EKS-AIM-00395

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00395

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	522.9	1.8E-157	57	314	258

Status

Unreviewed

Ensembl Protein

ENSAMEP00000003984

UniProt Accession

G1LAR1;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK2

Gene Synonyms/Alias

SGK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000003739	ENSAMEP00000003984	ENSAMET00000004146

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

388

Protein Sequence
(FASTA)

PTTALSCLVP LVSPEPSDHC YRMDSSPAGT PSPQPSRANG NINLGPSANP NARPTDFDFL 60

KVIGKGSYGK VLLAKHKSDG VFYAVKVLQK KSILKKKEQN HIMAERSVLL KNVQHPFLVG 120

LRYSFQTPEK LYFVLDYVNG GELFFHLQRE RRFLEPRARF YAAEVASAIG YLHSLNVIYR 180

DLKPENILLD CQGHVVLTDF GLCKEGVEPE ETTSTFCGTP EYLAPEVLRK EPYDRAVDWW 240

CLGAVLYEML QGLPPFYSQD MSQMYENILY QPLRIPGGQT VAACDLLQGL LHKDQRQRLG 300

SKSDFLEIKN HIFFSPINWD DLYHKRLTPP FNPNVAGPAD LKHFDPEFTQ EAVSKSIGCT 360

PDAVASSSGA SSAFLGFSYA PEDEAILD 388

Nucleotide Sequence
(FASTA)

CCAACAACAG CTCTCTCATG CCTGGTCCCT CTTGTGTCCC CAGAGCCATC TGATCACTGC 60

TATAGAATGG ACTCTAGCCC AGCTGGGACC CCCAGTCCTC AGCCCTCAAG GGCCAATGGG 120

AACATCAACT TGGGACCTTC AGCCAACCCA AATGCCCGGC CCACCGACTT TGACTTCCTG 180

AAAGTCATTG GCAAAGGGAG CTATGGGAAG GTCCTGCTGG CCAAGCACAA GTCTGATGGG 240

GTGTTCTACG CAGTGAAAGT GCTGCAGAAG AAGTCCATCT TAAAGAAGAA AGAGCAGAAC 300

CACATCATGG CGGAGCGCAG TGTGCTTCTG AAGAACGTGC AGCACCCCTT CCTTGTGGGC 360

CTGCGCTACT CCTTCCAGAC GCCTGAGAAG CTCTACTTCG TGCTCGACTA TGTCAACGGG 420

GGAGAGCTCT TCTTCCACCT GCAGCGGGAA CGCCGGTTCC TAGAGCCCCG GGCCCGGTTC 480

TACGCCGCCG AGGTGGCCAG CGCCATCGGC TACCTGCACT CCCTCAATGT CATTTACAGG 540

GACCTGAAAC CAGAGAACAT TCTCTTGGAC TGCCAGGGAC ACGTGGTGCT GACGGATTTT 600

GGCCTCTGCA AGGAAGGTGT AGAGCCTGAG GAGACCACAT CCACGTTCTG TGGCACCCCG 660

GAGTACTTGG CTCCAGAAGT GCTTCGTAAA GAGCCCTATG ATCGGGCAGT GGACTGGTGG 720

TGCTTGGGGG CAGTTCTCTA CGAGATGCTG CAAGGCCTGC CACCATTCTA CAGCCAAGAC 780

ATGTCCCAGA TGTATGAGAA CATTCTGTAT CAGCCACTAC GGATCCCCGG GGGCCAGACC 840

GTGGCTGCCT GTGACCTCCT GCAAGGCCTT CTCCACAAGG ACCAGAGGCA GCGGCTGGGC 900

TCCAAATCAG ACTTTCTTGA GATAAAGAAC CATATATTCT TCAGCCCCAT AAACTGGGAT 960

GACTTGTACC ACAAGAGGCT GACTCCACCC TTCAACCCAA ATGTGGCAGG ACCTGCTGAC 1020

TTGAAACACT TTGACCCAGA GTTCACCCAG GAAGCTGTTT CCAAGTCCAT TGGCTGCACT 1080

CCCGACGCTG TGGCCAGCAG TTCTGGGGCG TCAAGTGCAT TCCTGGGATT TTCCTATGCG 1140

CCAGAGGATG AGGCCATCTT GGAC 1164

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgs+gkvllak+k+d++fyavkvlqkk+ilkkke++himaer+vllknv+hp

Q: 57    FDFLKVIGKGSYGKVLLAKHKSDGVFYAVKVLQKKSILKKKEQNHIMAERSVLLKNVQHP  116

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvgl+ysfqt+eklyfvldyvnggelffhlqrer+fleprarfyaae+asa+gylhsln

Q: 117   FLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLN  176

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ++yrdlkpenilld++ghvvltdfglcke++e e+ttstfcgtpeylapevlrk+pydr+

Q: 177   VIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEETTSTFCGTPEYLAPEVLRKEPYDRA  236

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyeml glppfys+d+++my+nil +pl++++g +vaa++ll++ll+kd++

Q: 237   VDWWCLGAVLYEMLQGLPPFYSQDMSQMYENILYQPLRIPGGQTVAACDLLQGLLHKDQR  296

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlg+k dfleiknh+ff

Q: 297   QRLGSKSDFLEIKNHIFF  314

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SYGKVLLAKH KSDGVFYAVK VLQKKSILKK KEQNHIMAER SVLLKNVQHP 60

FLVGLRYSFQ TPEKLYFVLD YVNGGELFFH LQRERRFLEP RARFYAAEVA SAIGYLHSLN 120

VIYRDLKPEN ILLDCQGHVV LTDFGLCKEG VEPEETTSTF CGTPEYLAPE VLRKEPYDRA 180

VDWWCLGAVL YEMLQGLPPF YSQDMSQMYE NILYQPLRIP GGQTVAACDL LQGLLHKDQR 240

QRLGSKSDFL EIKNHIFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0015459	; F:potassium channel regulator activity
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013