EKS-ANC-00414

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00414

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	538.7	2.4E-162	98	355	258

Status

Unreviewed

Ensembl Protein

ENSACAP00000010101

UniProt Accession

H9GG89;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK1

Gene Synonyms/Alias

SGK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000010226	ENSACAP00000010101	ENSACAT00000010308

Organism

Anolis carolinensis

Functional Description

Protein Length

431

Protein Sequence
(FASTA)

MTIKTDTSGS VLTYSKMRGM VAILIAFMKQ RRMGLNDFIQ KIATNSYACK HPEVQSILKI 60

SQPQEPELMN ANPSPPPSPS QQINLGPSSN PHAKPSDFHF LKVIGKGSFG KVLLARHKAE 120

EQFYAVKVLQ KKAILKKKEE KHIMSERNVL LKNVKHPFLV GLHFSFQTAD KLYFVLDYIN 180

GGELFYHLQR ERCFLEPRAR FYAAEIGSAL GYLHSLNIVY RDLKPENILL DSQGHIVLTD 240

FGLCKENIEH NGTTSTFCGT PEYLAPEVLH KQPYDRTVDW WCLGAVLYEM LYGLPPFYSR 300

NTAEMYDNIL NKPLQLKPNI TNSARHLLEG LLQKDRTKRL GAKEDFMEIK NHIFFSPINW 360

DDLINKKITP PFNPNVSGPS DLRHFDPEFT EEPVPNSIGQ ASDSILITAS VKEAAEAFLG 420

FSYAPPMDSF L 431

Nucleotide Sequence
(FASTA)

ATGACGATCA AAACCGACAC GTCGGGGTCC GTTCTCACTT ATTCAAAGAT GCGAGGAATG 60

GTGGCCATAC TGATTGCTTT CATGAAGCAG AGGAGGATGG GGCTGAACGA CTTCATCCAG 120

AAAATCGCCA CCAACTCCTA TGCGTGCAAA CACCCTGAAG TTCAATCTAT TTTGAAGATC 180

TCTCAGCCTC AAGAGCCTGA ACTTATGAAT GCCAATCCAT CACCTCCCCC CAGTCCATCC 240

CAGCAGATCA ACCTTGGACC CTCATCCAAC CCACATGCTA AACCATCAGA TTTCCATTTC 300

CTGAAGGTTA TTGGAAAAGG CAGTTTTGGG AAGGTTCTTC TTGCAAGGCA CAAGGCAGAA 360

GAACAATTCT ATGCAGTTAA AGTCCTCCAG AAGAAAGCAA TCCTGAAAAA GAAAGAGGAG 420

AAACACATCA TGTCAGAACG CAATGTCCTG CTGAAGAATG TCAAGCATCC TTTCTTGGTT 480

GGGCTCCACT TCTCTTTCCA GACTGCTGAC AAACTGTACT TTGTTCTAGA CTACATCAAC 540

GGGGGTGAGT TGTTCTACCA TCTCCAAAGG GAACGTTGTT TCCTGGAACC AAGAGCTCGT 600

TTTTATGCTG CTGAAATAGG CAGTGCACTG GGCTACCTGC ATTCTCTGAA CATTGTTTAT 660

CGAGACTTGA AGCCAGAGAA TATTTTGCTG GATTCTCAGG GCCACATTGT TTTGACAGAC 720

TTTGGACTCT GCAAAGAGAA CATAGAGCAC AATGGCACAA CTTCCACGTT TTGTGGCACT 780

CCTGAGTACC TTGCCCCTGA AGTCCTACAT AAGCAACCTT ATGATCGAAC TGTGGACTGG 840

TGGTGCCTTG GAGCAGTCCT GTATGAAATG CTTTATGGAC TGCCCCCCTT CTACAGTAGA 900

AACACAGCAG AAATGTATGA CAACATTCTG AACAAACCTC TACAGCTGAA GCCAAATATC 960

ACTAACTCCG CTAGGCATCT TTTGGAAGGT CTTTTGCAGA AGGACAGGAC CAAGAGGCTA 1020

GGAGCCAAGG AGGACTTTAT GGAGATTAAG AATCACATCT TCTTCTCCCC AATTAACTGG 1080

GATGATCTCA TTAATAAGAA GATTACTCCC CCCTTCAACC CAAATGTGAG TGGCCCTAGT 1140

GACCTACGGC ACTTTGATCC TGAATTTACA GAGGAGCCGG TCCCAAACTC CATTGGCCAG 1200

GCTTCTGACA GTATCCTCAT CACTGCCAGC GTCAAGGAGG CTGCCGAAGC TTTTCTGGGC 1260

TTCTCCTATG CTCCTCCTAT GGATTCTTTC CTGTGA 1296

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         f+flkvigkgsfgkvlla++ka+e+fyavkvlqkkailkkkeekhim+ernvllknvkhp

Q: 98    FHFLKVIGKGSFGKVLLARHKAEEQFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP  157

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglh+sfqta+klyfvldy+nggelf+hlqrer+fleprarfyaaei salgylhsln

Q: 158   FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIGSALGYLHSLN  217

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds+gh+vltdfglcke+ie++ ttstfcgtpeylapevl+k+pydrt

Q: 218   IVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRT  277

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfysr++aemydnilnkplqlkp+i+++a++lle+ll+kdr+

Q: 278   VDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRT  337

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         krlgakedf+eiknh+ff

Q: 338   KRLGAKEDFMEIKNHIFF  355

         *****************9

Domain Sequence
(FASTA)

FHFLKVIGKG SFGKVLLARH KAEEQFYAVK VLQKKAILKK KEEKHIMSER NVLLKNVKHP 60

FLVGLHFSFQ TADKLYFVLD YINGGELFYH LQRERCFLEP RARFYAAEIG SALGYLHSLN 120

IVYRDLKPEN ILLDSQGHIV LTDFGLCKEN IEHNGTTSTF CGTPEYLAPE VLHKQPYDRT 180

VDWWCLGAVL YEMLYGLPPF YSRNTAEMYD NILNKPLQLK PNITNSARHL LEGLLQKDRT 240

KRLGAKEDFM EIKNHIFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

acs:100565714

;

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013