EKS-ANC-00416

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00416

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	528.9	2.4E-159	162	419	258

Status

Unreviewed

Ensembl Protein

ENSACAP00000016283

UniProt Accession

G1KSR7;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK3

Gene Synonyms/Alias

SGK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000016487	ENSACAP00000016283	ENSACAT00000016607

Organism

Anolis carolinensis

Functional Description

Protein Length

496

Protein Sequence
(FASTA)

AQRQRTMDLK ESCPSVSIPS SDEHRVKKKR FTVYKVLVSV GTNEWFVFRR YAEFDKLYHT 60

LRKQFPTMNL RIPAKRIFGD NFDPDFIKQR RAGLNEFIQN LVQQPELCNH PDVRSFLQMD 120

NPKHQYDPSE DEDERNSQKL NSISQNINLG PSGNPHAKPT DFDFLKVIGK GSFGKVLLAK 180

RKLDGKFYAV KVLQKKIVLN RKEQKHIMAE RNVLLKNVKH PFLVGLHYSF QTTEKLYFVL 240

DFVNGGELFF HLQKERSFPE HRARFYAAEI ASALGYLHSV KIVYRDLKPE NILLDSLGHV 300

VLTDFGLCKE GMATSDTTAT FCGTPEYLAP EVIRKQPYDN TVDWWCLGAV LYEMLYGLPP 360

FYCRDVAEMY ENILHKPLHL RPGISLTAWS ILEELLEKDR QNRLGAKEDF LEIQSHPFFE 420

SLNWTDLLQK KIPPPFNPNV SGPDDIRNFD TAFTEEMVPY SVCISSDYNI VNASVLEADD 480

AFIGFSYAPP SEDLFH 496

Nucleotide Sequence
(FASTA)

GCCCAAAGAC AACGTACAAT GGATCTCAAA GAAAGCTGTC CAAGTGTTAG TATCCCAAGC 60

TCTGATGAAC ACAGGGTGAA GAAAAAAAGA TTTACTGTTT ACAAAGTTTT GGTTTCAGTT 120

GGCACCAATG AGTGGTTTGT CTTCAGGCGA TATGCTGAAT TTGATAAGTT GTATCATACG 180

CTAAGGAAAC AGTTCCCCAC TATGAATTTG AGAATTCCTG CTAAAAGAAT ATTTGGAGAT 240

AATTTTGATC CAGATTTTAT TAAGCAGAGA AGAGCAGGAC TGAATGAATT CATTCAAAAT 300

TTAGTACAAC AACCAGAACT TTGCAATCAC CCAGACGTGA GATCATTTCT TCAGATGGAC 360

AATCCAAAGC ACCAGTATGA TCCATCTGAA GATGAGGATG AAAGGAACAG TCAAAAGCTA 420

AATTCTATCT CACAAAATAT CAACCTGGGA CCATCTGGAA ATCCTCACGC TAAACCAACA 480

GACTTTGACT TTCTGAAAGT TATTGGGAAG GGCAGCTTTG GCAAGGTTCT TCTCGCAAAA 540

CGAAAACTGG ATGGAAAGTT TTATGCTGTT AAAGTACTAC AGAAAAAAAT TGTTCTAAAC 600

AGGAAAGAGC AAAAACATAT CATGGCTGAA CGTAATGTCC TGCTGAAAAA TGTGAAACAT 660

CCATTTTTAG TTGGATTGCA TTATTCATTC CAAACCACGG AGAAGCTTTA TTTTGTTCTG 720

GATTTTGTTA ATGGAGGGGA ACTCTTCTTT CATTTGCAAA AAGAACGTTC CTTTCCTGAA 780

CACAGAGCCA GGTTTTATGC TGCTGAAATA GCCAGTGCAT TGGGCTACCT ACACTCCGTT 840

AAAATTGTAT ACAGAGATTT AAAACCAGAA AACATTCTTC TAGATTCATT GGGACATGTT 900

GTCTTAACAG ATTTTGGGCT TTGTAAAGAA GGAATGGCTA CTTCGGACAC TACAGCAACA 960

TTCTGTGGAA CTCCTGAGTA CCTTGCCCCT GAGGTGATCA GAAAACAGCC CTATGATAAC 1020

ACAGTAGATT GGTGGTGCCT TGGAGCTGTT CTATATGAAA TGTTATATGG TTTGCCTCCA 1080

TTTTACTGCC GTGATGTTGC TGAAATGTAT GAAAACATTC TTCACAAACC CCTACATTTA 1140

AGGCCAGGTA TCAGTCTCAC CGCTTGGTCT ATTCTGGAAG AACTTCTGGA GAAAGACAGG 1200

CAAAACAGAC TTGGAGCTAA AGAAGATTTT CTTGAAATTC AAAGTCATCC CTTTTTTGAA 1260

TCTCTCAACT GGACTGACCT TCTGCAAAAA AAGATCCCAC CACCATTTAA CCCTAATGTG 1320

TCTGGTCCAG ATGACATCAG GAACTTTGAT ACAGCTTTTA CAGAAGAGAT GGTACCTTAT 1380

TCCGTCTGCA TTTCCTCTGA CTATAATATT GTAAACGCCA GTGTACTCGA AGCAGATGAT 1440

GCATTCATTG GATTTTCTTA CGCTCCACCT TCTGAGGACT TATTTCACTA A 1491

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkvllakrk d+kfyavkvlqkk++l++ke+khimaernvllknvkhp

Q: 162   FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHP  221

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqt+eklyfvld+vnggelffhlq+ersf+e+rarfyaaeiasalgylhs++

Q: 222   FLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQKERSFPEHRARFYAAEIASALGYLHSVK  281

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds ghvvltdfglcke+++++dtt+tfcgtpeylapev+rk+pyd+t

Q: 282   IVYRDLKPENILLDSLGHVVLTDFGLCKEGMATSDTTATFCGTPEYLAPEVIRKQPYDNT  341

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfy+rdvaemy+nil+kpl+l+pgis++a+++leellekdr+

Q: 342   VDWWCLGAVLYEMLYGLPPFYCRDVAEMYENILHKPLHLRPGISLTAWSILEELLEKDRQ  401

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlgakedflei++h+ff

Q: 402   NRLGAKEDFLEIQSHPFF  419

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVLLAKR KLDGKFYAVK VLQKKIVLNR KEQKHIMAER NVLLKNVKHP 60

FLVGLHYSFQ TTEKLYFVLD FVNGGELFFH LQKERSFPEH RARFYAAEIA SALGYLHSVK 120

IVYRDLKPEN ILLDSLGHVV LTDFGLCKEG MATSDTTATF CGTPEYLAPE VIRKQPYDNT 180

VDWWCLGAVL YEMLYGLPPF YCRDVAEMYE NILHKPLHLR PGISLTAWSI LEELLEKDRQ 240

NRLGAKEDFL EIQSHPFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016023	; C:cytoplasmic membrane-bounded vesicle
GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR001683	; Phox.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.
PF00787	; PX; 1.

SMARTs

SM00312	; PX; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013