EKS-ANC-00412

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00412

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/WEE	344.4	3.6E-103	68	340	273

Status

Unreviewed

Ensembl Protein

ENSACAP00000021266

UniProt Accession

G1KL87;

Protein Name

Protein Synonyms/Alias

Gene Name

WEE2

Gene Synonyms/Alias

WEE2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000011522	ENSACAP00000011307	ENSACAT00000011544
ENSACAG00000011522	ENSACAP00000021266	ENSACAT00000023765

Organism

Anolis carolinensis

Functional Description

Protein Length

430

Protein Sequence
(FASTA)

PPSNSLVNIN PFTPDSYRQM VFHPSGKRKT RGELDDPSQK GSPMELGLPA KRFLLRESNM 60

VSRYKKEFLE LEKIGVGEFG SVYKCIKRLD GCVYAIKRSK RPLAGSSDEQ MALREVYAHA 120

VLGHHPHVVR YYSAWAEDDH MIIQNEHCNG GSLQDVLLEN LKTADYFKES ELKEILLQVS 180

MGLKYIHSSG LVHMDIKPSN IFICHKLIGL AGVEESDGED DGFASSSVVY KIGDLGHVTS 240

IATPQVEEGD CQFLANEILQ EQYCYLPKAD IFALALTVAQ AAGCGTLPAN GTMWHHIRKG 300

NLPAIPQQLS RGFIELLKLM IHPDPVMRPS ATALTKHPIL RPSLGKADQL QKQLNVERFK 360

TAMLERELKA ARLAQTFKKE QAIKRDLTLE CARPQESGTN SRLKNNKKRL VGGKNARSFS 420

FTTLQGDSSP 430

Nucleotide Sequence
(FASTA)

CCTCCCTCAA ATTCTCTGGT TAATATTAAT CCTTTTACAC CTGATTCATA TAGACAGATG 60

GTTTTCCATC CCAGTGGGAA AAGGAAAACT AGAGGAGAAT TGGATGATCC CAGCCAAAAA 120

GGGAGTCCAA TGGAGCTTGG CTTGCCAGCC AAGAGATTCC TTTTGCGTGA AAGCAACATG 180

GTTTCTCGTT ACAAGAAGGA ATTCTTGGAG CTGGAGAAAA TTGGTGTGGG GGAATTTGGT 240

TCAGTATACA AGTGCATCAA AAGGCTGGAT GGATGTGTTT ATGCCATCAA GCGCTCAAAG 300

AGGCCCCTTG CTGGATCCTC AGATGAGCAA ATGGCTTTGC GAGAAGTCTA TGCCCATGCA 360

GTGCTTGGCC ATCATCCTCA CGTGGTGCGT TACTACTCAG CTTGGGCAGA AGATGATCAC 420

ATGATTATTC AGAATGAACA CTGCAATGGT GGTAGCCTTC AAGATGTGCT TTTGGAGAAC 480

CTGAAGACAG CCGATTATTT CAAAGAATCT GAGCTGAAGG AGATCTTGCT GCAAGTCTCC 540

ATGGGGCTGA AATATATTCA CTCTTCTGGT CTAGTGCACA TGGATATCAA GCCCAGCAAT 600

ATCTTTATAT GTCACAAGCT GATTGGGCTT GCAGGAGTGG AGGAGAGTGA CGGTGAAGAT 660

GATGGCTTTG CCTCTTCTAG TGTGGTATAT AAAATTGGAG ACCTTGGACA TGTGACATCC 720

ATAGCTACAC CACAAGTGGA GGAAGGAGAC TGCCAGTTCT TGGCCAATGA AATCTTGCAA 780

GAGCAATACT GCTATCTGCC CAAGGCAGAC ATTTTTGCTC TTGCATTAAC TGTTGCTCAG 840

GCAGCAGGTT GTGGGACATT ACCTGCCAAT GGTACCATGT GGCACCACAT CCGCAAAGGC 900

AACCTTCCAG CAATCCCACA GCAGCTGTCA CGTGGCTTTA TTGAACTGCT CAAGCTTATG 960

ATTCATCCTG ACCCAGTTAT GAGGCCATCA GCCACTGCAC TAACCAAGCA TCCTATCCTT 1020

CGGCCTTCTC TTGGGAAAGC TGACCAACTT CAGAAGCAGC TAAATGTGGA GAGGTTCAAA 1080

ACTGCTATGC TGGAAAGGGA ACTGAAGGCA GCCCGTCTAG CTCAGACCTT CAAAAAGGAG 1140

CAGGCCATCA AAAGAGACCT GACTTTGGAA TGTGCCAGGC CTCAAGAATC TGGAACCAAT 1200

TCAAGGCTTA AGAACAACAA GAAACGCCTA GTGGGAGGGA AAAATGCCCG GTCATTTAGC 1260

TTTACGACTC TACAAGGTGA CTCTAGCCCT 1290

Domain Profile

S: 1     FeevekiGkGefgevfkvvkredgklyAikkskkplkglskekkalrEvtahavlgqhen  60

         F e+ekiG+Gefg+v+k++kr+dg++yAik+sk+pl+g+s+e+ alrEv+ahavlg+h++

Q: 68    FLELEKIGVGEFGSVYKCIKRLDGCVYAIKRSKRPLAGSSDEQMALREVYAHAVLGHHPH  127

         7899********************************************************

S: 61    vvryisaWeeddslyiqtElCeggsLeaalqeceakkkaleeaelkkilldlllglrylH  120

         vvry+saW+edd+++iq+E C+ggsL+++l e+ ++ ++++e+elk+ill+++ gl+y+H

Q: 128   VVRYYSAWAEDDHMIIQNEHCNGGSLQDVLLENLKTADYFKESELKEILLQVSMGLKYIH  187

         ************************************************************

S: 121   ssslvHlDikpenifi.....................tkevtlklgDlGlvtelnsedks  159

         ss lvH+Dikp+nifi                     +++v++k+gDlG+vt++    ++

Q: 188   SSGLVHMDIKPSNIFIchkliglagveesdgeddgfaSSSVVYKIGDLGHVTSI---ATP  244

         *************************************9****************...99*

S: 160   kveEGDsrylakEilqeeyskl.kaDiFslgltilevaanvelPsnGeaWhklRkgklpd  218

         +veEGD+++la+Eilqe+y  l kaDiF+l+lt++++a+  +lP nG++Wh++Rkg+lp

Q: 245   QVEEGDCQFLANEILQEQYCYLpKADIFALALTVAQAAGCGTLPANGTMWHHIRKGNLP-  303

         ***********************************************************.

S: 219   eilkelsedlrellklmlepdperRptaeellkhevl  255

          i ++ls+ + ellklm++pdp  Rp+a++l kh++l

Q: 304   AIPQQLSRGFIELLKLMIHPDPVMRPSATALTKHPIL  340

         **********************************986

Domain Sequence
(FASTA)

FLELEKIGVG EFGSVYKCIK RLDGCVYAIK RSKRPLAGSS DEQMALREVY AHAVLGHHPH 60

VVRYYSAWAE DDHMIIQNEH CNGGSLQDVL LENLKTADYF KESELKEILL QVSMGLKYIH 120

SSGLVHMDIK PSNIFICHKL IGLAGVEESD GEDDGFASSS VVYKIGDLGH VTSIATPQVE 180

EGDCQFLANE ILQEQYCYLP KADIFALALT VAQAAGCGTL PANGTMWHHI RKGNLPAIPQ 240

QLSRGFIELL KLMIHPDPVM RPSATALTKH PIL 273

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005813	; C:centrosome
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004715	; F:non-membrane spanning protein tyrosine kinase activity
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007343	; P:egg activation
GO:0007143	; P:female meiosis
GO:0035038	; P:female pronucleus assembly
GO:0007137	; P:meiotic metaphase II
GO:0007128	; P:meiotic prophase I
GO:0007067	; P:mitosis
GO:0060283	; P:negative regulation of oocyte development
GO:0060631	; P:regulation of meiosis I

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR017164	; Wee1-like_protein_kinase.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013