EKS-ANC-00148

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00148

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSK	366.8	6.6E-110	69	330	262

Status

Unreviewed

Ensembl Protein

ENSACAP00000012793

UniProt Accession

H9GJI7;

Protein Name

Protein Synonyms/Alias

Gene Name

RPS6KB1

Gene Synonyms/Alias

RPS6KB1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000012931	ENSACAP00000012793	ENSACAT00000013049

Organism

Anolis carolinensis

Functional Description

Protein Length

503

Protein Sequence
(FASTA)

EAMAGVFDID LDQPDEAASD EELEEGGHLS ESMDHGGVGP YDLMEHCEKF EISETSVNRG 60

PEKIRPECFE LLRVLGKGGY GKVFQVRKVT GANTSKIFAM KVLKKAMIVR NAKDTAHTKA 120

ERNILEEVKH PFIVDLIYAF QTGGKLYLIL EYLSGGELFM QLEREGIFME DTACFYLAEI 180

SMALGHLHQK GIIYRDLKPE NIMLNHQGHV KLTDFGLCKE SIHDGTVTHT FCGTIEYMAP 240

EILMRSGHNR AVDWWSLGAL MYDMLTGAPP FTGENRKKTI DKILKCKLNL PPYLTQEARD 300

LLKKLLKRNA ASRLGAGPGD AGEVQGHPFF RHINWEELLA RKVEPPFKPL LQSEEDVSQF 360

DAKFTRQTPV DSPDDSALSE SANQVFLGFT YVAPSVLESV KEKFSFEPKI RSPRRFIGSP 420

RTPVSPVKFC PGDFWGRGSS SGMTNAQAPV EYPMESSGIE HMDVTVCGEA SAPLPIRQTN 480

TGPYKKQAFP MISKRPEHLR MNL 503

Nucleotide Sequence
(FASTA)

GAGGCCATGG CGGGCGTCTT CGACATCGAC CTGGACCAGC CCGACGAGGC CGCGTCGGAC 60

GAGGAACTGG AGGAAGGGGG TCACTTAAGC GAAAGCATGG ACCATGGTGG AGTTGGCCCA 120

TATGACCTCA TGGAGCATTG TGAAAAATTT GAGATTTCAG AAACGAGTGT GAATAGAGGT 180

CCTGAAAAGA TACGCCCAGA ATGCTTTGAA TTGCTGCGTG TTCTTGGAAA AGGTGGCTAT 240

GGAAAGGTAT TTCAAGTTCG GAAAGTGACA GGAGCAAACA CCAGTAAGAT TTTTGCCATG 300

AAGGTGCTTA AAAAGGCAAT GATTGTTAGA AATGCGAAAG ACACAGCACA CACGAAAGCC 360

GAGCGGAACA TCTTGGAGGA AGTCAAGCAT CCGTTCATTG TCGACTTGAT TTATGCCTTT 420

CAGACGGGTG GAAAACTCTA CCTCATTCTT GAGTATCTCA GTGGAGGAGA ACTGTTTATG 480

CAGTTGGAGA GAGAGGGGAT ATTTATGGAA GACACAGCTT GCTTCTACTT GGCTGAAATC 540

TCAATGGCTT TGGGGCATCT GCACCAGAAG GGGATCATTT ATCGAGATCT CAAGCCGGAA 600

AACATCATGC TGAATCATCA AGGTCATGTT AAGCTTACGG ATTTTGGACT ATGTAAGGAA 660

TCCATTCACG ACGGAACCGT CACGCACACG TTCTGTGGAA CAATAGAATA CATGGCCCCG 720

GAGATCCTGA TGAGGAGCGG GCACAACCGG GCCGTGGACT GGTGGAGTTT GGGAGCGTTA 780

ATGTACGACA TGCTGACTGG AGCACCTCCG TTCACTGGGG AGAACCGAAA GAAAACGATT 840

GACAAGATTC TCAAATGTAA ACTCAACTTG CCTCCCTACC TCACACAAGA AGCCAGAGAT 900

CTCCTGAAAA AGCTGCTAAA GAGAAATGCT GCCTCACGCC TAGGAGCTGG TCCTGGAGAT 960

GCTGGAGAAG TTCAGGGTCA TCCTTTCTTC AGACACATTA ACTGGGAAGA GCTGCTGGCC 1020

CGGAAGGTGG AGCCTCCCTT TAAACCATTA TTGCAATCCG AAGAGGACGT GAGCCAGTTT 1080

GATGCAAAAT TTACTCGCCA GACTCCTGTT GATAGCCCTG ATGACTCAGC CCTCAGTGAA 1140

AGTGCCAACC AGGTCTTCCT GGGCTTTACG TATGTGGCTC CCTCCGTACT TGAAAGCGTG 1200

AAAGAGAAGT TTTCCTTTGA ACCAAAAATC CGATCACCTC GCAGATTCAT TGGCAGCCCG 1260

CGGACGCCCG TCAGCCCTGT TAAGTTCTGT CCCGGGGATT TCTGGGGACG AGGCAGTTCC 1320

TCCGGCATGA CCAATGCGCA GGCACCCGTG GAGTACCCCA TGGAGAGCAG CGGGATCGAG 1380

CACATGGACG TGACGGTGTG CGGAGAGGCC TCGGCGCCGC TCCCCATCCG GCAAACCAAC 1440

ACCGGCCCGT ACAAAAAACA GGCCTTCCCC ATGATCTCCA AGAGGCCGGA GCATTTGCGC 1500

ATGAACCTAT GA 1512

Domain Profile

S: 1     fellkvlgkGaygkvflvrkvekkdtgklyavKvlkkaelvk..kkkertkeereiLeev  58

         fell+vlgkG+ygkvf+vrkv++ +t+k++a+Kvlkka +v+  k++++tk+er+iLeev

Q: 69    FELLRVLGKGGYGKVFQVRKVTGANTSKIFAMKVLKKAMIVRnaKDTAHTKAERNILEEV  128

         89***********************************9999999****************

S: 59    ehpfivklheafqdekklylvlellkGgeLlerlkkkklfseeeasfilaelvlaleylH  118

         +hpfiv+l +afq+  klyl+le+l+GgeL+++l+++++f+e++a+f+lae+++al +lH

Q: 129   KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLH  188

         ************************************************************

S: 119   skgvvyrDLkpeNilldeeghvkltDfglakekiaeneekaysfcgTleyvaPevlkrkg  178

         +kg++yrDLkpeNi+l+++ghvkltDfgl+ke+i ++++ +++fcgT+ey+aPe+l+r+g

Q: 189   QKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESI-HDGTVTHTFCGTIEYMAPEILMRSG  247

         *********************************9.9999999******************

S: 179   ydeavDlwslGvllyemLtGktPftgeerketlarilkgkfslklpaweelseeakdlvk  238

         +++avD+wslG+l+y+mLtG++Pftge+rk+t+++ilk+k  l+lp +  l++ea+dl+k

Q: 248   HNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCK--LNLPPY--LTQEARDLLK  303

         ****************************************..9*****..**********

S: 239   klLkkdpakRlga...taeeikehkfl  262

         klLk++ a+Rlga   +a e++ h+f+

Q: 304   KLLKRNAASRLGAgpgDAGEVQGHPFF  330

         *************9999********97

Domain Sequence
(FASTA)

FELLRVLGKG GYGKVFQVRK VTGANTSKIF AMKVLKKAMI VRNAKDTAHT KAERNILEEV 60

KHPFIVDLIY AFQTGGKLYL ILEYLSGGEL FMQLEREGIF MEDTACFYLA EISMALGHLH 120

QKGIIYRDLK PENIMLNHQG HVKLTDFGLC KESIHDGTVT HTFCGTIEYM APEILMRSGH 180

NRAVDWWSLG ALMYDMLTGA PPFTGENRKK TIDKILKCKL NLPPYLTQEA RDLLKKLLKR 240

NAASRLGAGP GDAGEVQGHP FF 262

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007165	; P:signal transduction

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR016238	; Ribosomal_S6_kinase.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013