EKS-ANC-00380

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ANC-00380

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	355.1	2.6E-106	609	864	256

Status

Unreviewed

Ensembl Protein

ENSACAP00000017562

UniProt Accession

H9GPS4;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP3K6

Gene Synonyms/Alias

MAP3K6;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSACAG00000017835	ENSACAP00000017562	ENSACAT00000017908

Organism

Anolis carolinensis

Functional Description

Protein Length

1305

Protein Sequence
(FASTA)

ALTPSKPLAG SRGGGGGGSP RARSRAVLYV STEDSGEPLP LRCLRDACAR LPDARLHALP 60

FGTVMLGDTP HLDRFYNADV VVVEMSNSLC QPSLFYHLGV RESFSMTNNI LLCCYTDLPE 120

FQALREEVLQ KNSDGNGSYT FIPYVVTAQN KVFCCDASTM MCLSELYQPS FNVEAFLTPL 180

TTQLATLLED TSTSSCGYIR EMIRRDIRRA RERYSGEQLS RELNGIQQRL DSVECLSLDI 240

VMNFLLSYRD AQDCDAIITL VETLQALPTC NIAEQHNICF HYAFALDRRN HPGDREKALS 300

VLLPLVERPE GAAPDLYCMC GRIYKDMFID SGFTDAEKRD QAFFWWYHKA FLTEPSLHAG 360

INSVVFLIAA GHKFETSPQL RQIGMKLSCV LGRKGCLEKM QQYWDVGFYL GASILTGDVD 420

KIIQASEILY KLNAPVWYLI SIKETYTIYS HFTAPPDTWS PKQELVDFWL GFVMECCQPF 480

VSTEQCLVLI LDLGRVLQPA RLCICDQETQ KSVTLSHICS LEEEGVSTWT FSVSSIRGIS 540

ISKCDERCCF LYVLHTAEDF QLYFPSQHHC QWFCNLIRSF MAEMGEEADG CSSPEELEYD 600

YEYTEVGDKV VLGKGTYGVV YAGRDLSNQV RIAIKEIPER DSRYSQPLHE EIALHKRLKH 660

KNIVRYLGSV SQDGYLKIFM EEVPGGSLSS LLRSMWGPLK DNEPTIVYYT KQILEGLRYL 720

HDNQIVHRDI KGDNVLINTY NGVLKISDFG TSKRLAGISP SAETFTGTLQ YMAPEVIDQG 780

PRGYGKPADI WSLGCTIIEM ATGKPPFFEL GSPQAAMFKV GMFKIHPEVP SSMSDEAKAF 840

ILSCFEADPD KRATAAALLQ EPFLKSTSRK KARSPVMMTV QFVTSDFFHF FCIAMPLPLI 900

LLYFSQVLPY KSALPPSLVS ICKYETYKTY KLHPTYNFKT KICTFLIGTK APEEAGHFDL 960

SLSSSSHEES GCLFLLKKDS ERRVTLFKVL TEELPSIAAA LHKAQEENPL SLELVSQLVS 1020

CLKGYIRSPS RKQLAQDLLR LQASLQAEGR GLCQLQVPLF TFQDTVKQAL RKLQIKPHWV 1080

FALDNLMGQA VQAAFTILLT EGRAKKLVNL MGFVAHQCQL DVGEHGPFQP SHAKITLEDL 1140

TLKGSMDTPS SGIGTTTNSW VDSQHALRGR LPLMAQLHQL QAETRRLQWK LIEKEREFQR 1200

LLQEALQAVK QDGHALQSPK PTGIKEKPIT HQIRKEEEAA DPRLAAWLEK QGVDKATIAK 1260

LSGHGFTLPI LLNCATIDDL RYTCIRGGMV CRIWRALANH RQALG 1305

Nucleotide Sequence
(FASTA)

GCCCTCACGC CCAGCAAGCC CCTCGCGGGG TCCCGGGGTG GAGGGGGAGG GGGCTCTCCC 60

AGGGCCCGCT CCCGCGCCGT GCTCTACGTC TCCACCGAGG ACTCGGGCGA GCCGCTCCCG 120

CTCCGCTGCC TCCGCGACGC CTGCGCCCGC CTGCCCGACG CCCGCCTCCA CGCCCTCCCC 180

TTCGGCACCG TCATGCTCGG AGACACGCCA CACCTCGACC GCTTCTACAA CGCAGACGTG 240

GTCGTGGTGG AGATGAGCAA CAGCCTGTGC CAGCCCTCGC TCTTCTACCA CTTGGGCGTG 300

CGAGAGAGCT TCAGCATGAC CAACAACATC CTCCTCTGCT GTTACACCGA CCTGCCCGAG 360

TTCCAGGCCC TCCGGGAAGA AGTTTTACAA AAGAACTCGG ACGGCAACGG CAGCTACACC 420

TTCATCCCTT ACGTGGTGAC GGCCCAGAAC AAGGTCTTCT GCTGTGACGC CAGCACCATG 480

ATGTGCCTGA GTGAGCTCTA CCAGCCCAGC TTCAACGTGG AGGCCTTCCT GACCCCGCTG 540

ACCACGCAGC TGGCCACTCT GCTCGAGGAC ACCTCCACCA GCTCCTGCGG CTACATCCGG 600

GAGATGATCC GGAGGGACAT CCGGAGGGCC CGCGAGCGGT ACAGCGGGGA GCAGCTGAGC 660

CGGGAGCTGA ACGGCATCCA GCAGCGCCTG GACAGCGTGG AGTGCCTCAG CCTCGACATC 720

GTCATGAACT TCCTCCTCTC CTACCGCGAT GCTCAGGACT GTGATGCCAT CATCACGCTG 780

GTGGAGACCC TGCAGGCCCT GCCAACGTGC AACATCGCCG AGCAGCACAA CATCTGCTTC 840

CACTATGCCT TTGCTCTCGA CAGGCGGAAC CACCCCGGGG ACCGCGAGAA GGCCCTGTCC 900

GTCCTCCTGC CGCTGGTGGA ACGGCCGGAA GGGGCAGCCC CGGACCTGTA CTGCATGTGC 960

GGACGCATCT ACAAGGACAT GTTCATCGAT TCGGGTTTCA CTGACGCCGA GAAAAGAGAC 1020

CAAGCCTTCT TCTGGTGGTA CCACAAGGCC TTTTTGACCG AGCCGAGCCT TCACGCCGGA 1080

ATTAACTCGG TTGTCTTCCT CATTGCGGCG GGACACAAGT TTGAAACTTC TCCGCAGCTT 1140

CGGCAGATTG GTATGAAGTT GAGTTGTGTC CTGGGCCGGA AGGGCTGCTT GGAAAAAATG 1200

CAACAATACT GGGACGTGGG TTTTTACCTG GGTGCAAGTA TCTTAACCGG CGACGTTGAC 1260

AAAATCATCC AGGCTTCGGA GATCCTCTAC AAGCTCAACG CCCCTGTCTG GTACTTGATC 1320

TCTATCAAAG AAACCTATAC CATCTACAGT CATTTCACGG CTCCTCCAGA CACGTGGTCT 1380

CCCAAACAGG AGCTGGTGGA CTTCTGGCTG GGCTTTGTGA TGGAGTGCTG CCAGCCTTTT 1440

GTCTCTACCG AACAGTGTCT GGTGTTGATC CTCGACCTGG GCCGGGTCTT GCAACCAGCC 1500

CGGCTCTGTA TCTGCGATCA AGAGACTCAA AAATCCGTGA CCCTGAGTCA CATCTGCTCC 1560

CTGGAAGAGG AAGGCGTTTC TACTTGGACA TTTTCAGTTT CTTCCATTCG TGGAATCAGT 1620

ATTTCCAAGT GTGACGAACG GTGTTGCTTC CTCTACGTGC TGCACACGGC CGAAGACTTC 1680

CAGTTGTATT TCCCTTCCCA GCACCATTGC CAGTGGTTTT GCAATCTCAT CCGTTCTTTC 1740

ATGGCCGAGA TGGGAGAGGA AGCTGACGGA TGCAGCTCTC CGGAGGAGCT GGAGTATGAC 1800

TACGAATACA CGGAAGTGGG CGACAAGGTG GTTCTCGGCA AAGGCACCTA CGGGGTGGTC 1860

TATGCTGGGA GGGACCTCAG CAATCAAGTG CGCATCGCCA TTAAGGAGAT CCCGGAGCGG 1920

GACAGCAGAT ACTCGCAGCC GTTGCACGAA GAGATCGCTC TCCATAAGCG TCTGAAGCAC 1980

AAGAACATTG TCCGCTACTT GGGCTCCGTC AGTCAAGATG GCTATCTCAA GATCTTTATG 2040

GAGGAGGTCC CTGGGGGGAG CCTCTCCTCT CTCCTGCGCT CCATGTGGGG CCCGCTGAAG 2100

GACAACGAAC CCACCATTGT TTACTACACC AAGCAGATCT TAGAGGGGCT GCGCTACTTG 2160

CACGACAACC AGATTGTCCA TAGGGATATC AAGGGAGACA ACGTCTTGAT CAACACGTAC 2220

AACGGAGTAT TAAAAATTTC TGACTTTGGC ACCTCCAAGA GATTGGCAGG CATCAGTCCC 2280

AGTGCAGAGA CTTTCACAGG CACCTTGCAA TACATGGCCC CAGAGGTCAT TGACCAGGGA 2340

CCCCGGGGCT ACGGCAAGCC GGCTGACATC TGGTCCTTGG GCTGCACCAT TATTGAGATG 2400

GCGACAGGCA AACCCCCGTT CTTTGAGCTC GGCAGCCCAC AGGCCGCCAT GTTCAAGGTG 2460

GGCATGTTCA AGATCCATCC TGAGGTGCCC AGCTCCATGT CGGATGAAGC CAAAGCCTTT 2520

ATCCTGAGTT GTTTTGAGGC TGATCCGGAC AAGCGGGCAA CGGCTGCCGC CTTGCTCCAG 2580

GAACCCTTTC TGAAGTCAAC CAGCAGGAAG AAAGCTCGGA GCCCCGTGAT GATGACAGTT 2640

CAGTTTGTAA CAAGCGATTT CTTCCACTTC TTTTGCATTG CGATGCCCTT ACCTTTAATT 2700

CTGCTCTATT TTTCACAAGT TTTACCTTAT AAGAGTGCCC TCCCTCCCTC CTTAGTATCT 2760

ATTTGTAAAT ACGAAACATA TAAAACTTAC AAATTACATC CGACTTACAA TTTCAAAACA 2820

AAGATTTGCA CATTCCTAAT AGGTACAAAG GCTCCCGAGG AAGCGGGCCA TTTTGACCTC 2880

AGCCTCTCCT CCTCTTCCCA CGAGGAGAGC GGGTGCTTGT TCTTGCTGAA GAAGGACAGC 2940

GAGCGGAGGG TCACCCTCTT CAAAGTCCTG ACCGAGGAGC TGCCCAGCAT CGCAGCCGCC 3000

CTGCACAAGG CCCAGGAAGA GAACCCGCTG TCCTTGGAGC TCGTCTCCCA GCTGGTCTCC 3060

TGCCTCAAGG GCTACATCCG CTCTCCCAGC CGCAAGCAGC TGGCCCAGGA CCTGCTCCGG 3120

CTCCAGGCCA GCTTGCAGGC TGAAGGACGG GGCCTTTGCC AACTACAAGT CCCACTCTTC 3180

ACTTTCCAAG ACACCGTGAA GCAGGCCCTG CGGAAGCTCC AGATCAAGCC TCACTGGGTG 3240

TTTGCTCTGG ACAACCTCAT GGGACAAGCC GTCCAGGCAG CGTTTACCAT CCTCTTGACA 3300

GAAGGAAGGG CGAAGAAGCT GGTCAACTTG ATGGGGTTTG TAGCTCACCA ATGTCAATTA 3360

GATGTTGGTG AACATGGGCC ATTCCAGCCC TCTCATGCCA AGATTACTTT AGAAGACCTC 3420

ACCCTCAAGG GCAGCATGGA CACGCCAAGT TCTGGCATTG GCACCACCAC CAACAGCTGG 3480

GTGGATTCCC AGCACGCGCT CAGAGGCCGC TTGCCCCTCA TGGCCCAGCT GCACCAGTTG 3540

CAGGCAGAGA CCCGGAGGCT GCAGTGGAAA CTGATAGAGA AGGAGCGTGA ATTCCAGAGA 3600

CTTCTGCAGG AGGCCCTGCA AGCGGTGAAG CAGGACGGCC ACGCTCTACA AAGTCCAAAG 3660

CCAACAGGGA TTAAGGAAAA GCCTATTACA CATCAAATTA GGAAAGAAGA GGAGGCGGCA 3720

GATCCCAGGC TCGCTGCGTG GTTAGAAAAA CAGGGAGTGG ACAAAGCTAC GATTGCAAAG 3780

CTCTCTGGCC ACGGCTTCAC CTTGCCGATC CTGTTGAATT GTGCGACAAT TGACGACCTC 3840

CGGTACACCT GCATCAGAGG AGGAATGGTG TGCCGCATCT GGAGAGCTCT CGCGAACCAT 3900

CGGCAAGCCC TTGGC 3915

Domain Profile

S: 4     revigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkHeni  63

         + v+gkG++g vya++d++++ ++a+Ke+   pe++s+  ++++l+eEi+l+k+lkH+ni

Q: 609   KVVLGKGTYGVVYAGRDLSNQVRIAIKEI---PERDSR--YSQPLHEEIALHKRLKHKNI  663

         789**************************...888775..9*******************

S: 64    vkyyGveveeeelkiflEyvegGslsslle.kygkle..esvikkytkqileglayLHek  120

         v+y+G+ +++++lkif+E v+gGslssll+ ++g+l+  e +i  ytkqilegl+yLH++

Q: 664   VRYLGSVSQDGYLKIFMEEVPGGSLSSLLRsMWGPLKdnEPTIVYYTKQILEGLRYLHDN  723

         ******************************9*****98899*******************

S: 121   kivHRDiKgaNillds.sgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikkk  179

         +ivHRDiKg+N+l+++ +gv+k+sDFG+skrla ++++   +e++tGtl+ymaPEvi+++

Q: 724   QIVHRDIKGDNVLINTyNGVLKISDFGTSKRLAGISPS---AETFTGTLQYMAPEVIDQG  780

         ****************9******************998...8******************

S: 180   ekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkdf  239

          +gyg+ aDiWslgc++iem+tgk+Pf el++++a+mfkvg+ k++Pe+p+++s+e+k+f

Q: 781   PRGYGKPADIWSLGCTIIEMATGKPPFFELGSPQAAMFKVGMFKIHPEVPSSMSDEAKAF  840

         ************************************************************

S: 240   lekcleldpkkrpsaeeLLkhefl  263

         + +c+e dp+kr++a+ LL+++fl

Q: 841   ILSCFEADPDKRATAAALLQEPFL  864

         **********************96

Domain Sequence
(FASTA)

KVVLGKGTYG VVYAGRDLSN QVRIAIKEIP ERDSRYSQPL HEEIALHKRL KHKNIVRYLG 60

SVSQDGYLKI FMEEVPGGSL SSLLRSMWGP LKDNEPTIVY YTKQILEGLR YLHDNQIVHR 120

DIKGDNVLIN TYNGVLKISD FGTSKRLAGI SPSAETFTGT LQYMAPEVID QGPRGYGKPA 180

DIWSLGCTII EMATGKPPFF ELGSPQAAMF KVGMFKIHPE VPSSMSDEAK AFILSCFEAD 240

PDKRATAAAL LQEPFL 256

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Myotis lucifugus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR025136	; DUF4071.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR013761	; SAM/pointed.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF13281	; DUF4071; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013