EKS-AIM-00389

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00389

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	436.9	2.4E-131	35	293	259

Status

Unreviewed

Ensembl Protein

ENSAMEP00000005112

UniProt Accession

D2H630;

Protein Name

Protein Synonyms/Alias

Gene Name

STK17B

Gene Synonyms/Alias

STK17B; PANDA_005401;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000004835	ENSAMEP00000005112	ENSAMET00000005321

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

372

Protein Sequence
(FASTA)

MSRRRFDCRS ISGLLTTTPQ TPMKTENFNN FYTLTSKELG RGKFAVVRQC ISKSTGQEYA 60

AKFLKKRRRG QDCRAEILHE IAILELAKSC PHVINLHEVY ENASEIILIL EYAAGGEIFN 120

LCLPELAEMV SENDIIRLIK QILEGVCYLH QNNIVHLDLK PQNILLSSIY PLGDIKIVDF 180

GMSRKIGNAC ELREIMGTPE YLAPEILNYD PITTATDMWN IGIIAYMLLT HTSPFVGEDN 240

QETYLNISQV NVDYSEETFS SVSQLATDFI QRLLVKNPEK RPTAEICLSH SWLQQWDFGN 300

LFHPEETSNS SQSQDHSLRS SEDKTSKSSC NGTCSDREDK ENIPEDSSMV SKRFRFDNSL 360

PNPHELVSDL LC 372

Nucleotide Sequence
(FASTA)

ATGTCGAGGA GGAGATTTGA TTGCCGAAGT ATTTCAGGCT TGCTAACTAC AACTCCTCAA 60

ACTCCAATGA AAACGGAAAA CTTTAATAAT TTTTATACAC TTACATCTAA AGAGCTGGGA 120

AGAGGAAAAT TTGCTGTGGT GAGACAATGT ATATCAAAAT CTACTGGCCA AGAATATGCT 180

GCAAAATTTC TAAAAAAGAG AAGAAGAGGG CAGGATTGTC GAGCAGAGAT TCTACATGAA 240

ATTGCCATAC TTGAGTTGGC AAAGTCTTGT CCTCACGTAA TTAATCTTCA TGAAGTCTAT 300

GAAAATGCTA GTGAAATCAT TTTGATACTG GAATATGCTG CAGGTGGAGA AATTTTCAAC 360

TTGTGTTTAC CTGAGCTGGC TGAAATGGTT TCTGAAAATG ACATTATCAG ACTCATTAAA 420

CAAATACTTG AAGGAGTTTG TTATCTACAT CAGAATAACA TTGTACACCT TGATTTGAAG 480

CCACAGAATA TATTATTGAG CAGCATATAC CCTCTTGGAG ATATAAAAAT TGTAGATTTT 540

GGAATGTCTC GAAAAATAGG GAATGCATGT GAACTTCGGG AAATCATGGG AACACCAGAA 600

TACTTAGCTC CAGAAATCCT GAACTATGAT CCTATTACCA CAGCAACAGA TATGTGGAAT 660

ATTGGCATAA TAGCATATAT GTTGTTAACT CATACATCTC CATTTGTGGG AGAAGATAAT 720

CAAGAAACAT ACCTCAATAT TTCTCAAGTT AATGTAGATT ATTCAGAAGA AACTTTTTCA 780

TCAGTTTCAC AGCTGGCCAC AGATTTTATC CAGAGGCTTT TAGTAAAAAA TCCAGAGAAA 840

AGACCAACAG CAGAAATCTG CCTGTCTCAT TCTTGGCTAC AGCAGTGGGA CTTTGGAAAT 900

TTATTTCACC CTGAAGAAAC TTCCAATTCC TCTCAAAGTC AAGATCATTC TTTAAGGTCC 960

TCTGAAGACA AAACTTCTAA ATCCTCCTGT AATGGAACCT GTAGTGATCG AGAAGACAAG 1020

GAGAATATTC CAGAGGATAG CAGCATGGTT TCCAAAAGAT TTCGCTTTGA TAACTCATTG 1080

CCCAATCCCC ATGAACTTGT TTCAGATTTG CTGTGTTAG 1119

Domain Profile

S: 3     tgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirse  62

         t+kelg+Gkfavvr+c++kstG+eyaakflkkrr    r++++r+ei +e+a+l++++s+

Q: 35    TSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRR----RGQDCRAEILHEIAILELAKSC  90

         789*******************************....**********************

S: 63    pnvinlhevyenksdvililelvaGGelfd..llaekeslseeeatellkqilegvkylh  120

         p+vinlhevyen+s++ilile++aGGe+f+  l + +e++se+++++l+kqilegv ylh

Q: 91    PHVINLHEVYENASEIILILEYAAGGEIFNlcLPELAEMVSENDIIRLIKQILEGVCYLH  150

         ******************************877899************************

S: 121   skkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivny  180

         +++ivhldlkP+nill++ + p gdik++dfG+srki +++el+ei+GtPe++aPei+ny

Q: 151   QNNIVHLDLKPQNILLSSIY-PLGDIKIVDFGMSRKIGNACELREIMGTPEYLAPEILNY  209

         ********************.***************************************

S: 181   eplsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdf  240

         +p++++tdmw+iG+i+y+ll+++sPf+G+++qet+lnis+vn+d+see+fssvs+la+df

Q: 210   DPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDF  269

         ************************************************************

S: 241   irrllvkdpekrltieeclehswl  264

         i+rllvk+pekr t+e cl+hswl

Q: 270   IQRLLVKNPEKRPTAEICLSHSWL  293

         ***********************7

Domain Sequence
(FASTA)

TSKELGRGKF AVVRQCISKS TGQEYAAKFL KKRRRGQDCR AEILHEIAIL ELAKSCPHVI 60

NLHEVYENAS EIILILEYAA GGEIFNLCLP ELAEMVSEND IIRLIKQILE GVCYLHQNNI 120

VHLDLKPQNI LLSSIYPLGD IKIVDFGMSR KIGNACELRE IMGTPEYLAP EILNYDPITT 180

ATDMWNIGII AYMLLTHTSP FVGEDNQETY LNISQVNVDY SEETFSSVSQ LATDFIQRLL 240

VKNPEKRPTA EICLSHSWL 259

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006917	; P:induction of apoptosis

KEGG

aml:100469412

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013