EPS-ANC-00027

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ANC-00027

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	289.4	2.8E-86	23	293	271

Status

Unreviewed

Ensembl Protein

ENSACAP00000015250

UniProt Accession

H9GMF1;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1B

Gene Synonyms/Alias

PPM1B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000015485	ENSACAP00000015250	ENSACAT00000015559

Organism

Anolis carolinensis

Functional Description

Protein Length

477

Protein Sequence
(FASTA)

MGAFLDKPKT EKHNAHGAGN GLRYGLSSMQ GWRVEMEDAH TAVVGIPHGL EDWSFFAVYD 60

GHAGSRVANY CSNHLLEHIT SNEDFRGTEQ PSSTLEPSVE NVKSGIRTGF LKIDEYMRNF 120

SDLRNGMDRS GSTAVGVMIS PDHIYFINCG DSRAVLYRNG QVCFSTQDHK PCNPREKERI 180

QNAGGSVMIQ RVNGSLAVSR ALGDYDYKCV DGKGPTEQLV SPEPEVYEIV RAEEDEFIVL 240

ACDGIWDVMS NEELCEFVKS RLEVSDDLEK VCNWVVDTCL HKGSRDNMSI VLVCFSNAPK 300

VSDEAVKRDA ELDKHLESRV EEIMEKSGEE GMPDLAHVMR ILSAENIPNL PPGGGLAGKR 360

NIIEAVYNRL NPHRENDGDP GDAAAGGTQG KLVEALRQVR ITHRGNYRHL LEDVLISYRL 420

AKMQGEDCSH AESASASTSE STDGSSNEEK TTRAGCEPPL AEMQDANEDS EMSDEHC 477

Nucleotide Sequence
(FASTA)

ATGGGTGCAT TTTTGGATAA ACCAAAAACT GAGAAACATA ATGCCCATGG GGCAGGAAAT 60

GGGCTGCGTT ATGGCCTAAG CAGTATGCAA GGATGGAGAG TGGAAATGGA AGATGCTCAC 120

ACAGCTGTTG TAGGAATTCC TCATGGTTTG GAGGACTGGT CCTTTTTTGC TGTTTATGAT 180

GGTCATGCAG GATCTCGTGT GGCAAATTAC TGCTCAAACC ACTTATTAGA ACACATCACT 240

AGCAATGAAG ACTTCAGGGG AACAGAACAG CCCAGCTCTA CTCTCGAACC TTCAGTGGAA 300

AATGTAAAGA GTGGAATCAG AACTGGCTTT TTGAAAATTG ATGAATACAT GCGCAATTTT 360

TCAGACCTCA GAAATGGCAT GGACCGGAGT GGCTCAACAG CAGTGGGAGT TATGATTTCA 420

CCTGATCACA TTTACTTTAT CAACTGTGGA GACTCACGTG CTGTTCTGTA TAGGAATGGA 480

CAAGTCTGCT TTTCAACACA GGATCACAAG CCTTGTAATC CAAGGGAGAA GGAGAGAATC 540

CAAAATGCAG GTGGGAGTGT CATGATTCAG CGTGTTAATG GCTCATTAGC CGTTTCCCGT 600

GCTTTGGGGG ACTATGACTA CAAATGTGTG GATGGTAAAG GCCCTACAGA GCAACTTGTT 660

TCTCCAGAAC CTGAGGTTTA TGAAATTGTA AGAGCAGAAG AGGATGAATT TATTGTCCTG 720

GCTTGTGATG GAATCTGGGA TGTAATGAGC AACGAAGAGC TCTGTGAATT TGTTAAGTCT 780

AGGCTTGAAG TATCAGATGA TCTGGAAAAA GTGTGCAATT GGGTTGTGGA TACTTGTTTA 840

CACAAGGGAA GCCGTGATAA CATGAGTATT GTTCTAGTTT GCTTTTCAAA TGCTCCTAAG 900

GTCTCAGATG AGGCAGTGAA AAGAGATGCA GAATTGGATA AGCATTTGGA ATCACGGGTG 960

GAAGAAATTA TGGAGAAATC AGGCGAAGAA GGAATGCCTG ACCTTGCTCA TGTTATGCGC 1020

ATTTTGTCTG CAGAGAATAT CCCAAACCTG CCACCAGGAG GTGGTCTAGC TGGCAAGCGA 1080

AATATAATTG AAGCTGTTTA TAACAGGCTG AACCCACACA GAGAGAATGA TGGGGACCCT 1140

GGCGATGCTG CAGCAGGTGG AACGCAGGGA AAGTTGGTGG AAGCTCTCAG ACAAGTGAGA 1200

ATTACTCATA GGGGGAACTA CCGCCACCTT CTGGAGGACG TGCTGATTAG TTACAGGCTA 1260

GCTAAAATGC AGGGAGAAGA TTGCTCTCAT GCCGAATCAG CTTCAGCCTC AACCTCAGAG 1320

TCCACTGATG GATCCAGTAA CGAAGAGAAA ACCACCAGAG CAGGATGTGA GCCCCCGCTT 1380

GCTGAAATGC AGGATGCTAA TGAAGATTCA GAGATGAGTG ATGAACATTG T 1431

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++s++g+r emeda+t++ ++    + +d ++ff+vyDGh+gs+va++cs++l e++

Q: 23    RYGLSSMQGWRVEMEDAHTAVVGIPH--GLED-WSFFAVYDGHAGSRVANYCSNHLLEHI  79

         69****************98555444..4434.***************************

S: 62    aeele.........sseseerkvkkalakaFlstdeelkvleeksldidksGstavvali  112

         + + +         + e++ ++vk+ ++++Fl++de ++++++ ++ +d+sGstav ++i

Q: 80    TSNEDfrgteqpssTLEPSVENVKSGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMI  139

         ***99********9999*******************************************

S: 113   kdsklyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvL  172

         +++++y++n+GdSravL rng+++  ++dHkp +++E+eRi++aggsv+ +   Rv+G+L

Q: 140   SPDHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQ---RVNGSL  196

         ***************************************************...******

S: 173   avsRalGdlylk.........pyvtpePevtshrltsedefliLasDGlwdvvsneeavs  223

         avsRalGd+++k         ++v+pePev+++ + +edef++La+DG+wdv+snee+++

Q: 197   AVSRALGDYDYKcvdgkgpteQLVSPEPEVYEIVRAEEDEFIVLACDGIWDVMSNEELCE  256

         ************************************************************

S: 224   lvrdvlekkeaeqeaakkLvklalargskdnvsaivv  260

         +v+++le +++++++++ +v+++l++gs+dn+s+++v

Q: 257   FVKSRLEVSDDLEKVCNWVVDTCLHKGSRDNMSIVLV  293

         ********************************98875

Domain Sequence
(FASTA)

RYGLSSMQGW RVEMEDAHTA VVGIPHGLED WSFFAVYDGH AGSRVANYCS NHLLEHITSN 60

EDFRGTEQPS STLEPSVENV KSGIRTGFLK IDEYMRNFSD LRNGMDRSGS TAVGVMISPD 120

HIYFINCGDS RAVLYRNGQV CFSTQDHKPC NPREKERIQN AGGSVMIQRV NGSLAVSRAL 180

GDYDYKCVDG KGPTEQLVSP EPEVYEIVRA EEDEFIVLAC DGIWDVMSNE ELCEFVKSRL 240

EVSDDLEKVC NWVVDTCLHK GSRDNMSIVL V 271

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0000287	; F:magnesium ion binding
GO:0030145	; F:manganese ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR012911	; PP2C_C.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481	; PP2C; 1.
PF07830	; PP2C_C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013