EKS-ANC-00268

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00268

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	448.2	1.1E-134	235	522	288

Status

Unreviewed

Ensembl Protein

ENSACAP00000014455

UniProt Accession

H9GLF0;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1A

Gene Synonyms/Alias

BMPR1A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000014543	ENSACAP00000014455	ENSACAT00000014750

Organism

Anolis carolinensis

Functional Description

Protein Length

533

Protein Sequence
(FASTA)

MICLKVYVRL LGFFAFIIFQ VQGQNLDSML HGTGMKTDPD QKKQEDGVTL APEDTLPFLQ 60

CYCSGHCPED AVNNTCKTNG HCFAIIEEEE NGDIIMASGC MKYEGSDFQC KDSPRAQLRR 120

TIECCRTDFC NQDLQPTLPP PSSPDGFFDG SIHWRAVLIS MGVCIISLIV LFCCYSFMHY 180

CKWAAKRQCY NRDLEQDEAF IPVGESLKDL IDQSQSSGSG SGLPLLVQRT IAKQIQMVRQ 240

VGKGRYGEVW MGKWRGEKVA VKVFFTTEEA SWFRETEIYQ TVLMRHENIL GFIAADIKGT 300

GSWTHLYLIT DYHENGSLYD YLKCTTLDTR SLLKLAYSAA CGLCHLHTEI YGTQGKPAIA 360

HRDLKSKNVL IKRNGTCCIA DLGLAVKFNS DTNEVDVPLN TRVGTKRYMA PEVLDETLNK 420

NHFQSYIMAD IYSFGLIIWE MARRCVTGGI VEDYQLPYYD MVPNDPSYED MREVVCVKHL 480

RPVVSNRWNS DECLRAILKL MCECWAHNPA SRLTALRIKK TLGKMVESQD VKI 533

Nucleotide Sequence
(FASTA)

ATGATTTGTC TGAAAGTTTA CGTCAGATTG CTGGGGTTCT TTGCATTCAT CATTTTTCAA 60

GTTCAAGGAC AGAATTTGGA CAGCATGTTG CATGGGACAG GGATGAAAAC AGATCCTGAT 120

CAAAAGAAGC AGGAAGATGG TGTAACCCTG GCTCCAGAGG ACACCTTGCC TTTTTTACAG 180

TGCTACTGTT CAGGGCACTG TCCAGAAGAT GCAGTTAATA ACACATGCAA AACAAATGGG 240

CATTGCTTTG CCATCATTGA AGAAGAGGAA AATGGAGACA TTATAATGGC TTCTGGCTGC 300

ATGAAGTATG AAGGTTCAGA CTTCCAGTGC AAGGACTCAC CAAGAGCACA ACTGCGGAGG 360

ACAATTGAAT GTTGTCGGAC AGATTTCTGT AATCAAGATC TGCAGCCCAC CTTGCCCCCT 420

CCTTCTTCTC CAGATGGTTT CTTTGATGGC AGTATACATT GGAGAGCTGT GCTTATTTCT 480

ATGGGAGTCT GTATAATAAG TTTGATTGTC TTATTTTGCT GCTACAGCTT CATGCATTAT 540

TGTAAATGGG CAGCAAAAAG ACAGTGTTAC AATCGTGACC TGGAACAGGA TGAAGCCTTT 600

ATTCCTGTTG GGGAGTCTCT GAAAGATCTT ATTGACCAAT CACAGAGTTC TGGTAGTGGT 660

TCAGGACTTC CACTTTTGGT CCAACGAACT ATTGCCAAAC AGATTCAGAT GGTACGACAA 720

GTTGGAAAAG GTCGATATGG TGAAGTCTGG ATGGGTAAAT GGCGAGGTGA AAAAGTGGCA 780

GTGAAAGTAT TTTTCACCAC CGAAGAAGCC AGTTGGTTTC GAGAAACTGA GATTTACCAG 840

ACAGTTCTCA TGCGTCATGA GAATATACTT GGTTTTATAG CAGCAGATAT TAAAGGCACA 900

GGCTCCTGGA CCCATCTATA TTTGATTACA GATTATCATG AAAATGGATC ATTGTATGAC 960

TACCTAAAGT GTACCACTTT GGACACCAGA TCTCTACTCA AACTGGCTTA TTCTGCTGCA 1020

TGCGGTCTCT GCCATTTACA CACAGAGATA TATGGCACAC AAGGCAAGCC TGCTATCGCC 1080

CACAGAGACC TGAAAAGTAA AAATGTCTTG ATAAAGAGGA ATGGGACTTG CTGTATTGCT 1140

GACTTGGGTC TAGCTGTCAA ATTTAACAGT GATACAAATG AAGTTGATGT CCCTTTGAAT 1200

ACAAGAGTGG GAACAAAGCG TTACATGGCA CCAGAGGTCC TAGATGAGAC TCTGAATAAA 1260

AACCATTTCC AGTCATACAT CATGGCTGAC ATCTATAGCT TTGGCTTGAT AATTTGGGAA 1320

ATGGCTCGGC GTTGTGTCAC AGGAGGAATC GTTGAAGACT ACCAACTCCC CTACTATGAT 1380

ATGGTGCCAA ATGATCCTTC ATATGAAGAT ATGAGGGAGG TGGTGTGTGT TAAGCACCTG 1440

CGCCCAGTAG TATCTAATAG ATGGAACAGT GATGAGTGCT TAAGAGCAAT ATTGAAATTA 1500

ATGTGTGAAT GCTGGGCCCA CAATCCTGCC TCCAGACTGA CTGCATTGAG GATTAAGAAG 1560

ACTCTTGGCA AGATGGTAGA ATCACAAGAT GTTAAAATTT GA 1602

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         +++++++gkGrygeVw++k+rge+vAvK+f+t++easw+rE+eiyqtvl+rhenil+fia

Q: 235   IQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIA  294

         799*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++s+t+l+l+t+yhe+gsL+dyLk +tld+++ll+la+s+a+Gl+hLH+ei gt+

Q: 295   ADIKGTGSWTHLYLITDYHENGSLYDYLKCTTLDTRSLLKLAYSAACGLCHLHTEIYGTQ  354

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  KpaiaHRDlkskN+l+k+++tcciaDlGLa+k++++++e+d+  n++vGtkRYmaPE

Q: 355   G--KPAIAHRDLKSKNVLIKRNGTCCIADLGLAVKFNSDTNEVDVPLNTRVGTKRYMAPE  412

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e+ln ++f+++ +aD+Ys+gL++WE+a+Rc + +++ve+y+lp++++v++dPs+e+m

Q: 413   VLDETLNKNHFQSYIMADIYSFGLIIWEMARRCVT-GGIVEDYQLPYYDMVPNDPSYEDM  471

         ***********************************.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         +evv++k+lrP ++++w+++e+l+++ kl+ ecW+++p++Rltalr+kk+l

Q: 472   REVVCVKHLRPVVSNRWNSDECLRAILKLMCECWAHNPASRLTALRIKKTL  522

         *************************************************97

Domain Sequence
(FASTA)

IQMVRQVGKG RYGEVWMGKW RGEKVAVKVF FTTEEASWFR ETEIYQTVLM RHENILGFIA 60

ADIKGTGSWT HLYLITDYHE NGSLYDYLKC TTLDTRSLLK LAYSAACGLC HLHTEIYGTQ 120

GKPAIAHRDL KSKNVLIKRN GTCCIADLGL AVKFNSDTNE VDVPLNTRVG TKRYMAPEVL 180

DETLNKNHFQ SYIMADIYSF GLIIWEMARR CVTGGIVEDY QLPYYDMVPN DPSYEDMREV 240

VCVKHLRPVV SNRWNSDECL RAILKLMCEC WAHNPASRLT ALRIKKTL 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013