EKS-ANC-00052

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00052

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	380.9	3.1E-114	141	424	284

Status

Unreviewed

Ensembl Protein

ENSACAP00000014183

UniProt Accession

H9GL36;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK18

Gene Synonyms/Alias

CDK18;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000014284	ENSACAP00000014183	ENSACAT00000014474

Organism

Anolis carolinensis

Functional Description

Protein Length

473

Protein Sequence
(FASTA)

MNKMKTFKRR FSLSVPRTET IEESLAEFTE QFNQLNNRKN EDMAQGHLNL GHLNKDIKTQ 60

PSSFSPVEGQ SQMEVQYRNG NQRRFSMEDV SRRLSLSVDI RLPPEFLQKL ERESPEMSKP 120

LSRMSRRASL SDIGFGKMET YVKLEKLGEG TYATVFKGRS KLTKNLVALK EIRLEHEEGA 180

PCTAIREVSL LKNLKHANIV TLHDIIHTKC SLTLVFEYLD SDLKQYLDNC GNLMSMHNVK 240

SKIFMFQLLR GLSYCHQLKI LHRDLKPQNL LINGKGELKL ADFGLARAKS VPTKTYSNEV 300

VTLWYRPPDV LLGSTEYSTP IDMWGVGCIH YEMVTGRPMF PGSTVKEELH LIFRILGTPT 360

EETWPGITSN EEFKTYNFTH HRAQPLINHV PRLDTEGIDL LSSLLLYEAK QRISAEAALR 420

HPYFMALGEH VHLLPETASI FSLKEIQLQK DPGYRGSNFQ HSARGKNRRQ SIF 473

Nucleotide Sequence
(FASTA)

ATGAACAAAA TGAAAACTTT CAAGCGTCGT TTTTCTCTTT CGGTTCCCCG GACAGAGACG 60

ATTGAGGAAT CACTAGCAGA GTTTACAGAG CAGTTCAACC AGCTCAACAA CAGAAAGAAT 120

GAAGATATGG CACAAGGACA TCTGAACCTG GGTCATCTGA ACAAGGATAT CAAGACACAG 180

CCCAGCTCTT TTTCACCTGT GGAAGGCCAG TCCCAAATGG AAGTGCAGTA CCGAAATGGC 240

AACCAACGGC GGTTTTCTAT GGAGGATGTC AGCAGGCGCC TCTCTCTCTC CGTGGATATT 300

CGCCTTCCCC CAGAGTTCCT CCAGAAACTA GAGAGGGAAA GTCCAGAGAT GTCTAAGCCT 360

CTAAGCAGAA TGTCTCGGCG GGCATCACTT TCAGACATCG GGTTTGGGAA GATGGAGACT 420

TATGTTAAGC TTGAGAAGCT GGGGGAGGGC ACCTATGCCA CTGTCTTTAA AGGGCGCAGT 480

AAGCTCACCA AGAACCTGGT TGCTCTAAAA GAAATCCGGC TGGAACATGA AGAAGGAGCC 540

CCTTGCACAG CTATCCGAGA GGTTTCCTTA CTGAAGAATC TGAAGCATGC AAATATTGTG 600

ACCCTCCATG ATATCATCCA CACAAAATGC TCCCTCACGC TGGTCTTTGA ATATCTGGAC 660

AGTGACCTGA AGCAGTATCT GGATAACTGT GGAAATCTGA TGAGCATGCA TAATGTGAAG 720

TCCAAGATCT TCATGTTTCA GCTACTGCGT GGGTTGTCCT ATTGCCACCA GCTTAAGATC 780

CTACATAGGG ATCTGAAGCC ACAAAATCTG CTTATTAATG GAAAGGGAGA ACTGAAGCTC 840

GCTGACTTTG GTCTAGCCAG AGCCAAGTCT GTCCCTACAA AAACGTATTC CAATGAAGTG 900

GTCACATTGT GGTATCGGCC TCCTGATGTT CTTCTAGGAT CTACAGAGTA CTCCACTCCC 960

ATTGACATGT GGGGTGTGGG TTGCATACAC TATGAAATGG TTACAGGACG TCCCATGTTT 1020

CCAGGATCTA CAGTGAAAGA GGAATTACAT TTAATATTCA GGATATTGGG CACCCCTACA 1080

GAAGAAACCT GGCCTGGCAT TACATCTAAT GAGGAATTCA AGACATATAA TTTTACACAT 1140

CATCGAGCCC AGCCATTGAT AAATCACGTG CCAAGACTAG ATACAGAAGG GATCGACCTG 1200

TTGTCAAGTC TCCTCCTGTA TGAAGCCAAA CAACGCATTT CGGCTGAGGC AGCCTTGAGG 1260

CACCCGTACT TCATGGCCCT GGGCGAACAC GTGCACCTCC TTCCTGAGAC TGCCTCCATC 1320

TTTTCTCTGA AGGAAATACA GCTTCAAAAG GACCCAGGTT ACAGAGGTTC AAACTTCCAG 1380

CACTCAGCTC GAGGAAAGAA CAGGAGGCAA AGCATATTTT AA 1422

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y klek+geGty++v+k+++k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 141   YVKLEKLGEGTYATVFKGRSKLTKNLVALKEIRLEHE-EGAPCTAIREVSLLKNLKHANI  199

         789*********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevk..slllqlleglaylHs  118

         v+L+++++ +k +l+Lvfe+l++dLk++l+++ +  +s+++vk   +++qll+gl+y+H+

Q: 200   VTLHDIIH-TKCSLTLVFEYLDSDLKQYLDNCGN-LMSMHNVKskIFMFQLLRGLSYCHQ  257

         ********.99*********************99.666665541179*************

S: 119   nkilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeY  178

          kilHRDlKpqNlLi+ +g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg++eY

Q: 258   LKILHRDLKPQNLLINGKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEY  317

         ************************************************************

S: 179   stavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ks  237

         st +D+W+vgci  e++t +p+f+g++ +++l+ if++lgtp+e++wp++++ +e+k ++

Q: 318   STPIDMWGVGCIHYEMVTGRPMFPGSTVKEELHLIFRILGTPTEETWPGITSNEEFKtYN  377

         *********************************************************889

S: 238   fpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         f++++++ l ++v++l+++++dll++ll ++ k+Risa++al+h+yf

Q: 378   FTHHRAQPLINHVPRLDTEGIDLLSSLLLYEAKQRISAEAALRHPYF  424

         **********************************************9

Domain Sequence
(FASTA)

YVKLEKLGEG TYATVFKGRS KLTKNLVALK EIRLEHEEGA PCTAIREVSL LKNLKHANIV 60

TLHDIIHTKC SLTLVFEYLD SDLKQYLDNC GNLMSMHNVK SKIFMFQLLR GLSYCHQLKI 120

LHRDLKPQNL LINGKGELKL ADFGLARAKS VPTKTYSNEV VTLWYRPPDV LLGSTEYSTP 180

IDMWGVGCIH YEMVTGRPMF PGSTVKEELH LIFRILGTPT EETWPGITSN EEFKTYNFTH 240

HRAQPLINHV PRLDTEGIDL LSSLLLYEAK QRISAEAALR HPYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013