EKS-AIM-00066

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00066

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	338.9	2.2E-101	4	288	285

Status

Unreviewed

Ensembl Protein

ENSAMEP00000003465

UniProt Accession

G1L994;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK20

Gene Synonyms/Alias

CDK20;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000003286	ENSAMEP00000003465	ENSAMET00000003602

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

346

Protein Sequence
(FASTA)

MDQYCILGRI GEGAHGIVFK AKHVETGEIV ALKKVALRRL EDGIPNQALR EIKALQEIED 60

NQHVVQLKAV FPHGAGFVLA FEFMLSDLAE VVRHAQRPLA QAQVKSYLQM LLRGVAFCHA 120

NNIVHRDLKP ANLLISASGQ LKIADFGLAR VFSPDGSRLY THQVATRWYR APELLYGARQ 180

YDQGVDLWAV GCILGELLNG SPLFPGENDI EQLCCVLRIL GTPSPQVWPE ITELPDYNKI 240

SFKEQAPVPL EEVLPDASPQ ALDLLGQFLL YPPRQRISAS QALLHQYFFT APLPAHPSEL 300

PIPQRPGGPA PKVHPGPPHV HDFHVDRPLE ESLLNPELIR PFIPEG 346

Nucleotide Sequence
(FASTA)

ATGGACCAGT ACTGCATCCT GGGCCGCATC GGGGAGGGCG CGCACGGCAT CGTCTTCAAG 60

GCCAAGCACG TGGAGACTGG AGAGATCGTG GCGCTCAAGA AGGTGGCTCT GCGGCGCCTG 120

GAGGATGGCA TCCCCAACCA GGCCCTGCGG GAGATCAAGG CCCTGCAGGA GATCGAGGAC 180

AATCAGCACG TGGTGCAGCT GAAGGCCGTG TTCCCGCACG GCGCAGGCTT TGTGCTGGCC 240

TTCGAGTTCA TGCTGTCAGA TCTGGCTGAG GTGGTGCGCC ACGCCCAGAG GCCACTGGCC 300

CAGGCACAGG TCAAGAGCTA CCTGCAGATG CTGCTCAGGG GTGTCGCGTT CTGCCATGCC 360

AACAACATCG TGCATCGGGA CCTGAAACCG GCCAACCTGC TCATCAGTGC CTCAGGCCAG 420

CTCAAGATAG CGGACTTTGG CCTGGCCCGG GTGTTTTCCC CAGATGGCAG CCGCCTCTAC 480

ACACACCAGG TGGCCACCAG GTGGTACCGA GCCCCTGAGC TCCTGTACGG CGCCCGCCAG 540

TATGACCAGG GCGTTGACCT GTGGGCTGTG GGCTGCATCC TGGGGGAATT GCTGAACGGA 600

TCCCCTCTCT TTCCTGGGGA GAACGATATC GAACAGCTTT GCTGTGTGCT TCGAATCTTG 660

GGCACCCCCA GCCCTCAAGT CTGGCCGGAG ATCACAGAGC TGCCCGACTA CAACAAGATC 720

TCCTTCAAGG AGCAGGCGCC CGTGCCCCTG GAGGAGGTGC TGCCCGACGC GTCTCCTCAA 780

GCCTTGGACC TGCTGGGGCA GTTCCTCCTC TACCCTCCGC GCCAGCGCAT CTCAGCCTCC 840

CAGGCCCTCC TGCACCAGTA CTTCTTCACG GCTCCCTTGC CTGCCCACCC CTCGGAGCTG 900

CCGATTCCCC AGCGCCCAGG GGGACCTGCC CCCAAGGTCC ACCCAGGGCC ACCCCATGTC 960

CATGACTTCC ACGTGGACCG GCCTCTCGAA GAGTCGCTGT TGAATCCGGA GCTGATTCGG 1020

CCCTTCATTC CAGAGGGCTG A 1041

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkel.khkn  59

         y  l +igeG++g v+kak+ etge+vAlKk++l + ++g+p +alrEi+ l+e+ ++++

Q: 4     YCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIeDNQH  63

         677899*************************************************7899*

S: 60    ivkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         +v+L+ v+  + + ++L fef+ +dL++++++ ++  l +++vks+l++ll+g+a++H+n

Q: 64    VVQLKAVFP-HGAGFVLAFEFMLSDLAEVVRHAQR-PLAQAQVKSYLQMLLRGVAFCHAN  121

         *********.99*******************9999.************************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplkt.ytkevvTlwYraPelLlgakeY  178

         +i+HRDlKp+NlLis++g+lk+aDfGlar fs + ++ yt++v T+wYraPelL+ga++Y

Q: 122   NIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRlYTHQVATRWYRAPELLYGARQY  181

         *******************************8766544**********************

S: 179   stavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ks  237

         ++ vD+W+vgcil ell+ +plf+g+++i+ql  ++++lgtps +vwpe+++lp+y+  s

Q: 182   DQGVDLWAVGCILGELLNGSPLFPGENDIEQLCCVLRILGTPSPQVWPEITELPDYNkIS  241

         *********************************************************88*

S: 238   fpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         f+++++  l+e++++++ +aldll ++l + p++Risa++al h+yf

Q: 242   FKEQAPVPLEEVLPDASPQALDLLGQFLLYPPRQRISASQALLHQYF  288

         **********************************************9

Domain Sequence
(FASTA)

YCILGRIGEG AHGIVFKAKH VETGEIVALK KVALRRLEDG IPNQALREIK ALQEIEDNQH 60

VVQLKAVFPH GAGFVLAFEF MLSDLAEVVR HAQRPLAQAQ VKSYLQMLLR GVAFCHANNI 120

VHRDLKPANL LISASGQLKI ADFGLARVFS PDGSRLYTHQ VATRWYRAPE LLYGARQYDQ 180

GVDLWAVGCI LGELLNGSPL FPGENDIEQL CCVLRILGTP SPQVWPEITE LPDYNKISFK 240

EQAPVPLEEV LPDASPQALD LLGQFLLYPP RQRISASQAL LHQYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

aml:100467235

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013