EPS-AIM-00032

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-AIM-00032

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	190.2	5.8E-56	779	1025	247

Status

Unreviewed

Ensembl Protein

ENSAMEP00000002551

UniProt Accession

G1L6N6;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000002396	ENSAMEP00000002551	ENSAMET00000002662

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

1317

Protein Sequence
(FASTA)

MKRNGSRNCL NRRSRFGSRE RDWLREDVRR GCVYLYGADT TTAATTASAS ASSDLHLVLC 60

TVETPASEIC AGEGRESLYL QLHGDLVSRR LEPTERPLQI VYDYLSRLGF DDPVRIQEEA 120

ADPDLGCMLR FYGEKPCQMD HLDRILLSGI YNVRKGKTQL HKWAERLVVL CGTCLIVSSV 180

KDCHTGKMHI LPLVGGKVEE VKRRQHSLAF SSAGAQAQTY HVSFETLAEC QRWQRQASKV 240

VSQRISTVDL SCYSLEEVPE HLFYSQDITY LNLRHNFMQL ERPGGLDTLY RFSQLKGLNL 300

SHNKLGLFPV MLCEISTLTE LNLSCNGFHD VPSQIGSLLN LQTLCLDGNF LMTLPEELGD 360

LQQLSSLGIS FNNFSQIPEV YEKLTMIDKV VMAGNRLEVL NLGVLNRMSH IKHVDLRMNH 420

LKTVVTENLE GNKYITHMDL RDNQLADLDL SSLCSLEQLH CERNQLRELT LSGFSLRTLY 480

ASSNRLTAVN VYPVPSQLTS LELSRNLLEC VPDWACEAKK MEILDVSYNL LTEVPMRILS 540

SLSLRKLTVG HNQVQSLPVL VEHIPLEALD IQHNLLTRLP DTLFSKALNL RYLNASANSL 600

ESLPSAGAGE ESLSALQLLY LTNNLLTDQC VPVLVGHPHL RILHLANNQL QTFPASKLNK 660

LEQLEELNLS GNKLKTIPTT IANCKRLHTL VAHSNNISIF PEILQLPQIQ FVDLSCNDLT 720

EILIPEALPA SLQDLDLTGN TNLVLEHKTL DTFSHISTLK IDQKPLPTTD ATVTSTFWSH 780

GLAEMAGQRN KLCVSALAVD NFAEGVGAVY GMFDGDRNEE LPRLLQCTMA DVLLEEVQQS 840

TNDTVFMANT FLVSHRKLGM AGQKLGSSAL LCYIRPDTAD PTSSFSLTVA NVGTCQAVLC 900

RSGKAVPLSK VFSLEQDPEE AQRVKDQKAI ITEDNKVNGV TCCTRMLGCT YLYPWILPKP 960

HISATPLTLQ DELLILGNKA LWEHLSYTEA VNAVRHVQDP LAAAKKLCTV AQSYGCQDNV 1020

GAMVVYLNIG EEGCTCDMNG LTLPGPVGFA STSIIKDPPK PTTPSSSSGI ASEFGSEMST 1080

SEVSSEVGST ASDDHNTVGL DAGLLPRPER RCSLHPTPTS GVFQRQPSCA TFSSNQSDNG 1140

LDSDDDQPVE GVITNGSKVE VEVDIHCCRG RGLEHSPTLI ENSPTRCPEE RARGSFFGIR 1200

RQNSVNSGIL LPVSKDRMEL QKSPSTSCLY GKKLSNGSIV PLEDSLNLIE VATEAPKKKT 1260

GYFAAPTQLE PEDQFVVPRD LEEEVKEQMK QHQESRPEPE PREEDRTELP EEFDTAL 1317

Nucleotide Sequence
(FASTA)

ATGAAACGCA ATGGGAGCAG GAATTGTTTG AATCGGCGAA GTAGGTTTGG TTCTCGAGAG 60

AGAGACTGGC TGAGAGAAGA TGTCAGGAGA GGTTGTGTTT ACCTGTATGG AGCAGACACG 120

ACCACTGCCG CCACAACCGC CTCTGCCTCC GCCTCCTCTG ACTTACATCT TGTCCTGTGC 180

ACTGTGGAGA CGCCAGCGTC AGAAATCTGT GCTGGAGAGG GAAGGGAAAG TCTGTATTTA 240

CAGCTTCATG GGGACCTGGT CAGCAGGAGA CTGGAACCTA CTGAACGACC TCTTCAGATT 300

GTTTATGATT ACTTATCCAG GCTGGGATTT GATGACCCTG TGCGTATACA GGAGGAGGCA 360

GCAGATCCTG ACCTCGGCTG CATGCTTCGA TTTTACGGTG AAAAACCATG CCAGATGGAT 420

CATCTGGATC GAATCCTCCT GTCTGGCATC TATAATGTAC GCAAGGGAAA GACCCAGCTG 480

CATAAGTGGG CTGAACGCCT AGTTGTTCTC TGTGGCACCT GCCTCATTGT TTCCTCAGTG 540

AAGGATTGTC ATACTGGAAA GATGCACATT TTGCCTCTGG TTGGGGGAAA GGTGGAAGAA 600

GTGAAGCGAC GGCAGCATTC CCTTGCGTTC AGCTCAGCTG GAGCCCAAGC TCAGACCTAT 660

CATGTCAGCT TTGAGACGTT GGCCGAGTGC CAGAGATGGC AGCGACAAGC ATCCAAGGTG 720

GTGTCCCAGC GAATCAGCAC TGTTGACCTC TCATGTTACA GCCTTGAGGA GGTCCCTGAG 780

CATCTCTTCT ACAGTCAAGA TATCACCTAC CTCAATTTGC GACACAACTT CATGCAGCTG 840

GAAAGACCAG GGGGCCTTGA CACTCTCTAC AGATTTTCTC AGTTGAAGGG CCTGAACTTG 900

TCCCATAATA AACTTGGGTT GTTTCCTGTA ATGTTATGTG AGATTTCTAC CCTGACTGAG 960

CTCAACCTCT CCTGTAACGG ATTTCATGAC GTGCCAAGTC AGATTGGCAG TCTACTAAAT 1020

CTTCAAACCC TCTGTCTTGA TGGCAACTTT CTGATGACTT TACCAGAAGA ATTGGGAGAT 1080

CTGCAACAGC TTTCTTCCCT GGGAATTTCC TTTAACAATT TTAGTCAAAT TCCTGAGGTT 1140

TATGAGAAAC TCACTATGAT AGATAAAGTG GTTATGGCAG GAAATCGCCT GGAAGTCCTC 1200

AACCTTGGGG TGCTGAACAG GATGAGCCAT ATCAAACATG TGGATTTAAG GATGAATCAT 1260

TTGAAAACCG TGGTTACTGA GAATCTGGAG GGAAATAAAT ACATCACCCA CATGGATTTG 1320

CGGGACAATC AACTGGCTGA CTTAGATCTT AGCTCCTTAT GTAGCTTGGA ACAGCTGCAC 1380

TGTGAACGGA ACCAGCTGAG AGAGCTGACA CTCAGTGGCT TCTCCCTTCG AACTCTCTAT 1440

GCCAGTTCCA ACAGGCTGAC AGCGGTGAAT GTCTATCCAG TACCCAGTCA ACTCACTTCT 1500

CTAGAGCTTT CACGAAACCT GCTAGAGTGT GTCCCTGACT GGGCCTGTGA AGCAAAGAAG 1560

ATGGAAATAT TAGATGTGAG CTATAATCTT CTGACAGAGG TTCCCATGAG AATCCTTAGT 1620

AGCTTGAGTC TCAGAAAGCT GACGGTGGGG CACAACCAGG TGCAGAGCCT GCCGGTGCTG 1680

GTGGAGCACA TCCCCCTGGA GGCACTGGAT ATTCAGCATA ACCTGCTCAC CAGGCTGCCA 1740

GATACGCTCT TCTCCAAGGC CTTAAATCTC AGATACTTGA ATGCATCTGC AAACAGTCTG 1800

GAATCTTTGC CATCTGCTGG GGCTGGAGAG GAGAGTCTGA GTGCTCTGCA GCTGCTCTAT 1860

CTGACCAACA ACCTCCTGAC AGACCAGTGT GTGCCTGTTC TGGTGGGCCA CCCGCACCTG 1920

CGGATCTTGC ATCTTGCGAA TAACCAGCTA CAGACCTTTC CTGCAAGCAA ATTAAATAAA 1980

TTGGAGCAAC TGGAGGAACT GAACCTAAGT GGCAACAAGC TTAAAACCAT TCCCACGACC 2040

ATAGCCAACT GCAAAAGGCT TCATACCCTT GTGGCTCACT CCAACAACAT CAGCATTTTC 2100

CCAGAAATAC TGCAGTTGCC TCAGATCCAG TTTGTAGACC TAAGTTGCAA TGACTTGACA 2160

GAAATCCTGA TTCCAGAGGC TCTGCCTGCC TCTTTACAAG ACCTTGACCT GACGGGAAAT 2220

ACGAATCTGG TTCTGGAACA CAAGACGCTG GACACGTTTA GCCATATCTC CACCTTGAAA 2280

ATTGATCAGA AACCTTTGCC AACCACCGAT GCTACAGTTA CATCAACCTT CTGGAGCCAT 2340

GGACTGGCAG AGATGGCAGG GCAGAGAAAT AAGCTGTGTG TCTCTGCCCT AGCTGTGGAT 2400

AACTTTGCAG AGGGGGTGGG CGCTGTGTAT GGCATGTTTG ATGGGGACCG AAACGAGGAG 2460

CTCCCGCGCC TGCTCCAGTG TACCATGGCC GATGTGCTTC TGGAAGAAGT ACAGCAGTCA 2520

ACAAATGACA CGGTTTTCAT GGCTAACACC TTCTTGGTAT CTCACAGGAA ATTGGGAATG 2580

GCTGGCCAGA AGCTGGGCTC TTCCGCTCTC CTCTGTTACA TCCGCCCTGA CACTGCCGAC 2640

CCAACAAGTA GTTTTAGCCT GACTGTTGCC AATGTTGGCA CGTGCCAAGC AGTCCTGTGC 2700

CGCAGTGGGA AAGCAGTGCC CCTCTCGAAA GTCTTCAGCC TGGAGCAGGA CCCAGAGGAG 2760

GCTCAAAGGG TGAAGGACCA GAAAGCCATC ATAACAGAGG ACAACAAGGT GAATGGGGTA 2820

ACCTGCTGTA CCCGGATGCT GGGCTGTACG TACCTCTACC CTTGGATCCT CCCTAAGCCC 2880

CACATATCTG CCACTCCACT TACCCTTCAA GATGAGTTGC TGATTCTGGG AAACAAAGCA 2940

TTGTGGGAAC ACTTGTCATA TACAGAAGCT GTCAACGCAG TGCGCCACGT GCAAGACCCA 3000

TTAGCGGCTG CCAAGAAGCT GTGCACAGTA GCCCAGAGCT ATGGTTGTCA GGACAATGTG 3060

GGGGCGATGG TGGTCTATTT GAACATTGGT GAGGAAGGGT GCACGTGTGA CATGAATGGG 3120

CTCACCCTCC CGGGTCCTGT GGGATTTGCT TCAACCTCCA TCATCAAGGA CCCCCCAAAG 3180

CCAACCACTC CTTCCTCCAG TAGTGGCATC GCCTCGGAGT TTGGCAGCGA GATGTCAACT 3240

TCAGAGGTGA GCAGTGAGGT GGGGTCCACT GCTTCTGATG ACCACAACAC TGTCGGGCTG 3300

GACGCTGGCT TGCTTCCGAG GCCAGAGAGG CGTTGTAGCC TCCATCCAAC ACCCACCTCT 3360

GGGGTGTTTC AGCGCCAGCC TTCTTGTGCG ACTTTTTCAA GTAACCAGTC TGACAATGGC 3420

CTGGACAGTG ATGACGACCA GCCTGTCGAA GGTGTCATAA CAAATGGCAG CAAAGTAGAA 3480

GTAGAAGTAG ATATCCACTG CTGTAGGGGA AGGGGTCTCG AGCACTCGCC CACTCTTATA 3540

GAGAATTCTC CTACCCGATG TCCTGAGGAG CGTGCTAGAG GATCGTTTTT TGGGATCCGA 3600

AGACAGAACA GTGTGAATAG TGGCATACTT CTGCCAGTGA GCAAGGACAG GATGGAGTTA 3660

CAGAAGTCCC CCTCCACTTC CTGTCTCTAT GGAAAGAAAC TCTCGAACGG CTCTATCGTG 3720

CCCCTAGAAG ACAGCCTAAA CCTCATTGAA GTGGCCACAG AAGCACCCAA GAAGAAGACT 3780

GGCTACTTCG CTGCCCCGAC TCAGCTGGAG CCAGAGGATC AGTTTGTTGT ACCTCGTGAC 3840

CTGGAAGAAG AAGTGAAAGA GCAAATGAAG CAACACCAAG AAAGCAGGCC TGAGCCTGAG 3900

CCCAGGGAAG AGGATCGGAC CGAGCTCCCG GAGGAGTTTG ACACGGCACT GTAG 3954

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g+rn+++ ++ +++nf++  +     a++g++DG++++e  + +++++ ++l

Q: 779   SHGLAEMAGQRNKLCVSALAVDNFAEGVG-----AVYGMFDGDRNEELPRLLQCTMADVL  833

         6899*********************9877.....59************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++    ++++ + ++a++Fl  +++l       ++ +k Gs+a++++i+++

Q: 834   LEEVQ----QSTNDTVFMANTFLVSHRKL------GMAGQKLGSSALLCYIRPDtadpts  883

         ***99....77888889************......89***************999999**

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+gkav+ls+ ++ +++ +E +R++++++ +++++  +v+Gv+

Q: 884   sfSLTVANVGTCQAVLCRSGKAVPLSKVFSLEQDpEEAQRVKDQKAIITEDN--KVNGVT  941

         ******************************99866**********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R+lG++yl+p++ p+P+++ ++lt +de liL+ + lw+++s  eav++vr+v +

Q: 942   CCTRMLGCTYLYPWILPKPHISATPLTLQDELLILGNKALWEHLSYTEAVNAVRHVQD--  999

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +aakkL+++a+++g++dnv a+vv

Q: 1000  --PLAAAKKLCTVAQSYGCQDNVGAMVV  1025

         ..************************97

Domain Sequence
(FASTA)

SHGLAEMAGQ RNKLCVSALA VDNFAEGVGA VYGMFDGDRN EELPRLLQCT MADVLLEEVQ 60

QSTNDTVFMA NTFLVSHRKL GMAGQKLGSS ALLCYIRPDT ADPTSSFSLT VANVGTCQAV 120

LCRSGKAVPL SKVFSLEQDP EEAQRVKDQK AIITEDNKVN GVTCCTRMLG CTYLYPWILP 180

KPHISATPLT LQDELLILGN KALWEHLSYT EAVNAVRHVQ DPLAAAKKLC TVAQSYGCQD 240

NVGAMVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>