EKS-ANC-00198

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00198

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	509.9	1.6E-153	4	284	281

Status

Unreviewed

Ensembl Protein

ENSACAP00000008534

UniProt Accession

H9GE88;

Protein Name

Protein Synonyms/Alias

Gene Name

MAK

Gene Synonyms/Alias

MAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000008708	ENSACAP00000008534	ENSACAT00000008717

Organism

Anolis carolinensis

Functional Description

Protein Length

620

Protein Sequence
(FASTA)

MNRYTTMKQL GDGTYGSVLM GKSNESGELV AIKKMKRKFY SWDECMNLRE VKSLKKLNHA 60

NVIKLKEVIR ENDHLYFVFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG 120

FFHRDMKPEN LLCMGPELVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSVYSSP 180

IDIWAVGSIM AELYTLRPLF PGTSEVDEIF KICQVLGTPK KSDWPEGYQL AAAMNFRFPQ 240

CVPLNLKTLI PNASNEAIQF MSDMLNWDPK KRPTASQALK YPYFQVGQVL GPPPQYLDQK 300

PSHPKSSQPA ELKPCLPKID TVAKLEPVSK PESQPSSENS QHPLQAIQLP QNANNQQPPK 360

QPQPQSFLPA INKNSTSKPV VTGPSNGGVG LKSCRRRWGQ TMLKTMDSWD DFDDSEFGIS 420

YSKKPSIALL HEKKTKESLF SVSESRSPSS GHSGGENRVL KRNDSGISTT SAKQYYLKQS 480

RYLPGVNPKN VSSGAANKEG SHGSWNNPLL SKPIGGLSFS RINAGNPGFA GAAYNGPMGY 540

IPSFHKKEVG SAGQRIQLAP LGPSATEYAE YAWKTKAVRA QLPGLAYNPA TKGMNILTRP 600

QPVQPVHGRT DWVAKYGGHR 620

Nucleotide Sequence
(FASTA)

ATGAATCGCT ACACAACAAT GAAGCAACTT GGGGATGGAA CTTATGGCAG TGTGCTAATG 60

GGGAAGAGCA ATGAATCCGG GGAGCTTGTG GCCATCAAAA AAATGAAAAG AAAGTTCTAC 120

TCTTGGGATG AATGTATGAA TTTGAGGGAA GTCAAGTCTC TGAAAAAACT TAATCATGCT 180

AATGTGATAA AGCTGAAAGA AGTTATTCGA GAAAATGACC ACCTTTATTT TGTCTTCGAA 240

TATATGAAGG AAAATCTCTA TCAGCTAATG AAAGATAGAA ATAAATTGTT CCCGGAGTCT 300

GTCATCAGGA ACATTATGTA TCAGATATTA CAAGGCTTAG CTTTTATACA CAAACATGGA 360

TTTTTCCACC GAGATATGAA ACCTGAAAAC CTTCTCTGCA TGGGCCCAGA ACTTGTTAAA 420

ATAGCTGATT TTGGACTAGC TAGAGAACTG AGATCTCAAC CTCCATACAC TGATTATGTT 480

TCTACTAGAT GGTATCGTGC ACCTGAGGTT TTGTTGAGAT CTTCCGTTTA TAGTTCTCCT 540

ATTGACATAT GGGCTGTCGG CAGCATCATG GCTGAACTGT ACACACTAAG GCCACTTTTT 600

CCGGGAACAA GTGAAGTTGA TGAAATCTTC AAGATTTGTC AAGTGTTAGG AACACCGAAG 660

AAGAGTGATT GGCCAGAAGG ATACCAACTT GCTGCGGCAA TGAATTTCCG TTTCCCTCAG 720

TGTGTTCCCC TGAACCTAAA AACTCTCATT CCAAATGCTA GCAATGAAGC AATACAATTT 780

ATGAGTGATA TGCTGAACTG GGATCCAAAG AAACGACCTA CTGCAAGTCA GGCACTGAAG 840

TATCCTTACT TCCAAGTGGG ACAGGTTTTA GGACCACCTC CACAATATCT GGATCAGAAG 900

CCCTCTCATC CCAAGTCATC TCAACCTGCA GAGCTAAAGC CATGTCTACC CAAGATAGAC 960

ACTGTAGCAA AACTAGAACC TGTATCGAAA CCAGAATCCC AACCTTCATC AGAGAATAGC 1020

CAACATCCCC TCCAGGCAAT TCAGCTGCCA CAGAATGCAA ACAATCAGCA ACCACCAAAA 1080

CAGCCACAGC CACAGTCATT CCTTCCTGCC ATCAATAAAA ACTCAACATC AAAGCCAGTG 1140

GTCACAGGAC CCTCAAATGG TGGAGTGGGC TTGAAAAGCT GTCGGCGTCG ATGGGGTCAG 1200

ACTATGTTAA AGACCATGGA TAGTTGGGAT GATTTTGATG ATTCAGAATT TGGAATTTCA 1260

TATTCTAAGA AGCCCAGCAT TGCTTTATTA CATGAAAAGA AAACAAAAGA ATCTCTTTTT 1320

AGTGTTTCTG AGTCCAGGTC CCCCAGCTCT GGCCACTCAG GAGGAGAAAA CAGGGTTCTG 1380

AAGAGAAATG ATTCTGGAAT ATCAACAACA TCAGCAAAAC AGTACTACTT AAAACAGTCA 1440

AGATACCTAC CTGGTGTAAA CCCCAAGAAT GTTTCCTCAG GAGCAGCTAA TAAAGAAGGT 1500

TCCCATGGTA GCTGGAACAA CCCCTTGCTT TCAAAACCAA TAGGAGGTCT GTCTTTTAGT 1560

CGAATCAATG CAGGAAATCC TGGCTTTGCA GGTGCTGCTT ACAATGGCCC TATGGGATAC 1620

ATTCCTTCTT TCCATAAAAA AGAGGTTGGT TCAGCTGGTC AAAGGATACA ACTAGCACCT 1680

CTTGGTCCGT CAGCCACAGA ATATGCAGAA TACGCTTGGA AAACTAAAGC CGTTCGAGCA 1740

CAGTTACCCG GGCTTGCATA TAACCCGGCC ACAAAAGGCA TGAACATTTT AACTCGCCCA 1800

CAGCCAGTAC AACCAGTGCA TGGAAGAACG GACTGGGTGG CCAAGTATGG AGGGCATCGA 1860

TAG 1863

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++k+lGdGt+g+vl++ks+++gelvaikkmkrkf+s++e++nlrevkslkkln h+n+

Q: 4     YTTMKQLGDGTYGSVLMGKSNESGELVAIKKMKRKFYSWDECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         iklkevi  rend+ly+v+e+m+enlyql+kdr+kl++es++++i+yqil+glafihkhg

Q: 63    IKLKEVI--RENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrd+kPen+l++g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs+vyssp

Q: 121   FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavG+++ae+++lrplfPG+se+d+ifki++vlGtPkk++w+e+y+la a+n++fpq

Q: 181   IDIWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLAAAMNFRFPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++ +lktl++nas+ea++ ++d+l++dP++r+ta+qalkypyf

Q: 241   CVPLNLKTLIPNASNEAIQFMSDMLNWDPKKRPTASQALKYPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTMKQLGDG TYGSVLMGKS NESGELVAIK KMKRKFYSWD ECMNLREVKS LKKLNHANVI 60

KLKEVIREND HLYFVFEYMK ENLYQLMKDR NKLFPESVIR NIMYQILQGL AFIHKHGFFH 120

RDMKPENLLC MGPELVKIAD FGLARELRSQ PPYTDYVSTR WYRAPEVLLR SSVYSSPIDI 180

WAVGSIMAEL YTLRPLFPGT SEVDEIFKIC QVLGTPKKSD WPEGYQLAAA MNFRFPQCVP 240

LNLKTLIPNA SNEAIQFMSD MLNWDPKKRP TASQALKYPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013