EKS-ANC-00143

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00143

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	518.4	4.7E-156	90	383	294

Status

Unreviewed

Ensembl Protein

ENSACAP00000012184

UniProt Accession

G1KMA1;

Protein Name

Protein Synonyms/Alias

Gene Name

STK38L

Gene Synonyms/Alias

STK38L;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000012343	ENSACAP00000012184	ENSACAT00000012432

Organism

Anolis carolinensis

Functional Description

Protein Length

464

Protein Sequence
(FASTA)

MAMTAGTPTS APMSNHTRER VTVAKLTLEN FYSNLILQHE ERETRQKKLE AAMEEEGLAD 60

EEKKLRRSQH ARKETEFLRL KRTRLGLDDF ESLKVIGRGA FGEVRLVQKK DTGHIYAMKI 120

LRKADMLEKE QVAHIRAERD ILVEADGAWV VKMFYSFQDK RNLYLIMEFL PGGDMMTLLM 180

KKDTLSEEET QFYISETVLA IDAIHQLGFI HRDIKPDNLL LDAKGHVKLS DFGLCTGLKK 240

AHRTEFYRNL THNPPSDFSF QNMNSKRKAE TWKKNRRQLA YSTVGTPDYI APEVFLQTGY 300

NKLCDWWSLG VIMYEMLIGY PPFCSETPQE TYRKVMNWKE TLVFPPEVPI SEKAKDLILK 360

FCTDAENRIG SNAVEEIKSH PFFECVDWGH IRERPAAITI EIKSIDDTSN FDEFPESDIL 420

QPVPNTTEPD YKSKDWVFLN YTYKRFEGLT QRGSIPSYMK AGKL 464

Nucleotide Sequence
(FASTA)

ATGGCAATGA CTGCTGGGAC TCCAACATCC GCTCCCATGA GCAACCACAC CCGGGAGAGA 60

GTGACTGTGG CCAAGCTCAC TCTGGAGAAC TTTTATAGTA ACTTAATTTT GCAACATGAG 120

GAAAGAGAAA CCAGGCAGAA GAAACTAGAA GCTGCCATGG AAGAAGAAGG TTTAGCAGAT 180

GAAGAGAAAA AACTACGAAG ATCTCAGCAT GCACGTAAAG AAACAGAATT TTTACGACTG 240

AAGAGAACAA GGCTAGGCCT AGATGACTTT GAATCTTTGA AAGTTATTGG AAGGGGTGCA 300

TTTGGAGAGG TACGCCTCGT CCAAAAGAAA GATACGGGTC ATATTTATGC AATGAAGATA 360

CTACGAAAAG CTGATATGTT GGAGAAAGAA CAGGTGGCTC ATATACGAGC AGAAAGAGAT 420

ATCCTGGTTG AAGCAGATGG TGCCTGGGTG GTGAAAATGT TCTATAGTTT TCAGGACAAA 480

CGTAACCTTT ATCTGATAAT GGAATTCCTT CCTGGAGGTG ATATGATGAC TTTACTAATG 540

AAGAAGGACA CCTTGTCAGA GGAAGAAACT CAGTTTTATA TATCTGAAAC AGTACTGGCC 600

ATTGATGCCA TTCATCAGCT AGGTTTTATT CACAGAGATA TTAAACCGGA TAACCTACTG 660

CTGGATGCAA AGGGCCATGT AAAACTCTCT GATTTTGGAC TATGCACAGG TTTAAAGAAA 720

GCTCACCGAA CTGAATTCTA CAGAAACCTT ACACACAATC CACCAAGTGA CTTTTCATTC 780

CAGAATATGA ATTCAAAGAG AAAAGCAGAA ACCTGGAAAA AGAATAGGCG TCAGCTGGCT 840

TATTCTACTG TTGGGACTCC AGATTATATT GCCCCAGAAG TCTTTCTGCA AACCGGTTAC 900

AACAAATTAT GTGACTGGTG GTCGTTGGGG GTGATTATGT ATGAAATGCT AATAGGGTAT 960

CCCCCTTTTT GCTCTGAAAC GCCACAGGAA ACATATCGGA AAGTTATGAA TTGGAAAGAG 1020

ACACTGGTGT TTCCACCCGA GGTTCCCATT TCAGAAAAAG CCAAGGACTT GATTCTAAAA 1080

TTTTGCACTG ATGCAGAAAA CAGAATTGGT AGCAATGCAG TAGAAGAAAT CAAATCGCAC 1140

CCGTTTTTTG AATGTGTTGA CTGGGGACAT ATCAGAGAGA GGCCGGCTGC AATCACTATC 1200

GAAATCAAGA GCATTGATGA CACTTCCAAT TTTGATGAAT TCCCAGAATC TGATATTTTA 1260

CAGCCAGTGC CAAACACCAC AGAACCTGAC TACAAATCCA AAGATTGGGT TTTTCTTAAC 1320

TACACCTACA AGAGGTTTGA AGGGCTCACT CAGCGTGGCT CCATCCCATC TTATATGAAA 1380

GCCGGGAAGT TGTGA 1395

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt+++ya+kilrk+d+l+k+qvah++aerdil+ead +w

Q: 90    FESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAW  149

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk+nlyl+me+lPGGd+mtll+kk++l+ee+++fyi+e+vla++++h+lGf

Q: 150   VVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLSEEETQFYISETVLAIDAIHQLGF  209

         ************************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+dakGh+kl+dfGlctGlkk+hr+e+y++l+++ ++d+++++  ++ +

Q: 210   IHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKA  269

         *************************************************65555555555

S: 181   rkkkknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPflaetpq  240

            kknrr+lays+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++etpq

Q: 270   ETWKKNRRQLAYSTVGTPDYIAPEVFLQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQ  329

         555*********************************************************

S: 241   etykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         ety+kv+nwketl fp+ev++se+akdli ++++dae+r+g++ v+eik+hpff

Q: 330   ETYRKVMNWKETLVFPPEVPISEKAKDLILKFCTDAENRIGSNAVEEIKSHPFF  383

         *****************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHIYAMK ILRKADMLEK EQVAHIRAER DILVEADGAW 60

VVKMFYSFQD KRNLYLIMEF LPGGDMMTLL MKKDTLSEEE TQFYISETVL AIDAIHQLGF 120

IHRDIKPDNL LLDAKGHVKL SDFGLCTGLK KAHRTEFYRN LTHNPPSDFS FQNMNSKRKA 180

ETWKKNRRQL AYSTVGTPDY IAPEVFLQTG YNKLCDWWSL GVIMYEMLIG YPPFCSETPQ 240

ETYRKVMNWK ETLVFPPEVP ISEKAKDLIL KFCTDAENRI GSNAVEEIKS HPFF 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0015629	; C:actin cytoskeleton
GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005886	; C:plasma membrane
GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007243	; P:intracellular protein kinase cascade
GO:0051128	; P:regulation of cellular component organization

KEGG

acs:100564453

;

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013