EKS-AIM-00054

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00054

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	392.0	1.5E-117	195	476	282

Status

Unreviewed

Ensembl Protein

ENSAMEP00000002090

UniProt Accession

G1L5C9;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK17

Gene Synonyms/Alias

CDK17;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000001927	ENSAMEP00000002090	ENSAMET00000002178

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

526

Protein Sequence
(FASTA)

VDRMKKFKRR LSLTLRGSQT IDESLSELAE QMTIEENSSK DNEPIVKNGR PPTSHSMHSF 60

LHQYTGSFKK PPLRRPHSVI GGSLGSFMAM PRNGSRLDIV HENLKMGSDG ESDQASGTSS 120

DEVQSPTGVC LRNRIHRRIS MEDLNKRLSL PADIRIPDGY LEKLQINSPP FDQPMSRRSR 180

RASLSEIGFG KMETYIKLEK LGEGTYATVY KGRSKLTENL VALKEIRLEH EEGAPCTAIR 240

EVSLLKDLKH ANIVTLHDIV HTDKSLTLVF EYLDKDLKQY MDDCGNIMSM HNVKLFLYQI 300

LRGLAYCHRR KVLHRDLKPQ NLLINEKGEL KLADFGLARA KSVPTKTYSN EVVTLWYRPP 360

DVLLGSSEYS TQIDMWGVGC IFFEMASGRP LFPGSTVEDE LHLIFRLLGT PSQETWPGVS 420

SNDEFKNYNF PKYKPQPLIN HAPRLDSEGI ELITKFLQYE SKKRVSAEEA MKHVYFRSLG 480

PRIHTLPESV SIFSLKEIQL QKDPGFRNSS YPETGHGKNR RQSMLF 526

Nucleotide Sequence
(FASTA)

GTTGATAGGA TGAAAAAATT TAAGAGAAGG CTATCCCTCA CTCTTCGGGG AAGCCAGACT 60

ATTGATGAAT CATTGTCTGA ATTGGCGGAA CAAATGACTA TTGAAGAAAA CAGCAGCAAG 120

GATAATGAGC CTATTGTGAA GAATGGCAGG CCTCCAACCT CTCACAGTAT GCATTCCTTC 180

CTCCACCAGT ACACAGGGTC CTTCAAGAAG CCCCCATTGC GGAGACCACA TAGTGTTATT 240

GGAGGAAGCC TTGGATCCTT CATGGCAATG CCCAGAAATG GAAGCAGATT AGATATTGTT 300

CATGAAAATC TAAAAATGGG ATCAGATGGT GAGAGTGACC AAGCTTCTGG GACATCATCT 360

GATGAAGTAC AGTCACCTAC AGGCGTTTGT CTTAGGAATC GTATACATAG ACGGATCTCA 420

ATGGAGGATT TAAATAAGCG GTTATCACTG CCAGCAGATA TCAGAATACC TGATGGATAT 480

CTTGAAAAAT TGCAGATAAA CAGTCCACCG TTTGATCAAC CAATGAGCCG AAGGTCTCGT 540

AGAGCTTCAT TATCAGAAAT TGGGTTTGGA AAAATGGAAA CCTATATCAA ATTGGAAAAG 600

CTTGGAGAGG GTACATATGC GACAGTATAT AAAGGAAGAA GTAAATTGAC AGAGAATTTG 660

GTGGCATTAA AAGAGATCCG GTTGGAACAT GAAGAAGGTG CACCCTGCAC AGCTATAAGA 720

GAAGTTTCAC TATTAAAGGA TCTAAAACAT GCAAATATAG TGACTTTACA TGACATTGTT 780

CATACAGATA AATCTTTGAC TCTGGTCTTT GAGTATCTGG ATAAAGACCT AAAACAGTAC 840

ATGGATGACT GTGGAAACAT CATGAGTATG CACAATGTAA AGCTGTTTTT ATACCAAATT 900

CTACGTGGTT TGGCATATTG CCACAGAAGA AAGGTATTGC ACCGAGACTT GAAACCACAG 960

AACCTACTCA TTAATGAAAA AGGAGAATTA AAGCTAGCAG ATTTTGGGCT AGCCAGAGCC 1020

AAGTCAGTTC CCACAAAGAC CTACTCCAAT GAAGTCGTCA CACTGTGGTA CCGGCCACCT 1080

GATGTGCTTC TCGGTTCCTC AGAGTACTCA ACTCAGATTG ACATGTGGGG TGTTGGTTGC 1140

ATTTTCTTTG AAATGGCTTC TGGAAGACCT CTGTTTCCAG GATCAACTGT GGAAGATGAG 1200

CTGCACTTAA TTTTCCGACT GCTAGGAACA CCATCTCAGG AAACTTGGCC AGGTGTTTCT 1260

TCAAATGATG AGTTCAAGAA CTACAACTTT CCAAAATACA AACCACAGCC TCTCATTAAC 1320

CATGCACCCA GATTAGACTC TGAGGGAATC GAGTTAATAA CAAAGTTTCT TCAGTATGAA 1380

TCTAAGAAAA GGGTTTCAGC AGAAGAGGCC ATGAAGCATG TATACTTTCG AAGTCTGGGA 1440

CCAAGAATAC ATACTTTACC TGAAAGTGTA TCAATATTCA GTTTGAAAGA GATTCAGTTG 1500

CAAAAGGACC CGGGTTTTCG AAATTCTTCT TATCCAGAGA CAGGACACGG GAAGAACAGA 1560

AGACAGAGCA TGCTCTTTTA A 1581

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y klek+geGty++vyk+++k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 195   YIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  253

         7799********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++v+ ++k+l+Lvfe+l++dLk++++++ +  +s+++vk +l+q+l+glay+H++k

Q: 254   VTLHDIVH-TDKSLTLVFEYLDKDLKQYMDDCGN-IMSMHNVKLFLYQILRGLAYCHRRK  311

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg++eYst

Q: 312   VLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYST  371

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e+++ +plf+g++  d+l+ if+llgtps+++wp+vs+  e+k ++fp

Q: 372   QIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKnYNFP  431

         *******************************************************99***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k+k++ l ++ ++l++++++l++k+l+++ kkR+sa+ea++h yf

Q: 432   KYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYF  476

         ********************************************8

Domain Sequence
(FASTA)

YIKLEKLGEG TYATVYKGRS KLTENLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIVHTDK SLTLVFEYLD KDLKQYMDDC GNIMSMHNVK LFLYQILRGL AYCHRRKVLH 120

RDLKPQNLLI NEKGELKLAD FGLARAKSVP TKTYSNEVVT LWYRPPDVLL GSSEYSTQID 180

MWGVGCIFFE MASGRPLFPG STVEDELHLI FRLLGTPSQE TWPGVSSNDE FKNYNFPKYK 240

PQPLINHAPR LDSEGIELIT KFLQYESKKR VSAEEAMKHV YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013