EPS-ANC-00031

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ANC-00031

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	228.8	8.4E-68	94	343	250

Status

Unreviewed

Ensembl Protein

ENSACAP00000012667

UniProt Accession

G1KMY3;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1K

Gene Synonyms/Alias

PPM1K;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000012908	ENSACAP00000012667	ENSACAT00000012923

Organism

Anolis carolinensis

Functional Description

Protein Length

371

Protein Sequence
(FASTA)

MSTAALINLV RTGGHQARRA LLTSRILQDD KCLAVVCQSS TSERRTSRFD LDGSGRPATW 60

DSFGIWDNRI DEPILLPPSI KYGKPIPKIS LSNVGCASHI GKRKENEDRF DYAQLTDDLL 120

YFAVYDGHGG VAVADFCNKY MQKYIREFLA EEKNMELVLM RAFLEIDKAY QRHAELSANA 180

TLLTAGTTAT VALLRDGIEL VVASVGDSRA LLCRKGKAMK LTIDHTPERK DEKERIKKCG 240

GFVAWNSLGQ PHVNGRLAMT RSIGDLDLKN YGVIAEPETK RIQLHHASDS FLVLTTDGIN 300

FMVNSQEICD FVNQCHDPSE AAHVVTEQAI QYGTEDNSTA IVVPFGAWGK YKNSEVSFSF 360

SRSFASSGRW A 371

Nucleotide Sequence
(FASTA)

ATGTCCACTG CTGCTTTAAT AAATCTGGTT AGAACCGGAG GCCACCAAGC GAGGAGAGCA 60

CTGCTAACGT CCCGTATTTT GCAAGACGAC AAATGCCTGG CTGTTGTGTG CCAGAGTTCG 120

ACAAGTGAAC GCAGAACCTC CCGTTTTGAC CTGGATGGTA GCGGCCGTCC TGCCACTTGG 180

GACTCATTTG GTATCTGGGA CAACCGCATT GATGAGCCCA TCCTTCTACC GCCAAGCATA 240

AAATATGGAA AGCCGATCCC GAAGATCAGC TTGTCAAATG TGGGCTGTGC CAGCCATATT 300

GGGAAAAGAA AAGAAAATGA AGACCGCTTT GATTATGCTC AGCTGACTGA TGATCTCCTG 360

TACTTTGCAG TTTATGATGG GCATGGTGGG GTGGCGGTAG CTGACTTCTG CAATAAGTAC 420

ATGCAAAAAT ATATTAGAGA ATTTCTTGCT GAGGAGAAGA ATATGGAATT AGTATTGATG 480

AGAGCTTTTT TAGAAATAGA CAAAGCATAT CAGAGACATG CTGAACTGTC TGCCAATGCT 540

ACCTTGCTGA CTGCTGGGAC CACAGCAACT GTGGCTCTGT TGCGCGATGG GATCGAGCTA 600

GTTGTGGCTA GTGTTGGCGA TAGCCGTGCA CTTTTATGTC GCAAGGGGAA AGCCATGAAG 660

TTGACCATTG ATCATACACC TGAAAGGAAG GATGAGAAAG AAAGAATCAA GAAATGTGGT 720

GGTTTTGTAG CCTGGAACAG CTTGGGACAG CCTCATGTGA ATGGCAGGCT GGCAATGACC 780

CGCAGCATAG GAGACTTGGA TCTTAAGAAC TATGGTGTGA TAGCAGAGCC AGAGACGAAA 840

CGGATTCAGT TGCACCATGC GAGTGACAGC TTCTTGGTCC TTACAACAGA CGGTATCAAC 900

TTCATGGTGA ACAGCCAAGA GATCTGTGAC TTTGTTAACC AGTGTCATGA TCCCTCTGAA 960

GCAGCTCATG TAGTAACTGA ACAGGCCATA CAGTATGGGA CAGAAGATAA CAGTACTGCT 1020

ATTGTTGTTC CATTTGGAGC GTGGGGCAAA TACAAAAATT CTGAGGTCAG CTTCTCATTT 1080

AGCCGGAGCT TTGCCTCAAG TGGACGATGG GCATGA 1116

Domain Profile

S: 3     vgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheila  62

         vg++s  g+r+e ed++++    ++ ++    l +f+vyDGhgg  va+fc + +++++

Q: 94    VGCASHIGKRKENEDRFDY----AQLTD---DLLYFAVYDGHGGVAVADFCNKYMQKYIR  146

         7999999999999999975....44333...378**************************

S: 63    eelesseseerkvkkalakaFlstdeelkvleeksldidk....sGstavvalikds.kl  117

         e l     ee++++ +l +aFl++d+++  + +++l+ ++     G+ta+val++d  +l

Q: 147   EFLA----EEKNMELVLMRAFLEIDKAY--QRHAELSANAtlltAGTTATVALLRDGiEL  200

         **98....9*******************..33333344445788*************9**

S: 118   yvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkd.ga.RvlGvLavs  175

         +va vGdSra+Lcr+gka++l+ dH+p+r+dE+eRi++ gg v+ ++ g+ +v+G La++

Q: 201   VVASVGDSRALLCRKGKAMKLTIDHTPERKDEKERIKKCGGFVAWNSlGQpHVNGRLAMT  260

         *******************************************98889999*********

S: 176   RalGdlylkpy.vtpePevtshrltsede.fliLasDGlwdvvsneeavslvrdvlekke  233

         R++Gdl+lk y v++ePe+  ++l++  + fl+L +DG+  +v+++e++++v+++++

Q: 261   RSIGDLDLKNYgVIAEPETKRIQLHHASDsFLVLTTDGINFMVNSQEICDFVNQCHD---  317

         *********999************877777***************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          ++eaa+ ++++a+++g++dn +aivv

Q: 318   -PSEAAHVVTEQAIQYGTEDNSTAIVV  343

         .************************97

Domain Sequence
(FASTA)

VGCASHIGKR KENEDRFDYA QLTDDLLYFA VYDGHGGVAV ADFCNKYMQK YIREFLAEEK 60

NMELVLMRAF LEIDKAYQRH AELSANATLL TAGTTATVAL LRDGIELVVA SVGDSRALLC 120

RKGKAMKLTI DHTPERKDEK ERIKKCGGFV AWNSLGQPHV NGRLAMTRSI GDLDLKNYGV 180

IAEPETKRIQ LHHASDSFLV LTTDGINFMV NSQEICDFVN QCHDPSEAAH VVTEQAIQYG 240

TEDNSTAIVV 250

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005739	; C:mitochondrion
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

acs:100562753

;

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013