EKS-ANC-00274

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00274

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	351.5	3.1E-105	203	498	296

Status

Unreviewed

Ensembl Protein

ENSACAP00000009759

UniProt Accession

G1KJI1;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100556560

Gene Synonyms/Alias

LOC100556560;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000009909	ENSACAP00000009759	ENSACAT00000009958

Organism

Anolis carolinensis

Functional Description

Protein Length

534

Protein Sequence
(FASTA)

VCKWCDITYP VCEDQVCYSN CGLSSYCEKP EEICVSIWKQ DNESVRVSTL CHNPQMPVEN 60

VMIPKYNTSQ CVMVRQHNED GIFYICGCVD EQECNDKLIF ENHTNVSMPS FLSKEIIPVA 120

AISLLPPLLV AIVIIVTFYL CRTHRQRRRS KEWAQNQTQH HTLPESSRAT GYEGISSVYV 180

DNHSAVHSAC ASNIDYGTEL LPIELDARVG KGQFAEVWRA KLKRASSSDQ YETVAVKIFP 240

CEEYASWRNE SQIFWDANFK HVDILQFLAA EERHLGLQKE YWLITAYHSQ GNLKDYLSRN 300

ILSWRDLQKI AGSIVNGVAH LHSDYTPCGH PKIPIAHRDI KSTNILMKSG QECVLCDFGI 360

ALRLDPSLTV EEFANSGQVG TARYMAPEVL ESRVNLEDLE SFKQMDVYSM ALVLWEIASR 420

CDVIGEVKSY ELPFQAKIRE QLCMEVMRDI VLHGRGRPEI PSNWLVHQGM HFFCDTITEC 480

WDHDPEARLT AHCVAERLNL IAQTDCDDIL NNNSIDNETN KMGCPREESQ NSNK 534

Nucleotide Sequence
(FASTA)

GTTTGTAAGT GGTGTGATAT TACATATCCA GTATGTGAAG ATCAGGTGTG TTACAGCAAC 60

TGTGGTTTAA GCTCCTATTG TGAAAAGCCC GAAGAAATAT GTGTGTCTAT ATGGAAACAA 120

GACAACGAAA GTGTTAGAGT GAGCACGCTT TGTCACAACC CACAAATGCC AGTTGAAAAT 180

GTCATGATTC CCAAGTATAA CACCTCCCAG TGTGTGATGG TCCGTCAGCA CAATGAAGAT 240

GGGATATTTT ACATATGTGG CTGTGTGGAT GAGCAGGAGT GCAACGACAA ACTTATATTT 300

GAAAATCATA CAAATGTGTC TATGCCATCG TTTTTGAGTA AGGAGATCAT TCCTGTCGCA 360

GCCATCAGTC TGTTGCCTCC ACTGCTTGTT GCCATCGTGA TAATAGTGAC GTTTTACCTC 420

TGCCGAACCC ATAGACAGAG AAGAAGATCC AAGGAATGGG CACAGAATCA AACACAGCAC 480

CATACCTTGC CTGAGTCAAG CAGAGCCACT GGCTATGAAG GGATCTCATC TGTCTATGTA 540

GACAACCACT CTGCTGTACA CTCGGCTTGT GCCAGCAATA TTGACTATGG CACTGAACTT 600

TTGCCCATTG AGCTCGATGC GAGAGTGGGT AAAGGGCAGT TTGCAGAAGT GTGGAGAGCA 660

AAACTCAAGC GTGCCTCTTC AAGCGACCAG TATGAAACTG TGGCAGTCAA GATTTTTCCT 720

TGTGAGGAGT ATGCTTCATG GAGAAATGAA AGCCAGATCT TTTGGGATGC CAACTTTAAA 780

CATGTTGACA TCCTTCAGTT CCTCGCAGCA GAGGAGAGAC ATTTGGGCCT CCAGAAGGAA 840

TATTGGCTCA TCACGGCCTA TCACAGTCAG GGAAACCTCA AGGATTATTT GTCAAGGAAT 900

ATTCTGAGTT GGAGAGACTT GCAAAAGATA GCCGGGTCCA TTGTGAATGG CGTGGCCCAC 960

TTACACAGCG ACTATACTCC TTGTGGCCAT CCAAAGATCC CCATTGCCCA TCGGGACATC 1020

AAAAGTACAA ACATCCTGAT GAAGAGTGGT CAGGAATGTG TACTCTGTGA TTTTGGAATT 1080

GCTTTGAGGC TGGATCCATC ATTGACGGTG GAAGAGTTTG CTAACAGCGG ACAGGTGGGT 1140

ACAGCCAGAT ATATGGCTCC TGAGGTCTTG GAATCCAGAG TGAATCTTGA AGATCTGGAA 1200

TCCTTCAAAC AAATGGATGT CTACTCCATG GCTTTGGTTT TATGGGAGAT AGCCTCCAGG 1260

TGTGATGTTA TCGGAGAGGT TAAGAGTTAT GAGCTACCAT TTCAAGCAAA GATCCGGGAA 1320

CAGCTGTGCA TGGAAGTAAT GAGAGATATT GTACTGCATG GCCGAGGGCG TCCTGAGATA 1380

CCAAGTAACT GGCTGGTACA TCAGGGAATG CATTTCTTCT GTGATACTAT TACAGAATGC 1440

TGGGATCATG ACCCTGAAGC TAGGCTCACA GCACACTGTG TAGCAGAGCG GCTTAACCTG 1500

ATAGCACAGA CAGATTGCGA TGACATCCTC AACAACAACA GCATTGACAA TGAGACCAAC 1560

AAAATGGGAT GTCCAAGAGA AGAAAGTCAA AATAGCAATA AG 1602

Domain Profile

S: 1     lklleligkGrygeVwkaklrg.......eevAvKifstedeaswkrEkeiyqtvllrhe  53

         ++l   +gkG+++eVw+akl+        e+vAvKif+ e+ asw++E++i+   + +h

Q: 203   IELDARVGKGQFAEVWRAKLKRasssdqyETVAVKIFPCEEYASWRNESQIFWDANFKHV  262

         567889**************999999999*******************************

S: 54    nilqfiaadkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLH  113

         +ilqf+aa++++ ++++e++l+t+yh +g+L dyL+r++l++++l ++a s+++G+ahLH

Q: 263   DILQFLAAEERHLGLQKEYWLITAYHSQGNLKDYLSRNILSWRDLQKIAGSIVNGVAHLH  322

         ************************************************************

S: 114   eeivgtkgkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGt  173

         ++  + +g+ K  iaHRD+ks Nil+k+ + c+++D+G+al+l+ + ++++ a++ qvGt

Q: 323   SD-YTPCGHPKIPIAHRDIKSTNILMKSGQECVLCDFGIALRLDPSLTVEEFANSGQVGT  381

         **.678899***************************************************

S: 174   kRYmaPEvleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgs  233

          RYmaPEvle+++nl+d+e+fk++DvYs++LvlWE+asRc+   +ev+ y+lpf++++++

Q: 382   ARYMAPEVLESRVNLEDLESFKQMDVYSMALVLWEIASRCDV-IGEVKSYELPFQAKIRE  440

         *****************************************9.999**************

S: 234   dPsleemkevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         + ++e m+++v++ + rP+ip++w  ++ ++ ++++++ecWd+dpeaRlta++v++rl

Q: 441   QLCMEVMRDIVLHGRGRPEIPSNWLVHQGMHFFCDTITECWDHDPEARLTAHCVAERL  498

         ******************************************************9986

Domain Sequence
(FASTA)

IELDARVGKG QFAEVWRAKL KRASSSDQYE TVAVKIFPCE EYASWRNESQ IFWDANFKHV 60

DILQFLAAEE RHLGLQKEYW LITAYHSQGN LKDYLSRNIL SWRDLQKIAG SIVNGVAHLH 120

SDYTPCGHPK IPIAHRDIKS TNILMKSGQE CVLCDFGIAL RLDPSLTVEE FANSGQVGTA 180

RYMAPEVLES RVNLEDLESF KQMDVYSMAL VLWEIASRCD VIGEVKSYEL PFQAKIREQL 240

CMEVMRDIVL HGRGRPEIPS NWLVHQGMHF FCDTITECWD HDPEARLTAH CVAERL 296

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Danio rerio"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Latimeria chalumnae"; ?>Meleagris gallopavo"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Pelodiscus sinensis"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>

Gene Ontology

GO:0016021	; C:integral to membrane
GO:0043235	; C:receptor complex
GO:0005524	; F:ATP binding
GO:0046872	; F:metal ion binding
GO:0004702	; F:receptor signaling protein serine/threonine kinase activity
GO:0005026	; F:transforming growth factor beta receptor activity, type II
GO:0023014	; P:signal transduction by phosphorylation
GO:0007179	; P:transforming growth factor beta receptor signaling pathway

KEGG

InterPros

IPR000333	; Activin_II/TGFBeta-II_recpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR017194	; Transform_growth_fac-b_typ-2.
IPR015013	; Transforming_GF_b_rcpt_2_ecto.

Pfam

PF08917	; ecTbetaR2; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00653

; ACTIVIN2R.

Created Date

20-Feb-2013