EKS-AIM-00230

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00230

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	321.7	3.1E-96	2	241	240

Status

Unreviewed

Ensembl Protein

ENSAMEP00000002076

UniProt Accession

G1L5B5;

Protein Name

Protein Synonyms/Alias

Gene Name

BRSK2

Gene Synonyms/Alias

BRSK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000001939	ENSAMEP00000002076	ENSAMET00000002160

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

724

Protein Sequence
(FASTA)

TGLVKLGIHC VTCQKVAIKI VNREKLSESV LMKVEREIAI LKLIEHPHVL KLHDVYENKK 60

YLYLVLEHVS GGELFDYLVK KGRLTPKEAR KFFRQIISAL DFCHSHSICH RDLKPENLLL 120

DEKNNIRIAD FGMASLQVGD SLLETSCGSP HYACPEVIRG EKYDGRKADV WSCGVILFAL 180

LVGALPFDDD NLRQLLEKVK RGVFHMPHFI PPDCQSLLRG MIEVDAARRL TLEHIQKHIW 240

YIGGKNEPEP EQPIPRKVQI RSLPSLEDID PDVLDSMHSL GCFRDRNKLL QDLLSEEENQ 300

EKMIYFLLLD RKERYPSHED EDLPPRNEID PPRKRVDSPM LNRHGKRRPE RKSMEVLSVT 360

DGGSPVPARR AIEMAQHGQR SRSISGASSG LSTSPLSSPR PEACRSASRP GHVLPPQAAS 420

RPNPKTQTLP SKAKLTDKPL QGTKSNPLPA GTQVTPHPSP RGSPLPTPKG TPVHTPKESP 480

AGTPNPTPPS SPSVGGVPWR TRLNSIKNSF LGSPRFHRRK LQVPTPEEMS NLTPESSPEL 540

AKKSWFGNFI NLEKEEQIFV VIKDKPLSSI KADIVHAFLS IPSLSHSVIS QTSFRAEYKA 600

TGGPAVFQKP VKFQVDITYT EGGAAQKENG IYSVTFTLLS GPSRRFKRVV ETIQTQLLST 660

HDQPSAQHLS GEGCGPFDMP TSLPPRGQGP PRRRGPAHVC TPREVGPAHH TERRLLSTIE 720

PPPP 724

Nucleotide Sequence
(FASTA)

ACAGGCCTTG TGAAGCTGGG AATTCACTGT GTCACGTGCC AGAAAGTGGC CATCAAAATC 60

GTCAACCGGG AGAAGCTCAG CGAGTCTGTG CTGATGAAGG TGGAGCGGGA GATCGCCATC 120

CTGAAGCTCA TCGAACACCC TCACGTCCTG AAGCTACACG ACGTTTATGA AAACAAAAAA 180

TATTTATACC TGGTGCTAGA ACACGTGTCT GGTGGGGAGC TCTTCGACTA CCTTGTCAAG 240

AAGGGGAGGC TGACCCCCAA AGAGGCCCGG AAGTTCTTCC GGCAGATCAT CTCCGCGCTG 300

GACTTCTGCC ACAGCCACTC TATATGCCAC AGGGACCTGA AGCCGGAAAA CCTGCTCCTG 360

GACGAGAAAA ACAACATCCG GATCGCCGAC TTCGGCATGG CCTCGCTGCA GGTTGGCGAC 420

AGCCTGCTGG AGACCAGCTG CGGATCCCCC CACTACGCCT GCCCCGAGGT GATCCGGGGG 480

GAGAAGTATG ACGGCCGCAA GGCAGACGTG TGGAGCTGCG GCGTGATCCT GTTCGCCCTG 540

TTGGTGGGGG CGCTGCCCTT CGACGACGAC AACCTGAGGC AGCTGCTGGA GAAGGTGAAG 600

CGAGGCGTGT TTCACATGCC GCACTTCATC CCGCCCGACT GCCAGAGCCT GCTGCGCGGC 660

ATGATCGAGG TGGACGCCGC CCGGCGCCTC ACGCTAGAGC ACATTCAGAA ACACATATGG 720

TATATAGGGG GCAAGAACGA GCCAGAGCCA GAGCAGCCCA TCCCCCGCAA GGTGCAGATC 780

CGTTCGCTGC CCAGCCTGGA GGACATTGAC CCCGACGTGC TGGACAGCAT GCACTCGCTG 840

GGCTGCTTCC GGGACCGCAA CAAGCTGCTG CAGGACCTGC TGTCCGAGGA GGAAAACCAG 900

GAGAAGATGA TTTATTTCCT CCTCCTGGAC CGGAAAGAAA GGTACCCGAG CCATGAGGAT 960

GAGGACCTGC CCCCCAGAAA TGAAATAGAC CCTCCCCGGA AGCGTGTGGA CTCCCCAATG 1020

CTGAACCGGC ACGGCAAACG GCGGCCTGAA CGCAAGTCCA TGGAGGTGCT CAGCGTGACA 1080

GATGGTGGCT CCCCAGTGCC CGCGCGGCGG GCCATCGAGA TGGCCCAGCA TGGCCAGAGG 1140

TCCAGGTCCA TCAGCGGCGC CTCCTCGGGC CTGTCCACCA GCCCGCTGAG CAGCCCCCGG 1200

CCTGAAGCTT GTCGGAGCGC CTCTCGGCCC GGACACGTCC TCCCTCCACA GGCCGCCTCG 1260

CGGCCCAACC CCAAGACCCA GACCTTGCCG AGCAAGGCCA AGCTGACCGA CAAGCCACTG 1320

CAGGGCACCA AGTCCAACCC ACTCCCGGCT GGCACCCAGG TGACCCCTCA CCCCTCTCCA 1380

AGGGGTAGTC CCCTCCCCAC CCCTAAGGGG ACGCCCGTGC ACACGCCCAA GGAGAGCCCG 1440

GCGGGCACGC CCAACCCCAC ACCACCGTCC AGCCCCAGCG TCGGAGGGGT GCCCTGGAGG 1500

ACGCGGCTCA ACTCCATCAA GAACAGTTTC CTGGGGTCAC CCCGCTTCCA CCGCCGGAAA 1560

CTGCAAGTTC CGACACCCGA GGAGATGTCC AACCTGACCC CGGAGTCATC TCCAGAGCTC 1620

GCCAAGAAGT CCTGGTTTGG GAACTTCATC AACCTGGAGA AGGAGGAGCA GATCTTCGTG 1680

GTCATCAAGG ACAAGCCCCT GAGCTCCATC AAAGCGGACA TTGTCCACGC CTTCCTGTCG 1740

ATCCCCAGCC TCAGCCACAG CGTCATCTCC CAGACGAGCT TCCGGGCCGA GTATAAGGCC 1800

ACGGGGGGCC CGGCTGTGTT CCAGAAGCCA GTCAAGTTCC AGGTGGACAT CACCTACACG 1860

GAGGGCGGGG CGGCGCAGAA GGAGAACGGC ATCTATTCCG TCACGTTCAC GCTCCTGTCA 1920

GGCCCCAGCC GCCGCTTCAA GAGGGTCGTG GAGACCATTC AGACCCAGCT ACTGAGCACA 1980

CATGACCAGC CCTCTGCCCA GCATTTGTCA GGTGAGGGGT GTGGCCCCTT CGACATGCCC 2040

ACCTCCCTGC CCCCCCGGGG GCAGGGCCCT CCCCGGCGCA GGGGGCCGGC CCATGTCTGC 2100

ACACCCAGGG AGGTAGGCCC AGCACACCAC ACTGAAAGGC GCCTCTTGTC CACTATAGAA 2160

CCCCCCCCGC CA 2172

Domain Profile

S: 13    gkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpniikllevietkkk  72

         g Vkl +h  t +kva+Ki++++klse+ l k++rEi+ilk ++hp+++kl++v+e+kk+

Q: 2     GLVKLGIHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKY  61

         78**********************************************************

S: 73    lylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgivHrDlKpeNllld  132

         lylvle++sggeLfdy+++kgrl+ keark+f+q++sa++++hs++i+HrDlKpeNllld

Q: 62    LYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLD  121

         ************************************************************

S: 133   kkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvDvWslGvvLyalv  192

         +k+ni+iaDFG+a+l   ++llet+cGsp+Ya+Pe+++g+kY+g+k+DvWs+Gv+L+al+

Q: 122   EKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL  181

         ************************************************************

S: 193   tgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpekRatieeilkhewl  252

         +g+lPfd++nl++llek+++g +++p+ + ++++sLlr +++vd+++R+t+e+i+kh w+

Q: 182   VGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY  241

         **********************************************************95

Domain Sequence
(FASTA)

GLVKLGIHCV TCQKVAIKIV NREKLSESVL MKVEREIAIL KLIEHPHVLK LHDVYENKKY 60

LYLVLEHVSG GELFDYLVKK GRLTPKEARK FFRQIISALD FCHSHSICHR DLKPENLLLD 120

EKNNIRIADF GMASLQVGDS LLETSCGSPH YACPEVIRGE KYDGRKADVW SCGVILFALL 180

VGALPFDDDN LRQLLEKVKR GVFHMPHFIP PDCQSLLRGM IEVDAARRLT LEHIQKHIWY 240

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0050321	; F:tau-protein kinase activity
GO:0007409	; P:axonogenesis
GO:0030010	; P:establishment of cell polarity
GO:0018105	; P:peptidyl-serine phosphorylation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013