EKS-AIM-00136

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00136

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/CDC7	532.1	4.4E-160	58	573	516

Status

Unreviewed

Ensembl Protein

ENSAMEP00000000528

UniProt Accession

G1L0X6;

Protein Name

Protein Synonyms/Alias

Gene Name

CDC7

Gene Synonyms/Alias

CDC7;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000000492	ENSAMEP00000000528	ENSAMET00000000547

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

578

Protein Sequence
(FASTA)

MEASLGIQMD EPMAFSPQRD QVQADGSLKK NEQNFKLPGV KQDIEKLYEA VPQLGNLFKI 60

KDKIGEGTFS SVYLATAQLQ VGPEEKIALK HLIPTSHPIR IAAELQCLTV AGGQDNVMGV 120

KYCFRKNDHV VIAMPYLEHE SFLDILNSLS FQEVREYMFN LFKALKRIHQ FGIVHRDVKP 180

SNFLYNRRLK KYALVDFGLA QGTHDTKIEL LKFVQSEAQQ ESYSQNKSHV ITGNKISLSG 240

PAKPKESDQQ PTVKTSVKRP YTNAQSQIKQ GKDGKEGSVG LSVQRSVFGE RNFNIHSSIS 300

HESPAVKLMK QSKTVDVLSR KLATKKKAVS TKVMNSGVMR KTASSCPASL TCDCYATDKV 360

CSICLSSIIR RQQVAPRAGT PGFRAPEVLT KCPNQTTAID MWSAGVIFLS LLSGRYPFYK 420

ASDDLTALAQ IMTIRGSRET IQAAKTFGKS ILCSKEVPAQ DLRKLCEKLR GIDSNTPQLT 480

GDIQGPASHD PTFSEKTDHR AAHLKHTPQA QHSGSSLYEG DSNGCGGSLN TDATNSEGWN 540

EVPDEAYDLL DKLLDLNPAS RITAGEALLH PLFKDMSL 578

Nucleotide Sequence
(FASTA)

ATGGAGGCGT CTTTGGGGAT TCAGATGGAT GAACCAATGG CTTTTTCTCC CCAGCGTGAC 60

CAGGTTCAGG CGGATGGCTC GTTAAAAAAA AATGAGCAGA ATTTTAAACT ACCAGGTGTT 120

AAACAAGATA TTGAGAAGCT TTATGAAGCT GTACCACAGC TTGGTAATCT GTTTAAGATT 180

AAGGACAAAA TTGGAGAAGG CACTTTCAGC TCTGTTTATT TGGCCACAGC ACAGTTACAA 240

GTAGGACCTG AAGAGAAAAT TGCTCTAAAA CACTTAATTC CAACAAGTCA TCCTATAAGA 300

ATTGCAGCTG AACTTCAGTG CCTAACAGTG GCGGGGGGGC AAGACAATGT CATGGGAGTT 360

AAATACTGCT TTAGGAAAAA TGATCACGTG GTTATTGCTA TGCCGTATCT GGAGCATGAG 420

TCCTTTTTGG ACATTTTGAA TTCTCTTTCC TTTCAAGAAG TACGGGAATA TATGTTTAAT 480

CTGTTCAAAG CTTTGAAACG CATTCATCAG TTTGGTATTG TTCACCGTGA TGTTAAACCC 540

AGCAATTTTT TATATAACAG GCGCCTGAAA AAGTACGCAT TGGTAGACTT TGGTTTGGCA 600

CAAGGAACCC ATGATACGAA AATAGAGCTG CTCAAATTTG TCCAATCTGA AGCTCAGCAG 660

GAAAGTTATT CACAAAATAA ATCCCATGTA ATCACAGGAA ACAAGATTTC GTTGAGTGGC 720

CCAGCAAAAC CTAAGGAGTC GGATCAGCAG CCCACTGTGA AAACGTCTGT TAAAAGGCCC 780

TACACAAATG CACAGAGTCA GATTAAACAA GGAAAAGATG GAAAGGAGGG ATCTGTAGGC 840

CTTTCTGTCC AGCGCTCTGT TTTTGGAGAA AGAAATTTCA ATATACACAG CTCCATTTCA 900

CATGAGAGCC CTGCAGTGAA ACTTATGAAA CAGTCAAAGA CTGTGGATGT ACTGTCTAGA 960

AAGTTAGCAA CAAAAAAGAA GGCTGTTTCT ACAAAAGTTA TGAATAGTGG TGTGATGAGG 1020

AAAACTGCCA GTTCTTGCCC AGCTAGCCTG ACCTGTGACT GTTACGCAAC AGATAAAGTT 1080

TGCAGTATTT GCCTTTCAAG CATCATAAGG CGGCAACAGG TTGCCCCTAG GGCAGGTACA 1140

CCGGGATTCA GAGCACCAGA GGTTTTGACA AAGTGCCCCA ATCAAACTAC AGCAATTGAC 1200

ATGTGGTCTG CAGGTGTCAT ATTCCTTTCT TTGCTTAGTG GGCGATATCC ATTTTATAAA 1260

GCAAGTGATG ATTTAACTGC TTTGGCTCAA ATTATGACAA TTCGTGGATC CAGGGAAACT 1320

ATCCAAGCTG CTAAAACTTT TGGCAAATCA ATATTGTGTA GCAAAGAAGT CCCAGCACAA 1380

GACTTGAGAA AACTCTGTGA GAAGCTCAGA GGTATTGATT CTAACACTCC CCAGTTAACA 1440

GGTGATATAC AAGGGCCTGC TTCTCATGAC CCAACTTTTT CAGAGAAGAC TGACCATAGA 1500

GCTGCTCACC TCAAACACAC ACCTCAAGCA CAGCACTCGG GGAGTTCATT GTATGAAGGG 1560

GACAGTAATG GCTGTGGGGG TAGTTTGAAT ACGGATGCTA CCAATTCAGA AGGCTGGAAT 1620

GAGGTACCTG ACGAAGCTTA TGACCTGCTT GATAAACTTC TAGATCTAAA TCCAGCTTCA 1680

AGAATAACAG CAGGAGAAGC TTTGTTGCAT CCTCTTTTTA AAGATATGAG CTTGTGA 1737

Domain Profile

S: 1     fkikdkiGeGtfssvylataqleegleekialkhliptshPeriaaeLelltvlgGqenv  60

         fkikdkiGeGtfssvylataql++g+eekialkhliptshP+riaaeL++ltv+gGq+nv

Q: 58    FKIKDKIGEGTFSSVYLATAQLQVGPEEKIALKHLIPTSHPIRIAAELQCLTVAGGQDNV  117

         9***********************************************************

S: 61    vglkecfrkndsvvivlpylehesfldllrslsfqevreYlrnLlvalkrvhkfgivhrD  120

         +g+k+cfrknd+vvi++pylehesfld+l+slsfqevreY++nL++alkr+h+fgivhrD

Q: 118   MGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMFNLFKALKRIHQFGIVHRD  177

         ************************************************************

S: 121   vkpsnfLynrrlkkfaLvDfGLaq..............seaqkeecsrn..........l  156

         vkpsnfLynrrlkk+aLvDfGLaq              seaq+e+ s+n

Q: 178   VKPSNFLYNRRLKKYALVDFGLAQgthdtkiellkfvqSEAQQESYSQNkshvitgnkiS  237

         *************************************************77666666664

S: 157   lsaavekevd..................................................  166

         ls++

Q: 238   LSGP-----Akpkesdqqptvktsvkrpytnaqsqikqgkdgkegsvglsvqrsvfgern  292

         4444.....04444469999999*************************************

S: 167   ..........................................................tc  168

tc

Q: 293   fnihssishespavklmkqsktvdvlsrklatkkkavstkvmnsgvmrktasscpaslTC  352

         ************************************************************

S: 169   dcygtdkvcsvcls...rrqqvanraGtpGfraPevLlkipdqttaiDiwsaGvilLsll  225

         dcy+tdkvcs+cls   rrqqva+raGtpGfraPevL+k+p+qttaiD+wsaGvi+Lsll

Q: 353   DCYATDKVCSICLSsiiRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSAGVIFLSLL  412

         *************95666******************************************

S: 226   sgryPffkasddlealaeivtilGsreiikaakafgksvllskevp..............  271

         sgryPf+kasddl+ala+i+ti+Gsre+i+aak+fgks+l+skevp

Q: 413   SGRYPFYKASDDLTALAQIMTIRGSRETIQAAKTFGKSILCSKEVPaqdlrklceklrgi  472

         ************************************************************

S: 272   ............................................................  271

Q: 473   dsntpqltgdiqgpashdptfsektdhraahlkhtpqaqhsgsslyegdsngcggslntd  532

         ************************************999999999999666666665554

S: 272   .dsdsye.......PdeaydlldkllelnPakritaeealkhpff  308

               +       Pdeaydlldkll+lnPa+rita eal+hp f

Q: 533   aT----NsegwnevPDEAYDLLDKLLDLNPASRITAGEALLHPLF  573

         41....15566789*****************************87

Domain Sequence
(FASTA)

FKIKDKIGEG TFSSVYLATA QLQVGPEEKI ALKHLIPTSH PIRIAAELQC LTVAGGQDNV 60

MGVKYCFRKN DHVVIAMPYL EHESFLDILN SLSFQEVREY MFNLFKALKR IHQFGIVHRD 120

VKPSNFLYNR RLKKYALVDF GLAQGTHDTK IELLKFVQSE AQQESYSQNK SHVITGNKIS 180

LSGPAKPKES DQQPTVKTSV KRPYTNAQSQ IKQGKDGKEG SVGLSVQRSV FGERNFNIHS 240

SISHESPAVK LMKQSKTVDV LSRKLATKKK AVSTKVMNSG VMRKTASSCP ASLTCDCYAT 300

DKVCSICLSS IIRRQQVAPR AGTPGFRAPE VLTKCPNQTT AIDMWSAGVI FLSLLSGRYP 360

FYKASDDLTA LAQIMTIRGS RETIQAAKTF GKSILCSKEV PAQDLRKLCE KLRGIDSNTP 420

QLTGDIQGPA SHDPTFSEKT DHRAAHLKHT PQAQHSGSSL YEGDSNGCGG SLNTDATNSE 480

GWNEVPDEAY DLLDKLLDLN PASRITAGEA LLHPLF 516

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0008284	; P:positive regulation of cell proliferation
GO:0033261	; P:regulation of S phase

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 2.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013