EKS-ANC-00282

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00282

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/BUB	338.9	1.6E-101	789	1055	267

Status

Unreviewed

Ensembl Protein

ENSACAP00000012897

UniProt Accession

H9GJN0;

Protein Name

Protein Synonyms/Alias

Gene Name

BUB1

Gene Synonyms/Alias

BUB1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000013107	ENSACAP00000012897	ENSACAT00000013155
ENSACAG00000013107	ENSACAP00000012894	ENSACAT00000013152

Organism

Anolis carolinensis

Functional Description

Protein Length

1088

Protein Sequence
(FASTA)

VSCPETLCRM FEAYIQNYKG DDPLDPWYRY FQWVEGLSEA EGKQNYLPRL LEQLVRTFFN 60

EKRYYDDTRF INCCVKFANI MNEPCQFFDY IYSQGIGSKS SALYIAWAEQ LAMQGTVSLA 120

SSVIQKGIQN GAQPAEKLQQ QYRLLQSHLT HGQIPSHVGA LQPLDPQLSG QMPSKADPNY 180

QKQVVGYMEK QSKELPVVVK MADAAERYQP RYVTTISKSE VLPTPSSGPP LEQKAMYAKD 240

LLYCEGSELC FEEVRAKAHF KRAERLKRQK EWEDEEKEFM KKKENELLEL QKLQQKLEQL 300

SQTSSQQMAP VPSVHQSSRS TTVDKNGLST QNSAGQYYPS LAAPSSGRYS ENSLNFVLHP 360

HENPQHRSIL AAASASPAKH SPANSCCISH PRFILKSISF SSFFVAKLDA SAYTQSAYTY 420

LNNSHQKLQH SMEPHKVEDS SNRQATPNTS NLTLSKVQPS PTVHTKEALA LQGFIMNVFH 480

APSVRDTTMF SEEDEEFEDY CRNKDIFPFI FSKFFLGPCE VPNVNKSTVP VVPDPPAFTI 540

FEDENAEVPQ PCPKSTEVRV LGERPIADCA AKQAEVIQPP EGMTGDFTVW AGHCNKTLAP 600

SPNSSKDFAR AAHLASTPFS GISGHTDKVT QRKDQERLEK WQVVSGVREL AVCKDVTQRT 660

PGCFTILWEA PLISPHKYLQ TTQIGTGGEA IFASDLGGGG CMLLDISWSL AEQRHGSSAE 720

LPVCHYMNTS FSDAKNEVIE NPWDDSLTRQ LLSALPKPIN AYSNTFEWGS NVPVLRPKTN 780

VCLGSMPCHV DYLLGEGAFA QVYQASVPDM DNTKNNCKVI LKVQKPASPW EFYIATQLTE 840

RLKPSLRHLF IHFYSGHFFR NGSILVGELY SFGTLLNTIN IYRKLMEKVM PQALVVYFTV 900

KILHMVEELH KCGIIHGDIK PDNFIFGERF FDTDTCDIDG TSHGLSIIDF GQSIDMTLFP 960

DGTVFTGKCE TSGFQCIEMM THKPWTYQTD YFGIAATVYC MLFGTYMKVR NEQGIWKPEG 1020

VFRRVPNADV WTDLFFTLLN IQDCSHLPRL GDLRAKLRDL FLTLYANKII ALRNRLAVLL 1080

VENKRLRK 1088

Nucleotide Sequence
(FASTA)

GTAAGCTGTC CCGAGACCCT TTGTAGGATG TTTGAAGCTT ATATACAGAA CTACAAAGGC 60

GATGACCCAC TTGATCCTTG GTATAGGTAC TTTCAGTGGG TCGAAGGACT CTCAGAGGCA 120

GAAGGAAAAC AAAACTACCT GCCACGTTTA CTGGAGCAGC TTGTGAGAAC GTTTTTTAAT 180

GAGAAGAGAT ACTACGATGA CACTAGATTC ATCAACTGCT GTGTGAAATT TGCTAACATT 240

ATGAATGAGC CATGTCAGTT TTTTGACTAT ATTTATAGCC AAGGAATTGG CAGTAAGTCC 300

TCTGCTTTAT ACATTGCTTG GGCCGAGCAA CTCGCCATGC AAGGAACTGT GTCTCTTGCA 360

AGCAGTGTTA TTCAGAAGGG GATTCAGAAT GGAGCACAGC CAGCTGAAAA ACTGCAGCAG 420

CAATATAGGC TTTTGCAGAG TCACTTGACG CATGGCCAAA TTCCAAGCCA CGTTGGTGCC 480

TTGCAGCCGC TTGACCCTCA GCTGTCCGGT CAGATGCCTT CTAAAGCTGA TCCAAACTAC 540

CAGAAACAGG TTGTGGGGTA TATGGAGAAA CAAAGCAAGG AACTTCCGGT AGTGGTGAAG 600

ATGGCGGACG CTGCAGAACG CTATCAACCT AGATATGTAA CCACTATTTC AAAATCAGAA 660

GTCTTACCAA CACCATCATC CGGCCCCCCG CTTGAACAGA AGGCCATGTA TGCGAAGGAC 720

CTTCTGTATT GTGAAGGCTC TGAACTGTGC TTTGAAGAAG TGAGAGCCAA AGCACATTTC 780

AAAAGGGCAG AACGCCTGAA AAGGCAGAAG GAATGGGAAG ATGAAGAGAA AGAGTTTATG 840

AAAAAGAAAG AAAATGAACT CCTTGAGCTG CAGAAGTTAC AGCAGAAATT GGAGCAGCTC 900

TCCCAGACAT CATCCCAGCA AATGGCGCCA GTGCCATCTG TTCACCAGTC TTCTCGAAGC 960

ACTACAGTGG ATAAAAATGG CCTGTCTACA CAAAACAGCG CAGGTCAGTA TTATCCAAGC 1020

TTGGCGGCAC CTTCCTCGGG AAGATATTCA GAGAATTCTT TAAATTTCGT TCTGCACCCT 1080

CATGAAAATC CCCAGCACCG ATCCATACTG GCTGCAGCAT CGGCCTCACC AGCCAAACAC 1140

AGCCCTGCAA ATAGCTGCTG CATTTCCCAT CCTAGGTTTA TACTCAAGTC AATAAGTTTT 1200

TCCAGTTTTT TTGTGGCAAA ATTAGATGCC TCGGCTTATA CTCAGTCGGC TTATACGTAC 1260

TTGAACAACT CTCATCAGAA GCTGCAGCAT TCCATGGAAC CGCACAAGGT GGAGGATTCT 1320

TCTAATCGTC AGGCCACTCC AAACACATCA AACCTGACAC TGTCTAAAGT ACAGCCATCT 1380

CCAACTGTTC ATACAAAAGA AGCTCTGGCC TTGCAAGGTT TCATCATGAA TGTGTTCCAT 1440

GCACCTTCCG TAAGAGACAC CACTATGTTT TCAGAAGAGG ACGAGGAATT TGAGGACTAC 1500

TGTAGGAATA AAGATATATT TCCCTTCATC TTTTCAAAAT TCTTTTTAGG ACCATGTGAG 1560

GTTCCAAATG TTAATAAGTC TACTGTGCCT GTTGTTCCTG ATCCACCTGC TTTCACCATA 1620

TTTGAAGATG AGAATGCAGA AGTCCCACAA CCATGTCCAA AGTCAACAGA AGTCAGAGTT 1680

TTGGGTGAAC GTCCCATAGC AGACTGTGCA GCCAAACAAG CAGAGGTTAT TCAGCCACCT 1740

GAGGGCATGA CAGGTGACTT CACTGTTTGG GCGGGTCACT GCAATAAAAC CCTGGCTCCC 1800

AGTCCAAACA GCTCCAAGGA TTTTGCTCGT GCTGCTCATC TTGCCTCAAC TCCATTCAGT 1860

GGAATTTCAG GACATACAGA CAAAGTGACT CAGAGAAAAG ATCAGGAGCG ACTTGAGAAA 1920

TGGCAAGTCG TTTCTGGTGT AAGAGAATTG GCCGTCTGCA AGGATGTTAC CCAGAGGACA 1980

CCTGGATGCT TTACCATCCT GTGGGAGGCT CCTCTCATTT CCCCACATAA ATACTTACAA 2040

ACAACTCAGA TAGGAACGGG GGGTGAGGCA ATATTTGCAT CAGACCTCGG TGGAGGTGGA 2100

TGCATGCTGC TTGACATATC TTGGTCCTTG GCAGAGCAAA GACATGGTTC TTCAGCTGAG 2160

TTACCTGTGT GCCATTACAT GAATACTTCT TTTTCAGATG CTAAAAATGA AGTAATTGAA 2220

AACCCTTGGG ATGACAGCTT AACCCGCCAG CTGCTATCTG CATTGCCCAA ACCCATAAAT 2280

GCCTACTCCA ATACTTTTGA ATGGGGATCA AATGTTCCAG TTCTCAGACC GAAGACGAAC 2340

GTGTGCTTGG GTTCCATGCC CTGCCATGTT GACTATTTAC TCGGGGAAGG AGCTTTTGCC 2400

CAAGTCTATC AAGCTTCTGT TCCTGATATG GACAACACAA AAAATAATTG TAAAGTAATA 2460

CTGAAGGTGC AGAAACCTGC AAGCCCCTGG GAATTCTACA TAGCTACTCA GCTGACAGAG 2520

AGGCTGAAGC CAAGCCTGCG TCATCTGTTC ATCCACTTCT ATTCTGGTCA TTTCTTCCGT 2580

AATGGAAGTA TTTTAGTTGG GGAACTTTAC AGTTTTGGAA CTTTACTGAA CACCATAAAC 2640

ATATACAGAA AACTGATGGA GAAGGTGATG CCCCAAGCGC TTGTCGTCTA CTTCACTGTC 2700

AAAATCCTCC ACATGGTAGA AGAGCTTCAC AAATGTGGGA TAATTCATGG AGACATTAAG 2760

CCTGACAACT TTATTTTTGG TGAAAGGTTT TTTGACACCG ACACGTGTGA CATCGATGGC 2820

ACATCTCATG GCTTGTCAAT TATTGATTTT GGCCAAAGCA TAGACATGAC CCTTTTCCCA 2880

GATGGAACAG TGTTCACTGG AAAGTGTGAA ACATCTGGAT TTCAGTGTAT CGAAATGATG 2940

ACTCACAAGC CATGGACTTA CCAGACAGAC TATTTTGGCA TTGCTGCGAC AGTGTACTGC 3000

ATGCTCTTTG GCACATATAT GAAAGTGAGA AATGAACAAG GGATCTGGAA ACCTGAGGGT 3060

GTCTTCAGGA GGGTCCCCAA TGCGGATGTT TGGACTGACC TCTTCTTCAC TTTGTTGAAC 3120

ATCCAGGATT GCAGCCACTT GCCTCGCCTG GGAGACTTGC GGGCAAAACT AAGAGACTTA 3180

TTTCTGACAT TGTATGCCAA CAAAATAATC GCTTTGCGGA ATAGGCTTGC AGTGTTGCTT 3240

GTTGAAAATA AGCGTCTAAG GAAGTAA 3267

Domain Profile

S: 2     eiekeigeGayakvykaeh....dsksgelvalKvekpansWefYIclqlkeRlkeeell  57

         +++ ++geGa+a+vy+a      ++k++ +v+lKv+kpa++WefYI +ql+eRlk ++l

Q: 789   HVDYLLGEGAFAQVYQASVpdmdNTKNNCKVILKVQKPASPWEFYIATQLTERLK-PSLR  847

         68999************999888889999**************************.77**

S: 58    ksiieissallfqdasllvleyasygtlldlinkvkevtnkvmdeelvvllivqllkive  117

         + +i+++s + f+++s+lv e++s+gtll+ in +++  +kvm+++lvv+++v++l++ve

Q: 848   HLFIHFYSGHFFRNGSILVGELYSFGTLLNTINIYRKLMEKVMPQALVVYFTVKILHMVE  907

         ************************************************************

S: 118   klHeveIiHgDlkPdnfllgnrimdkad..kdkeekglkliDfgrsiDmkllpdgtkfkg  175

         +lH+++IiHgD+kPdnf+ g+r+ d      d  ++gl +iDfg+siDm+l+pdgt f+g

Q: 908   ELHKCGIIHGDIKPDNFIFGERFFDTDTcdIDGTSHGLSIIDFGQSIDMTLFPDGTVFTG  967

         ***********************98876114566788***********************

S: 176   kaktdafeciemlagkswsYqvDlfglaavihvllfgkyleviqeggswklkqkikrllk  235

         k++t++f+ciem++ k+w+Yq+D+fg+aa+++++lfg+y++v +e+g wk++  ++r ++

Q: 968   KCETSGFQCIEMMTHKPWTYQTDYFGIAATVYCMLFGTYMKVRNEQGIWKPEGVFRRVPN  1027

         ************************************************************

S: 236   kelwekiferlLNisdastlpsleelve  263

          ++w+++f +lLNi+d+s+lp l+ l++

Q: 1028  ADVWTDLFFTLLNIQDCSHLPRLGDLRA  1055

         *************************996

Domain Sequence
(FASTA)

HVDYLLGEGA FAQVYQASVP DMDNTKNNCK VILKVQKPAS PWEFYIATQL TERLKPSLRH 60

LFIHFYSGHF FRNGSILVGE LYSFGTLLNT INIYRKLMEK VMPQALVVYF TVKILHMVEE 120

LHKCGIIHGD IKPDNFIFGE RFFDTDTCDI DGTSHGLSII DFGQSIDMTL FPDGTVFTGK 180

CETSGFQCIE MMTHKPWTYQ TDYFGIAATV YCMLFGTYMK VRNEQGIWKP EGVFRRVPNA 240

DVWTDLFFTL LNIQDCSHLP RLGDLRA 267

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR013212	; Mad3_BUB1_I.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR015661	; Ser/Thr_kinase_Bub1.

Pfam

PF08311	; Mad3_BUB1_I; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00777

; Mad3_BUB1_I; 1.

Prosites

PS51489	; BUB1_N; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013