EKS-ANC-00241

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00241

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	315.7	1.8E-94	3	237	235

Status

Unreviewed

Ensembl Protein

ENSACAP00000010079

UniProt Accession

G1KJX3;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKAA1

Gene Synonyms/Alias

PRKAA1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000010236	ENSACAP00000010079	ENSACAT00000010286

Organism

Anolis carolinensis

Functional Description

Protein Length

516

Protein Sequence
(FASTA)

VGKHELTGHK VAVKILNRQK IRSLDVVGKI RREIQNLKLF RHPHIIKLYQ VISTPSDIFM 60

VMEYVSGGEL FDYICKNGRL DEKESRRLFQ QILSGVDYCH RHMVVHRDLK PENVLLDAHM 120

NAKIADFGLS NMMSDGEFLR TSCGSPNYAA PEVISGRLYA GPEVDIWSSG VILYALLCGT 180

LPFDDDHVPT LFKKICDGIF YTPQYLNPAV ISLLKHMLQV DPMKRATIRD IREHDWFKLD 240

LPKYLFPEDP SYSSTMIDDE ALKEVCEKFE CTEEEVLGCL YNRNHQDPLA VAYHLIIDNR 300

RIMNEAKDFY LATSPPDSFL DDHFSRPHPE RVPFLVAELP RQRHTLDELN PQKSKHQGVR 360

RAKWHLGIRS QSRPNDIMAE VCRAIKQLDY EWKVVNPYYL RVRRKNPVTG TYSKMSLQLY 420

QVDSRTYLLD FRSIDDEINE VKSGTATPQR SGSVTNYKSC QKDSDTDAQG RSSDMSLTSS 480

VTSSLDSSSA ELTPRSGSHT IEFFEMCANL IKILAQ 516

Nucleotide Sequence
(FASTA)

GTTGGCAAGC ATGAGCTGAC TGGGCACAAA GTAGCGGTTA AGATCTTGAA CAGACAGAAG 60

ATTCGCAGTC TTGACGTCGT GGGTAAAATC CGCAGAGAAA TTCAGAATCT GAAGCTTTTT 120

CGGCATCCAC ACATAATTAA GCTGTACCAG GTTATCAGCA CACCCTCTGA CATTTTCATG 180

GTTATGGAAT ATGTTTCAGG AGGTGAATTG TTTGATTACA TCTGTAAAAA TGGAAGGCTT 240

GACGAAAAGG AGAGTAGACG CCTCTTCCAG CAAATCCTTT CAGGTGTGGA TTATTGCCAT 300

AGGCACATGG TAGTTCACAG AGACTTGAAA CCTGAAAATG TACTACTCGA TGCACACATG 360

AATGCCAAGA TTGCTGATTT TGGCCTTTCA AATATGATGT CAGATGGAGA ATTTTTGAGA 420

ACAAGCTGTG GCTCTCCTAA TTATGCTGCT CCAGAAGTAA TTTCCGGAAG ATTATATGCA 480

GGCCCAGAAG TGGATATCTG GAGCAGTGGA GTTATTCTTT ATGCTCTGTT ATGTGGGACC 540

CTTCCGTTTG ACGATGATCA TGTGCCAACA CTTTTTAAGA AAATATGTGA TGGTATATTT 600

TATACTCCTC AGTACCTGAA TCCAGCAGTA ATTAGCCTTT TGAAACACAT GCTGCAGGTG 660

GATCCTATGA AGAGAGCTAC AATAAGAGAT ATAAGGGAAC ATGACTGGTT CAAGCTCGAC 720

CTCCCCAAGT ACCTCTTTCC TGAAGACCCA TCGTACAGTT CAACCATGAT TGATGATGAA 780

GCCTTAAAAG AGGTCTGTGA GAAGTTTGAA TGCACAGAGG AGGAAGTACT TGGCTGCTTG 840

TATAATCGAA ATCATCAGGA TCCTTTAGCC GTTGCCTACC ACTTGATTAT AGATAACAGG 900

AGAATAATGA ATGAAGCTAA AGACTTTTAC TTGGCAACAA GCCCACCAGA TTCCTTTCTT 960

GACGATCACT TCTCCCGCCC CCACCCCGAA AGAGTGCCAT TTTTAGTTGC TGAATTACCA 1020

AGGCAGCGGC ATACGCTTGA TGAGCTAAAC CCACAGAAGT CCAAACACCA AGGAGTCAGA 1080

AGAGCAAAGT GGCATTTGGG AATTCGGAGT CAGAGTCGAC CAAATGACAT AATGGCAGAA 1140

GTTTGTCGAG CAATCAAACA GTTGGATTAT GAATGGAAGG TTGTAAATCC ATACTATTTG 1200

CGTGTTCGAA GGAAGAATCC AGTGACTGGC ACTTATTCCA AAATGAGTCT ACAGTTATAC 1260

CAGGTGGACA GTAGAACTTA TCTATTGGAT TTCCGTAGCA TTGATGATGA AATTAATGAA 1320

GTCAAATCTG GGACTGCCAC TCCCCAGAGG TCAGGCTCTG TGACAAACTA CAAATCTTGT 1380

CAGAAAGATT CGGACACTGA TGCTCAAGGA AGATCCTCTG ATATGTCTCT TACCTCCTCT 1440

GTGACCTCTT CCCTCGACTC ATCTTCAGCT GAGTTGACCC CAAGATCAGG GAGCCACACA 1500

ATAGAATTTT TTGAAATGTG TGCGAATCTT ATTAAAATAC TTGCGCAATG A 1551

Domain Profile

S: 19    khketkekvavKiikkkkl.seeslekikrEieilkklkhpniikllevietkkklylvl  77

         kh++t++kvavKi++++k+ s + + ki+rEi+ lk ++hp+iikl++vi+t +++++v+

Q: 3     KHELTGHKVAVKILNRQKIrSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVM  62

         7999**************96667788**********************************

S: 78    eyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgivHrDlKpeNllldkkeni  137

         ey+sggeLfdyi ++grl+eke+r+lf+q++s+v+Y+h++ +vHrDlKpeN+lld+++n

Q: 63    EYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNA  122

         ************************************************************

S: 138   kiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvDvWslGvvLyalvtgklP  197

         kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+vD+Ws Gv+Lyal++g+lP

Q: 123   KIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLP  182

         ************************************************************

S: 198   fdeenlkellekilkgkleipkklskelesLlrklLvvdpekRatieeilkhewl  252

         fd++++ +l++ki +g + +p++l++ ++sLl+++L+vdp kRati++i++h w+

Q: 183   FDDDHVPTLFKKICDGIFYTPQYLNPAVISLLKHMLQVDPMKRATIRDIREHDWF  237

         ******************************************************7

Domain Sequence
(FASTA)

KHELTGHKVA VKILNRQKIR SLDVVGKIRR EIQNLKLFRH PHIIKLYQVI STPSDIFMVM 60

EYVSGGELFD YICKNGRLDE KESRRLFQQI LSGVDYCHRH MVVHRDLKPE NVLLDAHMNA 120

KIADFGLSNM MSDGEFLRTS CGSPNYAAPE VISGRLYAGP EVDIWSSGVI LYALLCGTLP 180

FDDDHVPTLF KKICDGIFYT PQYLNPAVIS LLKHMLQVDP MKRATIRDIR EHDWF 235

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0004679	; F:AMP-activated protein kinase activity
GO:0005524	; F:ATP binding
GO:0003682	; F:chromatin binding
GO:0035174	; F:histone serine kinase activity
GO:0042149	; P:cellular response to glucose starvation
GO:0019395	; P:fatty acid oxidation
GO:0042593	; P:glucose homeostasis
GO:0006006	; P:glucose metabolic process
GO:0008610	; P:lipid biosynthetic process
GO:0043066	; P:negative regulation of apoptotic process
GO:0050995	; P:negative regulation of lipid catabolic process
GO:0032007	; P:negative regulation of TOR signaling cascade
GO:0010508	; P:positive regulation of autophagy
GO:0042752	; P:regulation of circadian rhythm

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013