EKS-ANC-00278

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00278

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	429.1	6.0E-129	525	786	262

Status

Unreviewed

Ensembl Protein

ENSACAP00000012116

UniProt Accession

H9GIT1;

Protein Name

Protein Synonyms/Alias

Gene Name

ERN2

Gene Synonyms/Alias

ERN2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000012164	ENSACAP00000012116	ENSACAT00000012361

Organism

Anolis carolinensis

Functional Description

Protein Length

919

Protein Sequence
(FASTA)

PARCSSEFQC LASLLSCLPS PNLLQSLAGS PTVVAPDSLV FVSTLDGSLH AVSKTTGDVA 60

WTLKDDPALQ APIDAGAQPA FLPDPNDGSL YVVGGKNKEG LMKLPFTIPE LVQSSPCRSS 120

DGIIYTGKKE DAWFVVDPAS GQRQTTLSTA AWGEGLCPGA PLLYIGRSQY VITMYDTKSR 180

ELHWNATFLD YSAAAPIQDQ GEEDAIAHLA SSGEGLLVTV SRAKGEVLWM RDFGSPVVGV 240

FAWHQETLRR APLLNMAPES LRFLLLRSQH LRLLHWDYRP AKEPNAKAQL MPTLYVGKSP 300

LGFYALKSLV HEGVALVPQG VTLARSEGPT TSDVTLRESG EREITPSTGV KYPKGSVIAA 360

QHSQWLLIGH HELPPVVHTT MLRAFPEPLR RNPETVMPRS SLFDELLEKP PNAGVPYRGP 420

LTMETETVKI HPEPGNWEPV AAGLVAVFWG AGLFFFMLWQ QANTGSPLGP RSRVLSLETP 480

AQVGLVLLQG QERSTIISQP FNPSSLSPFP TDANPEDIVV GKISFSPKEV LGRGAGGTFV 540

FRGRFEGRPV AVKRLLPSCI SLVDREVQLL RESDEHPNVV RYFCTEADQQ FRYIAIELCS 600

ATLQEYVETP DFPRRGLNLK TVLYQTMSGL AHLHSLSIVH RDLKPCNILV SSPDGHGRIR 660

AVISDFGLCK KLQGGRQSFS LRSGVPGTEG WIAPELLRED PTENPTCAVD LFSAGCVFYY 720

VVSGGRHPFG QSFRRQANIL SGTYSLEWLQ QETHDNVVGR DLIEAMIDSN PHLRPSAAQV 780

LLHPFFWNPE KQLQFFQDVS DRIEKEPAEG PIVSALEAGD HEVVRGDWRS HISLPLQTAT 840

DLRKFRTYKG SSVRDLLRAM RNKKHHYHEL PAEVQEALGH VPQGFVCYFT SRFPRLLLHT 900

HRALRLCAGE GPLRRYYAP 919

Nucleotide Sequence
(FASTA)

CCTGCTCGTT GTTCCTCTGA GTTCCAGTGT TTGGCCTCAC TTCTCTCCTG CCTCCCTTCC 60

CCAAATCTCC TTCAGTCTCT GGCCGGGAGC CCCACCGTTG TGGCCCCCGA CTCGCTGGTC 120

TTCGTCTCCA CGCTGGACGG GAGCCTCCAC GCCGTGAGCA AGACGACGGG GGATGTCGCT 180

TGGACCCTGA AGGACGACCC AGCTCTGCAG GCTCCGATCG ACGCTGGAGC CCAGCCAGCC 240

TTCCTTCCGG ACCCAAATGA CGGCAGCCTC TACGTTGTGG GGGGCAAGAA CAAGGAGGGC 300

CTGATGAAGC TGCCTTTCAC CATCCCAGAG CTGGTCCAGT CCTCTCCCTG CCGGAGCTCC 360

GATGGCATCA TCTACACAGG GAAGAAGGAA GACGCCTGGT TCGTAGTGGA TCCCGCCTCA 420

GGGCAGAGAC AGACCACGCT GTCGACAGCG GCCTGGGGGG AAGGCCTGTG CCCCGGAGCC 480

CCACTCCTCT ACATCGGCCG CTCCCAGTAC GTCATCACCA TGTACGACAC CAAGTCCCGT 540

GAACTGCACT GGAATGCCAC TTTCCTGGAC TATTCGGCTG CGGCACCAAT CCAGGACCAG 600

GGCGAGGAGG ATGCCATTGC TCACCTGGCC TCCAGCGGGG AGGGTCTGCT GGTGACGGTG 660

TCCCGGGCCA AGGGTGAGGT GCTCTGGATG CGGGACTTCG GGTCCCCTGT GGTGGGGGTC 720

TTTGCCTGGC ACCAGGAGAC CCTGCGCAGG GCCCCGCTTC TCAACATGGC CCCCGAGAGC 780

CTGCGCTTCC TCCTCCTGCG CTCCCAGCAC CTCCGCCTCC TCCACTGGGA CTACCGCCCC 840

GCCAAGGAGC CCAACGCCAA GGCCCAGCTG ATGCCAACGC TTTATGTGGG CAAATCCCCG 900

CTGGGCTTCT ACGCCTTGAA GTCTCTGGTC CATGAAGGAG TGGCGCTGGT GCCCCAGGGG 960

GTCACTCTGG CCAGGTCGGA GGGTCCCACC ACCAGTGACG TGACATTGCG GGAGTCCGGC 1020

GAGCGTGAGA TCACCCCCAG CACCGGCGTC AAGTACCCAA AGGGCAGCGT CATCGCCGCC 1080

CAACACAGCC AGTGGCTCCT CATCGGGCAC CACGAGCTCC CACCGGTGGT CCATACTACG 1140

ATGCTGAGGG CCTTTCCGGA GCCCCTGCGG AGGAACCCGG AGACCGTCAT GCCTCGCAGC 1200

TCCCTTTTTG ACGAACTTCT GGAGAAGCCC CCCAACGCAG GCGTCCCATA CCGTGGGCCT 1260

CTCACCATGG AGACGGAGAC GGTCAAAATT CACCCAGAGC CTGGCAACTG GGAGCCGGTG 1320

GCAGCAGGCC TGGTGGCCGT GTTTTGGGGC GCGGGGCTCT TCTTCTTCAT GCTCTGGCAG 1380

CAAGCGAACA CAGGGTCCCC TCTTGGACCC CGTTCCAGAG TCCTCTCCTT GGAAACACCT 1440

GCTCAGGTGG GTTTGGTCCT CTTGCAAGGA CAAGAAAGAT CCACCATAAT TAGTCAGCCT 1500

TTTAATCCTT CCTCTCTGTC TCCCTTCCCA ACAGATGCCA ACCCAGAAGA CATTGTGGTG 1560

GGGAAGATCT CCTTCAGCCC CAAGGAAGTG CTGGGCCGAG GGGCTGGGGG CACCTTTGTC 1620

TTCAGGGGCC GCTTTGAGGG CCGTCCGGTG GCCGTGAAGC GCCTGCTGCC TTCCTGCATC 1680

TCACTGGTGG ACCGTGAGGT GCAGCTGCTC CGGGAGTCCG ACGAGCACCC CAACGTCGTG 1740

CGCTACTTCT GCACCGAGGC TGACCAGCAG TTCCGCTACA TCGCCATCGA GCTCTGCTCT 1800

GCCACTTTGC AAGAGTATGT GGAGACCCCG GACTTCCCAC GGCGAGGCCT GAATCTGAAA 1860

ACGGTGCTTT ACCAAACCAT GTCCGGCTTG GCCCACCTCC ATTCCCTTAG CATCGTCCAC 1920

CGCGACCTGA AGCCCTGCAA CATCCTGGTC TCATCCCCCG ACGGCCACGG CCGGATCCGG 1980

GCGGTCATCT CCGACTTTGG CCTCTGCAAG AAGCTCCAAG GGGGCCGCCA GAGCTTCAGC 2040

CTCCGGTCGG GGGTCCCGGG CACCGAGGGA TGGATTGCAC CAGAGCTGCT GAGGGAGGAC 2100

CCCACGGAGA ACCCCACCTG TGCAGTGGAC CTCTTCTCGG CTGGCTGCGT CTTCTACTAC 2160

GTGGTGTCCG GCGGGCGGCA TCCCTTTGGG CAGAGCTTCC GTCGCCAGGC CAACATCCTA 2220

TCCGGGACCT ATAGTCTGGA GTGGCTGCAG CAGGAGACCC ATGACAACGT GGTTGGACGG 2280

GATCTGATAG AAGCCATGAT TGACAGCAAC CCCCATTTGC GCCCCTCGGC CGCCCAGGTC 2340

CTCCTGCACC CCTTTTTCTG GAACCCCGAA AAGCAGCTGC AGTTCTTCCA GGACGTCAGC 2400

GACCGCATTG AGAAGGAGCC TGCGGAGGGA CCCATTGTCA GCGCATTGGA AGCCGGGGAC 2460

CACGAAGTGG TGCGTGGCGA CTGGCGGTCC CACATCTCCC TCCCGCTGCA GACAGCCACA 2520

GACCTCCGCA AGTTCCGGAC GTACAAGGGC AGCTCCGTGC GTGACCTCCT CCGGGCCATG 2580

AGGAACAAGA AGCATCACTA CCACGAATTG CCTGCCGAGG TGCAAGAGGC CCTGGGCCAC 2640

GTCCCGCAGG GGTTTGTCTG CTATTTCACA AGCCGCTTCC CTCGGCTGCT GCTGCACACG 2700

CACCGGGCCT TGCGCCTCTG CGCCGGAGAA GGGCCCTTGC GGAGGTATTA CGCCCCA 2757

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         fspk+vlG+Ga+Gt+vfrG fegr+vavkrll+ +++l++rev+llresdehpnv+ryfc

Q: 525   FSPKEVLGRGAGGTFVFRGRFEGRPVAVKRLLPSCISLVDREVQLLRESDEHPNVVRYFC  584

         799*********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdl  120

         te d+qfryia+elc+a+lq+yve +d+  + +l+++++l q++sGlahlhsl+ivhrdl

Q: 585   TEADQQFRYIAIELCSATLQEYVETPDFP-RRGLNLKTVLYQTMSGLAHLHSLSIVHRDL  643

         *****************************.99****************************

S: 121   kpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltke  180

         kp nil+s pd++g++r++isdfGlckkl+ G++sfs rsgv+GteGwiapell+e+++e

Q: 644   KPCNILVSSPDGHGRIRAVISDFGLCKKLQGGRQSFSLRSGVPGTEGWIAPELLREDPTE  703

         ************************************************************

S: 181   rltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedli  240

         ++t avd+fs+Gcvfyyv+s+G+hpfG+s++rqanilsg++sl+ l++e++++v+ +dli

Q: 704   NPTCAVDLFSAGCVFYYVVSGGRHPFGQSFRRQANILSGTYSLEWLQQETHDNVVGRDLI  763

         ************************************************************

S: 241   skmidkdplkrpsakkvlkhplf  263

         ++mid +p  rpsa +vl hp+f

Q: 764   EAMIDSNPHLRPSAAQVLLHPFF  786

         **********************9

Domain Sequence
(FASTA)

FSPKEVLGRG AGGTFVFRGR FEGRPVAVKR LLPSCISLVD REVQLLRESD EHPNVVRYFC 60

TEADQQFRYI AIELCSATLQ EYVETPDFPR RGLNLKTVLY QTMSGLAHLH SLSIVHRDLK 120

PCNILVSSPD GHGRIRAVIS DFGLCKKLQG GRQSFSLRSG VPGTEGWIAP ELLREDPTEN 180

PTCAVDLFSA GCVFYYVVSG GRHPFGQSFR RQANILSGTY SLEWLQQETH DNVVGRDLIE 240

AMIDSNPHLR PSAAQVLLHP FF 262

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 4.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013