EKS-ANC-00236

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00236

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	333.4	7.0E-100	30	280	251

Status

Unreviewed

Ensembl Protein

ENSACAP00000014276

UniProt Accession

G1KPZ9;

Protein Name

Protein Synonyms/Alias

Gene Name

NUAK2

Gene Synonyms/Alias

NUAK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000014491	ENSACAP00000014276	ENSACAT00000014569

Organism

Anolis carolinensis

Functional Description

Protein Length

631

Protein Sequence
(FASTA)

ASAAALPQPP AAKRQAVKRH YHKHNLRRHY EFLETLGKGT YGKVKKARER SGKLVAIKSI 60

RKDKIKDEQD LIHIRREIEI MSSLNHPHII AVHEVFENNS KIVIVMEYAS KGDLYDYIAE 120

RQRLTEQEAR HFFRQVVSAV YYCHKNGIVH RDLKLENILL DANGNIKIAD FGLSNVFQQD 180

RLLQTFCGSP LYASPEIVNG RPYKGPEVDS WSLGVLLYIL IHGAMPFDGH DYKTLVKQIT 240

SGDYREPTKL SDACGLIRWM LMVNPERRAT IEDIASHWWV NWGYKVPVGE QESSRDHESS 300

LATVAEWLRR SSRPLFENGS KVRCFFKQHI PGVTLERQRS LKKSKKENDI SHALQETGPP 360

PENPSKSILK RPKGILKKRN SCEKTQVSPP PATAGSVDSW KEENTGSTMD LACVLSSRAL 420

ACKAEGIVAT PPMPKKGILK KPQKRESGYY SSPERSESTE VLDSKNLDLD ANAFADNNTS 480

APTLGNAHAS RKGILKHNGK FSSSSTESEG VPAKVFSTFV EVNLPKMSMA SRSRPSSAVS 540

EDSILSSESF DQLDLPDRLQ ADGGAPMRAA ISADDLLQLE ETEGEMGSRR LRRWTVTQCQ 600

NPLVDSCFSL ADCENVTEVY KRAVALSMKL S 631

Nucleotide Sequence
(FASTA)

GCCTCTGCCG CCGCCCTCCC GCAGCCCCCC GCGGCCAAGA GGCAAGCGGT GAAGCGGCAC 60

TACCACAAGC ACAACCTCCG GCGCCACTAC GAGTTCCTCG AGACGCTGGG CAAAGGCACC 120

TACGGGAAGG TGAAGAAGGC GAGGGAGCGC TCCGGGAAAC TGGTTGCTAT CAAGTCTATT 180

CGGAAAGATA AAATAAAGGA TGAGCAGGAT CTTATCCATA TCCGGAGAGA AATAGAAATA 240

ATGTCCTCCC TCAATCATCC CCACATCATT GCTGTCCATG AAGTATTTGA AAACAACAGC 300

AAGATTGTCA TTGTGATGGA ATATGCCAGC AAGGGGGATC TCTACGATTA CATTGCCGAG 360

CGCCAGAGAC TAACTGAGCA AGAAGCCCGG CACTTCTTCC GGCAGGTGGT GTCTGCTGTC 420

TACTACTGTC ACAAGAATGG AATTGTTCAC AGAGATCTAA AGCTTGAGAA CATCCTGCTG 480

GATGCAAATG GCAACATCAA GATCGCAGAC TTTGGCCTCT CGAATGTTTT CCAGCAGGAC 540

CGACTCCTGC AGACTTTCTG TGGCAGCCCT CTCTATGCAT CTCCTGAGAT AGTCAATGGA 600

AGGCCTTACA AAGGACCTGA GGTTGATAGC TGGTCCCTTG GTGTGCTCCT TTATATTTTG 660

ATTCATGGTG CGATGCCTTT TGATGGTCAT GATTACAAGA CTCTAGTCAA GCAGATTACA 720

AGTGGGGACT ACAGAGAGCC CACCAAACTT TCAGATGCCT GTGGCCTGAT ACGGTGGATG 780

CTAATGGTGA ACCCAGAGCG CCGAGCCACC ATTGAAGATA TTGCTAGCCA CTGGTGGGTG 840

AACTGGGGCT ACAAGGTGCC CGTTGGGGAA CAGGAGTCCT CACGTGACCA TGAATCTTCA 900

TTAGCCACCG TAGCAGAATG GCTGCGCCGG TCTTCGAGGC CTCTCTTTGA AAATGGCTCC 960

AAGGTTCGCT GCTTCTTCAA GCAACATATT CCCGGTGTCA CGCTAGAGAG ACAACGCTCC 1020

CTTAAGAAGT CAAAGAAGGA GAATGACATA TCTCATGCTC TGCAAGAGAC TGGTCCTCCT 1080

CCAGAGAACC CATCCAAATC TATCCTGAAG AGGCCCAAAG GCATCTTGAA GAAGAGAAAT 1140

TCCTGTGAGA AGACCCAAGT TTCTCCTCCT CCAGCAACTG CAGGTTCTGT TGACTCTTGG 1200

AAAGAGGAGA ATACAGGATC TACTATGGAC CTGGCTTGTG TCTTATCATC CAGGGCTTTA 1260

GCCTGCAAGG CAGAAGGCAT TGTAGCCACT CCTCCCATGC CCAAGAAGGG AATCTTGAAG 1320

AAGCCTCAGA AGAGAGAATC TGGTTATTAT TCTTCCCCAG AGCGTAGTGA ATCCACAGAG 1380

GTTTTAGACT CTAAAAACCT GGATCTCGAT GCCAATGCCT TTGCTGACAA TAATACATCT 1440

GCTCCAACCT TGGGAAATGC TCATGCCAGT CGGAAAGGCA TCCTGAAGCA CAATGGCAAA 1500

TTCTCCTCCA GCAGCACCGA GTCAGAAGGT GTGCCTGCCA AGGTCTTTTC TACTTTTGTA 1560

GAGGTCAACT TGCCCAAAAT GTCTATGGCC TCCCGTAGTC GTCCATCCAG TGCTGTGAGT 1620

GAGGATAGTA TTCTTTCATC AGAATCGTTT GATCAGCTGG ACTTGCCTGA TCGATTACAG 1680

GCAGATGGAG GAGCACCCAT GCGTGCAGCC ATCTCTGCAG ATGACCTGCT TCAGCTGGAA 1740

GAGACAGAGG GGGAGATGGG GTCTCGCCGA CTCCGCCGTT GGACAGTTAC CCAGTGCCAA 1800

AACCCCTTGG TGGATAGCTG CTTCTCTTTG GCGGACTGTG AAAATGTCAC CGAAGTCTAT 1860

AAACGGGCTG TGGCTTTAAG CATGAAACTG AGCTGA 1896

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y++l+tlG+g++gkVk+a+++  ++ va+K i+k+k+ +e+ l +i+rEiei+++l+hp+

Q: 30    YEFLETLGKGTYGKVKKARER-SGKLVAIKSIRKDKIkDEQDLIHIRREIEIMSSLNHPH  88

         99****************987.799**********996677788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         ii ++ev+e+++k+++v+eyas+g+L+dyi e++rl+e+ear++f+q+vsav Y+h++gi

Q: 89    IIAVHEVFENNSKIVIVMEYASKGDLYDYIAERQRLTEQEARHFFRQVVSAVYYCHKNGI  148

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlK+eN+lld+++nikiaDFGl+n+f++++ll+tfcGsp Ya+Pe+++g++Y+gp+v

Q: 149   VHRDLKLENILLDANGNIKIADFGLSNVFQQDRLLQTFCGSPLYASPEIVNGRPYKGPEV  208

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D WslGv+Ly+l+ g++Pfd++++k+l+++i++g+++ p+kls+ +  L+r +L+v+pe+

Q: 209   DSWSLGVLLYILIHGAMPFDGHDYKTLVKQITSGDYREPTKLSDAC-GLIRWMLMVNPER  267

         *****************************************99876.7************

S: 240   Ratieeilkhewl  252

         Ratie+i +h w+

Q: 268   RATIEDIASHWWV  280

         ************6

Domain Sequence
(FASTA)

YEFLETLGKG TYGKVKKARE RSGKLVAIKS IRKDKIKDEQ DLIHIRREIE IMSSLNHPHI 60

IAVHEVFENN SKIVIVMEYA SKGDLYDYIA ERQRLTEQEA RHFFRQVVSA VYYCHKNGIV 120

HRDLKLENIL LDANGNIKIA DFGLSNVFQQ DRLLQTFCGS PLYASPEIVN GRPYKGPEVD 180

SWSLGVLLYI LIHGAMPFDG HDYKTLVKQI TSGDYREPTK LSDACGLIRW MLMVNPERRA 240

TIEDIASHWW V 251

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0030036	; P:actin cytoskeleton organization
GO:0042149	; P:cellular response to glucose starvation
GO:0043066	; P:negative regulation of apoptotic process

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013