQ LYHIMKSMGN LIPRHQELFY KNPLFAGVRL 240

LDVKDLEPLE KRYSKLSVAV IEFTKRCLQP DPDKRPSCAE LLQCDLFNKD GFAERCGGKR 300

FAQELKGKIQ KERDHPLPKK SKIIRKDKDD SIEERKMLVI QDLSVDSKIK DSKLFRKKLS 360

KADIEKSGRS SNTSFLYENG AGQVKAIPPV TLKDSCSSLD YTKNPSMVIP PITQNCSTMP 420

SSISGTGTKL GTHNYRTDEK TKIYFNPFIK QGKKSPQGHY SMNLTALISN ENSVLQTNKK 480

RWEFPRTNVR LPELNHSHLP ELKCVDDIAR NSRFLKKENK VVSESRMPSL ATIDLQNSSL 540

ALHQISGISL QDATEATFPR VEHYKH 566

Nucleotide Sequence
(FASTA)

ATGGAAAAGT ATGAGATCCT TGGTCTTGTG GGAGAAGGAA GCTACGGAAT GGTGATGAAA 60

TGTAGGAACA AGGAGAATGG CAGAGTGGTT GCCATCAAGA AATTTTTGGA AAGTGAGGAT 120

GATAAGATGG TTAAAAAAAT TGCCATGAGG GAAATTAAGC TTCTCAAGCA ATTAAGGCAT 180

GAAAACCTGG TGAACCTGCT GGAAGTTTGT AAGAAGAAAA AAAGATGGTA CCTAGTGTTT 240

GAATTTGTGG ACCACACAGT CCTTGATGAT CTTGAGATGT TTCCAAATGG CCTGGATTAT 300

AATAGAGTTC GAAAATACTT ATTTCAAATT ATCAAGGGGA TAGGATTTTG TCATAGTCAT 360

AATATCATAC ACAGAGATAT TAAGCCTGAG AATATATTGG TGTCCTATTC AGGAATCATC 420

AAGCTCTGTG ACTTTGGTTT TGCACGAACA CTAGCAGCCC CAGGTGAAGC ATACACAGAT 480

TATGTAGCAA CACGGTGGTA TCGAGCTCCC GAGCTGCTGG TTGGAGATAT CAAATATGGC 540

AAGGCTGTAG ATGTGTGGGC TATTGGCTGC CTGGTGACAG AAATGCTTAC AGGAGAACCC 600

CTTTTCCCTG GTGACTCTGA TATTGACCAA TTGTACCATA TTATGAAAAG TATGGGTAAC 660

TTAATACCAA GGCATCAAGA ATTGTTCTAT AAAAATCCTC TCTTTGCTGG GGTGAGATTG 720

CTTGACGTTA AGGATCTTGA ACCTCTTGAA AAACGGTATT CCAAGCTTTC TGTTGCAGTC 780

ATAGAATTTA CTAAGCGGTG TCTGCAGCCT GATCCAGACA AAAGGCCATC TTGTGCTGAA 840

CTCTTGCAAT GTGATCTGTT TAACAAAGAC GGTTTTGCTG AAAGATGTGG GGGGAAAAGA 900

TTTGCTCAAG AACTTAAAGG CAAGATTCAG AAAGAAAGAG ACCACCCTTT GCCTAAGAAG 960

TCAAAAATTA TTAGGAAAGA TAAAGATGAT TCAATTGAAG AAAGAAAAAT GCTTGTAATC 1020

CAGGACCTGA GTGTTGATTC AAAGATCAAA GACTCGAAGC TGTTTCGAAA GAAATTGTCC 1080

AAGGCTGATA TAGAGAAATC TGGCAGATCT TCAAATACAA GTTTCCTGTA TGAGAACGGA 1140

GCTGGACAAG TCAAAGCCAT TCCTCCAGTA ACATTGAAAG ATTCATGCAG CAGTCTGGAT 1200

TATACAAAGA ACCCCAGCAT GGTGATTCCT CCCATTACAC AGAACTGTTC TACCATGCCA 1260

TCCAGTATCA GTGGCACTGG GACAAAATTG GGAACGCATA ACTACAGGAC TGATGAGAAG 1320

ACCAAAATAT ATTTCAATCC ATTCATAAAG CAAGGCAAAA AATCACCACA AGGACATTAT 1380

AGTATGAACC TGACAGCATT GATCTCAAAT GAAAACAGTG TCCTTCAAAC AAACAAGAAA 1440

CGTTGGGAGT TTCCCAGAAC AAACGTGCGT TTGCCAGAAC TGAACCACAG CCATCTCCCT 1500

GAACTCAAGT GTGTAGATGA TATAGCTCGG AATTCCAGAT TTCTGAAGAA AGAAAATAAA 1560

GTTGTTTCGG AATCTCGCAT GCCATCTCTT GCCACAATAG ATCTTCAAAA CTCAAGCTTG 1620

GCCCTGCACC AGATATCTGG AATCTCCTTG CAAGATGCTA CAGAAGCCAC TTTCCCCAGA 1680

GTAGAACACT ACAAACAT 1698

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye lg vGeGsyG+v+kcrnk+ g++vaikkfleseddk+vkkia+reikllkql+henl

Q: 4     YEILGLVGEGSYGMVMKCRNKENGRVVAIKKFLESEDDKMVKKIAMREIKLLKQLRHENL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllev+++kk++ylvfe+vd+tvld+le +pnG+++++v+k+l+qi+k+i fch++nii

Q: 64    VNLLEVCKKKKRWYLVFEFVDHTVLDDLEMFPNGLDYNRVRKYLFQIIKGIGFCHSHNII  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s sg++klcdfGfar+laapg++ytdyvatrwyrapellvgd+kyGk+v

Q: 124   HRDIKPENILVSYSGIIKLCDFGFARTLAAPGEAYTDYVATRWYRAPELLVGDIKYGKAV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGcl++e+ltGeplfpg+sd+dqly+i+k +G+liprhq++f+kn++faGv+l +v

Q: 184   DVWAIGCLVTEMLTGEPLFPGDSDIDQLYHIMKSMGNLIPRHQELFYKNPLFAGVRLLDV  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +dle+lek+y+kl+ +++++ k+cl+ dp++r sc+ell+ ++f

Q: 244   KDLEPLEKRYSKLSVAVIEFTKRCLQPDPDKRPSCAELLQCDLF  287

         ***************************************99987

Domain Sequence
(FASTA)

YEILGLVGEG SYGMVMKCRN KENGRVVAIK KFLESEDDKM VKKIAMREIK LLKQLRHENL 60

VNLLEVCKKK KRWYLVFEFV DHTVLDDLEM FPNGLDYNRV RKYLFQIIKG IGFCHSHNII 120

HRDIKPENIL VSYSGIIKLC DFGFARTLAA PGEAYTDYVA TRWYRAPELL VGDIKYGKAV 180

DVWAIGCLVT EMLTGEPLFP GDSDIDQLYH IMKSMGNLIP RHQELFYKNP LFAGVRLLDV 240

KDLEPLEKRY SKLSVAVIEF TKRCLQPDPD KRPSCAELLQ CDLF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005813	; C:centrosome
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013