EKS-ANC-00181

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00181

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Ryk	482.7	2.4E-145	259	525	267

Status

Unreviewed

Ensembl Protein

ENSACAP00000009531

UniProt Accession

G1KJ97;

Protein Name

Protein Synonyms/Alias

Gene Name

RYK

Gene Synonyms/Alias

RYK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000009662	ENSACAP00000009531	ENSACAT00000009728

Organism

Anolis carolinensis

Functional Description

Protein Length

536

Protein Sequence
(FASTA)

ILGIDAELYY VRNDLINHYA LSFNLLVPVE TNNLHFSWHA KAKIEYKLGF QVDNLLAMDM 60

PQANISDQGE VPRTLSVFRV ELSCTGRLDT EVTVLMQLNM TVNASKNITV LNFKRRKMCY 120

KKLEQEVKTP VLEKNSSKAI FDPVNAAPTT STRVFYISVG VCCAVIFLIA IILAVLHLQS 180

MKRIELEDSI SDNSSSQGLS QPSTQTTQYL RADTPNNATP ITSSSGYPTL RIEKNDLKSV 240

TLMEAKAKVK DIAISRERIT LKDVLQEGTF GQIFHGTLIE EKDPSKEKQM FVKTVKDQAS 300

EVQVTMMLTE SCKLRGLHHR NLLPITHVCI EEGEKPMVLL PYMNWGNLKL FLRQCKLVEA 360

NNPQAISQQD LVHMAIQIAC GMSYLARREV IHKDLAARNC VIDDALQVKI TDNALSRDLF 420

PMDYHCLGDN ENRPVRWMAL ESLVNNEFSG ASDVWSFGVT LWELMTLGQT PYVDIDPFEM 480

AAYLKDGYRI AQPINCPDEL FAVMACCWAL DPEERPKFQQ LVQCLTEFHA ALGAYV 536

Nucleotide Sequence
(FASTA)

ATTTTAGGTA TTGATGCAGA ACTTTATTAT GTGAGGAATG ATCTTATCAA TCACTACGCT 60

TTGTCCTTTA ATCTACTAGT ACCTGTAGAA ACAAACAATC TCCATTTCAG TTGGCATGCT 120

AAGGCAAAGA TTGAATATAA GTTGGGATTT CAGGTTGATA ATCTTTTGGC TATGGATATG 180

CCACAGGCCA ATATTTCTGA CCAAGGAGAA GTCCCTCGCA CATTATCTGT GTTTCGAGTG 240

GAACTTTCTT GCACTGGCCG ACTAGACACT GAGGTTACAG TCCTAATGCA ACTCAACATG 300

ACAGTAAATG CTTCCAAAAA TATCACAGTC TTAAATTTCA AACGAAGGAA AATGTGCTAT 360

AAAAAACTTG AACAAGAAGT AAAAACTCCA GTACTGGAGA AAAATAGCAG CAAGGCTATT 420

TTTGATCCTG TAAATGCAGC TCCCACTACA TCTACACGTG TGTTTTATAT CAGTGTTGGT 480

GTTTGCTGTG CAGTCATTTT CCTGATAGCA ATAATACTAG CAGTCTTGCA TCTTCAAAGT 540

ATGAAAAGAA TAGAATTGGA AGACAGCATT AGTGACAACA GTAGCTCACA AGGCTTATCC 600

CAACCTTCAA CTCAAACAAC TCAGTACTTG AGGGCTGATA CACCTAACAA CGCAACACCC 660

ATTACCAGCT CCTCAGGTTA TCCTACATTA CGGATAGAGA AGAATGACCT TAAAAGTGTA 720

ACCCTGATGG AAGCAAAAGC TAAAGTGAAA GACATAGCAA TCTCTAGGGA GAGGATAACA 780

CTAAAAGATG TTCTTCAAGA AGGTACATTT GGGCAAATTT TTCATGGAAC TCTAATAGAA 840

GAGAAAGATC CTAGTAAAGA AAAGCAAATG TTTGTCAAAA CAGTAAAAGA TCAAGCTTCA 900

GAAGTTCAAG TGACCATGAT GTTGACAGAA AGCTGTAAAC TCAGAGGCCT TCATCACAGG 960

AATCTTCTCC CTATCACTCA TGTTTGCATA GAGGAAGGAG AAAAGCCTAT GGTGCTGTTG 1020

CCTTATATGA ATTGGGGAAA TCTTAAGCTG TTCTTACGGC AATGCAAATT AGTAGAAGCA 1080

AATAATCCGC AGGCAATTTC ACAACAAGAT CTTGTACATA TGGCTATTCA GATCGCCTGT 1140

GGAATGAGCT ACTTGGCCCG CAGAGAGGTC ATTCATAAAG ACCTGGCTGC TAGAAACTGT 1200

GTCATTGATG ATGCACTTCA GGTAAAGATT ACAGACAATG CCCTGTCCAG AGACCTCTTT 1260

CCCATGGATT ATCATTGCCT TGGAGACAAT GAAAACAGAC CAGTGCGGTG GATGGCTCTT 1320

GAAAGCTTAG TCAACAATGA ATTTTCTGGT GCTAGTGATG TGTGGTCTTT TGGAGTGACC 1380

TTATGGGAAT TGATGACTTT GGGACAAACA CCTTATGTAG ATATAGACCC CTTTGAGATG 1440

GCAGCGTATC TAAAAGATGG ATACAGAATA GCTCAGCCTA TCAACTGCCC TGATGAATTA 1500

TTTGCTGTGA TGGCTTGTTG TTGGGCACTA GATCCTGAGG AGAGACCTAA ATTCCAGCAG 1560

CTGGTACAAT GCCTCACTGA ATTCCATGCA GCATTGGGAG CCTATGTTTG A 1611

Domain Profile

S: 1     lrlkellqeGtfGriyrGkledekdtnkekavlvktvkdqaseiqvalllqealllygvs  60

         ++lk++lqeGtfG+i++G+l +ekd++kek+++vktvkdqase+qv+++l+e+++l+g++

Q: 259   ITLKDVLQEGTFGQIFHGTLIEEKDPSKEKQMFVKTVKDQASEVQVTMMLTESCKLRGLH  318

         6799********************************************************

S: 61    hrnilsvllvsieeaekPlvvypalnkgnlkkflricklkdkekaqalstkqlvelaiqi  120

         hrn+l++++v+iee ekP+v++p++n+gnlk flr+ckl++++++qa+s+++lv++aiqi

Q: 319   HRNLLPITHVCIEEGEKPMVLLPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQI  378

         ************************************************************

S: 121   asalaylhkrevvhkdiaarncviddelqvkltdsalsrdlfPadydclGdnenrPlkWl  180

         a++++yl++rev+hkd+aarncvidd lqvk+td+alsrdlfP+dy+clGdnenrP++W+

Q: 379   ACGMSYLARREVIHKDLAARNCVIDDALQVKITDNALSRDLFPMDYHCLGDNENRPVRWM  438

         ************************************************************

S: 181   slealqkeeyssasdvWalGvllWelvtlgksPyaeidpfeleaylkdGyrlaqPvncPd  240

         +le+l+++e+s asdvW++Gv+lWel+tlg++Py++idpfe++aylkdGyr+aqP+ncPd

Q: 439   ALESLVNNEFSGASDVWSFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPD  498

         ************************************************************

S: 241   elftvmaccWallpeerPsfeqlvscl  267

         elf+vmaccWal+peerP+f+qlv+cl

Q: 499   ELFAVMACCWALDPEERPKFQQLVQCL  525

         **************************8

Domain Sequence
(FASTA)

ITLKDVLQEG TFGQIFHGTL IEEKDPSKEK QMFVKTVKDQ ASEVQVTMML TESCKLRGLH 60

HRNLLPITHV CIEEGEKPMV LLPYMNWGNL KLFLRQCKLV EANNPQAISQ QDLVHMAIQI 120

ACGMSYLARR EVIHKDLAAR NCVIDDALQV KITDNALSRD LFPMDYHCLG DNENRPVRWM 180

ALESLVNNEF SGASDVWSFG VTLWELMTLG QTPYVDIDPF EMAAYLKDGY RIAQPINCPD 240

ELFAVMACCW ALDPEERPKF QQLVQCL 267

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005886	; C:plasma membrane
GO:0005524	; F:ATP binding
GO:0004713	; F:protein tyrosine kinase activity
GO:0042813	; F:Wnt-activated receptor activity
GO:0050919	; P:negative chemotaxis
GO:0043410	; P:positive regulation of MAPK cascade
GO:0016055	; P:Wnt receptor signaling pathway

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.
IPR003306	; WIF.

Pfam

PF07714	; Pkinase_Tyr; 1.
PF02019	; WIF; 1.

SMARTs

SM00219

; TyrKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.
PS50814	; WIF; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013