EPS-ANC-00042

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-ANC-00042

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP5	602.1	1.6E-181	191	502	312

Status

Unreviewed

Ensembl Protein

ENSACAP00000016482

UniProt Accession

H9GNJ6;

Protein Name

Serine/threonine-protein phosphatase

Protein Synonyms/Alias

Gene Name

PPP5C

Gene Synonyms/Alias

PPP5C;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000016703	ENSACAP00000016482	ENSACAT00000016808

Organism

Anolis carolinensis

Functional Description

Protein Length

505

Protein Sequence
(FASTA)

AAMAEGERAE NGAGAGVSSG RPPQEGEPGT MERAESLKTQ ANDYFKAKDY ENAVKYYTQA 60

IELNPTNAIY YGNRSLAYLR TECYGYALAD ATKAIELDKK YIKGYYRRAT SNMALGKFKA 120

ALRDYETVVK VKPNDKDAKM KYQECNKIVK QKAFERAIAS DEHKRSVVDS LDIENMTIED 180

EYSGPKLDDG KVTPEFMKEL MQWYKDQKKL HRKCAYQILV QAKEVLSKLP TLVETTLKET 240

EKITVCGDTH GQYYDLLNIF ELNGLPAETN PYIFNGDFVD RGSFSVEVIL TLFGFKLLYP 300

DHFHLLRGNH ETDNMNQIYG FEGEVKAKYT AQMFELFSEV FEWLPLAQCI NGKVLIMHGG 360

LFSEDGVTLD DIRKIERNRQ PPDSGPMCDL LWSDPQPQNG RSISKRGVSC QFGPDVTQSF 420

LERNHLDYII RSHEVKPEGY EVAHDGKCVT VFSAPNYCDQ MGNKGSYIHL KGSDLRPEFH 480

QFTAVPHPNV KPMMYANSLL QLGMM 505

Nucleotide Sequence
(FASTA)

GCGGCGATGG CGGAGGGAGA GAGGGCGGAG AACGGTGCCG GTGCAGGAGT CAGCTCCGGG 60

CGGCCGCCTC AGGAAGGGGA GCCGGGGACG ATGGAGCGGG CCGAATCCCT CAAGACCCAG 120

GCGAACGATT ACTTCAAAGC AAAGGACTAC GAGAATGCCG TGAAGTATTA CACCCAAGCC 180

ATTGAACTGA ACCCCACTAA TGCCATCTAT TATGGCAACC GGAGCTTGGC TTACCTGCGG 240

ACAGAATGCT ACGGATACGC GCTTGCGGAC GCCACGAAGG CCATCGAGTT GGACAAGAAA 300

TATATCAAAG GCTACTACAG GAGGGCCACC AGCAACATGG CGTTGGGCAA GTTCAAGGCA 360

GCCTTGCGGG ACTACGAGAC GGTTGTGAAG GTGAAACCAA ACGACAAGGA TGCCAAGATG 420

AAGTACCAGG AGTGCAACAA GATTGTGAAA CAGAAGGCTT TTGAGCGGGC CATCGCCAGC 480

GATGAGCACA AGCGGTCCGT GGTCGACTCT CTGGACATTG AGAACATGAC CATTGAGGAT 540

GAGTACAGCG GCCCCAAGCT GGATGATGGG AAAGTGACCC CCGAATTCAT GAAGGAGTTA 600

ATGCAATGGT ACAAGGATCA AAAGAAGCTT CACAGGAAGT GTGCCTACCA GATTTTGGTG 660

CAAGCAAAAG AGGTGCTATC GAAACTCCCT ACCTTAGTTG AAACAACGTT AAAAGAAACA 720

GAGAAAATCA CAGTCTGTGG AGACACCCAC GGCCAGTATT ACGACCTCCT GAACATATTT 780

GAGTTGAATG GGCTGCCAGC AGAAACGAAT CCCTATATAT TCAACGGGGA TTTTGTTGAC 840

CGCGGCTCCT TCTCGGTGGA GGTGATATTA ACGCTGTTTG GTTTTAAGCT GCTATACCCA 900

GACCATTTCC ACCTACTTCG AGGGAACCAC GAAACTGATA ATATGAACCA AATTTACGGG 960

TTTGAAGGCG AAGTGAAGGC CAAATACACA GCCCAGATGT TTGAGCTCTT CAGCGAAGTG 1020

TTTGAGTGGC TTCCTCTGGC GCAGTGCATC AACGGCAAAG TGTTGATAAT GCACGGTGGG 1080

CTTTTCAGTG AAGATGGAGT AACGTTAGAT GATATCAGGA AGATCGAAAG GAATCGGCAA 1140

CCTCCAGATT CAGGTCCCAT GTGTGACTTA CTCTGGTCAG ACCCTCAACC TCAGAATGGC 1200

AGGTCGATCA GCAAACGGGG CGTGAGCTGC CAGTTCGGGC CCGACGTCAC CCAAAGCTTC 1260

CTGGAACGCA ACCATTTAGA CTACATCATC CGCAGCCACG AAGTCAAGCC TGAGGGATAT 1320

GAGGTGGCCC ACGACGGCAA GTGCGTCACC GTGTTCTCGG CCCCCAACTA CTGTGACCAG 1380

ATGGGCAATA AAGGTTCCTA CATCCACTTG AAAGGCTCAG ACCTGCGGCC GGAATTCCAC 1440

CAGTTCACAG CAGTGCCTCA TCCAAACGTC AAGCCAATGA TGTATGCCAA CTCGCTGCTA 1500

CAGCTGGGGA TGATGTGA 1518

Domain Profile

S: 2     kvsiefikklvndlklkkkllrkkavailvsvadvlfklevelennskedvkitvcGdth  61

         kv+ ef+k+l++++k++kkl+rk+a++ilv+ ++vl+kl +++e+++ke++kitvcGdth

Q: 191   KVTPEFMKELMQWYKDQKKLHRKCAYQILVQAKEVLSKLPTLVETTLKETEKITVCGDTH  250

         7899********************************************************

S: 62    GqfydllnifelnGlpseknpylfnGdfvdrGsfsveviltlfglkllyPdhffllrGnh  121

         Gq+ydllnifelnGlp+e+npy+fnGdfvdrGsfsveviltlfg+kllyPdhf+llrGnh

Q: 251   GQYYDLLNIFELNGLPAETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNH  310

         ************************************************************

S: 122   esdnmnkiyGfegevkakytaklyelfaevfewlPlaqlingkvlvmhGGlfsedgvtld  181

         e+dnmn+iyGfegevkakyta+++elf+evfewlPlaq+ingkvl+mhGGlfsedgvtld

Q: 311   ETDNMNQIYGFEGEVKAKYTAQMFELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLD  370

         ************************************************************

S: 182   dirkiernaqPPeeGalcellWsdPqeanGrgvskrGvglqfGpdvtkrfleenkldyii  241

         dirkiern+qPP++G++c+llWsdPq++nGr++skrGv++qfGpdvt+ fle n+ldyii

Q: 371   DIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTQSFLERNHLDYII  430

         ************************************************************

S: 242   rshevkaegveveqkgklvtvfsapnycdsqgnlasvihvrnddlrliietfeavehpdv  301

         rshevk eg+ev+++gk+vtvfsapnycd++gn++s+ih++++dlr+ +++f+av+hp+v

Q: 431   RSHEVKPEGYEVAHDGKCVTVFSAPNYCDQMGNKGSYIHLKGSDLRPEFHQFTAVPHPNV  490

         ************************************************************

S: 302   kpmaysngllgl  313

         kpm y+n+ll+l

Q: 491   KPMMYANSLLQL  502

         *********987

Domain Sequence
(FASTA)

KVTPEFMKEL MQWYKDQKKL HRKCAYQILV QAKEVLSKLP TLVETTLKET EKITVCGDTH 60

GQYYDLLNIF ELNGLPAETN PYIFNGDFVD RGSFSVEVIL TLFGFKLLYP DHFHLLRGNH 120

ETDNMNQIYG FEGEVKAKYT AQMFELFSEV FEWLPLAQCI NGKVLIMHGG LFSEDGVTLD 180

DIRKIERNRQ PPDSGPMCDL LWSDPQPQNG RSISKRGVSC QFGPDVTQSF LERNHLDYII 240

RSHEVKPEGY EVAHDGKCVT VFSAPNYCDQ MGNKGSYIHL KGSDLRPEFH QFTAVPHPNV 300

KPMMYANSLL QL 312

Keyword

Complete proteome; Hydrolase; Iron; Metal-binding; Reference proteome; Repeat; TPR repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0046872	; F:metal ion binding
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR004843	; Metallo_PEstase_dom.
IPR013235	; PPP_dom.
IPR006186	; Ser/Thr-sp_prot-phosphatase.
IPR011236	; Ser/Thr_PPase_5.
IPR001440	; TPR-1.
IPR013026	; TPR-contain_dom.
IPR011990	; TPR-like_helical.
IPR019734	; TPR_repeat.

Pfam

PF00149	; Metallophos; 1.
PF08321	; PPP5; 1.
PF00515	; TPR_1; 1.

SMARTs

SM00156	; PP2Ac; 1.
SM00028	; TPR; 3.

Prosites

PS00125	; SER_THR_PHOSPHATASE; 1.
PS50005	; TPR; 3.
PS50293	; TPR_REGION; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013