EPS-ANC-00048

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ANC-00048

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP7	486.1	3.5E-146	124	460	337

Status

Unreviewed

Ensembl Protein

ENSACAP00000011524

UniProt Accession

G1KLG7;

Protein Name

Serine/threonine-protein phosphatase

Protein Synonyms/Alias

Gene Name

PPEF1

Gene Synonyms/Alias

PPEF1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000011757	ENSACAP00000011524	ENSACAT00000011764

Organism

Anolis carolinensis

Functional Description

Protein Length

654

Protein Sequence
(FASTA)

CTINSNRTQG SAESTIKAAI LIQRWYRSYV ARMQLKRQYA LSIFQSIEYA EEQAQLQLSN 60

FFTFMLNHYT ENLRRDIKSH FVSIMGDCNM ASSDPAMTEY ERRIEVPASY YGPRLSFPLT 120

AADINALLQA FKHHQQLHAR YVLQLLHETR KVLQQMPNIT HLSTSYAKEI TICGDLHGKL 180

DDLLLIFYKN GLPSEENPYI FNGDFVDRGK NSTEILIILF AFLLVYPNHL HLNRGNHEDH 240

IMNLRYGFTK EVMKKYQCHG TTILHLLQDV YSWLPLATII DNKVLILHGG ISDTTDLNFL 300

NLFQRNKLKS VLNPPKSNAG TGNDPQRAAL TEAYSHQVQT KKSNSGSHVS KLTPKEWKQV 360

VDILWSDPKH QNGCTPNKHR GGGCCFGPDV TARLLKRYNL KMLIRSHECK EEGYEISHYG 420

KHKVITIFSA SNYYEEGSNR GAYIKLNPDL IPRFVQYQVR KSTHKRTLHQ RVSTIELSAL 480

KCLREKIYIH KSELIAAFRQ YDRNGTVGKI SPSEWVSALE SVLQLDLPWR TLRSRLVCLD 540

QDGNVEYLSS FDDVEITLPI KEVQPSLVET LCRYKADLES IFNMIDKDHS GLISIDEFHQ 600

AWKLFNLHLK TAVDDESIDS LAHCIDFNKD GSIDFNEFLE AFHVVHKLEK KYSP 654

Nucleotide Sequence
(FASTA)

TGCACAATAA ACTCCAACAG AACTCAAGGA TCTGCAGAAT CAACCATCAA AGCAGCCATC 60

CTCATCCAAA GGTGGTATCG ATCTTATGTG GCTCGGATGC AGCTGAAGCG ACAATATGCT 120

CTTAGCATCT TTCAGTCAAT TGAATATGCA GAAGAACAAG CACAGCTACA GCTGTCCAAC 180

TTCTTCACAT TCATGTTGAA CCATTACACT GAAAATCTAA GAAGAGACAT TAAGTCTCAC 240

TTTGTCTCCA TTATGGGGGA TTGCAACATG GCCAGCTCAG ATCCTGCAAT GACAGAGTAT 300

GAAAGGAGAA TCGAGGTACC TGCCTCCTAC TATGGTCCTC GTCTGTCTTT CCCCCTCACA 360

GCTGCTGACA TTAATGCCCT TCTTCAAGCT TTCAAGCATC ACCAGCAGCT TCATGCTAGA 420

TATGTGCTTC AACTCTTGCA CGAGACCAGA AAGGTCCTTC AGCAGATGCC AAACATTACT 480

CATCTCTCAA CCTCTTATGC CAAGGAAATC ACCATCTGTG GTGATCTGCA TGGAAAGCTA 540

GATGATCTTT TACTGATTTT CTACAAAAAT GGTCTCCCCT CGGAAGAAAA TCCCTACATT 600

TTTAATGGTG ATTTTGTCGA CCGAGGGAAA AATTCCACAG AAATCCTTAT AATCCTGTTT 660

GCATTTCTGC TTGTCTACCC CAACCATTTA CACCTGAACA GAGGGAATCA TGAGGATCAC 720

ATCATGAATC TTAGATATGG GTTCACAAAA GAAGTTATGA AGAAGTACCA GTGCCATGGC 780

ACAACGATTT TGCATCTTCT TCAAGATGTC TACAGTTGGC TTCCTCTTGC AACTATAATA 840

GACAACAAAG TTCTAATTTT ACATGGTGGA ATCTCCGACA CAACTGATTT AAATTTCCTG 900

AATTTGTTTC AGAGAAACAA GCTGAAATCT GTACTTAACC CACCAAAATC AAATGCTGGA 960

ACAGGCAATG ATCCGCAGAG AGCTGCTCTT ACAGAAGCCT ATTCCCACCA AGTACAAACC 1020

AAGAAGTCCA ATTCTGGGTC TCACGTCTCC AAATTAACAC CAAAGGAATG GAAGCAGGTA 1080

GTAGATATTC TCTGGAGTGA TCCCAAACAT CAAAATGGCT GTACACCAAA TAAACACCGA 1140

GGTGGAGGTT GTTGCTTTGG ACCAGATGTT ACGGCCAGGT TGCTAAAACG GTACAATTTG 1200

AAAATGCTCA TCAGGTCTCA TGAATGCAAA GAGGAAGGCT ATGAGATCAG TCATTATGGA 1260

AAACATAAGG TCATCACTAT ATTTTCTGCT TCAAATTACT ATGAAGAGGG AAGTAATCGT 1320

GGTGCTTACA TCAAACTAAA TCCAGATCTG ATACCTCGTT TTGTTCAGTA TCAAGTTAGG 1380

AAATCAACAC ATAAACGGAC CCTACATCAG AGAGTTTCCA CAATTGAGCT GTCTGCCTTA 1440

AAGTGCTTGC GGGAAAAGAT TTACATACAC AAATCAGAAC TGATTGCAGC TTTTAGACAG 1500

TATGACCGGA ATGGTACAGT AGGGAAGATT TCTCCCAGTG AATGGGTTTC AGCATTGGAA 1560

TCTGTTCTAC AGCTTGACCT CCCCTGGAGG ACCTTACGTT CCAGACTGGT TTGTCTGGAT 1620

CAAGATGGAA ATGTTGAATA CCTTTCATCT TTTGATGATG TTGAAATCAC ACTGCCAATC 1680

AAAGAGGTTC AGCCATCACT GGTGGAAACC CTGTGTAGAT ACAAAGCTGA TCTGGAGAGT 1740

ATCTTTAATA TGATTGACAA AGATCACTCA GGTCTGATCT CCATTGACGA GTTCCACCAG 1800

GCATGGAAGC TCTTTAACCT ACACCTGAAA ACTGCTGTAG ATGACGAATC CATAGACAGC 1860

TTAGCCCATT GCATAGATTT CAACAAAGAT GGTAGCATTG ACTTTAATGA ATTTTTAGAA 1920

GCTTTTCATG TGGTCCACAA ATTAGAGAAG AAATACAGCC CCTAA 1965

Domain Profile

S: 1     idlllevfkkkrilhakyvlevlfeakkvlkqlpnishvstavskevtvvGdlhGklddl  60

         i+ ll++fk++++lha+yvl++l+e++kvl+q+pni+h+st+ +ke+t++GdlhGklddl

Q: 124   INALLQAFKHHQQLHARYVLQLLHETRKVLQQMPNITHLSTSYAKEITICGDLHGKLDDL  183

         5789********************************************************

S: 61    llvlkknGlPsernpyvfnGdfvdrGkrglevllvllslflvfPnavylnrGnhedkvmn  120

         ll+++knGlPse+npy+fnGdfvdrGk++ e+l++l ++ lv+Pn+++lnrGnhed++mn

Q: 184   LLIFYKNGLPSEENPYIFNGDFVDRGKNSTEILIILFAFLLVYPNHLHLNRGNHEDHIMN  243

         ************************************************************

S: 121   aryGfekevlskykrkgkrilrileevyewlPlgsivdsrvlvvhGGlsestsldllksv  180

         +ryGf+kev++ky+ +g  il++l++vy wlPl++i+d++vl++hGG+s++t+l+ l+

Q: 244   LRYGFTKEVMKKYQCHGTTILHLLQDVYSWLPLATIIDNKVLILHGGISDTTDLNFLNLF  303

         ************************************************************

S: 181   erkkrksvllpPeessrd..................lgrldtdgepreslteteweqiid  222

         +r+k ksvl pP+ ++                    + +  + g+   +lt +ew+q++d

Q: 304   QRNKLKSVLNPPKSNA-GtgndpqraalteayshqvQTKKSNSGSHVSKLTPKEWKQVVD  362

         ************9544.44899**********987656666778888999**********

S: 223   ilwsdPratnGlvPntlrGaGvyfGPdvtedflkkyelklvirsheckpegyeilhdg..  280

         ilwsdP+ +nG++Pn+ rG+G+ fGPdvt  +lk+y+lk++irsheck egyei h g

Q: 363   ILWSDPKHQNGCTPNKHRGGGCCFGPDVTARLLKRYNLKMLIRSHECKEEGYEISHYGkh  422

         ********************************************************7633

S: 281   kvvtifsasnyyeegsnkgayiklnsqltprfvqyiva  318

         kv+tifsasnyyeegsn+gayikln +l+prfvqy+v

Q: 423   KVITIFSASNYYEEGSNRGAYIKLNPDLIPRFVQYQVR  460

         7**********************************986

Domain Sequence
(FASTA)

INALLQAFKH HQQLHARYVL QLLHETRKVL QQMPNITHLS TSYAKEITIC GDLHGKLDDL 60

LLIFYKNGLP SEENPYIFNG DFVDRGKNST EILIILFAFL LVYPNHLHLN RGNHEDHIMN 120

LRYGFTKEVM KKYQCHGTTI LHLLQDVYSW LPLATIIDNK VLILHGGISD TTDLNFLNLF 180

QRNKLKSVLN PPKSNAGTGN DPQRAALTEA YSHQVQTKKS NSGSHVSKLT PKEWKQVVDI 240

LWSDPKHQNG CTPNKHRGGG CCFGPDVTAR LLKRYNLKML IRSHECKEEG YEISHYGKHK 300

VITIFSASNY YEEGSNRGAY IKLNPDLIPR FVQYQVR 337

Keyword

Calcium; Complete proteome; Hydrolase; Iron; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005509	; F:calcium ion binding
GO:0004721	; F:phosphoprotein phosphatase activity

KEGG

InterPros

IPR011992	; EF-hand-like_dom.
IPR018247	; EF_Hand_1_Ca_BS.
IPR018249	; EF_HAND_2.
IPR002048	; EF_hand_Ca-bd.
IPR000048	; IQ_motif_EF-hand-BS.
IPR004843	; Metallo_PEstase_dom.
IPR013235	; PPP_dom.
IPR006186	; Ser/Thr-sp_prot-phosphatase.

Pfam

PF00612	; IQ; 1.
PF00149	; Metallophos; 1.
PF08321	; PPP5; 1.

SMARTs

SM00054	; EFh; 3.
SM00015	; IQ; 1.
SM00156	; PP2Ac; 1.

Prosites

PS00018	; EF_HAND_1; 2.
PS50222	; EF_HAND_2; 3.
PS50096	; IQ; 1.
PS00125	; SER_THR_PHOSPHATASE; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013