EKS-AIM-00074

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-AIM-00074

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/GSK	448.6	8.8E-135	120	403	284

Status

Unreviewed

Ensembl Protein

ENSAMEP00000005200

UniProt Accession

G1LE72;

Protein Name

Protein Synonyms/Alias

Gene Name

ERF

Gene Synonyms/Alias

ERF;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSAMEG00000004880	ENSAMEP00000005206	ENSAMET00000005421
ENSAMEG00000004880	ENSAMEP00000005200	ENSAMET00000005415

Organism

Ailuropoda melanoleuca

Functional Description

Protein Length

483

Protein Sequence
(FASTA)

EGGGGPAGGL EDEVGMRHVS WQHRCNGVGG GGVTKKGGCY HGGGGGGGGK ASVGAMGGGV 60

GASSSGGGPS GSGGGGGGAP GAGTSFPPPG VKLGRDSGKV TTVVATLGQG PERSQEVAYT 120

DIKVIGNGSF GVVYQARLAE TRELVAIKKV LQDKRFKNRE LQIMRKLDHC NIVRLRYFFY 180

SSGEKKDELY LNLVLEYVPE TVYRVARHFT KAKLTIPIIY VKVYMYQLFR SLAYIHSQGV 240

CHRDIKPQNL LVDPDTAVLK LCDFGSAKQL VRGEPNVSYI CSRYYRAPEL IFGATDYTSS 300

IDVWSAGCVL AELLLGQPIF PGDSGVDQLV EIIKVLGTPT REQIREMNPN YTEFKFPQIK 360

AHPWTKVFKS RTPPEAIALC SSLLEYTPSS RLSPLEACAH SFFDELRCHG TQLPNNRPLP 420

PLFNFSPGEL SIQPSLNAIL IPPHLRSPAG TATLTPSSQA LSEAQTGPDW QSTDATAPLT 480

NSS 483

Nucleotide Sequence
(FASTA)

GAAGGGGGTG GGGGCCCCGC TGGGGGCCTG GAGGATGAGG TTGGGATGAG GCATGTCTCC 60

TGGCAACATA GATGCAACGG AGTTGGTGGT GGTGGTGTGA CGAAGAAAGG GGGATGTTAT 120

CATGGGGGGG GGGGGGGGGG GGGGGGAAAG GCGTCAGTCG GAGCCATGGG TGGGGGCGTG 180

GGGGCCTCGA GCTCCGGGGG TGGCCCCAGC GGCAGCGGCG GGGGAGGGGG GGGGGCGCCC 240

GGTGCGGGCA CTAGCTTCCC GCCGCCCGGA GTGAAGCTGG GCCGTGACAG CGGGAAGGTG 300

ACCACAGTGG TAGCCACTCT AGGCCAAGGC CCGGAGCGCT CCCAGGAGGT GGCTTACACA 360

GACATCAAAG TGATTGGCAA TGGCTCTTTT GGGGTCGTGT ACCAGGCACG CCTGGCTGAG 420

ACCAGGGAAC TGGTGGCCAT CAAGAAGGTT CTCCAGGACA AGAGGTTCAA GAACCGAGAG 480

CTGCAGATTA TGCGTAAGCT GGACCACTGC AATATCGTGA GGCTGAGATA CTTCTTCTAC 540

TCCAGTGGGG AGAAGAAAGA CGAGCTTTAT CTAAATCTGG TGCTGGAATA CGTGCCCGAG 600

ACAGTGTACC GGGTGGCCCG CCATTTCACC AAGGCCAAGT TGACCATCCC CATCATCTAT 660

GTCAAGGTGT ACATGTACCA GCTCTTCCGG AGCTTGGCCT ACATCCACTC CCAGGGGGTG 720

TGTCACCGTG ACATCAAGCC CCAGAACCTG CTGGTGGACC CCGACACTGC TGTCCTCAAG 780

CTCTGCGATT TTGGCAGTGC AAAGCAGCTG GTCCGGGGGG AGCCCAACGT CTCCTACATC 840

TGTTCTCGCT ACTACCGGGC CCCGGAGCTG ATCTTTGGAG CCACTGATTA CACGTCGTCC 900

ATTGATGTGT GGTCAGCTGG CTGCGTACTG GCGGAGCTCC TCCTGGGCCA GCCCATCTTC 960

CCTGGGGACA GTGGGGTAGA CCAGCTGGTG GAGATCATCA AGGTGCTGGG AACACCAACC 1020

CGGGAACAGA TCCGAGAGAT GAACCCCAAC TACACGGAGT TCAAGTTTCC CCAGATTAAA 1080

GCTCATCCCT GGACAAAGGT GTTCAAATCT CGAACGCCGC CAGAGGCCAT CGCACTCTGC 1140

TCTAGCCTGC TGGAGTACAC ACCGTCCTCA AGGCTCTCCC CCCTGGAAGC CTGCGCCCAC 1200

AGCTTCTTTG ATGAATTGCG ATGTCATGGA ACCCAGCTCC CCAACAACCG CCCGCTTCCC 1260

CCGCTCTTCA ATTTCAGTCC TGGAGAACTC TCCATCCAGC CATCTCTCAA CGCCATTCTC 1320

ATCCCTCCTC ACTTGAGGTC TCCAGCGGGC ACTGCCACCC TCACTCCATC CTCACAAGCT 1380

TTAAGTGAGG CTCAGACCGG CCCGGACTGG CAGTCGACCG ACGCCACAGC TCCACTCACT 1440

AACTCTTCCT GA 1452

Domain Profile

S: 2     eelkligsGsFgnVyqavlseesekevaiKkvlqdkklknlEleilrklkHknivrLlyf  61

         +++k+ig+GsFg+Vyqa+l+e++e  vaiKkvlqdk++kn+El+i+rkl+H+nivrL+yf

Q: 120   TDIKVIGNGSFGVVYQARLAETREL-VAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYF  178

         789**********************.**********************************

S: 62    fsksaekkdkvylnlvleylPetlakvlrelkdkkkkldvlevklytyQlfrglaylhsl  121

         f++s ekkd++ylnlvley+Pet+++v+r+++++k ++++++vk+y+yQlfr+lay+hs+

Q: 179   FYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPIIYVKVYMYQLFRSLAYIHSQ  238

         ************************************************************

S: 122   eivHrDiKPqNllvdeetgvlKlcDfGsakrleknepnvsYivsRyYRaPELllgakeyt  181

         +++HrDiKPqNllvd++t+vlKlcDfGsak+l+++epnvsYi+sRyYRaPEL++ga++yt

Q: 239   GVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYT  298

         ************************************************************

S: 182   tkiDvWsagcvlaEllkgkvlfkgksakdqlelivkvlGtptkedikemnvkykekkfkk  241

         ++iDvWsagcvlaEll+g+++f+g+s++dql++i+kvlGtpt+e+i+emn++y+e+kf++

Q: 299   SSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQ  358

         ************************************************************

S: 242   ikkvslakvlkkkedkeavdllkkilkyepkkRlsalellahpff  286

         ik+++++kv+k+++++ea++l++++l+y+p++Rls+le++ah+ff

Q: 359   IKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLSPLEACAHSFF  403

         ********************************************9

Domain Sequence
(FASTA)

TDIKVIGNGS FGVVYQARLA ETRELVAIKK VLQDKRFKNR ELQIMRKLDH CNIVRLRYFF 60

YSSGEKKDEL YLNLVLEYVP ETVYRVARHF TKAKLTIPII YVKVYMYQLF RSLAYIHSQG 120

VCHRDIKPQN LLVDPDTAVL KLCDFGSAKQ LVRGEPNVSY ICSRYYRAPE LIFGATDYTS 180

SIDVWSAGCV LAELLLGQPI FPGDSGVDQL VEIIKVLGTP TREQIREMNP NYTEFKFPQI 240

KAHPWTKVFK SRTPPEAIAL CSSLLEYTPS SRLSPLEACA HSFF 284

Keyword

Complete proteome; DNA-binding; Nucleus; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0043565	; F:sequence-specific DNA binding
GO:0003700	; F:sequence-specific DNA binding transcription factor activity
GO:0003714	; F:transcription corepressor activity
GO:0000122	; P:negative regulation of transcription from RNA polymerase II promoter

KEGG

aml:100472781

;

InterPros

IPR000418	; Ets.
IPR011991	; WHTH_trsnscrt_rep_DNA-bd.

Pfam

PF00178

; Ets; 1.

SMARTs

SM00413

; ETS; 1.

Prosites

PS00345	; ETS_DOMAIN_1; 1.
PS00346	; ETS_DOMAIN_2; 1.
PS50061	; ETS_DOMAIN_3; 1.

Prints

PR00454

; ETSDOMAIN.

Created Date

20-Feb-2013