EKS-ANC-00393

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00393

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/PDGFR	189.5	9.8E-56	566	683	118

Status

Unreviewed

Ensembl Protein

ENSACAP00000009065

UniProt Accession

G1KIN7;

Protein Name

Protein Synonyms/Alias

Gene Name

FLT3

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000009188	ENSACAP00000009065	ENSACAT00000009258

Organism

Anolis carolinensis

Functional Description

Protein Length

688

Protein Sequence
(FASTA)

CSLNSQGIGN VYKAAESVEV DVLESVEIKA EMNITGSITC LWIFREIQNG CNMSLNSDNR 60

HVLSIVFPKI RETEAGNHSL SIQTEMNNYT VIFTFLVRHN FQLSSTPRKP YFIKNERTDT 120

VSCISEGYPK PVIKWFFCNG PDESCGTYIF SPNEDLHGIK KEQVNLKQDS LAYYAHVWCC 180

AANELGRKCT KLYTIDRNVS SRNTVQELFL KVGDPLLLRC RAKYSNFDFE NKWYFENKKL 240

MKVIWFSLNK LNNGSYWIKN QYAFALSVEH SNGGRYTCYS EKLAMNQSIL VTVLDKGFIN 300

ITDFTEELEV GIEETTCLEV KLKAYPPITC IWIFSQMSFP CKQNYTDDYS IGIFCDHKYQ 360

AGEYEFYAEN SDSFVKRKLK LYVKRKPEVN MISTPNAQDT ISCISESNPA SSWVWRECPR 420

KDINCTEITT GITNDIRKGK TFGSWSTTST LRTSEVEDGF WLECCANNSF GQSCQTHTVD 480

LKGTIPPLLS IFAPPDNMAL YGVIGFCVPL IMALCLLICQ KYRKQVRYES QLQMIQMVGP 540

SDNEYIYVDF NEVEYDLKWE FPRENLEFGQ VLGSGAFGKV VNAVAYGISE TGVSVQVAVK 600

MLKEKYGSSE KDALMSELKM MIHIGKHENI VNLLGACTMS GPIYLIFEYC CYGDLLNYLR 660

SKRDMFHKTW TDIFREPNFS FYQSFPGH 688

Nucleotide Sequence
(FASTA)

TGTTCCCTGA ATTCTCAAGG CATTGGGAAT GTCTATAAAG CAGCAGAAAG TGTGGAAGTT 60

GATGTGCTTG AAAGTGTTGA AATAAAAGCA GAAATGAATA TCACGGGCAG CATCACCTGT 120

CTTTGGATTT TCAGAGAAAT CCAGAATGGC TGTAACATGT CTCTGAATTC AGACAATCGG 180

CATGTTCTTT CTATTGTGTT TCCAAAGATC AGAGAGACAG AAGCTGGAAA TCATTCACTG 240

TCAATACAAA CTGAAATGAA TAACTACACA GTCATATTTA CATTTCTTGT GAGACATAAT 300

TTTCAGTTAT CAAGCACCCC AAGGAAACCA TATTTCATCA AAAATGAACG TACCGACACT 360

GTCAGTTGCA TATCAGAAGG ATACCCCAAA CCAGTTATAA AATGGTTTTT TTGTAATGGC 420

CCTGATGAAA GCTGTGGAAC ATACATTTTC TCCCCAAATG AAGATCTGCA TGGAATAAAG 480

AAGGAACAAG TTAATCTAAA ACAAGACAGC CTGGCATATT ATGCACATGT GTGGTGCTGT 540

GCAGCTAATG AGCTTGGTCG GAAATGCACT AAACTCTACA CAATAGATCG AAATGTATCA 600

TCAAGAAACA CTGTACAAGA ATTATTTCTT AAAGTTGGAG ATCCACTACT CTTACGCTGT 660

CGAGCCAAGT ATTCCAATTT TGACTTTGAA AATAAGTGGT ATTTTGAAAA CAAGAAATTA 720

ATGAAGGTAA TATGGTTTTC TTTGAATAAA CTGAATAATG GCTCATATTG GATTAAGAAT 780

CAATATGCAT TTGCTTTGTC GGTGGAACAT TCTAATGGGG GACGGTATAC CTGTTATTCT 840

GAAAAACTTG CTATGAATCA AAGCATTTTG GTTACAGTTT TAGATAAAGG ATTTATCAAT 900

ATCACTGACT TCACAGAAGA GTTGGAGGTT GGCATAGAGG AAACAACTTG CCTTGAAGTT 960

AAATTGAAAG CATACCCACC AATCACATGT ATTTGGATAT TTTCCCAAAT GTCATTTCCT 1020

TGTAAGCAAA ATTACACCGA TGATTACAGT ATAGGAATAT TCTGTGACCA TAAATACCAA 1080

GCAGGTGAAT ATGAGTTCTA TGCAGAAAAT AGTGATTCGT TTGTGAAGAG AAAATTAAAA 1140

CTCTATGTTA AAAGAAAACC AGAAGTAAAT ATGATTTCAA CACCAAATGC ACAAGACACA 1200

ATTTCTTGCA TCTCTGAGAG CAATCCTGCA TCATCCTGGG TCTGGAGGGA GTGTCCTAGA 1260

AAGGATATAA ATTGTACAGA AATCACGACT GGAATTACAA ATGACATCCG TAAAGGAAAG 1320

ACCTTTGGTT CCTGGAGCAC AACAAGCACT TTACGCACAA GTGAAGTAGA AGATGGCTTT 1380

TGGCTTGAGT GTTGTGCAAA CAATTCATTT GGTCAATCCT GTCAAACACA CACCGTTGAC 1440

CTTAAAGGTA CTATACCACC ACTCCTATCA ATATTTGCTC CACCTGATAA TATGGCATTA 1500

TATGGAGTTA TTGGATTCTG CGTACCACTC ATCATGGCAC TGTGCTTATT AATTTGCCAG 1560

AAATACAGAA AGCAAGTTAG GTACGAGAGC CAGCTACAAA TGATTCAGAT GGTTGGCCCT 1620

TCTGACAATG AATATATCTA TGTTGATTTC AATGAGGTTG AATATGATCT GAAGTGGGAG 1680

TTCCCCAGAG AGAACCTGGA ATTTGGGCAA GTACTTGGAT CTGGTGCCTT TGGGAAAGTG 1740

GTGAATGCTG TTGCATATGG GATCAGTGAA ACAGGAGTGT CAGTCCAGGT TGCTGTCAAA 1800

ATGCTCAAAG AAAAATATGG TTCCTCTGAG AAAGATGCTC TCATGTCCGA ACTCAAAATG 1860

ATGATCCATA TTGGGAAACA TGAAAACATT GTGAATCTCT TAGGAGCTTG CACCATGTCA 1920

GGGCCAATTT ATCTGATTTT TGAATACTGT TGCTATGGAG ATCTTTTGAA CTACTTACGA 1980

AGCAAAAGGG ATATGTTTCA CAAGACGTGG ACTGATATCT TCAGAGAACC TAACTTCAGT 2040

TTTTACCAGA GTTTTCCAGG TCAT 2064

Domain Profile

S: 1     lelGkvlGsGafGkvveatayGlsksdavlkvavkmlkstarssekealmselkilshlG  60

         le+G+vlGsGafGkvv+a ayG+s+++++++vavkmlk++  ssek+almselk++ h+G

Q: 566   LEFGQVLGSGAFGKVVNAVAYGISETGVSVQVAVKMLKEKYGSSEKDALMSELKMMIHIG  625

         79**********************************************************

S: 61    ehenivnllGactkgGpiyviteyccyGdllnylrrkresflkkslekkkekeeelds  118

         +henivnllGact++Gpiy+i+eyccyGdllnylr+kr+ f+k+++++++e+++++++

Q: 626   KHENIVNLLGACTMSGPIYLIFEYCCYGDLLNYLRSKRDMFHKTWTDIFREPNFSFYQ  683

         *****************************************************99875

Domain Sequence
(FASTA)

LEFGQVLGSG AFGKVVNAVA YGISETGVSV QVAVKMLKEK YGSSEKDALM SELKMMIHIG 60

KHENIVNLLG ACTMSGPIYL IFEYCCYGDL LNYLRSKRDM FHKTWTDIFR EPNFSFYQ 118

Keyword

Complete proteome; Phosphoprotein; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0004714	; F:transmembrane receptor protein tyrosine kinase activity
GO:0007169	; P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

InterPros

IPR007110	; Ig-like.
IPR013783	; Ig-like_fold.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR001824	; Tyr_kinase_rcpt_3_CS.

Pfam

PF07714

; Pkinase_Tyr; 1.

SMARTs

Prosites

PS50835	; IG_LIKE; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00240	; RECEPTOR_TYR_KIN_III; 1.

Prints

Created Date

20-Feb-2013