EKS-ANC-00203

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00203

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	313.9	6.8E-94	1	213	213

Status

Unreviewed

Ensembl Protein

ENSACAP00000011458

UniProt Accession

G1KLE0;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL5

Gene Synonyms/Alias

CDKL5;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000011708	ENSACAP00000011458	ENSACAT00000011697

Organism

Anolis carolinensis

Functional Description

Protein Length

810

Protein Sequence
(FASTA)

YMYFTYICKN MLELLEEMPN GVPPEKVKSY IYQLIKAIHW CHKNDIVHRD IKPENLLISH 60

NDILKLCDFG FARNLSEGSN ANYTEYVATR WYRSPELLLG APYGKSVDMW SVGCILGELS 120

DGQPLFPGES EIDQLFTIQK VLGPLPAEQM KLFYSNPRFH GLRFPAVNHP QSLERRYLGI 180

LSGVILDLMK KNLLKLDPAD RYLTEQCLNH PAFQTQRLLD RSPSRSTKRK PYHGDSNTLS 240

NRNQASKGSA VQSHHRSNSK DIGLQREEAL PTTESFLNGN LPVTSHSPML SKKSSNPPGS 300

GSKDLANNNV PHLLSPKEAK SKNEFDFSSD TKGSDGPGTK YLKSNSRSQH NRHSFMESSQ 360

SKTGTLQPGE RHSRHSYIDT IPQSSKSPSY RTKSKSHGAL TDSKSVGNLS EARVQVAEQN 420

NSRYFPSSCV DLNSPTTPTP PRHADSRTLL SPSGRNNRSD GTLESRRPST RHSKTMEELK 480

MPDHMDGSHS HSLSAPHESF SYGLGYTSPF SSQQRPHRHS MYVSRDRVRT KGSEGGLSVG 540

QGMAARANSL QLLSPQVQHK SLTRSGGSSR EDCTEDTNRF HLNHLDSGGV YHDQHPDDGT 600

STKENRILYN DPVPRRVGSF YRVPSPRPEG TFLDNSASNR IPSLPTESSS VTSHSKRQTA 660

FDPWKSPENA HSEQMKEKEK QGFFRSIKKK KKKSQSMPGS DNQDLLSLQK AIHSSNHPSN 720

RQKDWHSEKM AEIQSHSQPL KSLRKLLHLS SSSNHSIPSD PRFQPLQSQQ AKTSFSEVRI 780

HPISQASGTS SSSNMRQESQ SKGRTSLQIP 810

Nucleotide Sequence
(FASTA)

TATATGTATT TCACTTATAT TTGTAAAAAT ATGCTTGAAC TGCTGGAAGA AATGCCAAAT 60

GGAGTCCCAC CTGAAAAAGT AAAAAGTTAT ATATACCAGC TAATTAAAGC AATTCATTGG 120

TGTCATAAGA ATGATATTGT TCATAGAGAT ATCAAGCCAG AGAATCTCTT AATAAGCCAC 180

AATGATATAT TAAAACTGTG TGACTTTGGT TTTGCACGGA ATTTGTCAGA AGGAAGCAAT 240

GCTAATTACA CAGAATATGT GGCCACCAGG TGGTATCGTT CTCCTGAACT CTTGCTTGGA 300

GCCCCCTATG GCAAGTCTGT GGATATGTGG TCTGTAGGTT GTATTCTTGG AGAACTGAGT 360

GATGGACAAC CATTGTTTCC TGGAGAAAGT GAAATTGACC AACTTTTTAC AATCCAGAAG 420

GTGCTAGGAC CACTTCCTGC AGAGCAAATG AAGCTTTTCT ACAGTAATCC CCGTTTCCAT 480

GGGCTACGGT TCCCAGCAGT TAACCATCCA CAATCTTTGG AAAGGAGATA TTTGGGAATC 540

TTAAGTGGTG TTATACTTGA CCTTATGAAG AAGAACTTGC TGAAACTGGA TCCAGCAGAT 600

CGATACTTGA CAGAGCAGTG TTTGAACCAC CCAGCATTCC AAACTCAGAG GCTCTTGGAT 660

CGATCACCGT CCAGGTCAAC TAAAAGAAAA CCTTATCATG GTGATAGCAA CACCTTATCT 720

AACAGAAATC AAGCTAGCAA AGGCAGTGCT GTGCAGTCTC ATCATAGATC AAACAGCAAA 780

GACATAGGAC TGCAAAGAGA AGAGGCTCTT CCAACAACGG AAAGCTTTCT AAATGGAAAT 840

CTTCCTGTAA CTTCACATAG TCCTATGCTT TCAAAAAAGT CAAGCAATCC TCCTGGATCT 900

GGAAGCAAGG ATCTAGCAAA TAATAATGTA CCACATCTTC TGAGTCCAAA AGAAGCAAAG 960

TCAAAAAATG AATTTGACTT TAGTTCGGAT ACCAAGGGTT CAGATGGTCC AGGTACAAAA 1020

TATCTGAAGT CAAATTCCAG ATCTCAGCAT AATCGTCATT CATTTATGGA AAGTTCCCAA 1080

AGCAAAACTG GTACACTGCA GCCAGGTGAA AGACACAGTC GTCACAGCTA TATTGATACT 1140

ATTCCTCAGT CTTCAAAAAG TCCCTCGTAT CGAACCAAAT CAAAAAGTCA CGGGGCTCTG 1200

ACGGATTCCA AATCTGTGGG TAATCTGTCT GAGGCTAGAG TTCAAGTTGC AGAACAAAAC 1260

AACAGTAGAT ACTTCCCATC CAGCTGCGTG GACTTAAACT CTCCTACCAC ACCAACACCA 1320

CCTCGCCATG CCGACAGCAG AACTTTGCTC AGTCCTTCTG GGAGAAATAA CAGAAGTGAC 1380

GGTACACTTG AATCCCGAAG GCCATCTACA AGACATTCCA AAACTATGGA GGAGCTGAAA 1440

ATGCCGGATC ACATGGATGG AAGCCATTCA CACTCTTTAT CTGCTCCCCA TGAATCTTTT 1500

TCTTATGGTC TAGGTTACAC AAGTCCCTTT TCTTCTCAAC AGCGCCCTCA TAGACATTCT 1560

ATGTATGTGA GCCGGGACAG AGTGAGGACA AAGGGCTCAG AGGGTGGCTT AAGCGTAGGG 1620

CAAGGGATGG CAGCCAGAGC AAACAGCCTA CAACTGTTAT CTCCACAGGT GCAGCATAAG 1680

TCACTTACAA GGTCTGGTGG CTCTTCACGT GAAGACTGTA CAGAAGACAC AAACAGGTTT 1740

CATTTGAATC ATTTGGATTC TGGTGGAGTT TACCATGATC AGCATCCAGA TGATGGAACA 1800

TCCACAAAAG AAAATAGAAT TCTGTATAAT GATCCGGTAC CTAGAAGAGT TGGTAGCTTT 1860

TACAGAGTCC CATCTCCACG CCCAGAAGGA ACATTCCTAG ATAACAGTGC CTCAAACAGA 1920

ATACCATCAC TACCAACAGA AAGCAGTAGT GTAACAAGCC ACTCAAAGAG ACAAACTGCT 1980

TTTGATCCCT GGAAAAGTCC TGAAAATGCT CATTCAGAAC AAATGAAGGA AAAAGAAAAG 2040

CAAGGATTTT TTAGGTCAAT AAAAAAGAAA AAAAAGAAAT CTCAATCTAT GCCTGGAAGT 2100

GACAATCAGG ATCTTTTGTC ACTACAGAAA GCTATTCATT CATCTAATCA CCCATCCAAC 2160

AGACAGAAGG ATTGGCATTC TGAGAAGATG GCAGAAATCC AAAGTCATAG TCAGCCTTTA 2220

AAGTCTCTCC GCAAGCTGTT ACACCTTTCC TCTTCCTCAA ATCATTCAAT TCCTTCTGAC 2280

CCCAGATTCC AACCCTTACA GAGCCAGCAA GCTAAGACTT CTTTTTCTGA AGTCCGAATT 2340

CATCCTATAA GTCAAGCTTC TGGTACTAGC AGCAGCAGCA ACATGCGACA AGAGTCCCAG 2400

TCAAAGGGCA GAACGAGTCT CCAGATCCCA 2430

Domain Profile

S: 74    ylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknniihrdikpenilisk  133

         y+ f y+ k++l+ le++pnGv+ e+vk+++yq++kai++chkn+i+hrdikpen+lis+

Q: 1     YMYFTYICKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISH  60

         6789********************************************************

S: 134   sgvvklcdfGfarlla.apgdvytdyvatrwyrapellvgdtkyGksvdvwaiGcllael  192

         ++++klcdfGfar+l+ +++++yt+yvatrwyr+pell+g + yGksvd+w++Gc+l el

Q: 61    NDILKLCDFGFARNLSeGSNANYTEYVATRWYRSPELLLG-APYGKSVDMWSVGCILGEL  119

         ***************98999********************.9******************

S: 193   ltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpevedleslekkyp.  251

         ++G+plfpg+s++dql++i+k+lG+l ++++k+f++n++f+G+++p+v++++sle++y

Q: 120   SDGQPLFPGESEIDQLFTIQKVLGPLPAEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLg  179

         **********************************************************98

S: 252   klnevlldllkk.clkldpaerlsceellkheyf  284

          l+ v+ldl+kk +lkldpa+r+++e++l+h+ f

Q: 180   ILSGVILDLMKKnLLKLDPADRYLTEQCLNHPAF  213

         899******975389****************987

Domain Sequence
(FASTA)

YMYFTYICKN MLELLEEMPN GVPPEKVKSY IYQLIKAIHW CHKNDIVHRD IKPENLLISH 60

NDILKLCDFG FARNLSEGSN ANYTEYVATR WYRSPELLLG APYGKSVDMW SVGCILGELS 120

DGQPLFPGES EIDQLFTIQK VLGPLPAEQM KLFYSNPRFH GLRFPAVNHP QSLERRYLGI 180

LSGVILDLMK KNLLKLDPAD RYLTEQCLNH PAF 213

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0046777	; P:protein autophosphorylation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013