EKS-ANC-00162

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00162

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TTK	446.6	2.7E-134	534	798	265

Status

Unreviewed

Ensembl Protein

ENSACAP00000021310

UniProt Accession

G1KTV1;

Protein Name

Protein Synonyms/Alias

Gene Name

TTK

Gene Synonyms/Alias

TTK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000017368	ENSACAP00000017126	ENSACAT00000017463
ENSACAG00000017368	ENSACAP00000021310	ENSACAT00000023080

Organism

Anolis carolinensis

Functional Description

Protein Length

861

Protein Sequence
(FASTA)

MQEEDINGKG LFVASIMSRV RDLKSKYKNE DNITDELSKI SADTTDNSGT VNRIMMTANN 60

PEDWMHFLLK LEKKGSPQTD ISLLNRLIGR YSQAIASLSA EKYSQNESYA HILVRFAELK 120

AMEEPEEARD QFHLARLNSK KFAFVHIAFA QFELSQGNVK KAKQLLEKAV ESRAVPVEML 180

ETALRNLSLR KKILLPIEEK ENLTVNYVFT VPNSHNLVGN VLNRKNNGDS EISANISNFC 240

HGQKNDSPQE AELDLGGRNP LKQLNKANPV CTFGRVPIKL VSDSESESDD TDDSVKKEMP 300

HLTKRQISAT SLNTLSLHEA KSNRSDSYLP QNLKCLPNRK LIELHLSDDE SLEAATNTSL 360

TLKNKFDSNY VIQRKEIEDQ QDEPSITESN CPERNDQREN EQSRLHCIAT GNKWFHPEAL 420

HKRNSEIHSK HQKLSLKEST LQRCSPPETT SERKSQADVG TTPSNKKLHN YFGCFSTPSI 480

RNDFPFAGSA GTPYNHFPYL QTHTPKPLFS VHTPLQIPAS VPSNECIAVK GKLYSVLKQI 540

GTGGSSKVFQ VLDEKKQLYA IKYVNLEEAD QQTIESYKNE IAHLNKLQQH SDKIIRLYDY 600

EIGAKSIYMV LECGNIDLNS WLKKKKAINP WERKSYWKNM LEAVHAIHQH GIVHSDLKPA 660

NFLLVDGMLK LIDFGIANQM QPDVTSIVKD SQIGTLNYMP PEAINSSCGE NSQPRSKISP 720

KSDVWSLGCI LYSMTYGRTP FQHITNQITK LHAIIDPNFE IAFPDIPEKD LQDVLKHCLV 780

RNPKQRISVA ELLVHPYVQI QRHSSTKGTT EEMKRILGHL IGLNSPNSIS RAARTLYEQC 840

SNGEGLDVSA FASCDHQKAR S 861

Nucleotide Sequence
(FASTA)

ATGCAGGAAG AAGATATAAA TGGAAAAGGT CTGTTTGTCG CTTCTATTAT GAGTAGAGTA 60

AGAGACTTAA AAAGCAAATA TAAAAACGAG GACAATATTA CAGATGAACT TAGTAAGATA 120

TCAGCTGATA CAACAGATAA CTCTGGAACT GTTAATCGGA TCATGATGAC TGCAAATAAC 180

CCTGAAGACT GGATGCATTT TTTACTAAAA TTAGAGAAAA AGGGCAGTCC TCAGACTGAC 240

ATCAGCTTAT TGAATAGATT AATTGGTCGT TACAGTCAAG CCATAGCATC ATTATCTGCA 300

GAAAAATATA GCCAGAATGA AAGTTATGCT CACATTCTGG TTAGGTTTGC AGAACTAAAG 360

GCTATGGAGG AACCAGAAGA GGCACGTGAT CAGTTCCATC TTGCTAGACT GAACAGCAAG 420

AAATTTGCTT TCGTCCACAT AGCTTTTGCG CAGTTTGAAC TCTCCCAAGG GAATGTAAAA 480

AAGGCTAAAC AGCTTCTTGA AAAAGCGGTG GAATCTAGAG CAGTTCCAGT AGAGATGTTG 540

GAAACTGCTC TAAGAAACTT AAGCTTACGA AAAAAGATCC TACTTCCTAT TGAAGAAAAG 600

GAGAATTTGA CAGTAAATTA TGTATTTACA GTCCCAAACT CTCACAATCT AGTTGGAAAT 660

GTTCTGAATA GAAAAAACAA TGGTGATTCT GAGATTTCTG CCAATATTTC CAACTTTTGT 720

CATGGGCAGA AAAATGATTC CCCGCAAGAA GCTGAATTGG ACTTGGGTGG ACGCAACCCT 780

CTGAAGCAAC TAAACAAAGC AAATCCGGTG TGCACCTTTG GAAGAGTTCC TATCAAATTA 840

GTAAGTGATA GTGAGAGTGA GAGTGATGAT ACAGATGACT CTGTGAAGAA GGAGATGCCA 900

CATCTTACAA AAAGGCAAAT ATCTGCTACC AGTCTGAATA CTTTGTCACT ACATGAAGCA 960

AAATCAAACA GAAGTGATTC CTATCTGCCA CAGAACTTGA AGTGTTTACC AAACAGAAAG 1020

CTTATAGAAC TGCACCTATC TGATGATGAG AGCTTGGAAG CAGCTACCAA TACCTCTCTA 1080

ACATTAAAAA ATAAATTTGA TTCCAACTAC GTCATTCAAA GAAAAGAAAT TGAAGATCAG 1140

CAGGACGAGC CAAGCATCAC TGAATCAAAC TGTCCAGAAA GAAATGACCA AAGGGAAAAT 1200

GAACAATCTA GATTACACTG TATTGCAACT GGAAATAAAT GGTTTCATCC TGAAGCTTTG 1260

CATAAAAGAA ACTCAGAGAT ACACAGTAAA CATCAGAAAT TATCACTAAA AGAGTCAACT 1320

TTACAACGAT GTTCACCACC AGAAACTACT TCAGAAAGAA AGAGCCAGGC AGATGTTGGT 1380

ACAACACCTA GCAACAAAAA GCTGCACAAT TATTTTGGCT GTTTCAGTAC TCCATCCATA 1440

AGAAATGATT TTCCTTTTGC GGGAAGTGCA GGCACCCCAT ACAACCATTT TCCGTATTTG 1500

CAGACCCATA CTCCAAAACC TCTTTTCTCA GTGCACACTC CATTACAGAT TCCAGCTTCT 1560

GTACCGTCAA ATGAATGCAT TGCTGTTAAA GGAAAATTGT ACTCGGTGCT TAAACAAATC 1620

GGAACAGGAG GCTCGAGTAA GGTATTCCAA GTACTTGATG AAAAAAAGCA GCTTTATGCC 1680

ATCAAATATG TGAATCTGGA AGAGGCTGAT CAACAAACAA TAGAAAGCTA TAAAAATGAG 1740

ATTGCACATT TAAATAAACT CCAGCAACAC AGTGATAAGA TCATTCGGCT TTATGACTAT 1800

GAAATTGGAG CAAAAAGTAT CTATATGGTG TTGGAATGTG GAAATATTGA TCTGAACAGC 1860

TGGCTTAAAA AGAAGAAGGC AATTAATCCA TGGGAGCGGA AAAGTTATTG GAAAAATATG 1920

TTAGAAGCTG TCCATGCAAT CCACCAACAT GGTATTGTTC ATAGTGATCT CAAACCAGCA 1980

AATTTCCTTC TAGTGGACGG AATGTTAAAA TTAATAGACT TTGGCATTGC AAACCAGATG 2040

CAGCCAGACG TGACTAGTAT TGTTAAAGAT TCACAGATTG GGACTCTAAA TTATATGCCA 2100

CCAGAGGCAA TCAATTCATC CTGTGGAGAA AATAGCCAAC CAAGATCAAA GATCAGTCCA 2160

AAAAGTGATG TCTGGTCTTT AGGCTGTATT TTATATTCTA TGACCTATGG AAGAACTCCA 2220

TTTCAACACA TAACAAATCA AATCACAAAA CTTCATGCCA TAATTGATCC TAATTTTGAA 2280

ATAGCTTTTC CTGATATTCC AGAAAAAGAT CTCCAGGATG TCTTGAAGCA TTGTTTGGTA 2340

AGAAATCCTA AACAAAGAAT ATCAGTTGCT GAATTGTTGG TTCATCCTTA TGTACAAATC 2400

CAAAGGCATT CAAGTACAAA AGGAACCACA GAGGAAATGA AACGTATTCT TGGTCATCTT 2460

ATTGGCTTGA ACTCTCCTAA TTCCATTTCT AGGGCTGCTA GAACTTTATA CGAGCAGTGC 2520

AGCAATGGTG AAGGCTTAGA TGTGTCTGCT TTTGCAAGTT GTGATCATCA GAAAGCACGG 2580

AGT 2583

Domain Profile

S: 1     yeilkklGsGGsskvfkvksekkrvyalkvvdleaaddqtidgykneielleklqdqs.k  59

         y++lk++G+GGsskvf+v++ekk+ ya+k+v+le+ad+qti++yknei+ l+klq++s k

Q: 534   YSVLKQIGTGGSSKVFQVLDEKKQLYAIKYVNLEEADQQTIESYKNEIAHLNKLQQHSdK  593

         99********************************************************9*

S: 60    virlydyeledsllylvmecGdidlnkilkkkksiepdyelvsyykemleavkvihqhGi  119

         +irlydye++ + +y+v+ecG+idln++lkkkk+i+p +e++sy+k+mleav+ ihqhGi

Q: 594   IIRLYDYEIGAKSIYMVLECGNIDLNSWLKKKKAINP-WERKSYWKNMLEAVHAIHQHGI  652

         *************************************.**********************

S: 120   vhsdlkPanfllvdGilklidfGianavaedttsivkesqvGtvnylaPealkdmsssqs  179

         vhsdlkPanfllvdG+lklidfGian++++d tsivk+sq+Gt+ny++Pea++

Q: 653   VHSDLKPANFLLVDGMLKLIDFGIANQMQPDVTSIVKDSQIGTLNYMPPEAINS------  706

         ***************************************************963......

S: 180   sereaekskikvsrksdvwslGcilylllygktPfgsirnqvskllaiinPdveiefPei  239

         s  e++++++k+s+ksdvwslGcily ++yg+tPf++i nq++kl+aii+P+ ei fP+i

Q: 707   SCGENSQPRSKISPKSDVWSLGCILYSMTYGRTPFQHITNQITKLHAIIDPNFEIAFPDI  766

         345899******************************************************

S: 240   tsniekslvellkaclkrnPkkrisvdellsspfv  274

         +   ek+l+++lk cl+rnPk+risv ell +p+v

Q: 767   P---EKDLQDVLKHCLVRNPKQRISVAELLVHPYV  798

         *...*****************************96

Domain Sequence
(FASTA)

YSVLKQIGTG GSSKVFQVLD EKKQLYAIKY VNLEEADQQT IESYKNEIAH LNKLQQHSDK 60

IIRLYDYEIG AKSIYMVLEC GNIDLNSWLK KKKAINPWER KSYWKNMLEA VHAIHQHGIV 120

HSDLKPANFL LVDGMLKLID FGIANQMQPD VTSIVKDSQI GTLNYMPPEA INSSCGENSQ 180

PRSKISPKSD VWSLGCILYS MTYGRTPFQH ITNQITKLHA IIDPNFEIAF PDIPEKDLQD 240

VLKHCLVRNP KQRISVAELL VHPYV 265

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR011990	; TPR-like_helical.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013