EKS-ANC-00033

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00033

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/VRK	405.9	6.2E-122	36	302	267

Status

Unreviewed

Ensembl Protein

ENSACAP00000013437

UniProt Accession

G1KP35;

Protein Name

Protein Synonyms/Alias

Gene Name

VRK1

Gene Synonyms/Alias

VRK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000013622	ENSACAP00000013437	ENSACAT00000013711

Organism

Anolis carolinensis

Functional Description

Protein Length

394

Protein Sequence
(FASTA)

MPNVKKTARK RGPPKRKLAE EFPPGEIFTD LLKKEWKLGP VIGKGGFGCL YLADVNSSKP 60

VTSDAPYVIK VEPSDNGPLF TELSFYMRAA KPDLIKKWIS SHKLKYLGVP KYWGSGLHQK 120

NNKSYRFMVM DRFGKDLQKI FEERGNQFTR KTVLQLGLRI LDVLEYVHEH EYVHADIKAS 180

NLLLGYKAPH QVYLVDYGLA FRYCPEGNHR DYKENPKRCH DGTLEFTSID AHKGVAPSRR 240

GDLEILGYCM ICWLSGKLPW QDNLEDPNYV RDSKIRYTDT IKELMSECFP GKNKPDELTR 300

YMEKVMTLAY NEKPPYEELR EIFLQGLKII GEKDDGILDM EVSENGDVPA KPALKREREE 360

SESTSTSVCE RKKCSDLQSR IIVRITSKRE RSQK 394

Nucleotide Sequence
(FASTA)

ATGCCTAATG TAAAGAAGAC TGCTAGAAAA AGAGGTCCTC CAAAGCGGAA ACTTGCAGAA 60

GAATTCCCGC CAGGAGAAAT TTTTACTGAT CTTTTAAAGA AAGAGTGGAA ACTTGGCCCA 120

GTTATAGGCA AAGGTGGCTT TGGCTGCCTG TATCTTGCTG ATGTTAATTC TTCAAAACCA 180

GTTACCAGTG ATGCACCCTA TGTTATAAAA GTGGAACCTA GTGACAATGG ACCCCTCTTT 240

ACAGAATTAA GTTTCTACAT GCGAGCTGCT AAACCAGATC TAATTAAGAA ATGGATTTCT 300

TCTCATAAAC TGAAATACTT GGGGGTACCA AAGTACTGGG GTTCTGGCTT GCATCAAAAG 360

AATAACAAAA GTTATAGATT TATGGTGATG GACAGATTTG GGAAAGATCT TCAGAAGATC 420

TTTGAAGAGC GAGGAAATCA GTTTACACGC AAAACAGTAT TACAGTTGGG GTTGAGAATA 480

CTGGATGTGT TGGAATATGT TCATGAACAT GAATATGTAC ATGCAGACAT CAAGGCCTCA 540

AATCTTCTCC TGGGCTATAA AGCTCCACAT CAGGTGTACT TGGTGGATTA TGGTCTTGCA 600

TTTCGGTATT GTCCAGAAGG CAATCACAGA GATTACAAAG AAAATCCCAA ACGCTGTCAT 660

GATGGAACAC TTGAATTTAC CAGTATTGAT GCACACAAAG GAGTGGCTCC TTCAAGACGG 720

GGGGACCTGG AAATTCTGGG TTATTGTATG ATCTGTTGGC TTAGTGGCAA GCTACCTTGG 780

CAAGACAACC TGGAAGATCC CAATTATGTC AGAGACTCAA AAATTAGGTA TACAGATACT 840

ATCAAAGAAC TAATGTCTGA GTGTTTTCCC GGAAAAAATA AACCAGATGA GCTAACGAGG 900

TATATGGAAA AAGTGATGAC TTTGGCCTAT AATGAAAAAC CACCTTATGA GGAATTACGA 960

GAAATATTTC TTCAAGGTCT CAAAATCATT GGTGAGAAGG ATGATGGCAT ATTGGACATG 1020

GAGGTTTCAG AAAATGGAGA TGTTCCAGCA AAGCCTGCAC TTAAGCGTGA GAGAGAGGAA 1080

AGTGAATCTA CATCTACAAG TGTGTGTGAG AGAAAGAAGT GCTCTGATTT ACAATCCAGG 1140

ATTATTGTGA GAATAACATC AAAAAGGGAA AGGTCCCAAA AG 1182

Domain Profile

S: 1     wklgkkigkggfGeiyla..ltckkeekdaklvvkvepkenGpLfvelkfyqraakkeqi  58

         wklg  igkggfG++yla  +++k + +da +v+kvep++nGpLf+el fy+raak++ i

Q: 36    WKLGPVIGKGGFGCLYLAdvNSSKPVTSDAPYVIKVEPSDNGPLFTELSFYMRAAKPDLI  95

         9*****************9999999***********************************

S: 59    kkwkkkkklkllgiPtliasGlhefegekyRflvlprlgrdLqklleqngkrlsektvlq  118

         kkw+  +klk+lg+P++++sGlh++++++yRf+v++r+g+dLqk+ e+ g+++++ktvlq

Q: 96    KKWISSHKLKYLGVPKYWGSGLHQKNNKSYRFMVMDRFGKDLQKIFEERGNQFTRKTVLQ  155

         ************************************************************

S: 119   lavrlldvleylHeneYvHgdikAanllleeeeasqvyLvdyGlayrycpegkhkeyked  178

         l++r+ldvley+He+eYvH+dikA+nlll+++ + qvyLvdyGla+rycpeg+h++yke+

Q: 156   LGLRILDVLEYVHEHEYVHADIKASNLLLGYKAPHQVYLVDYGLAFRYCPEGNHRDYKEN  215

         ************************************************************

S: 179   krraHdGtleftslDaHkGvapsrRsDleiLgYcllkWltgkLPWeallkdpekvqkake  238

         ++r+HdGtlefts+DaHkGvapsrR+DleiLgYc++ Wl+gkLPW+++l+dp++v+++k

Q: 216   PKRCHDGTLEFTSIDAHKGVAPSRRGDLEILGYCMICWLSGKLPWQDNLEDPNYVRDSKI  275

         ************************************************************

S: 239   kfldelpellkkllkkkssseelakyl  265

         ++ d ++el++++++ k+++ el++y+

Q: 276   RYTDTIKELMSECFPGKNKPDELTRYM  302

         *************************97

Domain Sequence
(FASTA)

WKLGPVIGKG GFGCLYLADV NSSKPVTSDA PYVIKVEPSD NGPLFTELSF YMRAAKPDLI 60

KKWISSHKLK YLGVPKYWGS GLHQKNNKSY RFMVMDRFGK DLQKIFEERG NQFTRKTVLQ 120

LGLRILDVLE YVHEHEYVHA DIKASNLLLG YKAPHQVYLV DYGLAFRYCP EGNHRDYKEN 180

PKRCHDGTLE FTSIDAHKGV APSRRGDLEI LGYCMICWLS GKLPWQDNLE DPNYVRDSKI 240

RYTDTIKELM SECFPGKNKP DELTRYM 267

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005795	; C:Golgi stack
GO:0005730	; C:nucleolus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0090166	; P:Golgi disassembly
GO:0046777	; P:protein autophosphorylation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013