EKS-AIM-00357

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00357

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/MLK	294.5	6.8E-88	564	820	257

Status

Unreviewed

Ensembl Protein

ENSAMEP00000003593

UniProt Accession

G1L9M0;

Protein Name

Protein Synonyms/Alias

Gene Name

TNNI3K

Gene Synonyms/Alias

TNNI3K;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000003381	ENSAMEP00000003598	ENSAMET00000003739
ENSAMEG00000003381	ENSAMEP00000003593	ENSAMET00000003734
ENSAMEG00000003381	ENSAMEP00000003595	ENSAMET00000003736

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

935

Protein Sequence
(FASTA)

MAAPVAPGVV ALREATQRKL RRFSELRGKP VAAGEFWDIV AITAADEKQE LAYKQQLSEK 60

LKKKELPLGV RYHVFVDPAG AKIGNGGSTL CALRCLEKLY GDKWNSFTIL LIHSDEWKKK 120

VSESYVIIIE RLEDDLQIKE KELAELRHIF SSDDAFSKVN LNYRTENGLS LLHLCCICGG 180

NKSHIRTLML KGLRPSRLTR NGFTALHLAV YKDSAELITS LLHSGADIQQ VGYGGLTALH 240

IATIAGHLEA ADVLLQHGAN VNVQDAVFFT PLHIAAYYGH EQVTRLLLKF GADVNVSGEV 300

GDRPLHLASA KGFFNIAKLL MEEGSKADVN AQDNEDHVPL HFCSRFGHHD IVKYLLQSDS 360

EVQPHVVNIY GDTPLHLACY NGKFDVAKEI IQISGIESLT KENIFSETAF HSACTYGKSI 420

DLVKFLLDQN VISINHQGRD GHTGLHSACY HGHIRLVQFL LDNGADMNLV ACDPSRSSGE 480

KDEQTCLMWA YEKGHDAIVT LLKHYKRPQD ELPCNEYSQP GGDGSYVSLP SPLGKIKSMT 540

KEKADVLLLR AGLPSHFHLQ LSEIEFHEII GSGSFGKVYK GRCRNKIVAI KRYRANTYCS 600

KSDVDMFCRE VSILCRLNHP CVIQFVGACL NDPSQFAIVT QYISGGSLFS LLHEQKRILD 660

LQSKLIIAVD VAKGMEYLHN LTQPIIHRDL NSHNILLCED GHAVVADFGE SRFLQSLDED 720

NMTKQPGNLR WMAPEVFTQC TRYTIKADVF SYALCLWELL TGEIPFAHLK PAAAAADMAY 780

HHIRPPIGYS IPKPISSLLM RGWNACPEGR PEFSEVVTKL EECLCNIELM SPASSNSSGS 840

LSPSSSSDCL VSRGGPGRSH VAALRSRFEL EYALNARSCA SWSQSAGQGS PQGLSLEEMK 900

RGLQFSPVDK YGYVSDPMSP MHFHSCPNSG SFEDS 935

Nucleotide Sequence
(FASTA)

ATGGCTGCTC CCGTTGCCCC CGGAGTCGTA GCTCTGAGAG AAGCCACCCA GCGAAAATTG 60

CGGAGGTTTT CAGAGCTGAG AGGCAAACCT GTGGCAGCTG GAGAATTCTG GGACATTGTT 120

GCAATAACAG CAGCTGATGA AAAACAGGAA CTTGCTTATA AGCAACAGCT GTCAGAAAAG 180

CTGAAAAAAA AGGAGCTACC CCTTGGAGTT CGATATCATG TTTTTGTTGA TCCTGCTGGA 240

GCCAAAATCG GAAATGGAGG ATCCACACTT TGTGCCCTTC GATGTTTGGA AAAGCTATAT 300

GGAGATAAAT GGAATTCTTT TACCATCCTA TTAATTCATT CTGATGAATG GAAGAAGAAA 360

GTCAGTGAAT CTTATGTTAT TATAATAGAA AGATTAGAAG ATGACCTGCA GATCAAAGAA 420

AAAGAACTTG CAGAACTAAG GCACATATTT AGCTCTGATG ATGCCTTCAG TAAAGTCAAC 480

TTAAATTACC GCACAGAAAA TGGGCTGTCT CTACTTCATC TATGCTGCAT TTGTGGAGGC 540

AACAAGTCGC ATATTAGAAC CCTTATGTTA AAAGGGCTTC GTCCATCTCG ACTAACAAGA 600

AATGGATTTA CAGCCTTACA CTTGGCAGTT TACAAGGACA GTGCAGAATT GATCACCTCT 660

CTGCTTCACA GTGGAGCTGA TATACAGCAG GTTGGGTATG GTGGCCTCAC TGCCCTGCAT 720

ATTGCTACAA TAGCTGGTCA CCTGGAGGCT GCTGATGTCC TGCTGCAGCA TGGAGCTAAT 780

GTCAATGTTC AAGATGCAGT TTTTTTCACT CCATTGCACA TTGCAGCATA CTATGGGCAT 840

GAACAGGTAA CCCGCCTTCT TTTGAAATTT GGTGCTGATG TAAATGTAAG TGGTGAAGTT 900

GGAGATAGGC CCCTTCACCT AGCATCTGCA AAAGGATTCT TTAATATTGC AAAACTCTTG 960

ATGGAAGAAG GCAGCAAAGC AGATGTGAAT GCTCAAGACA ATGAAGACCA TGTCCCACTC 1020

CATTTCTGTT CTCGCTTTGG ACACCATGAT ATAGTGAAGT ACCTGCTCCA GAGTGACAGT 1080

GAAGTTCAGC CACATGTGGT TAATATCTAT GGAGATACCC CTTTGCACCT GGCGTGCTAC 1140

AATGGCAAAT TTGACGTTGC CAAGGAAATC ATTCAAATAT CAGGAATTGA AAGCCTGACT 1200

AAAGAAAACA TCTTCAGTGA AACAGCTTTT CACAGTGCTT GTACCTATGG TAAGAGCATT 1260

GACCTGGTTA AATTCCTTCT TGATCAAAAT GTCATAAGCA TTAACCACCA AGGAAGGGAT 1320

GGGCACACAG GATTGCACTC TGCTTGCTAC CATGGTCACA TTCGCCTGGT TCAGTTCTTA 1380

CTGGATAATG GAGCTGATAT GAATCTGGTA GCTTGTGATC CCAGCAGGTC TAGTGGTGAA 1440

AAAGATGAGC AGACATGTTT GATGTGGGCT TATGAAAAAG GACACGATGC AATTGTCACA 1500

CTCCTGAAGC ATTATAAGAG ACCGCAGGAT GAATTGCCTT GTAATGAATA TTCACAGCCT 1560

GGAGGAGATG GTTCCTATGT GTCTCTTCCA TCCCCCTTGG GGAAGATTAA AAGCATGACA 1620

AAAGAGAAGG CAGATGTTCT CCTCCTAAGG GCTGGATTGC CTTCACATTT CCATCTTCAA 1680

CTCTCAGAAA TTGAGTTCCA TGAGATTATC GGCTCAGGTT CTTTTGGGAA AGTATATAAA 1740

GGACGATGCA GAAATAAAAT AGTGGCTATA AAACGTTATC GAGCCAACAC CTACTGCTCC 1800

AAATCAGATG TGGATATGTT TTGCCGAGAG GTGTCCATTC TCTGCCGGCT CAATCATCCC 1860

TGTGTAATTC AGTTTGTGGG TGCTTGCTTG AATGATCCCA GCCAGTTTGC CATCGTCACT 1920

CAGTACATAT CAGGGGGTTC TCTGTTCTCT CTCCTTCATG AACAGAAGAG GATTCTTGAT 1980

TTGCAGTCTA AATTAATTAT TGCAGTAGAT GTTGCCAAAG GTATGGAGTA CCTTCACAAC 2040

CTGACACAGC CAATTATACA CCGTGACTTA AACAGTCACA ATATTCTTCT CTGTGAGGAC 2100

GGGCATGCTG TGGTGGCAGA TTTTGGAGAA TCAAGATTTC TACAGTCTCT GGACGAAGAC 2160

AACATGACAA AACAACCTGG GAACCTCCGC TGGATGGCTC CTGAGGTGTT CACGCAGTGC 2220

ACACGCTACA CCATCAAAGC TGACGTCTTC AGCTACGCTC TGTGTCTGTG GGAACTTCTC 2280

ACCGGTGAAA TTCCATTTGC TCATCTTAAG CCAGCGGCTG CTGCAGCTGA CATGGCTTAC 2340

CACCATATCA GACCTCCCAT TGGCTATTCC ATCCCCAAGC CCATATCGTC TCTGCTGATG 2400

CGAGGGTGGA ATGCATGTCC TGAAGGAAGA CCTGAATTTT CTGAAGTTGT TACCAAGTTA 2460

GAAGAGTGTC TCTGCAACAT AGAGCTGATG TCTCCTGCAT CAAGCAACAG CAGTGGGTCT 2520

CTCTCACCTT CCTCTTCTTC TGACTGCTTG GTGAGCCGGG GAGGGCCTGG ACGGAGCCAC 2580

GTGGCAGCTT TAAGGAGTCG TTTTGAATTG GAATATGCTC TAAATGCAAG GTCCTGTGCT 2640

TCCTGGTCCC AAAGTGCTGG ACAGGGTTCC CCTCAAGGCC TGTCTCTGGA GGAGATGAAG 2700

AGAGGTCTCC AGTTCTCACC CGTTGACAAA TATGGCTACG TGTCTGATCC CATGAGCCCG 2760

ATGCATTTTC ATTCTTGCCC GAATAGTGGC AGCTTTGAGG ACAGC 2805

Domain Profile

S: 1     ieleeligsgafgkvykakwrkkevavKklreeaee.kekleklereakllsklshpnii  59

         ie++e+igsg+fgkvyk+++r+k va+K++r+++++ k+++++++re+++l++l+hp++i

Q: 564   IEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCsKSDVDMFCREVSILCRLNHPCVI  623

         5899****************************99998999********************

S: 60    ellGvcleepn.lllvmeyveggsLsnvlhekskreidlevlvswalqiArGmaYLhsea  118

         +++G+cl++p+ +++v++y++ggsL+++lhe +kr +dl+  + +a+++A+Gm+YLh+ +

Q: 624   QFVGACLNDPSqFAIVTQYISGGSLFSLLHE-QKRILDLQSKLIIAVDVAKGMEYLHNLT  682

         ***********99******************.99*************************6

S: 119   pkkiihrdLksknvLlseekktlkicdFGtarelsk..stkmsaa.gtlawmaPEvl.ke  174

         + +iihrdL+s+n+Ll  e+ ++ ++dFG++r+l++  +++m+++ g+l+wmaPEv+ ++

Q: 683   Q-PIIHRDLNSHNILL-CEDGHAVVADFGESRFLQSldEDNMTKQpGNLRWMAPEVFtQC  740

         6.9*************.89999*************99877777777**************

S: 175   ekvseksDvwSygvvLWelltrevPykdlselaiaykvalkglrlpipsscpeklkkLmk  234

         ++++ k+Dv+Sy+++LWellt+e+P+++l+++a+a+++a++++r+pi+ s+p+++++L+

Q: 741   TRYTIKADVFSYALCLWELLTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLM  800

         ************************************************************

S: 235   ecwnedpekRpsfseivksl  254

         + wn++pe Rp+fse+v++l

Q: 801   RGWNACPEGRPEFSEVVTKL  820

         ****************9875

Domain Sequence
(FASTA)

IEFHEIIGSG SFGKVYKGRC RNKIVAIKRY RANTYCSKSD VDMFCREVSI LCRLNHPCVI 60

QFVGACLNDP SQFAIVTQYI SGGSLFSLLH EQKRILDLQS KLIIAVDVAK GMEYLHNLTQ 120

PIIHRDLNSH NILLCEDGHA VVADFGESRF LQSLDEDNMT KQPGNLRWMA PEVFTQCTRY 180

TIKADVFSYA LCLWELLTGE IPFAHLKPAA AAADMAYHHI RPPIGYSIPK PISSLLMRGW 240

NACPEGRPEF SEVVTKL 257

Keyword

ANK repeat; Complete proteome; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

InterPros

IPR002110	; Ankyrin_rpt.
IPR020683	; Ankyrin_rpt-contain_dom.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.

Pfam

PF00023	; Ank; 2.
PF12796	; Ank_2; 2.
PF07714	; Pkinase_Tyr; 1.

SMARTs

SM00248

; ANK; 10.

Prosites

PS50297	; ANK_REP_REGION; 1.
PS50088	; ANK_REPEAT; 7.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

PR01415

; ANKYRIN.

Created Date

20-Feb-2013