EKS-ANC-00248

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00248

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	256.0	3.1E-76	48	308	261

Status

Unreviewed

Ensembl Protein

ENSACAP00000013770

UniProt Accession

H9GKK5;

Protein Name

Protein Synonyms/Alias

Gene Name

STK11

Gene Synonyms/Alias

STK11;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000013986	ENSACAP00000013770	ENSACAT00000014051

Organism

Anolis carolinensis

Functional Description

Protein Length

379

Protein Sequence
(FASTA)

MDLEPQQLGM FVESELMSVG MDTFIHRIDS TEVIYQPRRK RAKLIGKYLM GDLLGEGSYG 60

KVKEMLDSET LCRRAVKILK KKKLRRIPNG EANVKKEIQL LRRLRHKNVI QLVDVLYNEE 120

KQKMYMVMEY CVCGMQEMLD SVPEKKFPVF QAHGYFCQLI DGLEYLHSQG IVHKDIKPGN 180

LLLTTNGTLK ISDLGVAEAL HPFAEDDVCR TSQGSPAFQP PEIANGLDTF SGFKVDIWSA 240

GVTLYNITTG LYPFEGDNIY KLFENIGKGD YTIPEDCGPP LSDLLRGMLE YDPSKRFSIQ 300

QIRHHNWFRK KHTQSEALVP IPPSPETKDR WRSMTVVPYL EDLHGYNEEE DDDEGLKEDY 360

LEDEIIYTQD FTVPGKEIA 379

Nucleotide Sequence
(FASTA)

ATGGATCTGG AGCCCCAGCA GTTGGGCATG TTTGTCGAAA GCGAATTGAT GTCGGTAGGC 60

ATGGACACGT TCATCCATCG CATCGACTCC ACGGAAGTGA TCTACCAACC CCGGCGGAAG 120

AGAGCCAAGC TCATTGGCAA ATACCTGATG GGGGATTTGC TCGGAGAAGG GTCTTATGGC 180

AAAGTCAAGG AGATGCTGGA CTCCGAAACC CTCTGCAGGA GAGCGGTCAA GATCCTGAAG 240

AAGAAGAAAC TGCGCCGGAT CCCCAACGGC GAAGCCAATG TGAAAAAGGA AATACAGCTC 300

CTGCGTCGGT TACGGCACAA AAACGTAATC CAGTTGGTCG ACGTGTTGTA CAACGAGGAG 360

AAACAGAAGA TGTATATGGT GATGGAGTAC TGTGTGTGCG GCATGCAGGA GATGTTGGAC 420

AGCGTCCCTG AAAAGAAGTT TCCGGTCTTT CAAGCACACG GGTATTTTTG CCAGCTGATC 480

GATGGCTTGG AGTATCTGCA CAGCCAGGGC ATCGTTCACA AAGACATCAA ACCAGGGAAC 540

CTCTTGCTCA CAACCAACGG GACGCTGAAG ATTTCAGACC TGGGAGTGGC AGAGGCTTTG 600

CACCCGTTTG CTGAGGACGA CGTGTGCCGG ACGAGCCAGG GCTCCCCTGC TTTTCAGCCT 660

CCGGAAATCG CCAACGGCCT CGACACCTTT TCGGGCTTCA AAGTGGATAT TTGGTCCGCG 720

GGCGTCACAC TGTACAACAT AACAACCGGC CTTTATCCCT TTGAGGGCGA TAATATTTAT 780

AAGCTGTTTG AAAACATTGG GAAAGGGGAC TACACGATCC CGGAAGACTG TGGCCCTCCG 840

CTCTCGGACC TGCTTAGAGG AATGCTTGAA TACGATCCAT CCAAGAGGTT TTCAATACAA 900

CAGATCAGGC ACCACAACTG GTTCCGGAAG AAACACACGC AGTCGGAGGC CCTGGTGCCC 960

ATCCCGCCCA GCCCGGAGAC CAAGGACCGG TGGCGGAGCA TGACGGTGGT GCCTTACCTG 1020

GAAGACCTGC ACGGCTACAA CGAGGAGGAG GACGACGACG AGGGCCTGAA GGAGGACTAT 1080

CTGGAGGACG AGATCATCTA CACTCAGGAC TTCACCGTTC CAGGTAAGGA GATAGCC 1137

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl..seeslekikrEieilkklkhp  58

         y +++ lGegs+gkVk++ ++et  + avKi+kkkkl    +   ++k+Ei++l++l+h+

Q: 48    YLMGDLLGEGSYGKVKEMLDSETLCRRAVKILKKKKLrrIPNGEANVKKEIQLLRRLRHK  107

         778999******************************965334567***************

S: 59    niikllevi..etkkklylvleyasgg..eLfdyieekgrlkekearklfkqlvsavkYl  114

         n+i+l++v+  e+k+k+y+v+ey+  g  e++d +  +++++  +a+ +f ql+++++Yl

Q: 108   NVIQLVDVLynEEKQKMYMVMEYCVCGmqEMLDSV-PEKKFPVFQAHGYFCQLIDGLEYL  166

         ********9888999********998888*****7.7889********************

S: 115   hskgivHrDlKpeNllldkkenikiaDFGlan...lfkegklletfcGsppYaaPellkg  171

         hs+givH+D+Kp Nlll++++++ki+D+G+a+    f e+++++t++Gsp++++Pe+ +g

Q: 167   HSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEalhPFAEDDVCRTSQGSPAFQPPEIANG  226

         *******************************966567788******************99

S: 172   .kkYegpkvDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlr  230

          ++++g kvD+Ws+Gv+Ly++ tg +Pf+++n+ +l+e+i kg+++ip+ + + l++Llr

Q: 227   lDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGDYTIPEDCGPPLSDLLR  286

         899*********************************************************

S: 231   klLvvdpekRatieeilkhewl  252

          +L+ dp+kR++i++i++h+w+

Q: 287   GMLEYDPSKRFSIQQIRHHNWF  308

         *********************7

Domain Sequence
(FASTA)

YLMGDLLGEG SYGKVKEMLD SETLCRRAVK ILKKKKLRRI PNGEANVKKE IQLLRRLRHK 60

NVIQLVDVLY NEEKQKMYMV MEYCVCGMQE MLDSVPEKKF PVFQAHGYFC QLIDGLEYLH 120

SQGIVHKDIK PGNLLLTTNG TLKISDLGVA EALHPFAEDD VCRTSQGSPA FQPPEIANGL 180

DTFSGFKVDI WSAGVTLYNI TTGLYPFEGD NIYKLFENIG KGDYTIPEDC GPPLSDLLRG 240

MLEYDPSKRF SIQQIRHHNW F 261

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013