EPS-AIM-00089

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-AIM-00089

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP2A	419.7	1.5E-126	50	242	193

Status

Unreviewed

Ensembl Protein

ENSAMEP00000001711

UniProt Accession

G1L4A1;

Protein Name

Serine/threonine-protein phosphatase

Protein Synonyms/Alias

Gene Name

PPP2CB

Gene Synonyms/Alias

PPP2CB;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000001615	ENSAMEP00000001711	ENSAMET00000001777

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

308

Protein Sequence
(FASTA)

DDKAFTKELD QWVEQLNECK QLNENQVRTL CEKAKEILTK ESNVQEVRCP VTVCGDVHGQ 60

FHDLMELFRI GGKSPDTNYL FMGDYVDRGY YSVETVTLLV ALKVRYPERI TILRGNHESR 120

QITQVYGFYD ECLRKYGNAN VWKYFTDLFD YLPLTALVDG QIFCLHGGLS PSIDTLDHIR 180

ALDRLQEVPH EGPMCDLLWS DPDDRGGWGI SPRGAGYTFG QDISETFNHA NGLTLVSRAH 240

QLVMEGYNWC HDRNVVTIFS APNYCYRCGN QAAIMELDDT LKYSFLQFDP APRRGEPHVT 300

RRTPDYFL 308

Nucleotide Sequence
(FASTA)

GACGACAAGG CGTTCACCAA GGAGCTGGAC CAGTGGGTCG AGCAGCTGAA CGAGTGTAAA 60

CAGCTTAACG AGAACCAAGT GCGGACTCTG TGCGAAAAGG CTAAGGAAAT ATTAACAAAA 120

GAATCAAATG TGCAAGAGGT TCGTTGTCCT GTTACCGTGT GTGGAGATGT GCATGGTCAA 180

TTCCATGATC TTATGGAACT CTTTAGAATT GGTGGAAAAT CACCAGATAC AAACTATCTG 240

TTCATGGGCG ACTATGTAGA CAGAGGCTAT TACTCAGTGG AGACTGTGAC TCTTCTTGTG 300

GCATTAAAGG TGCGTTATCC AGAACGCATT ACTATATTGA GAGGAAACCA CGAAAGCCGA 360

CAAATCACCC AAGTATATGG CTTTTATGAT GAATGTCTAC GAAAGTATGG AAATGCCAAT 420

GTTTGGAAAT ATTTTACAGA TCTATTTGAT TATCTTCCAC TTACAGCTTT AGTAGATGGA 480

CAGATATTCT GCCTCCACGG TGGCCTGTCT CCATCCATAG ATACACTGGA TCATATAAGA 540

GCTTTGGATC GTTTACAAGA AGTTCCACAT GAGGGCCCAA TGTGTGATCT GTTGTGGTCA 600

GATCCGGATG ATCGTGGTGG GTGGGGTATC TCACCACGTG GTGCTGGCTA CACATTTGGA 660

CAGGACATTT CTGAAACGTT TAACCATGCC AATGGTCTCA CACTGGTTTC TCGAGCTCAT 720

CAACTTGTAA TGGAGGGGTA CAATTGGTGT CATGATCGGA ATGTGGTTAC CATTTTCAGT 780

GCACCCAATT ACTGCTACCG TTGTGGGAAC CAGGCTGCTA TCATGGAATT AGATGACACT 840

TTAAAATACT CCTTCCTTCA GTTTGACCCA GCACCTCGTC GTGGAGAGCC TCATGTTACC 900

CGGCGCACCC CAGACTACTT CCTG 924

Domain Profile

S: 1     pvtvcgdvhgqfhdllelfriggkspdtnylflgdyvdrgyysvetvtllvalkvryrer  60

         pvtvcgdvhgqfhdl+elfriggkspdtnylf+gdyvdrgyysvetvtllvalkvry+er

Q: 50    PVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPER  109

         9***********************************************************

S: 61    itilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdgkifclhggl  120

         itilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdg+ifclhggl

Q: 110   ITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGL  169

         ************************************************************

S: 121   spsidtldeiraldrlqevphegplcdllwsdpddregwgisprgagytfgqdiseqfnh  180

         spsidtld+iraldrlqevphegp+cdllwsdpddr+gwgisprgagytfgqdise+fnh

Q: 170   SPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNH  229

         ************************************************************

S: 181   angleliarahql  193

         angl+l++rahql

Q: 230   ANGLTLVSRAHQL  242

         ************8

Domain Sequence
(FASTA)

PVTVCGDVHG QFHDLMELFR IGGKSPDTNY LFMGDYVDRG YYSVETVTLL VALKVRYPER 60

ITILRGNHES RQITQVYGFY DECLRKYGNA NVWKYFTDLF DYLPLTALVD GQIFCLHGGL 120

SPSIDTLDHI RALDRLQEVP HEGPMCDLLW SDPDDRGGWG ISPRGAGYTF GQDISETFNH 180

ANGLTLVSRA HQL 193

Keyword

Complete proteome; Hydrolase; Iron; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0000159	; C:protein phosphatase type 2A complex
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0043066	; P:negative regulation of apoptotic process
GO:0043161	; P:proteasomal ubiquitin-dependent protein catabolic process
GO:0010468	; P:regulation of gene expression
GO:0046677	; P:response to antibiotic
GO:0042542	; P:response to hydrogen peroxide

KEGG

InterPros

IPR004843	; Metallo_PEstase_dom.
IPR006186	; Ser/Thr-sp_prot-phosphatase.

Pfam

PF00149

; Metallophos; 1.

SMARTs

SM00156

; PP2Ac; 1.

Prosites

PS00125

; SER_THR_PHOSPHATASE; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013