EKS-ANC-00310

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00310

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	326.7	9.9E-98	17	291	275

Status

Unreviewed

Ensembl Protein

ENSACAP00000009761

UniProt Accession

G1KJI2;

Protein Name

Protein Synonyms/Alias

Gene Name

OXSR1

Gene Synonyms/Alias

OXSR1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000009859	ENSACAP00000009761	ENSACAT00000009960

Organism

Anolis carolinensis

Functional Description

Protein Length

534

Protein Sequence
(FASTA)

ATEDSSSLPW SINKDDYELQ EVIGSGATAV VQAAYCTPKK EKVAIKRINL EKCQTSMDEL 60

LKEIQAMSQC HHPNIVSYYT SFVVKDELWL VMKLLSGGSV LDVIKHIVAK GEHKNGVLDE 120

PVIATILREV LEGLEYLHKN GQIHRDVKAG NILFGEDGSV QIADFGVSAF LATGGDITRN 180

KVRKTFVGTP CWMAPEVMEQ VRGYDFKADI WSFGITAIEL ATGAAPYHKY PPMKVLMLTL 240

QNDPPSLETG VQDKDMLKKY GKSFRKMISS CLQKDPEKRP TAAELLRHKF FQKAKNKEFL 300

QEKMLQRAPT ITERAKKVRR VPGSSGRLHK TEDGGWEWSD DELDEESEEG KAAISQLRSP 360

RVKESLQNSE LFPSAEPTGP LLNVPAQIPA QLPQPAGQAP TQPSPAAPLP ASQAPPAAPP 420

AAQAPPAPAA APAQEEPKVP ISLVLRLRNS KKELNDIRFE FTPGRDTADG VSQELISAGL 480

VDGRDLVIVA ANLQKIVEEP QTNRSVTFKL ASGVEGSDIP DDSKLIGFAQ LSIN 534

Nucleotide Sequence
(FASTA)

GCTACTGAGG ACTCCAGCTC TTTGCCTTGG TCCATCAACA AGGATGACTA TGAGCTGCAG 60

GAGGTGATTG GGAGCGGAGC CACAGCCGTT GTCCAAGCAG CCTATTGTAC GCCGAAGAAA 120

GAGAAGGTGG CCATTAAACG GATCAACCTT GAGAAATGTC AGACCAGCAT GGATGAGCTC 180

CTGAAAGAAA TTCAAGCCAT GAGTCAGTGC CATCATCCAA ACATCGTTTC TTACTATACC 240

TCCTTTGTAG TGAAAGATGA ACTTTGGCTA GTGATGAAGC TCCTCAGTGG AGGTTCTGTT 300

CTGGATGTTA TTAAACACAT TGTGGCAAAA GGGGAACATA AGAACGGAGT CTTGGATGAA 360

CCGGTAATAG CTACAATCCT GAGGGAAGTG TTGGAAGGAC TGGAATACTT GCATAAAAAC 420

GGGCAAATCC ACAGGGACGT GAAAGCTGGA AATATTCTTT TCGGAGAAGA TGGCTCTGTT 480

CAGATTGCAG ATTTTGGTGT TAGTGCTTTT TTAGCCACTG GTGGAGACAT CACTCGAAAC 540

AAAGTGAGGA AAACCTTTGT GGGCACACCT TGCTGGATGG CACCTGAAGT GATGGAGCAG 600

GTCAGAGGCT ACGATTTCAA AGCAGACATC TGGAGTTTTG GGATCACGGC AATTGAGCTG 660

GCGACAGGAG CGGCTCCTTA TCACAAATAT CCCCCTATGA AGGTCTTAAT GTTAACGCTG 720

CAAAATGACC CACCTTCACT GGAGACAGGT GTACAAGACA AGGACATGTT GAAAAAGTAT 780

GGAAAATCAT TCAGGAAGAT GATCTCATCA TGCCTGCAAA AAGACCCCGA GAAAAGACCA 840

ACGGCAGCTG AACTTCTAAG ACATAAATTT TTCCAGAAAG CAAAGAATAA AGAATTTTTA 900

CAAGAAAAAA TGCTGCAAAG AGCACCAACA ATCACTGAAA GAGCCAAAAA GGTCCGGAGA 960

GTCCCTGGTT CCAGCGGTCG CCTTCATAAG ACGGAAGATG GAGGCTGGGA ATGGAGCGAC 1020

GATGAGTTAG ATGAAGAGAG TGAAGAAGGC AAAGCCGCCA TTTCACAGCT CAGGTCTCCC 1080

AGAGTGAAAG AATCATTACA GAATTCAGAG CTCTTCCCGT CAGCTGAGCC TACAGGTCCG 1140

TTGCTCAATG TCCCGGCCCA AATTCCTGCT CAACTACCTC AGCCTGCAGG CCAAGCCCCC 1200

ACACAACCGT CTCCAGCTGC CCCTCTTCCA GCTTCTCAGG CACCTCCGGC GGCTCCTCCA 1260

GCAGCACAGG CACCTCCTGC CCCTGCTGCA GCCCCAGCAC AAGAGGAACC GAAAGTCCCC 1320

ATCAGCCTTG TTTTAAGGTT AAGGAATTCA AAAAAAGAAC TCAATGACAT TCGATTTGAA 1380

TTCACGCCAG GAAGAGATAC GGCTGATGGG GTCTCCCAGG AACTCATCTC AGCAGGCCTT 1440

GTGGATGGAA GAGACTTAGT AATAGTTGCC GCCAACTTAC AAAAAATTGT GGAAGAGCCC 1500

CAGACGAATC GATCTGTCAC TTTCAAACTG GCGTCTGGTG TCGAAGGCTC CGACATCCCC 1560

GATGACAGCA AGCTCATTGG GTTTGCACAA CTCAGCATCA ATTAA 1605

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq.ekleelqkeisvlkklkhpniv  59

         yel+e+ig+Ga++ v++a++++++e+vaik+inlek+ ++++el kei+++++++hpniv

Q: 17    YELQEVIGSGATAVVQAAYCTPKKEKVAIKRINLEKCqTSMDELLKEIQAMSQCHHPNIV  76

         99***********************************8899*******************

S: 60    eylesflkeeelwlvmeylagGslsdlvk......eelkselkEeqiayilrevlkaLey  113

         +y++sf++++elwlvm++l+gGs+ d++k      e+++  l+E  ia+ilrevl++Ley

Q: 77    SYYTSFVVKDELWLVMKLLSGGSVLDVIKhivakgEHKNGVLDEPVIATILREVLEGLEY  136

         *****************************9**999999**********************

S: 114   lHskkviHrdikakniLlteegeVkLsdfgvaaqlek....trkk.rktvvgtpywmAPE  168

         lH++++iHrd+ka+niL+ e+g+V+++dfgv+a l++    tr+k rkt+vgtp+wmAPE

Q: 137   LHKNGQIHRDVKAGNILFGEDGSVQIADFGVSAFLATggdiTRNKvRKTFVGTPCWMAPE  196

         ***********************************99999988899**************

S: 169   viaqeekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklksk.....  223

         v++q  +gYd kaDiws+GItaiela+g++P+++++p+k+l+++l+n+pp+l++

Q: 197   VMEQ-VRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGvqdkd  255

         ***5.9**********************************************77777778

S: 224   ..kkfskefkefvekclqknpekRpsasellkhkFl  257

           kk++k+f++++++clqk+pekRp+a+ell+hkF+

Q: 256   mlKKYGKSFRKMISSCLQKDPEKRPTAAELLRHKFF  291

         8899*******************************7

Domain Sequence
(FASTA)

YELQEVIGSG ATAVVQAAYC TPKKEKVAIK RINLEKCQTS MDELLKEIQA MSQCHHPNIV 60

SYYTSFVVKD ELWLVMKLLS GGSVLDVIKH IVAKGEHKNG VLDEPVIATI LREVLEGLEY 120

LHKNGQIHRD VKAGNILFGE DGSVQIADFG VSAFLATGGD ITRNKVRKTF VGTPCWMAPE 180

VMEQVRGYDF KADIWSFGIT AIELATGAAP YHKYPPMKVL MLTLQNDPPS LETGVQDKDM 240

LKKYGKSFRK MISSCLQKDP EKRPTAAELL RHKFF 275

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007243	; P:intracellular protein kinase cascade
GO:0006979	; P:response to oxidative stress

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR024678	; Kinase_OSR1/WNK_CCT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF12202	; OSR1_C; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013