EKS-ANC-00485

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00485

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/BRD	N/A	N/A	N/A	N/A	N/A

Status

Unreviewed

Ensembl Protein

ENSACAP00000017011

UniProt Accession

G1KTQ0;

Protein Name

Protein Synonyms/Alias

Gene Name

BRD4

Gene Synonyms/Alias

BRD4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000017270	ENSACAP00000017011	ENSACAT00000017346

Organism

Anolis carolinensis

Functional Description

Protein Length

1378

Protein Sequence
(FASTA)

MSTESSPGTR LRNLPVMGDG LEATQMSTTQ AQAQPQQGNT LSTNPSPPET SNPNKPKRMT 60

NQLQYLLKVV LKTLWKHQFS WPFQQPVDAV KLQLPDYYKI IKTPMDMGTI KKRLENNYYW 120

NAQECIQDFN TMFTNCYIYN KPGDDIVLMA EALEKLFLQK ISEMTQEETE IVIVQTKGRG 180

RGRKETVTSK AGASAVQNTT QTSSPSQTPA PQQNPQPAQT THSFPSMTPD LIVQTPVMTV 240

VPAQPPAPPP PPPPPPPPPP PPPASAPQPI QTHPPIIPTA AQPMKTKKGV KRKADTTTPT 300

TIDPVHESSS LPAEPKPAKA GPRRESRPVK PPKKDVPDSQ QHVVEKSSSN KVSEQLKYCS 360

GIIKEMFAKK HAAYAWPFYK PVDVEALGLH DYRDIIKHPM DLSTIKSKLE NRDYRDAQEF 420

AADVRLMFSN CYKYNPPDHE VVAMARKLQD VFEMRFAKMP DEPEEPVIPA SSPVAVQPPP 480

KVPPPSSSDS SSDSSSDSDS SSDDSEEERA QRLAELQEQL KAVHEQLAAL SQPQQNKPKK 540

KEKDKKEKKK EKHKKKDEVE ENKKNKTKDP LPKKAKKNNG NNTNSSSKKE PVTVKNAKPA 600

PVYESEEEEK CKPMSYEEKR QLSLDINKLP GEKLGRVVHI IQSREPSLKN SNPDEIEIDF 660

ETLKASTLRE LERYVTSCLR KKRKPQAEKV DVIAGSSKMK GFSSSESEST SESSSSDSED 720

SETEIPPKLR KKGHTGREQK KHHHHHHQQV QQQPQPPPQQ QLQPQQLPPP STAVPPQTVA 780

SVKSSPPAFV PAQIPIMEHP LPGNMFDSIS HFTQPIMQLP PPEMPPHIPQ QPEHSTPPHL 840

NQHTVVSPPA LHNALPQQPS RPSNRAAALP LKPSRPPAVS PALNQQPMLP QPPLPQPPQV 900

LLEDEEPPAP HHTLPLSNSQ MQLYLQQLHK VQPQTSLLPS VKVQSQPQPS LQPSHPPVQQ 960

LQHQPQPRPV HMQPMQFASH MPQPQPPPQQ HLPPQQPQQP PQQPPKPQQV IQHHPSPRHH 1020

KPDLYSTGHL REAPSPLMMH SPQMPQFQGL PHQSPPQPNV QPKKQVRGHY GCQVPRLYMG 1080

MNMRCGTGTL GRRMGLMQEL RAASVVQSQP MVKEEKMQSP VIRNETFSPA LRQDPPKHPE 1140

SIKPPTHVQQ RTEMKPVDGG RPVIRPPEQN APPGVQEKER QKQEPKTPVA PKKDLKIKNM 1200

GSWASLVQKH PTAPSSTAKS SSDSFEHFRR AAREKEEREK ALKAQAEQAE KEKERQRREQ 1260

ERMRSREEED ALEQARRVHE EVRRRQEQQQ QQQQQQPQHQ PPPPPPPQQP QPPPQVSATA 1320

SAPQAQSSQP HTSQSMLDQQ REMLRKREQE RRRREAMAAT IDMNFQSDLL AIFEENLF 1378

Nucleotide Sequence
(FASTA)

ATGTCTACCG AGAGCAGCCC TGGGACAAGA CTGAGAAATT TACCAGTAAT GGGGGATGGA 60

CTAGAAGCTA CACAAATGTC TACAACACAG GCACAAGCCC AACCCCAACA AGGCAATACC 120

CTATCCACTA ATCCATCACC TCCAGAGACC TCCAATCCTA ACAAACCCAA GCGCATGACC 180

AACCAGCTGC AGTATCTGCT CAAAGTGGTG CTCAAGACAC TATGGAAACA CCAGTTTTCA 240

TGGCCTTTCC AGCAGCCTGT GGATGCTGTC AAACTACAAC TCCCTGATTA TTATAAAATT 300

ATTAAAACTC CTATGGATAT GGGAACAATA AAGAAACGGT TAGAGAATAA CTACTACTGG 360

AATGCTCAAG AATGTATCCA GGACTTCAAT ACAATGTTTA CAAATTGTTA CATCTATAAT 420

AAGCCAGGGG ATGATATTGT TCTCATGGCA GAAGCTCTAG AAAAACTCTT CCTTCAAAAA 480

ATCTCTGAAA TGACCCAGGA AGAAACGGAA ATAGTTATAG TCCAGACAAA AGGAAGGGGA 540

CGTGGCAGAA AAGAAACAGT TACATCCAAG GCAGGAGCTT CAGCGGTACA GAACACAACT 600

CAAACTTCAT CCCCATCACA GACTCCAGCT CCACAACAGA ATCCTCAGCC TGCTCAAACA 660

ACTCATTCCT TTCCTTCTAT GACCCCCGAT CTTATTGTCC AGACACCAGT AATGACTGTG 720

GTGCCTGCCC AGCCTCCTGC GCCTCCTCCT CCTCCTCCTC CCCCTCCCCC TCCCCCTCCC 780

CCTCCTCCAG CTTCTGCCCC CCAGCCTATT CAGACTCACC CACCAATAAT CCCAACAGCT 840

GCACAGCCCA TGAAGACAAA AAAAGGTGTG AAGAGGAAAG CAGACACTAC TACCCCAACA 900

ACAATAGATC CAGTCCACGA GTCCTCATCA TTGCCTGCAG AACCCAAGCC TGCCAAGGCA 960

GGTCCACGAA GGGAAAGCCG ACCTGTGAAA CCTCCAAAAA AGGATGTTCC AGATTCTCAG 1020

CAGCACGTGG TAGAAAAAAG TAGCAGTAAC AAAGTATCAG AGCAATTAAA GTATTGTAGC 1080

GGTATCATAA AAGAAATGTT TGCTAAGAAG CACGCAGCCT ATGCTTGGCC CTTCTACAAA 1140

CCTGTGGATG TGGAAGCACT TGGGCTTCAT GATTATCGTG ATATCATTAA ACATCCCATG 1200

GATCTGAGCA CAATTAAATC CAAACTAGAG AATCGGGATT ACAGAGATGC TCAGGAATTT 1260

GCGGCTGATG TCCGATTGAT GTTTTCCAAT TGTTATAAGT ATAACCCTCC TGATCATGAA 1320

GTGGTTGCAA TGGCTCGAAA ATTGCAGGAT GTATTTGAAA TGCGTTTTGC TAAAATGCCA 1380

GATGAACCCG AAGAACCTGT GATTCCAGCT TCCTCTCCAG TAGCGGTGCA GCCCCCACCC 1440

AAAGTGCCGC CACCTTCATC CAGCGATAGC AGCAGTGACA GTTCCTCTGA TAGTGACAGT 1500

TCGTCAGATG ATTCTGAAGA AGAGCGAGCT CAGCGACTAG CAGAACTCCA GGAACAACTT 1560

AAAGCAGTGC ATGAGCAGTT GGCTGCTCTG TCCCAGCCGC AACAGAACAA ACCAAAGAAA 1620

AAAGAGAAAG ACAAGAAAGA AAAGAAAAAA GAAAAGCACA AAAAGAAGGA CGAAGTAGAA 1680

GAAAACAAGA AAAATAAAAC AAAGGATCCA CTACCTAAAA AGGCCAAGAA GAATAATGGC 1740

AACAATACCA ACTCAAGTAG TAAGAAGGAG CCTGTGACTG TGAAGAATGC CAAGCCAGCT 1800

CCTGTTTATG AATCTGAGGA GGAGGAGAAA TGTAAGCCAA TGTCTTATGA GGAAAAAAGA 1860

CAGTTGAGCC TGGACATTAA CAAGCTCCCT GGTGAAAAGC TAGGCCGGGT TGTCCATATC 1920

ATCCAGTCAA GAGAACCCTC TCTCAAAAAC TCCAATCCTG ATGAGATTGA AATTGACTTT 1980

GAGACATTAA AGGCATCCAC GTTGCGGGAG CTGGAGAGAT ATGTAACATC TTGTTTACGG 2040

AAAAAGAGGA AACCCCAAGC AGAGAAAGTG GATGTAATTG CTGGTTCTTC TAAAATGAAG 2100

GGGTTCTCCT CCTCAGAGTC TGAGAGCACC AGTGAGTCCA GCTCCTCCGA CAGTGAAGAT 2160

TCAGAAACAG AAATCCCACC TAAACTTAGG AAAAAAGGAC ATACTGGACG AGAACAGAAA 2220

AAACATCACC ACCATCACCA TCAACAAGTG CAGCAGCAGC CGCAGCCACC ACCACAACAG 2280

CAGTTACAAC CACAACAGCT ACCACCACCC TCCACAGCTG TCCCGCCGCA AACAGTTGCT 2340

TCAGTCAAGT CCTCTCCTCC AGCTTTTGTT CCAGCGCAAA TCCCAATTAT GGAGCATCCG 2400

CTCCCAGGGA ACATGTTCGA CAGTATCTCT CATTTCACTC AACCTATTAT GCAGCTTCCT 2460

CCACCAGAGA TGCCGCCCCA TATTCCTCAG CAGCCTGAGC ACAGCACTCC TCCTCATTTG 2520

AATCAACATA CGGTTGTGTC CCCTCCAGCT TTGCACAATG CTCTGCCTCA GCAGCCCTCG 2580

AGACCCAGTA ATCGAGCTGC AGCGCTCCCC CTTAAACCAT CTCGACCCCC TGCAGTTTCG 2640

CCGGCCCTTA ACCAGCAGCC CATGCTCCCC CAGCCTCCGC TTCCCCAGCC ACCCCAAGTG 2700

CTGCTAGAGG ATGAAGAACC CCCTGCGCCT CACCATACTC TGCCGCTCAG TAACAGCCAG 2760

ATGCAGCTGT ACCTGCAGCA ATTGCACAAA GTGCAGCCAC AGACTTCTCT CCTCCCTTCA 2820

GTGAAGGTCC AGTCACAGCC TCAGCCGTCC TTGCAGCCTT CTCATCCTCC GGTTCAGCAG 2880

TTACAGCACC AACCGCAGCC GAGGCCAGTA CATATGCAAC CCATGCAGTT TGCGTCCCAC 2940

ATGCCTCAGC CTCAGCCGCC TCCACAGCAG CATCTCCCCC CACAGCAGCC GCAGCAGCCA 3000

CCTCAACAGC CGCCAAAGCC CCAACAGGTC ATCCAGCATC ATCCATCACC GAGACATCAC 3060

AAGCCAGACC TCTACTCAAC TGGTCATTTG AGAGAAGCGC CTTCCCCTCT CATGATGCAT 3120

TCCCCACAGA TGCCACAGTT CCAGGGGCTG CCACACCAGT CTCCGCCTCA ACCAAATGTC 3180

CAGCCAAAAA AACAGGTAAG AGGACATTAT GGATGTCAGG TTCCCAGATT GTATATGGGC 3240

ATGAACATGA GATGTGGAAC TGGAACATTG GGAAGAAGAA TGGGTTTAAT GCAAGAACTG 3300

AGAGCAGCTT CTGTAGTTCA GTCGCAACCT ATGGTAAAAG AGGAAAAGAT GCAGTCGCCA 3360

GTCATTCGAA ATGAGACTTT CAGTCCAGCC TTGCGGCAAG ATCCTCCGAA GCACCCAGAG 3420

AGCATCAAGC CACCTACGCA TGTCCAGCAG CGAACAGAAA TGAAGCCAGT AGATGGTGGA 3480

CGACCTGTTA TAAGACCCCC AGAGCAAAAT GCACCACCAG GAGTCCAAGA GAAAGAGAGA 3540

CAGAAGCAGG AACCAAAAAC ACCCGTTGCC CCTAAAAAGG ACCTGAAGAT AAAGAATATG 3600

GGCTCCTGGG CGAGCTTAGT GCAGAAGCAT CCCACTGCAC CATCCTCTAC GGCAAAATCA 3660

AGCAGTGACA GCTTTGAGCA CTTCAGGAGG GCAGCACGGG AAAAAGAAGA GCGAGAGAAG 3720

GCCTTGAAAG CTCAGGCAGA GCAAGCAGAG AAGGAGAAGG AGCGGCAGCG GCGGGAGCAG 3780

GAGCGAATGA GGAGTCGTGA AGAGGAGGAT GCACTGGAGC AAGCTCGCCG AGTTCATGAA 3840

GAAGTCCGGC GGCGCCAGGA GCAGCAGCAA CAGCAGCAGC AGCAGCAGCC CCAGCATCAA 3900

CCTCCCCCAC CACCCCCACC ACAGCAGCCC CAGCCCCCGC CGCAGGTGTC AGCCACAGCC 3960

TCCGCTCCTC AAGCGCAGAG CTCTCAGCCC CACACTTCTC AGTCCATGCT GGACCAACAG 4020

AGAGAGATGC TCAGAAAACG AGAGCAGGAA CGAAGGCGCA GAGAGGCAAT GGCAGCTACT 4080

ATTGACATGA ATTTCCAGAG TGATTTGTTG GCAATATTTG AAGAGAATCT TTTCTAA 4137

Domain Profile

N/A

Domain Sequence
(FASTA)

N/A

Keyword

Bromodomain; Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0000794	; C:condensed nuclear chromosome
GO:0005737	; C:cytoplasm
GO:0000790	; C:nuclear chromatin
GO:0003677	; F:DNA binding
GO:0007059	; P:chromosome segregation
GO:0044154	; P:histone H3-K14 acetylation
GO:0043983	; P:histone H4-K12 acetylation
GO:0043388	; P:positive regulation of DNA binding
GO:0010971	; P:positive regulation of G2/M transition of mitotic cell cycle
GO:0032968	; P:positive regulation of transcription elongation from RNA polymerase II promoter
GO:0006468	; P:protein phosphorylation
GO:0000114	; P:regulation of transcription involved in G1 phase of mitotic cell cycle

KEGG

InterPros

IPR001487	; Bromodomain.
IPR018359	; Bromodomain_CS.

Pfam

PF00439

; Bromodomain; 2.

SMARTs

SM00297

; BROMO; 2.

Prosites

PS00633	; BROMODOMAIN_1; 2.
PS50014	; BROMODOMAIN_2; 2.

Prints

PR00503

; BROMODOMAIN.

Created Date

20-Feb-2013